DK153490A - Fremgangsmaade til oprensning af k-vitaminafhaengige blodkoagulationsfaktorer - Google Patents

Fremgangsmaade til oprensning af k-vitaminafhaengige blodkoagulationsfaktorer Download PDF

Info

Publication number
DK153490A
DK153490A DK153490A DK153490A DK153490A DK 153490 A DK153490 A DK 153490A DK 153490 A DK153490 A DK 153490A DK 153490 A DK153490 A DK 153490A DK 153490 A DK153490 A DK 153490A
Authority
DK
Denmark
Prior art keywords
vitamine
purification
procedure
blood coagulation
coagulation factors
Prior art date
Application number
DK153490A
Other languages
English (en)
Other versions
DK153490D0 (da
DK175514B1 (da
Inventor
Peter Anthony Feldman
Original Assignee
Central Blood Lab Authority
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Central Blood Lab Authority filed Critical Central Blood Lab Authority
Publication of DK153490A publication Critical patent/DK153490A/da
Publication of DK153490D0 publication Critical patent/DK153490D0/da
Application granted granted Critical
Publication of DK175514B1 publication Critical patent/DK175514B1/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/647—Blood coagulation factors not provided for in a preceding group or according to more than one of the proceeding groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Cooling, Air Intake And Gas Exhaust, And Fuel Tank Arrangements In Propulsion Units (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • External Artificial Organs (AREA)
DK199001534A 1987-12-22 1990-06-22 Fremgangsmåde til oprensning af K-vitaminafhængige blodkoagulationsfaktorer DK175514B1 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB8729822 1987-12-22
GB878729822A GB8729822D0 (en) 1987-12-22 1987-12-22 Chemical process
PCT/GB1988/001150 WO1989005650A2 (en) 1987-12-22 1988-12-22 Chemical process
GB8801150 1988-12-22

Publications (3)

Publication Number Publication Date
DK153490A true DK153490A (da) 1990-06-22
DK153490D0 DK153490D0 (da) 1990-06-22
DK175514B1 DK175514B1 (da) 2004-11-15

Family

ID=10628844

Family Applications (1)

Application Number Title Priority Date Filing Date
DK199001534A DK175514B1 (da) 1987-12-22 1990-06-22 Fremgangsmåde til oprensning af K-vitaminafhængige blodkoagulationsfaktorer

Country Status (9)

Country Link
EP (1) EP0391974B1 (da)
JP (1) JPH0664B2 (da)
AT (1) ATE90567T1 (da)
AU (1) AU627446B2 (da)
DE (1) DE3881895T2 (da)
DK (1) DK175514B1 (da)
GB (1) GB8729822D0 (da)
NO (1) NO178882C (da)
WO (1) WO1989005650A2 (da)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT402262B (de) * 1991-06-20 1997-03-25 Immuno Ag Arzneimittel enthaltend aktiviertes protein c
IT1262899B (it) * 1992-03-27 1996-07-22 Sclavo Spa Processo per l'isolamento di fattore ix, fattore x e fattore ii altamente purificati dal complesso protrombinico o dal plasma umano
DE4430204A1 (de) * 1994-08-26 1996-02-29 Behringwerke Ag Arzneimittel, welches als Gegenmittel für Blut-Antikoagulanzien geeignet ist und seine Verwendung
US5589571A (en) * 1994-10-28 1996-12-31 Cor Therapeutics, Inc. Process for production of inhibited forms of activated blood factors
US5714583A (en) 1995-06-07 1998-02-03 Genetics Institute, Inc. Factor IX purification methods
AT409334B (de) * 1997-09-19 2002-07-25 Immuno Ag Pharmazeutisches präparat enthaltend vitamin k-abhängige einzelfaktoren
SE0203551D0 (sv) * 2002-12-02 2002-12-02 Biovitrum Ab Prothrombin purification
US20060068454A1 (en) * 2004-09-27 2006-03-30 Sysmex Corporation Method of inactivating blood coagulation factor and blood coagulation factor-inactivated sample
GB0710321D0 (en) * 2007-05-30 2007-07-11 Nhs Blood & Transplant Method
US9956272B2 (en) 2007-05-30 2018-05-01 Bio Products Laboratory Limited Methods for preparing factor X, activated factor X, inactivated factor X and inactivated factor Xa, and pharmaceutical compositions comprising same
US20140206844A1 (en) 2013-01-18 2014-07-24 Prothera Biologics Methods for isolating blood products from an inter-alpha inhibitor protein-depleted blood product material
CN104328036B (zh) * 2014-10-28 2016-08-24 成都英德生物医药装备技术有限公司 一种人凝血酶原复合物吸附分离装置

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2303466C2 (de) * 1973-01-25 1975-03-20 Stanislaus Dipl.-Ing. 7340 Geislingen Malik Verfahren zur Herstellung eines Wabenträgers
JPS5263835A (en) * 1975-11-21 1977-05-26 Hokusan Kk Method of fabricating light shaped steel material
US4473553A (en) * 1983-12-02 1984-09-25 Miles Laboratories, Inc. Process for producing a lipoprotein-poor concentrate of coagulation factors VII and VIIa
FR2632309B1 (fr) * 1988-06-07 1990-08-24 Lille Transfusion Sanguine Procede de purification par voie chromatographique de proteines, notamment de facteur viii, et les produits obtenus
US4981952A (en) * 1988-10-04 1991-01-01 Eli Lilly And Company Method for the purification of vitamin K-dependent proteins

Also Published As

Publication number Publication date
AU627446B2 (en) 1992-08-27
NO178882B (no) 1996-03-18
NO902757L (no) 1990-06-21
NO178882C (no) 1996-06-26
EP0391974A1 (en) 1990-10-17
WO1989005650A2 (en) 1989-06-29
GB8729822D0 (en) 1988-02-03
DK153490D0 (da) 1990-06-22
ATE90567T1 (de) 1993-07-15
EP0391974B1 (en) 1993-06-16
AU3032989A (en) 1989-07-19
DE3881895D1 (de) 1993-07-22
JPH03501085A (ja) 1991-03-14
JPH0664B2 (ja) 1994-01-05
DE3881895T2 (de) 1993-12-02
WO1989005650A3 (en) 1989-07-27
DK175514B1 (da) 2004-11-15
NO902757D0 (no) 1990-06-21

Similar Documents

Publication Publication Date Title
DK153490A (da) Fremgangsmaade til oprensning af k-vitaminafhaengige blodkoagulationsfaktorer
ES2168387T3 (es) Procedimiento de fraccionamiento de soluciones que contienen sacarosa.
ATE200293T1 (de) Verfahren zur chromatographischen reinigung und trennung von nucleinsäuregemischen
DK0491757T3 (da) Fremgangsmåde til inaktivering af vira i blod og blodprodukter
DK84288D0 (da) Fusionsproteiner og oprensning deraf
DK0425066T3 (da) Krystallinsk 2-O-alpha-D-glucopyranosyl-L-ascorbinsyre og fremstilling heraf og anvendelser herfor
ATE216625T1 (de) Methode zur chromatographischen trennung von kationen aus wässrigen proben
DK124590A (da) Fremgangsmaade til ekstrahering af rene fraktioner af laktoperoxidase og laktoferrin af maelkeserum
MX168497B (es) Ultrafiltracion de flujo tangencial por afinidad
AU7264287A (en) A process for the preparation of a factor V concentrate
DK105988D0 (da) Apparat til adskillelse af blodkomponenter
EP0265809A3 (en) Cd-changer
ATE184018T1 (de) Verfahren zur isolation von hoch angereicherten faktoren ix, x und ii vom prothrombin komplex oder menschlichem plasma
ATE88718T1 (de) Verfahren zur reinigung des hepatitis-oberflaechen-antigens und das so erhaltene produkt.
HU9200225D0 (en) Complex process containing anti-coagulant ix-factor
DK0646594T3 (da) Fremgangsmåde til rensning af proteiner
DK514988D0 (da) Fremgangsmaade til industriel syntese af (2s,3as,7as)-2-carboxyperhydroindol
DE69434001D1 (de) Reinigung von vitamin-k abhaengigen proteinen durch membrane chromatographie
DK0383645T3 (da) Fremgangsmåde til fremstilling af antihæmofilifaktor (FVIIIc) med meget høj renhed
EP0112299A3 (en) Method for superoxidic-dismutasis purification via chromatography by affinity
DE3577809D1 (de) Verfahren zur trennung von wasserstoffisotopen.
DK59785D0 (da) Fremgangsmaade til fremstilling af i det vaesentlige fibrinogenfrit ahf
GR3015397T3 (en) Separation of anti-metal chelate antibodies.
DK0813597T3 (da) Fremgangsmåde til oprensning af vitamin K afhængige koaguleringsfaktorer ved kromatografi
DK0846166T3 (da) Fremgangsmåde til thrombinfremstilling

Legal Events

Date Code Title Description
PUP Patent expired
PBP Patent lapsed

Country of ref document: DK