DK154287A - Substituerede oxadiazol-derivater, fremgangsmaade til fremstilling deraf og mellemprodukter til brug ved fremgangsmaaden samt laegemiddel indeholdende oxadiazolerne - Google Patents

Substituerede oxadiazol-derivater, fremgangsmaade til fremstilling deraf og mellemprodukter til brug ved fremgangsmaaden samt laegemiddel indeholdende oxadiazolerne

Info

Publication number
DK154287A
DK154287A DK154287A DK154287A DK154287A DK 154287 A DK154287 A DK 154287A DK 154287 A DK154287 A DK 154287A DK 154287 A DK154287 A DK 154287A DK 154287 A DK154287 A DK 154287A
Authority
DK
Denmark
Prior art keywords
oxadiazoles
intermediates
procedures
procedure
production
Prior art date
Application number
DK154287A
Other languages
Danish (da)
English (en)
Other versions
DK154287D0 (da
Inventor
Raymond Baker
Angus Murray Macleod
Kevin John Merchant
John Saunders
Original Assignee
Merck Sharp & Dohme
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB868607713A external-priority patent/GB8607713D0/en
Priority claimed from GB868630896A external-priority patent/GB8630896D0/en
Application filed by Merck Sharp & Dohme filed Critical Merck Sharp & Dohme
Publication of DK154287D0 publication Critical patent/DK154287D0/da
Publication of DK154287A publication Critical patent/DK154287A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/52—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/06—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing isoquinuclidine ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08—Bridged systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08—Bridged systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
DK154287A 1986-03-27 1987-03-26 Substituerede oxadiazol-derivater, fremgangsmaade til fremstilling deraf og mellemprodukter til brug ved fremgangsmaaden samt laegemiddel indeholdende oxadiazolerne DK154287A (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB868607713A GB8607713D0 (en) 1986-03-27 1986-03-27 Oxadiazoles
GB868630896A GB8630896D0 (en) 1986-12-24 1986-12-24 Oxadiazoles

Publications (2)

Publication Number Publication Date
DK154287D0 DK154287D0 (da) 1987-03-26
DK154287A true DK154287A (da) 1987-09-28

Family

ID=26290549

Family Applications (1)

Application Number Title Priority Date Filing Date
DK154287A DK154287A (da) 1986-03-27 1987-03-26 Substituerede oxadiazol-derivater, fremgangsmaade til fremstilling deraf og mellemprodukter til brug ved fremgangsmaaden samt laegemiddel indeholdende oxadiazolerne

Country Status (16)

Country Link
US (1) US5686463A (de)
EP (1) EP0239309B1 (de)
JP (1) JPH0784466B2 (de)
KR (1) KR870008883A (de)
CN (1) CN87102972A (de)
AU (1) AU603564B2 (de)
DE (1) DE3788739T2 (de)
DK (1) DK154287A (de)
ES (1) ES2061489T3 (de)
FI (1) FI871325A (de)
HU (1) HUT51617A (de)
IL (1) IL81930A0 (de)
NO (1) NO169439C (de)
NZ (1) NZ219646A (de)
PT (1) PT84533B (de)
YU (1) YU46688B (de)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4837241A (en) * 1986-09-08 1989-06-06 A/S Ferrosan Lipophillically-substituted piperidine oxadiazolyl compounds and their use in stimulating cognitive functions
US5043345A (en) * 1989-02-22 1991-08-27 Novo Nordisk A/S Piperidine compounds and their preparation and use

Families Citing this family (74)

* Cited by examiner, † Cited by third party
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GB8528633D0 (en) * 1985-11-21 1985-12-24 Beecham Group Plc Compounds
GB8615785D0 (en) * 1986-06-27 1986-08-06 Beecham Group Plc Compounds
DE3789039T2 (de) * 1986-06-27 1994-06-09 Beecham Group Plc Verbrückte bicyclische N-heterocyclische Verbindungen.
AU620783B3 (en) * 1986-06-27 1992-01-09 Beecham Group Plc 1,2,4-oxadiazolyl-azabicyclo compounds
AU614513B2 (en) * 1987-04-15 1991-09-05 Beecham Group Plc 1-azabicyclic compounds
GB8714789D0 (en) * 1987-06-24 1987-07-29 Lundbeck & Co As H Heterocyclic compounds
GB8717446D0 (en) * 1987-07-23 1987-08-26 Merck Sharp & Dohme Chemical compounds
EP0307141B1 (de) * 1987-09-10 1993-01-13 MERCK SHARP &amp; DOHME LTD. Oxazole und Thiazole zur Behandlung seniler Demenz
US5405853A (en) * 1987-09-10 1995-04-11 Merck Sharpe & Dohme Ltd. Thiadiazoles useful in the treatment of senile dementia
NZ226000A (en) * 1987-09-10 1991-06-25 Merck Sharp & Dohme Oxadiazolyl-azabicycloheptanes and pharmaceutical compositions
NZ225999A (en) * 1987-09-10 1992-04-28 Merck Sharp & Dohme Azacyclic- or azabicyclic-substituted thiadiazole derivatives and pharmaceutical compositions
IE63906B1 (en) * 1987-11-13 1995-06-14 Novo Nordisk As Azabicyclic compounds and their preparation and use
EP0322034A3 (de) * 1987-12-22 1991-01-02 Merck Sharp & Dohme Ltd. Methyltetrahydropyridyloxadiazole
EP0322182A3 (de) * 1987-12-22 1992-01-02 Beecham Group Plc Azabicyclische-Verbindungen, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zubereitungen
IL88846A0 (en) * 1988-01-08 1989-07-31 Merck Sharp & Dohme Lipophilic oxadiazoles,their preparation and pharmaceutical compositions containing them
NZ227684A (en) * 1988-01-30 1991-07-26 Merck Sharp & Dohme Pyrazine, pyridazine, and pyrimidine derivatives and pharmaceutical compositions
NZ227841A (en) * 1988-02-12 1991-08-27 Merck Sharp & Dohme Heterocyclic compounds with at least two non-condensed five membered rings and pharmaceutical compositions
GB8808433D0 (en) * 1988-04-11 1988-05-11 Merck Sharp & Dohme Therapeutic agents
GB8808926D0 (en) * 1988-04-15 1988-05-18 Beecham Group Plc Novel compounds
DK162892C (da) * 1988-07-04 1992-05-11 Novo Nordisk As 1,2,5,6-tetrahydropyridinforbindelser, deres fremstilling og farmaceutiske praeparater indeholdende disse
GB8816299D0 (en) * 1988-07-08 1988-08-10 Merck Sharp & Dohme Therapeutic agents
EP0363085A3 (de) * 1988-10-03 1991-03-27 Beecham Group Plc Chemische Verbindungen
CA2000041A1 (en) * 1988-10-13 1990-04-13 Barry S. Orlek Compounds
GB8830226D0 (en) * 1988-12-23 1989-02-22 Beecham Group Plc Novel compounds
IT1229491B (it) * 1988-12-28 1991-09-03 Roussel Maestretti S P A Ora R Derivati della 1,2,5,6-tetraidropiridina, loro procedimento di preparazione e loro impiego come sostanze medicinali
GB8911080D0 (en) * 1989-05-15 1989-06-28 Merck Sharp & Dohme Chemical process
US5106853A (en) * 1989-05-15 1992-04-21 Merck Sharp & Dohme, Ltd. Oxadiazole and its salts, their use in treating dementia
US5075317A (en) * 1989-06-21 1991-12-24 Fisons Corporation Spirofurane derivatives
EP0412798A3 (en) * 1989-08-08 1992-07-01 Merck Sharp & Dohme Ltd. Substituted pyridines, their preparation, formulations and use in dementia
US5177084A (en) * 1989-08-08 1993-01-05 Merck Sharp & Dohme Ltd. Therapeutic use of substituted benzenes, formulations thereof and novel substituted benzenes
GB8918061D0 (en) * 1989-08-08 1989-09-20 Merck Sharp & Dohme Therapeutic agents
GB8918060D0 (en) * 1989-08-08 1989-09-20 Merck Sharp & Dohme Therapeutic agents
EP0413545B1 (de) * 1989-08-16 1997-05-14 Beecham Group Plc Azabicyclische Verbindungen
ATE136031T1 (de) * 1989-10-07 1996-04-15 Beecham Group Plc Azabizyklische verbindungen, verfahren und zwischenprodukte zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungen
US5407938A (en) * 1990-04-10 1995-04-18 Israel Institute For Biological Research Certain 1-methyl-piperidine-4-spiro-4'-(1'-3'-oxazolines) and corresponding -(1',3' thiazolines)
EP0456310A3 (en) * 1990-05-09 1992-03-04 Merck Sharp & Dohme Ltd. Enantioselective synthesis of 3-substituted 1-azabicyclo (2.2.1)heptanes
DE69102816T2 (de) * 1990-05-11 1995-03-16 Sankyo Co Piperdinyloxy- und Chinindidinyloxy- isoxazol- Derivate, ihre Herstellung und ihre therapeutische Verwendung.
EP0459568A3 (en) * 1990-05-31 1992-09-30 Merck Sharp & Dohme Ltd. Substituted oxadiazoles and thiadiazoles for use in the treatment of glaucoma and novel compounds having such use
IE912760A1 (en) * 1990-08-06 1992-02-12 Smith Kline French Lab Compounds
DK198390D0 (da) * 1990-08-21 1990-08-21 Novo Nordisk As Heterocykliske forbindelser, deres fremstilling og anvendelse
USRE35822E (en) * 1990-08-21 1998-06-09 Novo Nordisk A/S Heterocyclic compounds
DK198590D0 (da) * 1990-08-21 1990-08-21 Novo Nordisk As Heterocykliske forbindelser, deres fremstilling og anvendelse
US5376668A (en) * 1990-08-21 1994-12-27 Novo Nordisk A/S Heterocyclic compounds
DK198490D0 (da) * 1990-08-21 1990-08-21 Novo Nordisk As Heterocykliske forbindelser, deres fremstilling og anvendelse
US5527813A (en) * 1990-08-21 1996-06-18 Novo Nordisk A/S Heterocyclic compounds and their preparation and use
US5418240A (en) * 1990-08-21 1995-05-23 Novo Nordisk A/S Heterocyclic compounds and their preparation and use
CA2050264A1 (en) * 1990-08-30 1992-03-01 Raymond Baker Substituted pyrazine and its salts, compositions containing them and their use in medicine
US5124460A (en) * 1991-05-06 1992-06-23 Merck Sharp & Dohme Ltd. Enantioselective synthesis of 3-substituted 1-azabicyclo (2.2.1)heptanes
IE922270A1 (en) * 1991-07-26 1993-01-27 Akzo Nv Pyrazole derivatives
US5641791A (en) * 1991-08-13 1997-06-24 Novo Nordisk A.S Heterocyclic compounds and their preparation and use
CA2126976A1 (en) * 1991-12-31 1993-07-08 Hisashi Takasugi Oxadiazole derivatives having acetylcholinesterase-inhibitory and muscarinic agonist activity
WO1993014089A1 (en) * 1992-01-13 1993-07-22 Novo Nordisk A/S Heterocyclic compounds and their preparation and use
US5244906A (en) * 1992-01-23 1993-09-14 Dowelanco Insect control with substituted oxadiazole and thiadiazole compounds
TW214545B (de) * 1992-02-17 1993-10-11 Ciba Geigy Ag
AU671163B2 (en) * 1992-12-23 1996-08-15 Neurosearch A/S Alkyl substituted heterocyclic compounds
AU672052B2 (en) * 1992-12-23 1996-09-19 Neurosearch A/S Antidepressant and antiparkinsonian compounds
AU672644B2 (en) * 1992-12-23 1996-10-10 Neurosearch A/S Aryl substituted heterocyclic compounds
US5393767A (en) * 1993-08-26 1995-02-28 Dowelanco Insect control with substituted triazole and tetrazole compounds
US5612351A (en) * 1994-11-08 1997-03-18 Novo Nordisk A/S Method of treating urinary bladder dysfunctions
GB9507203D0 (en) * 1995-04-07 1995-05-31 Smithkline Beecham Plc Novel compounds
JP2000501097A (ja) * 1995-11-29 2000-02-02 イーライ・リリー・アンド・カンパニー ヘテロ環式化合物およびそれらの使用
US5889019A (en) * 1995-11-29 1999-03-30 Eli Lilly And Company Heterocyclic compounds and their use
GB9603755D0 (en) * 1996-02-22 1996-04-24 Pfizer Ltd Therapeutic agents
US5834458A (en) * 1996-10-09 1998-11-10 Eli Lilly And Company Heterocyclic compounds and their use
US5733912A (en) * 1997-02-19 1998-03-31 Abbott Laboratories 7A-heterocycle substituted hexahydro-1H-pyrrolizine compounds useful in controlling chemical synaptic transmission
US6107313A (en) * 1998-10-02 2000-08-22 Combichem, Inc. Dopamine receptor antagonists
CA2420235A1 (en) * 2000-08-21 2002-02-28 Georgetown University 2-3-disubstituted quinuclidines as modulators of monoamine transporters and therapeutic and diagnostic methods based thereon
US7332508B2 (en) * 2002-12-18 2008-02-19 Novo Nordisk A/S Substituted homopiperidine, piperidine or pyrrolidine derivatives
JP4702051B2 (ja) 2003-03-05 2011-06-15 東レ株式会社 芳香族高分子、フィルム、電解質膜およびセパレーター
AU2004282201A1 (en) * 2003-10-15 2005-04-28 Targacept, Inc. Azabicycyclic compounds for relieving pain and treating central nervous system disorders
US8084473B2 (en) 2007-04-24 2011-12-27 Solvay Pharmaceuticals B.V. Heterocyclic compounds with affinity to muscarinic receptors
EP2296471A4 (de) 2008-05-15 2012-03-14 Univ Toledo Muskarinsäureagonisten als kognitive enhancer
KR102074089B1 (ko) * 2009-12-04 2020-02-05 선오비온 파마슈티컬스 인코포레이티드 다환형 화합물 및 이의 사용 방법
WO2012149524A1 (en) 2011-04-29 2012-11-01 The University Of Toledo Muscarinic agonists as enhancers of working memory and cognitive flexibility

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JPS5811948Y2 (ja) * 1982-02-25 1983-03-07 日清紡績株式会社 ブレ−キシユ−引込用スプリング装置
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IL83275A (en) * 1986-09-08 1994-02-27 Novo Nordisk As Compounds 1,2, 4-Oxadiazolyl Pipridine Transformed, their preparation and pharmaceutical preparations containing them
AU614513B2 (en) * 1987-04-15 1991-09-05 Beecham Group Plc 1-azabicyclic compounds
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EP0413545B1 (de) * 1989-08-16 1997-05-14 Beecham Group Plc Azabicyclische Verbindungen

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4837241A (en) * 1986-09-08 1989-06-06 A/S Ferrosan Lipophillically-substituted piperidine oxadiazolyl compounds and their use in stimulating cognitive functions
US4933353A (en) * 1986-09-08 1990-06-12 A/S Ferrosan Lipophilically-substituted piperidine oxadiazolyl compounds and their use in stimulating cognitive functions (II)
US5043345A (en) * 1989-02-22 1991-08-27 Novo Nordisk A/S Piperidine compounds and their preparation and use

Also Published As

Publication number Publication date
YU46688B (sh) 1994-04-05
DE3788739D1 (de) 1994-02-24
NO871277D0 (no) 1987-03-26
EP0239309B1 (de) 1994-01-12
FI871325A0 (fi) 1987-03-26
EP0239309A2 (de) 1987-09-30
NO169439B (no) 1992-03-16
HUT51617A (en) 1990-05-28
CN87102972A (zh) 1987-11-18
PT84533B (pt) 1989-11-10
JPH0784466B2 (ja) 1995-09-13
US5686463A (en) 1997-11-11
IL81930A0 (en) 1987-10-20
AU603564B2 (en) 1990-11-22
ES2061489T3 (es) 1994-12-16
NO169439C (no) 1992-06-24
EP0239309A3 (en) 1988-11-30
FI871325A (fi) 1987-09-28
AU7068687A (en) 1987-10-01
YU53587A (en) 1988-08-31
NO871277L (no) 1987-09-28
PT84533A (en) 1987-04-01
NZ219646A (en) 1990-10-26
DE3788739T2 (de) 1994-07-14
KR870008883A (ko) 1987-10-21
DK154287D0 (da) 1987-03-26
JPS6317879A (ja) 1988-01-25

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