DK159441C - 11-substituerede 5,11-dihydro-6h-dibenz(b,e)azepin-6-on-derivater, laegemidler indeholdende disse forbindelser og analogifremgangsmaade til forbindelsernes fremstilling - Google Patents

11-substituerede 5,11-dihydro-6h-dibenz(b,e)azepin-6-on-derivater, laegemidler indeholdende disse forbindelser og analogifremgangsmaade til forbindelsernes fremstilling

Info

Publication number
DK159441C
DK159441C DK021585A DK21585A DK159441C DK 159441 C DK159441 C DK 159441C DK 021585 A DK021585 A DK 021585A DK 21585 A DK21585 A DK 21585A DK 159441 C DK159441 C DK 159441C
Authority
DK
Denmark
Prior art keywords
compounds
dibenz
azepin
dihydro
substituted
Prior art date
Application number
DK021585A
Other languages
Danish (da)
English (en)
Other versions
DK21585D0 (da
DK21585A (da
DK159441B (da
Inventor
Wolfgang Eberlein
Guenter Trummlitz
Wolfhard Engel
Guenther Schmidt
Rudolf Hammer
Antonio Giachetti
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of DK21585D0 publication Critical patent/DK21585D0/da
Publication of DK21585A publication Critical patent/DK21585A/da
Publication of DK159441B publication Critical patent/DK159441B/da
Application granted granted Critical
Publication of DK159441C publication Critical patent/DK159441C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/18—Dibenzazepines; Hydrogenated dibenzazepines
    • C07D223/20—Dibenz [b, e] azepines; Hydrogenated dibenz [b, e] azepines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Pyrrole Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Hydrogenated Pyridines (AREA)
DK021585A 1984-01-21 1985-01-17 11-substituerede 5,11-dihydro-6h-dibenz(b,e)azepin-6-on-derivater, laegemidler indeholdende disse forbindelser og analogifremgangsmaade til forbindelsernes fremstilling DK159441C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3402060 1984-01-21
DE19843402060 DE3402060A1 (de) 1984-01-21 1984-01-21 Substituierte 5,11-dihydro-6h-dibenz(b,e)azepin-6-one, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel

Publications (4)

Publication Number Publication Date
DK21585D0 DK21585D0 (da) 1985-01-17
DK21585A DK21585A (da) 1985-07-22
DK159441B DK159441B (da) 1990-10-15
DK159441C true DK159441C (da) 1991-03-18

Family

ID=6225562

Family Applications (1)

Application Number Title Priority Date Filing Date
DK021585A DK159441C (da) 1984-01-21 1985-01-17 11-substituerede 5,11-dihydro-6h-dibenz(b,e)azepin-6-on-derivater, laegemidler indeholdende disse forbindelser og analogifremgangsmaade til forbindelsernes fremstilling

Country Status (24)

Country Link
US (1) US4567178A (no)
EP (1) EP0149840B1 (no)
JP (1) JPH0662575B2 (no)
KR (1) KR910006986B1 (no)
AT (1) ATE42553T1 (no)
AU (1) AU570761B2 (no)
CA (1) CA1241651A (no)
CS (1) CS247094B2 (no)
DD (1) DD235259A5 (no)
DE (2) DE3402060A1 (no)
DK (1) DK159441C (no)
ES (2) ES539668A0 (no)
FI (1) FI79534C (no)
GR (1) GR850131B (no)
HU (1) HU193250B (no)
IE (1) IE57754B1 (no)
IL (1) IL74101A (no)
NO (1) NO161619C (no)
NZ (1) NZ210875A (no)
PH (1) PH23209A (no)
PL (2) PL142866B1 (no)
PT (1) PT79837B (no)
SU (1) SU1308196A3 (no)
ZA (1) ZA85414B (no)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3531682A1 (de) * 1985-09-05 1987-03-12 Thomae Gmbh Dr K (+)-6-chlor-5,10-dihydro-5-((1-methyl-4- piperidinyl)acetyl)-11h-dibenzo(b,e)(1,4) diazepin-11-on, seine isolierung und verwendung als arzneimittel
IT8819192A0 (it) * 1988-01-25 1988-01-25 Angeli Inst Spa Amminochetoni di dibenzo e piridobenzo azepinoni sostituiti e composizioni farmaceutiche.
US5256699A (en) * 1988-10-18 1993-10-26 Ciba-Geify Corporation Dispersible tablet formulation of diclofenac acid free base
DE3838912A1 (de) * 1988-11-17 1990-05-23 Thomae Gmbh Dr K Mittel zur behandlung von akuten und chronischen obstruktiven atemwegserkrankungen
US6509346B2 (en) 1998-01-21 2003-01-21 Millennium Pharmaceuticals, Inc. Chemokine receptor antagonists and methods of use therefor
BR9910144A (pt) 1998-01-21 2002-04-02 Millennium Pharm Inc Antagonistas de receptores de quimiocinas e seu uso
US6433165B1 (en) * 1998-01-21 2002-08-13 Millennium Pharmaceuticals, Inc. Chemokine receptor antagonists and methods of use therefor
US6613905B1 (en) 1998-01-21 2003-09-02 Millennium Pharmaceuticals, Inc. Chemokine receptor antagonists and methods of use therefor
NZ505329A (en) * 1998-06-08 2003-05-30 Theravance Inc Two heteroaryl or aryl containing compounds covalently attached via a linker useful as muscarinic receptor antagonists
US7271176B2 (en) * 1998-09-04 2007-09-18 Millennium Pharmaceuticals, Inc. Chemokine receptor antagonists and methods of use thereof
US6693202B1 (en) * 1999-02-16 2004-02-17 Theravance, Inc. Muscarinic receptor antagonists
UA73543C2 (uk) 1999-12-07 2005-08-15 Тераванс, Інк. Похідні сечовини, фармацевтична композиція та застосування похідного при приготуванні лікарського засобу для лікування захворювання, яке опосередковується мускариновим рецептором
DE60021282T2 (de) 1999-12-07 2006-05-18 Theravance, Inc., South San Francisco Carbamat-derivate als muscarin-rezeptor antonisten
US7541365B2 (en) * 2001-11-21 2009-06-02 Millennium Pharmaceuticals, Inc. Chemokine receptor antagonists and methods of use therefor
TWI291467B (en) 2002-11-13 2007-12-21 Millennium Pharm Inc CCR1 antagonists and methods of use therefor

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1795176C3 (de) * 1968-08-20 1974-10-24 Dr. Karl Thomae Gmbh, 7950 Biberach hT-substituierte 5-Aminoacetyl-5,10-dihydro-l lH-dibenzo eckige Klammer auf b,e eckige Klammer zu eckige Klammer auf 1,4 eckige Klammer zu diazepin-11one und Verfahren zu ihrer Herstellung
CH624682A5 (no) * 1976-11-10 1981-08-14 Sandoz Ag
DE2918832A1 (de) * 1979-05-10 1980-11-20 Basf Ag 5,6-dihydro-11-alkylen-morphantridin- 6-one
DE3204157A1 (de) * 1982-02-06 1983-08-11 Dr. Karl Thomae Gmbh, 7950 Biberach Substituierte dibenzodiazepinone, verfahren zu ihrer herstellung und sie enthaltende arzneimittel

Also Published As

Publication number Publication date
PT79837A (en) 1985-02-01
DE3477927D1 (en) 1989-06-01
EP0149840B1 (de) 1989-04-26
NO161619B (no) 1989-05-29
PL255144A1 (en) 1986-08-12
SU1308196A3 (ru) 1987-04-30
PL142866B1 (en) 1987-12-31
PL142903B1 (en) 1987-12-31
NO161619C (no) 1989-09-06
IE57754B1 (en) 1993-03-24
FI850228L (fi) 1985-07-22
HUT37141A (en) 1985-11-28
CS247094B2 (en) 1986-11-13
GR850131B (no) 1985-05-17
ES8601908A1 (es) 1985-11-16
DK21585D0 (da) 1985-01-17
IE850117L (en) 1985-07-21
US4567178A (en) 1986-01-28
AU3779285A (en) 1985-08-01
DD235259A5 (de) 1986-04-30
DK21585A (da) 1985-07-22
PH23209A (en) 1989-06-06
NZ210875A (en) 1987-07-31
ZA85414B (en) 1986-09-24
IL74101A0 (en) 1985-04-30
FI850228A0 (fi) 1985-01-18
KR850005414A (ko) 1985-08-26
HU193250B (en) 1987-08-28
NO850216L (no) 1985-07-22
EP0149840A1 (de) 1985-07-31
PT79837B (en) 1986-12-18
ES8604524A1 (es) 1986-02-01
FI79534C (fi) 1990-01-10
ES545025A0 (es) 1986-02-01
DE3402060A1 (de) 1985-08-01
ES539668A0 (es) 1985-11-16
IL74101A (en) 1988-09-30
DK159441B (da) 1990-10-15
PL251603A1 (en) 1985-12-17
FI79534B (fi) 1989-09-29
JPH0662575B2 (ja) 1994-08-17
ATE42553T1 (de) 1989-05-15
JPS60161970A (ja) 1985-08-23
KR910006986B1 (ko) 1991-09-14
AU570761B2 (en) 1988-03-24
CA1241651A (en) 1988-09-06

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