DK1537122T3 - Antidepressive indolalkylderivater af heterocyclus-kondenserede benzodioxanmathylaminer - Google Patents
Antidepressive indolalkylderivater af heterocyclus-kondenserede benzodioxanmathylaminerInfo
- Publication number
- DK1537122T3 DK1537122T3 DK03754498T DK03754498T DK1537122T3 DK 1537122 T3 DK1537122 T3 DK 1537122T3 DK 03754498 T DK03754498 T DK 03754498T DK 03754498 T DK03754498 T DK 03754498T DK 1537122 T3 DK1537122 T3 DK 1537122T3
- Authority
- DK
- Denmark
- Prior art keywords
- disorder
- methylamines
- benzodioxane
- antidepressant
- heterocycle
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Addiction (AREA)
- Pain & Pain Management (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Cardiology (AREA)
- Child & Adolescent Psychology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Gynecology & Obstetrics (AREA)
- Heart & Thoracic Surgery (AREA)
- Psychology (AREA)
- Nutrition Science (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Indole Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Cosmetics (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US41034702P | 2002-09-12 | 2002-09-12 | |
| US10/659,238 US6800637B2 (en) | 2002-09-12 | 2003-09-10 | Antidepressant indolealkyl derivatives of heterocycle-fused benzodioxan methylamines |
| PCT/US2003/028524 WO2004024734A1 (en) | 2002-09-12 | 2003-09-11 | Antidepressant indolealkyl derivatives of heterocycle-fused benzodioxan methylamines |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1537122T3 true DK1537122T3 (da) | 2007-12-27 |
Family
ID=32717176
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK03754498T DK1537122T3 (da) | 2002-09-12 | 2003-09-11 | Antidepressive indolalkylderivater af heterocyclus-kondenserede benzodioxanmathylaminer |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US6800637B2 (da) |
| EP (1) | EP1537122B9 (da) |
| JP (1) | JP2006510595A (da) |
| KR (1) | KR20050042176A (da) |
| CN (1) | CN100358898C (da) |
| AT (1) | ATE370953T1 (da) |
| AU (1) | AU2003272322A1 (da) |
| BR (1) | BR0314513A (da) |
| CA (1) | CA2497214A1 (da) |
| DE (1) | DE60315843T2 (da) |
| DK (1) | DK1537122T3 (da) |
| EC (1) | ECSP055660A (da) |
| ES (1) | ES2291673T3 (da) |
| MX (1) | MXPA05002840A (da) |
| NO (1) | NO20051768D0 (da) |
| RU (1) | RU2005107587A (da) |
| WO (1) | WO2004024734A1 (da) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006089053A2 (en) * | 2005-02-17 | 2006-08-24 | Wyeth | Cycloalkylfused indole, benzothiophene, benzofuran and indene derivatives |
| US20080139546A1 (en) * | 2006-09-29 | 2008-06-12 | Wyeth | Tetrahydroquinoline, indoline, and related aniline derivatives of heterocycle-fused benzodioxan methylamines |
| WO2008118935A1 (en) * | 2007-03-26 | 2008-10-02 | Neurogen Corporation | Compounds and processes for preparing substituted aminomethyl-2,3,8,9-tetrahydro-7h-1,4-dioxino[2,3-e]indol-8-ones |
| AR066760A1 (es) * | 2007-05-30 | 2009-09-09 | Wyeth Corp | Derivados heteroarilo de benzodioxanos heterociclo-fusionados antidepresivos, composiciones farmaceuticas, procesos de obtencion |
| JP2012528120A (ja) * | 2009-05-27 | 2012-11-12 | ユニヴェルシテ リブル ドゥ ブリュッセル | ミエロペルオキシダーゼ阻害３−アルキル−５−フルオロインドール誘導体 |
| EP2459533A4 (en) | 2009-07-30 | 2013-01-16 | Univ Singapore | SMALL MOLECULE INHIBITORS OF ISOPRENYLCYSTEIN CARBOXYL METHYLTRANERASE WITH POTENTIAL ANTICANCING ACTIVITY |
| US8623324B2 (en) | 2010-07-21 | 2014-01-07 | Aat Bioquest Inc. | Luminescent dyes with a water-soluble intramolecular bridge and their biological conjugates |
| EP2481740B1 (en) * | 2011-01-26 | 2015-11-04 | DemeRx, Inc. | Methods and compositions for preparing noribogaine from voacangine |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2043709C (en) | 1990-06-29 | 2002-01-22 | David W. Smith | Antimigraine alkoxypyrimidine derivatives |
| GB9318431D0 (en) * | 1993-09-06 | 1993-10-20 | Boots Co Plc | Therapeutic agents |
| AR004229A1 (es) * | 1995-11-06 | 1998-11-04 | Wyeth Corp | Derivados indolalquilo de benzodioxanmetilamina y su uso para preparar medicamentos |
| US5756532A (en) * | 1995-11-06 | 1998-05-26 | American Home Products Corporation | Aminomethyl-2 3 8 9-tetrahydro-7H-1 4-dioxino 2 3-E!-indol-8-ones and derivatives |
| US5869490A (en) * | 1996-10-15 | 1999-02-09 | American Home Products Corporation | Azaheterocyclymethyl derivatives of 2,3,8,9-tetrahydro-7h-1,4-dioxino (2,3-e) indol-8-one |
| GB9704948D0 (en) * | 1997-03-11 | 1997-04-30 | Knoll Ag | Therapeutic agents |
| DE19858340A1 (de) | 1998-12-17 | 2000-06-21 | Merck Patent Gmbh | Verfahren zur Herstellung von 3-Alkanoyl- und 3-Alkylindolen |
| US6458802B1 (en) * | 2001-03-14 | 2002-10-01 | Wyeth | Antidepressant azaheterocyclymethyl derivatives of 2,3-dihydro-1,4-dioxino [2,3-f]quinoline |
| US6800648B2 (en) | 2001-04-26 | 2004-10-05 | Wyeth | Antipsychotic aminomethyl derivatives of 7,8-dihydro-3H-1,6,9-trioxa-3-AZA-cyclopenta[a]naphthalen-2-one |
| EP1392700B1 (en) * | 2001-04-30 | 2004-09-29 | Wyeth | Antidepressant azaheterocyclylmethyl derivatives of 7,8-dihydro-1,6,9-trioxa-3-aza-cyclopenta(a)naphthalene |
| AU2002309769B2 (en) * | 2001-05-17 | 2008-04-17 | Wyeth | Processes for the synthesis of derivatives of 2,3-dihydro-1,4-dioxino-[2,3-f] quinoline |
-
2003
- 2003-09-10 US US10/659,238 patent/US6800637B2/en not_active Expired - Fee Related
- 2003-09-11 DE DE60315843T patent/DE60315843T2/de not_active Expired - Fee Related
- 2003-09-11 CN CNB038214709A patent/CN100358898C/zh not_active Expired - Fee Related
- 2003-09-11 AU AU2003272322A patent/AU2003272322A1/en not_active Abandoned
- 2003-09-11 AT AT03754498T patent/ATE370953T1/de not_active IP Right Cessation
- 2003-09-11 DK DK03754498T patent/DK1537122T3/da active
- 2003-09-11 BR BR0314513-1A patent/BR0314513A/pt not_active IP Right Cessation
- 2003-09-11 WO PCT/US2003/028524 patent/WO2004024734A1/en active IP Right Grant
- 2003-09-11 ES ES03754498T patent/ES2291673T3/es not_active Expired - Lifetime
- 2003-09-11 CA CA002497214A patent/CA2497214A1/en not_active Abandoned
- 2003-09-11 EP EP03754498A patent/EP1537122B9/en not_active Expired - Lifetime
- 2003-09-11 JP JP2004536507A patent/JP2006510595A/ja active Pending
- 2003-09-11 MX MXPA05002840A patent/MXPA05002840A/es active IP Right Grant
- 2003-09-11 KR KR1020057003957A patent/KR20050042176A/ko not_active Application Discontinuation
- 2003-09-11 RU RU2005107587/04A patent/RU2005107587A/ru not_active Application Discontinuation
-
2005
- 2005-03-10 EC EC2005005660A patent/ECSP055660A/es unknown
- 2005-04-11 NO NO20051768A patent/NO20051768D0/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| AU2003272322A1 (en) | 2004-04-30 |
| CN100358898C (zh) | 2008-01-02 |
| DE60315843D1 (de) | 2007-10-04 |
| ATE370953T1 (de) | 2007-09-15 |
| RU2005107587A (ru) | 2006-01-20 |
| US20040138222A1 (en) | 2004-07-15 |
| CA2497214A1 (en) | 2004-03-25 |
| MXPA05002840A (es) | 2005-08-16 |
| NO20051768L (no) | 2005-04-11 |
| EP1537122B9 (en) | 2007-10-31 |
| JP2006510595A (ja) | 2006-03-30 |
| EP1537122B1 (en) | 2007-08-22 |
| ES2291673T3 (es) | 2008-03-01 |
| DE60315843T2 (de) | 2008-05-15 |
| KR20050042176A (ko) | 2005-05-04 |
| EP1537122A1 (en) | 2005-06-08 |
| BR0314513A (pt) | 2005-08-09 |
| CN1701075A (zh) | 2005-11-23 |
| ECSP055660A (es) | 2005-07-06 |
| WO2004024734A1 (en) | 2004-03-25 |
| US6800637B2 (en) | 2004-10-05 |
| NO20051768D0 (no) | 2005-04-11 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| NO20051768D0 (no) | Antidepressive indolalkylderivater av heterocykliske, kondenserte benzodioksanmetylaminer | |
| NO20051769L (no) | Antidepressivt virkende azaheterocykylmetylderivater av heterocykluskondenserte benzodioksaner | |
| ECSP055659A (es) | Derivados de cicloalquilamina antidepresiva de benzodioxanos fusionados con heterociclos | |
| DE60201829D1 (de) | Azaheterocyclylmethyl derivative des 2,3-dihydro-1,4-dioxino(2,3-f)quinolins als antidepressiva | |
| CO6220910A2 (es) | Proceso para la producir compuestos pesticidas de benzamidas | |
| BRPI0516735A (pt) | esquema de sìntese melhorada para lacosamida | |
| NO20055208L (no) | 4-(2-fenylsulfanyl-fenyl)-piperidinderivater som serotonin-reopptaksinhibitorer | |
| EA200600049A1 (ru) | Способы получения 3 - бензазепинов | |
| EA200701588A1 (ru) | Способы получения замещённых фенилпиразолмочевин | |
| DK1720823T3 (da) | Ny fremgangsmåde til syntese af substituerede alpha-amino-indanderivater | |
| BR0314277A (pt) | Composto; método de tratamento de um indivìduo acometido por uma condição de depressão, ansiedade, distúrbios do pânico, de tensão pós-traumática, disfórico pré-menstrual, de deficiência da atenção, obsessivos-compulsivos e alimentares, obesidade, rubor vasomotor, dependência de álcool e cocaìna e disfunção sexual; composição farmacêutica e uso do mesmo | |
| DE502004011239D1 (de) | Verfahren zur dehydratisierung substituierter 4-dimethylamino-2-aryl-butan-2-ol-verbindungen und verfahren zur herstellung substituierter dimethyl-(3-katalyse | |
| NO20076344L (no) | Piperazin-piperidin-antagonister og agonister av 5-HT1A-reseptoren | |
| NO20051617L (no) | Piperidinderivater av heterocyklusfusjonerte benzodioksaner med antidepressiv aktivitet | |
| AR035083A1 (es) | Derivados azaheterociclilmetilicos de 7,8-dihidro-6h-5-oxa-1-aza-fenantreno, composiciones farmaceuticas, el uso de dichos derivados para la preparacion de un medicamento antidepresivo e intermediarios | |
| WO2002088136A3 (en) | Antidepressant azaheterocyclylmethyl derivatives of 1,4,5-trioxa-phenanthrene | |
| ECSP088360A (es) | Métodos para preparar derivados de ácido glutámico | |
| ATE402136T1 (de) | Verfahren zur herstellung von aminoalkoxybenzylaminen und aminoalkoxybenzonitrilen als zwischenprodukte | |
| CR7723A (es) | Derivados de azaheterociclilmetilo de benzodioxanos fusionados con heterociclos antidepresivos | |
| BRPI0514313A (pt) | processo para sintetizar um composto, e, composto | |
| AR048134A1 (es) | La combinacion de un inhibidor de la recaptacion de serotonina y un antagonista del receptor de la histamina 3, el agonista inverso o el agonista parcial | |
| TH127131B (th) | กระบวนการเตรียมสารประกอบที่มีความว่องไวต่อปฏิกิริยาทางแสงโดยใช้ การไฮโดรจีเนชันแบบถ่ายเท | |
| ECSP066998A (es) | Derivados quirales de heptina para la preparación de epotilonas y procesos para prepararlos | |
| AR039723A1 (es) | Terapia de combinacion en donde se utiliza un inhibidor de recaptacion de serotonina |