DK1604991T3 - Antitumorvirkningsforstærker og antitumormiddel - Google Patents
Antitumorvirkningsforstærker og antitumormiddelInfo
- Publication number
- DK1604991T3 DK1604991T3 DK04719589T DK04719589T DK1604991T3 DK 1604991 T3 DK1604991 T3 DK 1604991T3 DK 04719589 T DK04719589 T DK 04719589T DK 04719589 T DK04719589 T DK 04719589T DK 1604991 T3 DK1604991 T3 DK 1604991T3
- Authority
- DK
- Denmark
- Prior art keywords
- antitumor
- tumor
- antitumor effect
- agent
- administering
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/52—Two oxygen atoms
- C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
- C07D239/545—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/553—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms with halogen atoms or nitro radicals directly attached to ring carbon atoms, e.g. fluorouracil
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Urology & Nephrology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
- Saccharide Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2003070097 | 2003-03-14 | ||
| PCT/JP2004/003189 WO2004081012A1 (ja) | 2003-03-14 | 2004-03-11 | 抗腫瘍効果増強剤及び抗腫瘍剤 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1604991T3 true DK1604991T3 (da) | 2009-01-05 |
Family
ID=32984641
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK04719589T DK1604991T3 (da) | 2003-03-14 | 2004-03-11 | Antitumorvirkningsforstærker og antitumormiddel |
Country Status (21)
| Country | Link |
|---|---|
| US (2) | US9611227B2 (de) |
| EP (1) | EP1604991B1 (de) |
| JP (1) | JP4610481B2 (de) |
| KR (1) | KR100812693B1 (de) |
| CN (2) | CN1761665A (de) |
| AT (1) | ATE408408T1 (de) |
| AU (1) | AU2004220205B2 (de) |
| BR (1) | BRPI0408372A (de) |
| CA (1) | CA2518195C (de) |
| CY (1) | CY1108395T1 (de) |
| DE (1) | DE602004016636D1 (de) |
| DK (1) | DK1604991T3 (de) |
| ES (1) | ES2312978T3 (de) |
| MX (1) | MXPA05009781A (de) |
| NZ (1) | NZ542150A (de) |
| PL (1) | PL1604991T3 (de) |
| PT (1) | PT1604991E (de) |
| RU (1) | RU2334517C2 (de) |
| SI (1) | SI1604991T1 (de) |
| TW (1) | TW200503720A (de) |
| WO (1) | WO2004081012A1 (de) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ562048A (en) * | 2005-04-01 | 2011-12-22 | Taiho Pharmaceutical Co Ltd | Potentiator for radiation therapy comprising pyridine derivative active ingredient |
| TWI434700B (zh) * | 2005-04-01 | 2014-04-21 | Taiho Pharmaceutical Co Ltd | 放射線治療增強劑 |
| WO2007043531A1 (ja) * | 2005-10-07 | 2007-04-19 | Celestar Lexico-Sciences, Inc. | 抗腫瘍剤及び放射線併用療法感受性診断用遺伝子マーカー並びにその利用 |
| WO2009139085A1 (ja) | 2008-05-12 | 2009-11-19 | 静岡県 | 抗腫瘍剤、キット及び癌治療方法 |
| JP5553522B2 (ja) * | 2009-03-31 | 2014-07-16 | 大鵬薬品工業株式会社 | 経口投与用医薬組成物 |
| TW201043237A (en) * | 2009-04-22 | 2010-12-16 | Taiho Pharmaceutical Co Ltd | Method for predicting a therapeutic effect of the chemotherapy for renal cell cancer |
| CN102309491B (zh) * | 2010-07-02 | 2015-06-10 | 天津金耀集团有限公司 | 一种替加氟、吉美斯特复方注射液 |
| SG10201505503WA (en) * | 2011-05-25 | 2015-09-29 | Taiho Pharmaceutical Co Ltd | Dry-coated tablet containing tegafur, gimeracil and oteracil potassium |
| TWI667237B (zh) * | 2013-09-30 | 2019-08-01 | 日商大鵬藥品工業股份有限公司 | 使用氮雜雙環化合物之癌併用療法 |
| CN106692173A (zh) * | 2015-11-18 | 2017-05-24 | 北京诺普德医药科技有限公司 | 一种抗肿瘤复方组合物及其应用 |
| CN106581001B (zh) * | 2016-11-03 | 2018-12-21 | 江苏恒瑞医药股份有限公司 | 一种替吉奥组合物的制备方法 |
| KR102258514B1 (ko) | 2019-09-23 | 2021-05-31 | 연세대학교 산학협력단 | 신규한 다층형 좌약 제제 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1990007334A1 (en) | 1989-01-05 | 1990-07-12 | Otsuka Pharmaceutical Co., Ltd. | Non-injection carcinostatic agent for suppressing occurrence of inflammation due to 5-fluorouracil and method for curing cancer |
| DE69121551T2 (de) * | 1990-09-07 | 1997-01-02 | Taiho Pharmaceutical Co Ltd | Antineoplastisch wirkender und den antineoplastischen effekt verstärkender wirkstoff |
| JP2614164B2 (ja) | 1991-05-27 | 1997-05-28 | 大鵬薬品工業株式会社 | 抗腫瘍効果増強のための及び腫瘍治療のための組成物 |
| CH683262A5 (it) * | 1992-01-22 | 1994-02-15 | Applied Pharma Res | Procedimento per la separazione dei diastereomeri del sale di calcio dell'acido (6(R,S)-N-formiltetraidrofolico). |
| WO2001066102A2 (en) * | 2000-03-08 | 2001-09-13 | Bristol-Myers Squibb Company | Oral dosage form for administration of the combination of tegafur, uracil, folinic acid, and oxaliplatin and method of using the same |
| MXPA03007989A (es) | 2001-03-06 | 2003-12-04 | Bristol Myers Squibb Co | Metodo y forma de dosificacion para tratamiento de tumores por administracion de tegafur, uracil, acido folinico, paclitaxel y carboplatin. |
| US20040265813A1 (en) * | 2001-07-05 | 2004-12-30 | Teiji Takechi | Dna arrays for measuring sensitivity to anticancer agent |
-
2004
- 2004-03-11 NZ NZ542150A patent/NZ542150A/xx not_active IP Right Cessation
- 2004-03-11 BR BRPI0408372-5A patent/BRPI0408372A/pt not_active Application Discontinuation
- 2004-03-11 EP EP04719589A patent/EP1604991B1/de not_active Expired - Lifetime
- 2004-03-11 MX MXPA05009781A patent/MXPA05009781A/es active IP Right Grant
- 2004-03-11 PT PT04719589T patent/PT1604991E/pt unknown
- 2004-03-11 AT AT04719589T patent/ATE408408T1/de active
- 2004-03-11 ES ES04719589T patent/ES2312978T3/es not_active Expired - Lifetime
- 2004-03-11 DE DE602004016636T patent/DE602004016636D1/de not_active Expired - Lifetime
- 2004-03-11 PL PL04719589T patent/PL1604991T3/pl unknown
- 2004-03-11 WO PCT/JP2004/003189 patent/WO2004081012A1/ja active IP Right Grant
- 2004-03-11 AU AU2004220205A patent/AU2004220205B2/en not_active Ceased
- 2004-03-11 CN CNA2004800069779A patent/CN1761665A/zh active Pending
- 2004-03-11 CN CNA2008101445581A patent/CN101357134A/zh active Pending
- 2004-03-11 DK DK04719589T patent/DK1604991T3/da active
- 2004-03-11 RU RU2005131839/15A patent/RU2334517C2/ru active
- 2004-03-11 SI SI200430955T patent/SI1604991T1/sl unknown
- 2004-03-11 US US10/548,655 patent/US9611227B2/en active Active
- 2004-03-11 CA CA002518195A patent/CA2518195C/en not_active Expired - Fee Related
- 2004-03-11 JP JP2005503567A patent/JP4610481B2/ja not_active Expired - Lifetime
- 2004-03-11 KR KR1020057017150A patent/KR100812693B1/ko active IP Right Grant
- 2004-03-12 TW TW093106702A patent/TW200503720A/zh not_active IP Right Cessation
-
2008
- 2008-10-06 CY CY20081101101T patent/CY1108395T1/el unknown
-
2017
- 2017-02-17 US US15/435,493 patent/US9814724B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CN101357134A (zh) | 2009-02-04 |
| DE602004016636D1 (de) | 2008-10-30 |
| CY1108395T1 (el) | 2014-02-12 |
| JPWO2004081012A1 (ja) | 2006-06-08 |
| ATE408408T1 (de) | 2008-10-15 |
| US20060116345A1 (en) | 2006-06-01 |
| RU2005131839A (ru) | 2006-02-10 |
| SI1604991T1 (sl) | 2009-02-28 |
| CA2518195C (en) | 2009-07-07 |
| KR20050106119A (ko) | 2005-11-08 |
| PL1604991T3 (pl) | 2009-02-27 |
| BRPI0408372A (pt) | 2006-03-21 |
| JP4610481B2 (ja) | 2011-01-12 |
| CA2518195A1 (en) | 2004-09-23 |
| EP1604991A4 (de) | 2006-05-03 |
| AU2004220205B2 (en) | 2010-06-17 |
| AU2004220205A1 (en) | 2004-09-23 |
| KR100812693B1 (ko) | 2008-03-13 |
| NZ542150A (en) | 2009-09-25 |
| TWI295173B (de) | 2008-04-01 |
| EP1604991A1 (de) | 2005-12-14 |
| WO2004081012A1 (ja) | 2004-09-23 |
| MXPA05009781A (es) | 2005-10-26 |
| US20170157131A1 (en) | 2017-06-08 |
| US9814724B2 (en) | 2017-11-14 |
| US9611227B2 (en) | 2017-04-04 |
| ES2312978T3 (es) | 2009-03-01 |
| PT1604991E (pt) | 2008-10-27 |
| TW200503720A (en) | 2005-02-01 |
| CN1761665A (zh) | 2006-04-19 |
| EP1604991B1 (de) | 2008-09-17 |
| RU2334517C2 (ru) | 2008-09-27 |
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