DK157920C - Analogifremgangsmaade til fremstilling af indolderivater - Google Patents
Analogifremgangsmaade til fremstilling af indolderivaterInfo
- Publication number
- DK157920C DK157920C DK357081A DK357081A DK157920C DK 157920 C DK157920 C DK 157920C DK 357081 A DK357081 A DK 357081A DK 357081 A DK357081 A DK 357081A DK 157920 C DK157920 C DK 157920C
- Authority
- DK
- Denmark
- Prior art keywords
- incidental
- derivatives
- preparation
- analogy procedure
- analogy
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
- C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C243/00—Compounds containing chains of nitrogen atoms singly-bound to each other, e.g. hydrazines, triazanes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
- C07C251/72—Hydrazones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
- C07D209/16—Tryptamines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Cardiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB8026286 | 1980-08-12 | ||
| GB8026286 | 1980-08-12 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| DK357081A DK357081A (da) | 1982-02-13 |
| DK157920B DK157920B (da) | 1990-03-05 |
| DK157920C true DK157920C (da) | 1990-08-06 |
Family
ID=10515410
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK357081A DK157920C (da) | 1980-08-12 | 1981-08-11 | Analogifremgangsmaade til fremstilling af indolderivater |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US4650810A (es) |
| JP (1) | JPS5764669A (es) |
| AU (1) | AU548467B2 (es) |
| BE (1) | BE889929A (es) |
| CA (1) | CA1169428A (es) |
| CH (1) | CH651551A5 (es) |
| DE (1) | DE3131728A1 (es) |
| DK (1) | DK157920C (es) |
| ES (5) | ES8301210A1 (es) |
| FR (1) | FR2488607A1 (es) |
| IE (1) | IE51491B1 (es) |
| IT (1) | IT1171449B (es) |
| NL (1) | NL8103769A (es) |
| NZ (1) | NZ197996A (es) |
| SE (1) | SE454880B (es) |
| ZA (1) | ZA815540B (es) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1170387B (it) * | 1982-06-07 | 1987-06-03 | Glaxo Group Ltd | Composti eterociclici, procedimento per prepararli e composizioni farmaceutiche che li contengono |
| GB8332435D0 (en) * | 1983-12-06 | 1984-01-11 | Glaxo Group Ltd | Chemical compounds |
| GB8419575D0 (en) * | 1984-08-01 | 1984-09-05 | Glaxo Group Ltd | Chemical compounds |
| US4833153A (en) * | 1985-11-08 | 1989-05-23 | Glaxo Group Limited | Indole derivatives |
| GB8530507D0 (en) * | 1985-12-11 | 1986-01-22 | Glaxo Group Plc | Chemical compounds |
| US5270333A (en) * | 1986-01-28 | 1993-12-14 | Glaxo Group Limited | Indole derivatives |
| GB8607824D0 (en) * | 1986-03-27 | 1986-04-30 | Glaxo Group Ltd | Chemical compounds |
| HU219974B (hu) * | 1990-06-07 | 2001-10-28 | Astrazeneca Ab, | Heterociklusos csoporttal helyettesített indolszármazék, előállítása és a vegyületet hatóanyagként tartalmazó gyógyszerkészítmények |
| SK278998B6 (sk) * | 1991-02-01 | 1998-05-06 | Merck Sharp & Dohme Limited | Deriváty imidazolu, triazolu a tetrazolu, spôsob i |
| US5254383A (en) * | 1992-09-14 | 1993-10-19 | Allied-Signal Inc. | Composites having improved penetration resistance and articles fabricated from same |
| FR2701026B1 (fr) * | 1993-02-02 | 1995-03-31 | Adir | Nouveaux dérivés de l'indole, de l'indazole et du benzisoxazole, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent. |
| US5468768A (en) * | 1994-01-06 | 1995-11-21 | Bristol-Myers Squibb Company | Antimigraine derivatives of indolylcycloalkanylamines |
| ES2084560B1 (es) * | 1994-03-09 | 1997-01-16 | Almirall Lab | Procedimiento de preparacion de derivados el indol. |
| US5891885A (en) * | 1996-10-09 | 1999-04-06 | Algos Pharmaceutical Corporation | Method for treating migraine |
| US20030096379A1 (en) * | 2001-03-28 | 2003-05-22 | Kilgore James L. | Method for producing tryptamine derivatives |
| US6685951B2 (en) | 2001-07-05 | 2004-02-03 | R. T. Alamo Ventures I, Inc. | Administration of dihydroergotamine as a sublingual spray or aerosol for the treatment of migraine |
| US20030017175A1 (en) * | 2001-07-05 | 2003-01-23 | R.T. Alamo Ventures I, Inc. | Sublingual administration of dihydroergotamine for the treatment of migraine |
| US20030198669A1 (en) * | 2001-07-05 | 2003-10-23 | R.T. Alamo Ventures I, Llc | Compositions and methods for rapid dissolving formulations of dihydroergotamine and caffeine for the treatment of migraine |
| CN1729174B (zh) * | 2002-12-20 | 2015-10-21 | 西巴特殊化学品控股有限公司 | 胺的合成以及用于合成胺的中间体 |
| CA2677838C (en) * | 2007-02-11 | 2017-08-01 | Map Pharmaceuticals, Inc. | Method of therapeutic administration of dhe to enable rapid relief of migraine while minimizing side effect profile |
| CL2008000838A1 (es) * | 2007-03-23 | 2008-10-10 | Neuraxon Inc | Compuestos derivados de quinolina y tetrahidroquinolina, con actividad inhibidora nos; composicion farmaceutica que comprende a dichos compuestos; y su uso para tratar un dolor de cabeza tal como migrana, dolor cronico, desordenes del sistema nervios |
| AU2008233553A1 (en) | 2007-03-29 | 2008-10-09 | Daiichi Sankyo Company, Limited | Indole derivative having cPLA2 inhibitory activity, use of the same and method for producing the same |
| US20110171141A1 (en) * | 2009-06-26 | 2011-07-14 | Kellerman Donald J | Administration of dihydroergotamine mesylate particles using a metered dose inhaler |
| EP2734634B1 (en) | 2011-07-22 | 2019-08-21 | The University of Chicago | Igf-1 for use in the treatment of migraine |
| US9394314B2 (en) | 2012-12-21 | 2016-07-19 | Map Pharmaceuticals, Inc. | 8′-hydroxy-dihydroergotamine compounds and compositions |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3182071A (en) * | 1961-06-27 | 1965-05-04 | Warner Lambert Pharmaceutical | Acylated indole derivatives |
| US3472870A (en) * | 1966-08-29 | 1969-10-14 | Mead Johnson & Co | Sulfonamidotryptamines |
| ZA795239B (en) * | 1978-10-12 | 1980-11-26 | Glaxo Group Ltd | Heterocyclic compounds |
-
1981
- 1981-08-11 BE BE0/205642A patent/BE889929A/fr not_active IP Right Cessation
- 1981-08-11 ZA ZA815540A patent/ZA815540B/xx unknown
- 1981-08-11 FR FR8115513A patent/FR2488607A1/fr active Granted
- 1981-08-11 CH CH5159/81A patent/CH651551A5/fr not_active IP Right Cessation
- 1981-08-11 IT IT49084/81A patent/IT1171449B/it active
- 1981-08-11 NL NL8103769A patent/NL8103769A/nl not_active Application Discontinuation
- 1981-08-11 DE DE19813131728 patent/DE3131728A1/de active Granted
- 1981-08-11 DK DK357081A patent/DK157920C/da not_active IP Right Cessation
- 1981-08-11 SE SE8104781A patent/SE454880B/sv not_active IP Right Cessation
- 1981-08-11 IE IE1830/81A patent/IE51491B1/en unknown
- 1981-08-11 NZ NZ197996A patent/NZ197996A/en unknown
- 1981-08-11 ES ES504693A patent/ES8301210A1/es not_active Expired
- 1981-08-11 AU AU73994/81A patent/AU548467B2/en not_active Ceased
- 1981-08-12 CA CA000383670A patent/CA1169428A/en not_active Expired
- 1981-08-12 JP JP56125411A patent/JPS5764669A/ja active Granted
-
1982
- 1982-07-13 ES ES513933A patent/ES513933A0/es active Granted
-
1983
- 1983-01-26 US US06/461,233 patent/US4650810A/en not_active Expired - Fee Related
- 1983-03-18 ES ES520783A patent/ES8504706A1/es not_active Expired
- 1983-03-18 ES ES520784A patent/ES520784A0/es active Granted
- 1983-03-18 ES ES520785A patent/ES8500903A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| ZA815540B (en) | 1983-03-30 |
| DK157920B (da) | 1990-03-05 |
| AU548467B2 (en) | 1985-12-12 |
| ES8402268A1 (es) | 1984-01-16 |
| FR2488607B1 (es) | 1984-11-16 |
| ES520783A0 (es) | 1985-05-01 |
| FR2488607A1 (fr) | 1982-02-19 |
| DE3131728C2 (es) | 1992-04-30 |
| ES520785A0 (es) | 1984-11-01 |
| IE811830L (en) | 1982-02-12 |
| SE454880B (sv) | 1988-06-06 |
| ES504693A0 (es) | 1982-12-01 |
| CA1169428A (en) | 1984-06-19 |
| BE889929A (fr) | 1982-02-11 |
| ES8500903A1 (es) | 1984-11-01 |
| IT1171449B (it) | 1987-06-10 |
| NL8103769A (nl) | 1982-03-01 |
| DK357081A (da) | 1982-02-13 |
| ES8500902A1 (es) | 1984-11-01 |
| IE51491B1 (en) | 1987-01-07 |
| US4650810A (en) | 1987-03-17 |
| JPS5764669A (en) | 1982-04-19 |
| JPH0247462B2 (es) | 1990-10-19 |
| SE8104781L (sv) | 1982-02-13 |
| DE3131728A1 (de) | 1982-03-11 |
| AU7399481A (en) | 1982-02-18 |
| NZ197996A (en) | 1985-08-16 |
| IT8149084A0 (it) | 1981-08-11 |
| ES8504706A1 (es) | 1985-05-01 |
| CH651551A5 (fr) | 1985-09-30 |
| ES513933A0 (es) | 1984-01-16 |
| ES520784A0 (es) | 1984-11-01 |
| ES8301210A1 (es) | 1982-12-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PBP | Patent lapsed |