DK1547615T3 - Lægemiddel - Google Patents
Lægemiddel Download PDFInfo
- Publication number
- DK1547615T3 DK1547615T3 DK03791347.2T DK03791347T DK1547615T3 DK 1547615 T3 DK1547615 T3 DK 1547615T3 DK 03791347 T DK03791347 T DK 03791347T DK 1547615 T3 DK1547615 T3 DK 1547615T3
- Authority
- DK
- Denmark
- Prior art keywords
- macrophages
- plga
- cells
- medicament
- macrophage
- Prior art date
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- A—HUMAN NECESSITIES
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- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
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- A—HUMAN NECESSITIES
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- A61P37/00—Drugs for immunological or allergic disorders
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- A—HUMAN NECESSITIES
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- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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- AIDS & HIV (AREA)
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- Pulmonology (AREA)
- Inorganic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
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- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
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Claims (7)
1. Medikament til anvendelse i en fremgangsmåde til behandling af en sygdom grundet en makrofag dysfunktion, hvilken sygdom er valgt fra mycobacteriose, AIDS, chlamydiose, tuberkulose, toxoplasmose, malaria, cancer, Crohn's sygdom og rheumatoid, hvilket medikament omfatter PLGA [poly(mælkesyre/glycolsyre)copolymer] med en molekylvægt på 5000 til 10.000, der forstærker den fagocytiske aktivitet af makrofagerne og tilintetgør alle eller en del af patogenerne til stede i makrofagerne.
2. Medikamentet til anvendelse ifølge krav 1, yderligere omfattende rifampicin.
3. Medikamentet til anvendelse ifølge krav 1 eller 2, yderligere omfattende mindst én af PVA (polyvinylalkohol), PEG (polyethylenglycol), PEO (polyethylenoxid), sukker, protein, peptid, phospholipid eller cholesterol.
4. Medikamentet til anvendelse ifølge krav 1 eller 2, yderligere omfattende mindst én af PVA (polyvinylalkohol), PEG (polyethylenglycol), PEO (polyethylenoxid), sukker, protein, peptid, phospholipid eller cholesterol, og er en fin partikelformulering hvor store partikeldiametre er 1 til 6 pm.
5. Medikamentet til anvendelse ifølge et hvilket som helst af kravene 1 til 4, fremstillet ved membran-emulsifikationsfremgangsmåden.
6. Medikament til behandling af lungecancer, hvilket medikament omfatter lipopolysaccharid af Pantoea agglomerans og har cytotoksisk virkning på lungecancerceller, der forstærker den fagocytiske aktivitet af makrofagerne og virker på makrofagerne i en dysfunktionel tilstand.
7. Medikamentet til anvendelse ifølge krav 6, hvor makrofagerne foreligger i slimhindevæv.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2002247871 | 2002-08-27 | ||
| PCT/JP2003/010871 WO2004019982A1 (ja) | 2002-08-27 | 2003-08-27 | 治療薬 |
Publications (1)
| Publication Number | Publication Date |
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| DK1547615T3 true DK1547615T3 (da) | 2016-06-06 |
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| US (4) | US20060105048A1 (da) |
| EP (2) | EP2343072A1 (da) |
| JP (1) | JP3947999B2 (da) |
| KR (3) | KR20110002877A (da) |
| CN (4) | CN1935156A (da) |
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| JP2007284362A (ja) * | 2006-04-13 | 2007-11-01 | Tokyo Univ Of Science | 薬物送達粒子及びその製造方法 |
| EA016540B1 (ru) * | 2008-12-30 | 2012-05-30 | Ооо "Научно-Производственный Комплекс "Наносистема" | Фармацевтическая композиция для лечения туберкулеза, способ ее получения и способ лечения туберкулеза |
| EP2489270A4 (en) * | 2009-09-28 | 2013-06-26 | Genichiro Soma | PLANT BREEDING AGENT, RESISTANCE INDUCTOR FOR PLANT HARVEST AND METHOD OF COMBATING PLANT HAZARD |
| US8802433B2 (en) | 2009-12-03 | 2014-08-12 | Aureo Co., Ltd. | Macrophage phagocytosis-activating composition and/or composition promoting cytokine production in macrophages |
| CN105530953A (zh) * | 2013-10-03 | 2016-04-27 | 日东电工株式会社 | 注射疫苗组合物 |
| WO2017097876A1 (en) * | 2015-12-08 | 2017-06-15 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods for expanding a population of alveolar macrophages in a long term culture |
| EP3660078A4 (en) * | 2017-07-27 | 2021-04-21 | Samyang Biopharmaceuticals Corporation | METHOD FOR MANUFACTURING BIO-DEGRADABLE POLYMER MICROPARTICLES AND BIO-DEGRADABLE POLYMER MICROPARTICLES SO MANUFACTURED |
| KR200490892Y1 (ko) | 2019-02-26 | 2020-01-17 | 주식회사 남현 | 체압 연동형 의자 등받이 경사 조절기구 |
| KR102210240B1 (ko) | 2020-01-15 | 2021-02-01 | 주식회사 남현 | 탄성력 조절이 가능한 의자 등받이 경사 조절기구 |
| JP7521876B1 (ja) | 2023-09-13 | 2024-07-24 | 源一郎 杣 | 抗老化用組成物、抗老化用製品、及びその製造方法 |
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|---|---|---|---|---|
| US1739064A (en) * | 1922-12-29 | 1929-12-10 | Ind Waste Products Corp | Process for the manufacture of a sugar product |
| EP0472467A3 (en) * | 1990-08-20 | 1993-03-17 | Chiba Flour Milling Co. Ltd. | Lps-containing analgesics and veterinary analgesics |
| US5759583A (en) * | 1995-08-30 | 1998-06-02 | Syntex (U.S.A.) Inc. | Sustained release poly (lactic/glycolic) matrices |
| US6126919A (en) * | 1997-02-07 | 2000-10-03 | 3M Innovative Properties Company | Biocompatible compounds for pharmaceutical drug delivery systems |
| KR100367144B1 (ko) * | 1997-07-02 | 2003-01-14 | 유로-셀티크 소시에떼 아노뉨 | 관절과 체강(ｂｏｄｙ ｓｐａｃｅ)내에서 연장된 마취 |
| JP4204085B2 (ja) * | 1997-10-08 | 2009-01-07 | オリジナル・イメージ株式会社 | マクロファージ活性化剤 |
| ATE317687T1 (de) * | 1998-11-18 | 2006-03-15 | Univ Florida | Methode zur herstellung von beschichteten partikeln und diese enthaltende pharmazeutische formulierungen |
| JP4580479B2 (ja) * | 1998-12-21 | 2010-11-10 | 株式会社林原生物化学研究所 | 抗ｈｉｖ感染症剤 |
| US6406745B1 (en) * | 1999-06-07 | 2002-06-18 | Nanosphere, Inc. | Methods for coating particles and particles produced thereby |
| JP2002247871A (ja) | 2001-02-15 | 2002-08-30 | Matsushita Electric Ind Co Ltd | モータ制御装置及びモータ制御方法 |
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2003
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- 2003-08-27 UA UAA200502820A patent/UA84276C2/uk unknown
- 2003-08-27 CN CNA2006101149254A patent/CN1935156A/zh active Pending
- 2003-08-27 HU HUE03791347A patent/HUE030275T2/en unknown
- 2003-08-27 CN CN2010101681488A patent/CN101862456B/zh not_active Expired - Fee Related
- 2003-08-27 US US10/525,964 patent/US20060105048A1/en not_active Abandoned
- 2003-08-27 ES ES03791347.2T patent/ES2575534T3/es not_active Expired - Lifetime
- 2003-08-27 PL PL397022A patent/PL397022A1/pl not_active Application Discontinuation
- 2003-08-27 EP EP11000496A patent/EP2343072A1/en not_active Withdrawn
- 2003-08-27 MX MXPA05002209A patent/MXPA05002209A/es active IP Right Grant
- 2003-08-27 PL PL03375585A patent/PL375585A1/xx not_active IP Right Cessation
- 2003-08-27 CN CNA200610114924XA patent/CN1935155A/zh active Pending
- 2003-08-27 WO PCT/JP2003/010871 patent/WO2004019982A1/ja active Application Filing
- 2003-08-27 BR BR0313881-0A patent/BR0313881A/pt not_active IP Right Cessation
- 2003-08-27 CN CNA038203278A patent/CN1678350A/zh active Pending
- 2003-08-27 CA CA2496902A patent/CA2496902C/en not_active Expired - Fee Related
- 2003-08-27 AU AU2003261768A patent/AU2003261768B2/en not_active Ceased
- 2003-08-27 EA EA200500418A patent/EA008107B1/ru not_active IP Right Cessation
- 2003-08-27 SG SG200700557-2A patent/SG151103A1/en unknown
- 2003-08-27 KR KR1020107026830A patent/KR20110002876A/ko not_active Application Discontinuation
- 2003-08-27 CA CA2706622A patent/CA2706622C/en not_active Expired - Fee Related
- 2003-08-27 EP EP03791347.2A patent/EP1547615B1/en not_active Expired - Lifetime
- 2003-08-27 DK DK03791347.2T patent/DK1547615T3/da active
- 2003-08-27 KR KR1020057003529A patent/KR101067971B1/ko not_active IP Right Cessation
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2005
- 2005-03-24 ZA ZA200502452A patent/ZA200502452B/en unknown
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2010
- 2010-03-22 US US12/659,796 patent/US8425939B2/en not_active Expired - Fee Related
- 2010-12-23 HK HK10112021.6A patent/HK1145463A1/xx not_active IP Right Cessation
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2013
- 2013-03-14 US US13/831,439 patent/US20130202663A1/en not_active Abandoned
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2014
- 2014-03-21 US US14/221,606 patent/US20140206641A1/en not_active Abandoned
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