DK1525198T3 - Acyloxypyrrolidinderivater og anvendelse af disse i egenskab af ligander for AVP's V1b-eller V1a-receptorer - Google Patents

Acyloxypyrrolidinderivater og anvendelse af disse i egenskab af ligander for AVP's V1b-eller V1a-receptorer

Info

Publication number
DK1525198T3
DK1525198T3 DK03753652T DK03753652T DK1525198T3 DK 1525198 T3 DK1525198 T3 DK 1525198T3 DK 03753652 T DK03753652 T DK 03753652T DK 03753652 T DK03753652 T DK 03753652T DK 1525198 T3 DK1525198 T3 DK 1525198T3
Authority
DK
Denmark
Prior art keywords
avp
ligands
receptors
acyloxypyrrolidine
derivatives
Prior art date
Application number
DK03753652T
Other languages
Danish (da)
English (en)
Inventor
Alain Aulombard
Georges Garcia
Antoine Pradines
Gal Claudine Serradeil-Le
Jean Wagnon
Original Assignee
Sanofi Aventis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis filed Critical Sanofi Aventis
Application granted granted Critical
Publication of DK1525198T3 publication Critical patent/DK1525198T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/06—Antiabortive agents; Labour repressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Diabetes (AREA)
  • Neurosurgery (AREA)
  • Endocrinology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Emergency Medicine (AREA)
  • Pregnancy & Childbirth (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Child & Adolescent Psychology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Vascular Medicine (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK03753652T 2002-07-19 2003-07-17 Acyloxypyrrolidinderivater og anvendelse af disse i egenskab af ligander for AVP's V1b-eller V1a-receptorer DK1525198T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0209242A FR2842527B1 (fr) 2002-07-19 2002-07-19 Derives d'acyloxypyrolidine, leur preparation et leur application en therapeutique

Publications (1)

Publication Number Publication Date
DK1525198T3 true DK1525198T3 (da) 2006-04-18

Family

ID=29797610

Family Applications (1)

Application Number Title Priority Date Filing Date
DK03753652T DK1525198T3 (da) 2002-07-19 2003-07-17 Acyloxypyrrolidinderivater og anvendelse af disse i egenskab af ligander for AVP's V1b-eller V1a-receptorer

Country Status (28)

Country Link
US (1) US7202267B2 (xx)
EP (1) EP1525198B1 (xx)
JP (1) JP4264414B2 (xx)
CN (1) CN100425608C (xx)
AR (1) AR040571A1 (xx)
AT (1) ATE312092T1 (xx)
AU (1) AU2003271815B8 (xx)
BR (1) BR0312800A (xx)
CA (1) CA2492224A1 (xx)
DE (1) DE60302670T2 (xx)
DK (1) DK1525198T3 (xx)
EA (1) EA008444B1 (xx)
ES (1) ES2254962T3 (xx)
FR (1) FR2842527B1 (xx)
HK (1) HK1074444A1 (xx)
HR (1) HRP20041231A2 (xx)
IL (1) IL165942A (xx)
IS (1) IS2487B (xx)
ME (1) MEP12408A (xx)
MX (1) MXPA05000822A (xx)
NO (1) NO20050292L (xx)
NZ (1) NZ537615A (xx)
PL (1) PL375309A1 (xx)
RS (1) RS20050018A (xx)
TW (1) TWI274751B (xx)
UA (1) UA78805C2 (xx)
WO (1) WO2004009585A2 (xx)
ZA (1) ZA200500478B (xx)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1659121A4 (en) 2003-08-28 2008-11-26 Taisho Pharmaceutical Co Ltd D RIV OF 1,3-DIHYDRO-2H-INDOL-2-ONE
TW200643015A (en) 2005-03-11 2006-12-16 Akzo Nobel Nv 2-(4-oxo-4H-quinazolin-3-yl)acetamide derivatives
DE102005015957A1 (de) * 2005-03-31 2006-10-05 Abbott Gmbh & Co. Kg Substituierte Oxindol-Derivate, diese enthaltende Arzneimittel und deren Verwendung
US8350043B2 (en) 2005-06-07 2013-01-08 Pharmacopeia, Inc. Azinone and diazinone V3 inhibitors for depression and stress disorders
NZ575426A (en) 2006-09-11 2010-09-30 Organon Nv Quinazolinone and isoquinolinone acetamide derivatives useful for the treatment of disorders which are influenced by modulation of the activity of the hpa axis
CN103864658B (zh) * 2014-03-06 2016-06-15 南京工业大学 氮杂环丁酮衍生物及其制备方法与应用
CN104447489B (zh) * 2014-12-29 2017-01-11 南京工业大学 3,4-二芳基马来酰亚胺衍生物及其制备方法与应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2804114B1 (fr) * 2000-01-25 2002-03-08 Sanofi Synthelabo Nouveaux derives de 1,3-dihydro-2h-indol-2-one, un procede pour leur preparation et les compositions pharmaceutiques en contenant

Also Published As

Publication number Publication date
ES2254962T3 (es) 2006-06-16
EA200500032A1 (ru) 2005-08-25
MEP12408A (en) 2010-06-10
AU2003271815A1 (en) 2004-02-09
NZ537615A (en) 2006-11-30
CN1681806A (zh) 2005-10-12
PL375309A1 (en) 2005-11-28
BR0312800A (pt) 2005-04-19
US7202267B2 (en) 2007-04-10
FR2842527A1 (fr) 2004-01-23
US20050192335A1 (en) 2005-09-01
UA78805C2 (en) 2007-04-25
CA2492224A1 (en) 2004-01-29
HRP20041231A2 (en) 2005-02-28
EP1525198B1 (fr) 2005-12-07
JP4264414B2 (ja) 2009-05-20
IS7641A (is) 2005-01-12
HK1074444A1 (en) 2005-11-11
FR2842527B1 (fr) 2005-01-28
IL165942A0 (en) 2006-01-15
NO20050292L (no) 2005-04-19
WO2004009585A2 (fr) 2004-01-29
AU2003271815B8 (en) 2009-04-30
JP2005537271A (ja) 2005-12-08
TWI274751B (en) 2007-03-01
IS2487B (is) 2008-12-15
MXPA05000822A (es) 2005-08-29
AR040571A1 (es) 2005-04-13
EP1525198A2 (fr) 2005-04-27
AU2003271815B2 (en) 2009-03-12
CN100425608C (zh) 2008-10-15
IL165942A (en) 2010-04-15
RS20050018A (xx) 2007-06-04
ZA200500478B (en) 2006-07-26
EA008444B1 (ru) 2007-06-29
ATE312092T1 (de) 2005-12-15
DE60302670T2 (de) 2006-09-07
DE60302670D1 (de) 2006-01-12
TW200410957A (en) 2004-07-01
WO2004009585A3 (fr) 2004-05-06

Similar Documents

Publication Publication Date Title
DK1255751T3 (da) Derivater af 1,3-dihydro-2H-indol-2-on og anvendelse heraf som ligander for V1B- eller V1B- og V1A-arginin-vasopressinreceptorer
ATE279396T1 (de) Imidazolderivate und ihre verwendung als somatostatin rezeptorliganden
ATE375987T1 (de) Arylmethyl-carbonylamino-thiazolderivate und ihre verwendung als antitumormittel
ATE360632T1 (de) Substituierte 8'-pyri(mi)dinyl-dihydrospiro- (cycloalkylamin)-pyrimido(1,2a)pyrimidin-6- onderivate
MA26390A1 (fr) Derives d'acyl-4-carboxyphenyluree, procedes pour les preparer et leur utilisation
DE60331444D1 (de) 1h-1,2,4- triazol-3- carboxamid derivate als cannabinoid-cb1 receptor liganden
MA28461B1 (fr) Derives d'heteroaryl- et phenylsulfamoyle substitues
ATE304008T1 (de) Benzimidiazole und pyridylimidazole derivate als liganden für gaba rezeptoren
DE60316012D1 (de) Purinderivate und ihre verwendung als liganden des cannabinoid rezeptors
ID22913A (id) Film dapat ditembus oleh gas
DE60103375D1 (de) 1,3-dihydro-2h-indol-2-on derivate und deren verwendung als liganden der arginin-vasopressin rezeptoren v1b oder v1b und v1a
DK1463759T3 (da) Ligand for den G-proteinkoblede receptor GPR43 og anvendelser deraf
EP1542721A4 (en) MODIFIED "S" ANTIBODIES
ATE287881T1 (de) 1,3-dihydro-2h-indol-2-on derivate und deren verwendung als liganden der arginin-vasopressin v1b und v1a rezeptoren
ITTO20030128A1 (it) Gruppo giunto resistente all'usura
ZA200500478B (en) Acyloxypyrrolidine derivatives and use thereof as ligands of V1B or both V1B and V1A receptors
DE602004010284D1 (de) Aminochinolinderivate und deren verwendung als adenosin-a3-liganden
ATE248838T1 (de) Azabzyclische 5ht1 rezeptor liganden
DE60009911D1 (de) Aminothiazolderivate und ihre verwendung als crf-rezeptor-liganden
DE50004104D1 (de) Indolderivate und deren verwendung als 5ht2a liganden
DE50313185D1 (de) 2-pyrrolidin-2-yl-ä1,3,4ü -oxadiazol-derivate und ihre verwendung als antidepressiva
FR2863143B3 (fr) Releveur d'epis
FR2845877B1 (fr) Support d'assise pliable
FR2852042B1 (fr) Piece d'aretier
DE29807030U1 (de) Umhängetasche