DK1639130T3 - Prober, biblioteker og kits til analyse af blandinger af nukleinsyrer og metoder til opbygning af disse - Google Patents
Prober, biblioteker og kits til analyse af blandinger af nukleinsyrer og metoder til opbygning af disseInfo
- Publication number
- DK1639130T3 DK1639130T3 DK04738926.7T DK04738926T DK1639130T3 DK 1639130 T3 DK1639130 T3 DK 1639130T3 DK 04738926 T DK04738926 T DK 04738926T DK 1639130 T3 DK1639130 T3 DK 1639130T3
- Authority
- DK
- Denmark
- Prior art keywords
- nucleic acid
- methods
- kits
- libraries
- building
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B25/00—ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
- G16B25/20—Polymerase chain reaction [PCR]; Primer or probe design; Probe optimisation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1065—Preparation or screening of tagged libraries, e.g. tagged microorganisms by STM-mutagenesis, tagged polynucleotides, gene tags
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B25/00—ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
Applications Claiming Priority (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DKPA200300933 | 2003-06-20 | ||
DKPA200301066 | 2003-07-12 | ||
DKPA200400242 | 2004-02-17 | ||
DKPA200400353 | 2004-03-01 | ||
US54934604P | 2004-03-02 | 2004-03-02 | |
PCT/DK2004/000429 WO2004113563A2 (en) | 2003-06-20 | 2004-06-18 | Probes, libraries and kits for analysis of mixtures of nucleic acids and methods for constructing the same |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1639130T3 true DK1639130T3 (da) | 2012-07-09 |
Family
ID=45935360
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK04738926.7T DK1639130T3 (da) | 2003-06-20 | 2004-06-18 | Prober, biblioteker og kits til analyse af blandinger af nukleinsyrer og metoder til opbygning af disse |
Country Status (5)
Country | Link |
---|---|
US (2) | US20050089889A1 (da) |
CN (1) | CN1833034B (da) |
AT (1) | ATE553216T1 (da) |
DK (1) | DK1639130T3 (da) |
ES (1) | ES2385828T3 (da) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20060166238A1 (en) * | 2004-12-22 | 2006-07-27 | Ramsing Niels B | Probes, libraries and kits for analysis of mixtures of nucleic acids and methods for constructing the same |
US20070067110A1 (en) * | 2005-09-21 | 2007-03-22 | Nelson Charles F Iii | Generation of negative controls for arrays |
WO2007136834A2 (en) * | 2006-05-19 | 2007-11-29 | Codon Devices, Inc. | Combined extension and ligation for nucleic acid assembly |
WO2008027558A2 (en) * | 2006-08-31 | 2008-03-06 | Codon Devices, Inc. | Iterative nucleic acid assembly using activation of vector-encoded traits |
US9157116B2 (en) * | 2008-02-08 | 2015-10-13 | Fluidigm Corporation | Combinatorial amplification and detection of nucleic acids |
CN101659952B (zh) * | 2009-07-14 | 2012-07-18 | 上海之江生物科技有限公司 | 锁核酸和小沟结合物共修饰核酸片段 |
CN102409043B (zh) * | 2010-09-21 | 2013-12-04 | 深圳华大基因科技服务有限公司 | 高通量低成本Fosmid文库构建的方法及其所使用标签和标签接头 |
CN102409408B (zh) * | 2010-09-21 | 2013-08-07 | 深圳华大基因科技服务有限公司 | 一种利用微量基因组dna进行全基因组甲基化位点精确检测的方法 |
ES2548400T3 (es) | 2010-11-12 | 2015-10-16 | Gen9, Inc. | Métodos y dispositivos para la síntesis de ácidos nucleicos |
EP2637780B1 (en) | 2010-11-12 | 2022-02-09 | Gen9, Inc. | Protein arrays and methods of using and making the same |
WO2013032850A2 (en) | 2011-08-26 | 2013-03-07 | Gen9, Inc. | Compositions and methods for high fidelity assembly of nucleic acids |
US9150853B2 (en) | 2012-03-21 | 2015-10-06 | Gen9, Inc. | Methods for screening proteins using DNA encoded chemical libraries as templates for enzyme catalysis |
CA2871505C (en) | 2012-04-24 | 2021-10-12 | Gen9, Inc. | Methods for sorting nucleic acids and multiplexed preparative in vitro cloning |
LT2864531T (lt) | 2012-06-25 | 2019-03-12 | Gen9, Inc. | Nukleorūgšties konstravimo ir aukšto produktyvumo sekvenavimo būdai |
CN103484458A (zh) * | 2013-10-10 | 2014-01-01 | 东南大学 | 一种含通用碱基寡核苷酸序列及其在dna杂交分析中的应用 |
EP3227476B1 (en) * | 2014-12-02 | 2021-02-24 | Tribiotica Llc | Methods and kits for theranostic applications |
CN105297145B (zh) * | 2015-11-06 | 2019-03-08 | 艾吉泰康生物科技(北京)有限公司 | 一种制备基因dna探针文库的方法和试剂盒 |
JP6685138B2 (ja) * | 2016-01-27 | 2020-04-22 | シスメックス株式会社 | 核酸増幅の精度管理方法、精度管理用試薬およびその試薬キット |
WO2018194342A2 (en) * | 2017-04-17 | 2018-10-25 | Seegene, Inc. . | Methods for preparing optimal combination of oligonucleotides |
CN112402592B (zh) * | 2020-12-04 | 2023-06-02 | 中国人民解放军陆军军医大学 | Spink7蛋白在制备促进过度炎症创面愈合的药物中的应用 |
CN112480242B (zh) * | 2020-12-04 | 2023-06-06 | 中国人民解放军陆军军医大学 | Spink7蛋白在制备预防和/或治疗溃疡性结肠炎的药物中的应用 |
CN113322254B (zh) * | 2021-01-06 | 2022-05-20 | 南京诺唯赞生物科技股份有限公司 | 多靶点蛋白质-dna相互作用的研究方法和工具 |
US20220229819A1 (en) * | 2021-01-21 | 2022-07-21 | Applied Materials, Inc. | Methods, mediums, and systems for configuring a dna/rna target probe design |
CN113699155B (zh) * | 2021-10-29 | 2022-02-11 | 和元生物技术(上海)股份有限公司 | 一种CuO突变体及其应用 |
US20240093308A1 (en) * | 2022-08-01 | 2024-03-21 | Idexx Laboratories, Inc. | Human Fractional Abundance Assays |
Family Cites Families (34)
Publication number | Priority date | Publication date | Assignee | Title |
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US3687808A (en) * | 1969-08-14 | 1972-08-29 | Univ Leland Stanford Junior | Synthetic polynucleotides |
US4889818A (en) * | 1986-08-22 | 1989-12-26 | Cetus Corporation | Purified thermostable enzyme |
US5432272A (en) * | 1990-10-09 | 1995-07-11 | Benner; Steven A. | Method for incorporating into a DNA or RNA oligonucleotide using nucleotides bearing heterocyclic bases |
US6582908B2 (en) * | 1990-12-06 | 2003-06-24 | Affymetrix, Inc. | Oligonucleotides |
CN1066519A (zh) * | 1991-05-03 | 1992-11-25 | 上海工业大学 | 微机硬盘写保护卡 |
US5912340A (en) | 1995-10-04 | 1999-06-15 | Epoch Pharmaceuticals, Inc. | Selective binding complementary oligonucleotides |
ATE232880T1 (de) * | 1996-11-18 | 2003-03-15 | Takeshi Imanishi | Neue nucleotidanaloga |
JPH10234381A (ja) * | 1997-02-28 | 1998-09-08 | Shinkinrui Kinou Kaihatsu Kenkyusho:Kk | リゾクトニア属菌検出用の核酸配列 |
JP3756313B2 (ja) * | 1997-03-07 | 2006-03-15 | 武 今西 | 新規ビシクロヌクレオシド及びオリゴヌクレオチド類縁体 |
US7572582B2 (en) * | 1997-09-12 | 2009-08-11 | Exiqon A/S | Oligonucleotide analogues |
US6794499B2 (en) * | 1997-09-12 | 2004-09-21 | Exiqon A/S | Oligonucleotide analogues |
EP2253639A1 (en) | 1997-09-12 | 2010-11-24 | Exiqon A/S | Bi- and tri-cyclic nucleoside, nucleotide and oligonucleoide analogues |
DE69942444D1 (de) * | 1998-02-04 | 2010-07-15 | Life Technologies Corp | Bestimmung des genotyps eines amplifikationsproduktes an mehreren allelen stellen |
US6322976B1 (en) * | 1998-05-28 | 2001-11-27 | Medical Research Council | Compositions and methods of disease diagnosis and therapy |
WO1999065928A2 (en) * | 1998-06-19 | 1999-12-23 | Genzyme Corporation | Polynucleotide population isolated from non-metastatic and metastatic breast tumor tissues |
US7071324B2 (en) * | 1998-10-13 | 2006-07-04 | Brown University Research Foundation | Systems and methods for sequencing by hybridization |
ATE287897T2 (de) | 1999-02-12 | 2005-02-15 | Sankyo Co | Analoga von nukleosiden und oligonukleotiden |
US7084125B2 (en) * | 1999-03-18 | 2006-08-01 | Exiqon A/S | Xylo-LNA analogues |
EP1161439B1 (en) | 1999-03-18 | 2010-04-21 | Exiqon A/S | Xylo-lna analogues |
DK1163250T3 (da) | 1999-03-24 | 2006-11-13 | Exiqon As | Forbedret syntese af [2.2.1]bicyclonukleosider |
US6734291B2 (en) * | 1999-03-24 | 2004-05-11 | Exiqon A/S | Synthesis of [2.2.1]bicyclo nucleosides |
NZ514348A (en) | 1999-05-04 | 2004-05-28 | Exiqon As | L-ribo-LNA analogues |
AU5429000A (en) | 1999-06-25 | 2001-01-31 | Sankyo Company Limited | Novel bicyclonucleoside derivatives |
EP1072679A3 (en) | 1999-07-20 | 2002-07-31 | Agilent Technologies, Inc. (a Delaware corporation) | Method of producing nucleic acid molecules with reduced secondary structure |
JP4151751B2 (ja) | 1999-07-22 | 2008-09-17 | 第一三共株式会社 | 新規ビシクロヌクレオシド類縁体 |
US6579680B2 (en) * | 2000-02-28 | 2003-06-17 | Corning Incorporated | Method for label-free detection of hybridized DNA targets |
IL154129A0 (en) | 2000-07-28 | 2003-07-31 | Compugen Inc | Oligonucleotide library for detecting rna transcripts and splice variants that populate a transcriptome |
US20020197630A1 (en) * | 2001-04-12 | 2002-12-26 | Knapp Michael R. | Systems and methods for high throughput genetic analysis |
JP2002360247A (ja) | 2001-06-13 | 2002-12-17 | Takara Bio Inc | 核酸固定化物 |
JP2005514005A (ja) | 2001-09-04 | 2005-05-19 | エクシコン エ/エス | 新規のlna組成物およびその使用 |
AU2002351077A1 (en) | 2001-11-05 | 2003-05-19 | Exiqon A/S | Oligonucleotides modified with novel alpha-l-rna analogues |
US7569575B2 (en) * | 2002-05-08 | 2009-08-04 | Santaris Pharma A/S | Synthesis of locked nucleic acid derivatives |
WO2004026804A1 (en) * | 2002-09-20 | 2004-04-01 | Integrated Dna Technologies, Inc. | Anthraquinone quencher dyes, their methods of preparation and use |
US20040219565A1 (en) | 2002-10-21 | 2004-11-04 | Sakari Kauppinen | Oligonucleotides useful for detecting and analyzing nucleic acids of interest |
-
2004
- 2004-06-18 DK DK04738926.7T patent/DK1639130T3/da active
- 2004-06-18 AT AT04738926T patent/ATE553216T1/de active
- 2004-06-18 CN CN200480022775.3A patent/CN1833034B/zh active Active
- 2004-06-18 US US10/871,471 patent/US20050089889A1/en not_active Abandoned
- 2004-06-18 ES ES04738926T patent/ES2385828T3/es active Active
-
2016
- 2016-09-23 US US15/273,917 patent/US11111535B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
CN1833034B (zh) | 2014-04-16 |
US20170081719A1 (en) | 2017-03-23 |
US20050089889A1 (en) | 2005-04-28 |
ATE553216T1 (de) | 2012-04-15 |
ES2385828T3 (es) | 2012-08-01 |
CN1833034A (zh) | 2006-09-13 |
US11111535B2 (en) | 2021-09-07 |
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