DK157787A - Zwitterioniske, bicykliske forbindelser og deres salte, solvater, hydrater og estere - Google Patents

Zwitterioniske, bicykliske forbindelser og deres salte, solvater, hydrater og estere

Info

Publication number
DK157787A
DK157787A DK157787A DK157787A DK157787A DK 157787 A DK157787 A DK 157787A DK 157787 A DK157787 A DK 157787A DK 157787 A DK157787 A DK 157787A DK 157787 A DK157787 A DK 157787A
Authority
DK
Denmark
Prior art keywords
esters
switterionic
solvates
hydrates
salts
Prior art date
Application number
DK157787A
Other languages
Danish (da)
English (en)
Other versions
DK157787D0 (da
Inventor
David John Blythin
Ho-Jane Shue
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of DK157787D0 publication Critical patent/DK157787D0/da
Publication of DK157787A publication Critical patent/DK157787A/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/36Sulfur atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D453/00Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Transplantation (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Steroid Compounds (AREA)
  • Professional, Industrial, Or Sporting Protective Garments (AREA)
  • Outer Garments And Coats (AREA)
DK157787A 1985-07-29 1987-03-27 Zwitterioniske, bicykliske forbindelser og deres salte, solvater, hydrater og estere DK157787A (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/760,196 US4684727A (en) 1985-07-29 1985-07-29 Zwitterionic 1,8-naphthyridine and pyrazino[2,3-b]pyridine containing compounds useful as anti-allergic, anti-inflammatory and cycloprotective agents
PCT/US1986/001518 WO1987000752A2 (en) 1985-07-29 1986-07-25 Zwitterionic bicyclic compounds and their salts, solvates, hydrates and esters

Publications (2)

Publication Number Publication Date
DK157787D0 DK157787D0 (da) 1987-03-27
DK157787A true DK157787A (da) 1987-03-27

Family

ID=25058394

Family Applications (1)

Application Number Title Priority Date Filing Date
DK157787A DK157787A (da) 1985-07-29 1987-03-27 Zwitterioniske, bicykliske forbindelser og deres salte, solvater, hydrater og estere

Country Status (23)

Country Link
US (4) US4684727A (es)
EP (1) EP0232328B1 (es)
JP (1) JPH0794455B2 (es)
KR (1) KR900003490B1 (es)
AT (1) ATE74756T1 (es)
AU (1) AU597587B2 (es)
CA (1) CA1263654A (es)
CZ (1) CZ413991A3 (es)
DE (1) DE3684903D1 (es)
DK (1) DK157787A (es)
FI (1) FI871345A (es)
HU (1) HU201550B (es)
IE (1) IE59298B1 (es)
IL (1) IL79556A (es)
MX (1) MX9203320A (es)
MY (1) MY101970A (es)
NO (1) NO166862C (es)
NZ (1) NZ217016A (es)
OA (1) OA08501A (es)
PH (1) PH23887A (es)
PT (1) PT83080B (es)
WO (1) WO1987000752A2 (es)
ZA (1) ZA865631B (es)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4684727A (en) * 1985-07-29 1987-08-04 Schering Corporation Zwitterionic 1,8-naphthyridine and pyrazino[2,3-b]pyridine containing compounds useful as anti-allergic, anti-inflammatory and cycloprotective agents
US5037826A (en) * 1986-10-15 1991-08-06 Schering Corporation 1-substituted naphthyridine and pyridopyrazine derivatives
US5045542A (en) * 1986-10-20 1991-09-03 Schering Corporation Immune suppression method employing aryl-substituted naphthyridine and pyridopyrazine derivatives
US5350755A (en) * 1986-12-05 1994-09-27 Schering Corporation Compounds and methods for treating hyperproliferative skin disease
CA1309658C (en) * 1986-12-05 1992-11-03 David J. Blythin Pharmaceutical compositions for treatment of hyperproliferate skin disease
US4897487A (en) * 1988-04-06 1990-01-30 Schering Corporation Process for preparing intermediates for pharmaceutically useful bicyclic compounds
JPH07116187B2 (ja) * 1987-07-22 1995-12-13 シェリング・コーポレーション 二環式化合物、それらを薬剤として使用すること、それらの製法、およびそれらの製造に有用な中間体
US5180823A (en) * 1988-04-06 1993-01-19 Schering Corporation Processes for preparing bicyclic compounds
US5079360A (en) * 1988-04-06 1992-01-07 Schering Corporation Processes for preparing bicyclic compounds and intermediates thereof
US5341575A (en) * 1989-11-01 1994-08-30 Chisum Finis L Apparatus to gather, display, and/or print vehicle chassis measurement data for accurate repair of collision damaged vehicles
US5175151A (en) * 1990-09-07 1992-12-29 Schering Corporation Antiviral compounds and antihypertensive compounds
ATE161252T1 (de) * 1990-09-07 1998-01-15 Schering Corp Antivirale und antihypertensive verbindungen
US5760034A (en) * 1990-11-30 1998-06-02 Schering Corporation Heterocyclic substituted naphthyridinones and methods and compositions employing them
GB9026389D0 (en) * 1990-12-05 1991-01-23 Merck Sharp & Dohme Therapeutic agents
US5179093A (en) * 1991-05-10 1993-01-12 Schering Corporation Quinoline-diones
JP2683783B2 (ja) * 1992-07-10 1997-12-03 雪印乳業株式会社 シェーグレン症候群治療剤
US7083777B1 (en) * 1999-04-02 2006-08-01 The Brigham And Women's Hospital, Inc. Immunomodulating polymers
SV2003000753A (es) 2000-12-05 2003-06-16 Brigham & Womens Hospital Uso de polisacaridos zwitterionicos para la especifica modulacion del progreso inmunologico
AU2004227852B2 (en) * 2003-03-31 2010-01-14 The Brigham And Women's Hospital, Inc. Zwitterionic immunomodulators for the treatment of asthma and allergy
US8206726B2 (en) 2006-02-06 2012-06-26 The Brigham And Women's Hospital, Inc. Zwitterionic polysaccharides for promotion of immune system maturation and health
EP2731617A4 (en) 2011-07-12 2015-07-01 Brigham & Womens Hospital LIPID-CONTAINING PSA COMPOSITIONS, METHODS OF ISOLATION AND METHODS OF USING SAME
US10857177B2 (en) 2015-08-19 2020-12-08 President And Fellows Of Harvard College Lipidated PSA compositions and methods
US11491181B2 (en) 2016-07-15 2022-11-08 President And Fellows Of Harvard College Glycolipid compositions and methods of use

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4264602A (en) * 1975-08-15 1981-04-28 Sandoz, Inc. 4-Hydroxy-3-nitro-pyrido[2,3-B]pyridine-2(1H)-ones
FR2469962A1 (fr) * 1979-11-21 1981-05-29 Vallourec Procede et dispositif pour la fabrication d'un tube d'acier sans soudure par laminage a chaud sur mandrin
EP0092786B1 (en) * 1982-04-26 1987-01-07 Schering Corporation 1,8-naphthyridine and 1,5,8-azanaphthyridine derivatives
US4452800A (en) * 1982-04-26 1984-06-05 Schering Corporation Salts of 3(n-butyl)-4-hydroxy-1-phenyl-1,8-naphthyridine-2(1H)-one and their use in treating chronic obstructive lung diseases
US4551463A (en) * 1982-11-03 1985-11-05 Schering Corporation Composition containing 1-phenyl-1,8-naphthridin-2(1H)-ones and a non-steroidal anti-inflammatory drug
US4628055A (en) * 1982-11-03 1986-12-09 Schering Corporation Method for treating allergic reactions and compositions therefore
US4684727A (en) * 1985-07-29 1987-08-04 Schering Corporation Zwitterionic 1,8-naphthyridine and pyrazino[2,3-b]pyridine containing compounds useful as anti-allergic, anti-inflammatory and cycloprotective agents

Also Published As

Publication number Publication date
NO871311L (no) 1987-03-27
US4794116A (en) 1988-12-27
WO1987000752A3 (en) 1987-05-21
US4782067A (en) 1988-11-01
PH23887A (en) 1989-12-18
CA1263654A (en) 1989-12-05
NO871311D0 (no) 1987-03-27
HUT42481A (en) 1987-07-28
DK157787D0 (da) 1987-03-27
WO1987000752A2 (en) 1987-02-12
ATE74756T1 (de) 1992-05-15
IL79556A (en) 1995-05-26
JPS63500453A (ja) 1988-02-18
NZ217016A (en) 1989-11-28
US4684727A (en) 1987-08-04
FI871345A0 (fi) 1987-03-27
EP0232328A1 (en) 1987-08-19
HU201550B (en) 1990-11-28
PT83080B (pt) 1989-01-30
NO166862C (no) 1991-09-11
PT83080A (en) 1986-08-01
FI871345A (fi) 1987-03-27
JPH0794455B2 (ja) 1995-10-11
EP0232328B1 (en) 1992-04-15
MX9203320A (es) 1992-07-01
DE3684903D1 (de) 1992-05-21
IE861997L (en) 1987-01-29
AU597587B2 (en) 1990-06-07
KR900003490B1 (ko) 1990-05-21
KR870700352A (ko) 1987-12-28
CZ413991A3 (en) 1993-01-13
MY101970A (en) 1992-02-29
OA08501A (en) 1988-07-29
NO166862B (no) 1991-06-03
US4902693A (en) 1990-02-20
IE59298B1 (en) 1994-02-09
AU6147986A (en) 1987-03-05
ZA865631B (en) 1987-03-25

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Legal Events

Date Code Title Description
AHB Application shelved due to non-payment
PBP Patent lapsed