DK1516881T3 - Sammensætning og fremgangsmåde til modulering af dendritcelle-T-celle-interaktioner - Google Patents

Sammensætning og fremgangsmåde til modulering af dendritcelle-T-celle-interaktioner

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Publication number
DK1516881T3
DK1516881T3 DK04078220.3T DK04078220T DK1516881T3 DK 1516881 T3 DK1516881 T3 DK 1516881T3 DK 04078220 T DK04078220 T DK 04078220T DK 1516881 T3 DK1516881 T3 DK 1516881T3
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Prior art keywords
cells
cell
antibody
sign
clumping
Prior art date
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DK04078220.3T
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Danish (da)
English (en)
Inventor
Carl Gustav Figdor
Teunis Bernard Herman Geijtenbeek
Kooyk Yvette Van
Ruurd Torensma
Original Assignee
Univ Nijmegen
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Publication of DK1516881T3 publication Critical patent/DK1516881T3/da

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2851—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the lectin superfamily, e.g. CD23, CD72
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/515—Animal cells
    • A61K2039/5154—Antigen presenting cells [APCs], e.g. dendritic cells or macrophages
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Diabetes (AREA)
  • Rheumatology (AREA)
  • Hematology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Mycology (AREA)
  • Obesity (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • AIDS & HIV (AREA)
  • Pain & Pain Management (AREA)
  • Transplantation (AREA)
  • Pulmonology (AREA)
DK04078220.3T 1999-04-19 2000-04-19 Sammensætning og fremgangsmåde til modulering af dendritcelle-T-celle-interaktioner DK1516881T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP19990201204 EP1046651A1 (en) 1999-04-19 1999-04-19 Composition and method for modulating dendritic cell-T interaction
US17692400P 2000-01-20 2000-01-20
EP00921181A EP1086137B1 (en) 1999-04-19 2000-04-19 Composition and method for modulating dendritic cell-t cell interaction

Publications (1)

Publication Number Publication Date
DK1516881T3 true DK1516881T3 (da) 2010-09-27

Family

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Family Applications (2)

Application Number Title Priority Date Filing Date
DK04078220.3T DK1516881T3 (da) 1999-04-19 2000-04-19 Sammensætning og fremgangsmåde til modulering af dendritcelle-T-celle-interaktioner
DK00921181T DK1086137T3 (da) 1999-04-19 2000-04-19 Sammensætning og fremgangsmåde til at modulere dendritisk T-celle cellevekselvirkning

Family Applications After (1)

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DK00921181T DK1086137T3 (da) 1999-04-19 2000-04-19 Sammensætning og fremgangsmåde til at modulere dendritisk T-celle cellevekselvirkning

Country Status (13)

Country Link
US (4) US7148329B1 (https=)
EP (3) EP1046651A1 (https=)
JP (2) JP4989820B2 (https=)
KR (3) KR100923340B1 (https=)
AT (2) ATE472558T1 (https=)
AU (1) AU776317B2 (https=)
CA (1) CA2330231C (https=)
DE (2) DE60044621D1 (https=)
DK (2) DK1516881T3 (https=)
ES (2) ES2346877T3 (https=)
NZ (1) NZ508723A (https=)
PT (2) PT1086137E (https=)
WO (1) WO2000063251A1 (https=)

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Also Published As

Publication number Publication date
EP1516881B1 (en) 2010-06-30
KR20080098678A (ko) 2008-11-11
DK1086137T3 (da) 2008-10-27
KR20070094990A (ko) 2007-09-27
JP4989820B2 (ja) 2012-08-01
ES2307502T3 (es) 2008-12-01
EP1086137A1 (en) 2001-03-28
NZ508723A (en) 2003-12-19
HK1036285A1 (en) 2001-12-28
US20050220804A1 (en) 2005-10-06
DE60044621D1 (de) 2010-08-12
PT1086137E (pt) 2008-09-09
US20080160041A1 (en) 2008-07-03
KR100952883B1 (ko) 2010-04-16
ATE398140T1 (de) 2008-07-15
DE60039151D1 (de) 2008-07-24
AU4152600A (en) 2000-11-02
US7285642B2 (en) 2007-10-23
JP2010285450A (ja) 2010-12-24
KR100923340B1 (ko) 2009-10-22
CA2330231A1 (en) 2000-10-26
ES2346877T3 (es) 2010-10-21
EP1046651A1 (en) 2000-10-25
PT1516881E (pt) 2010-08-25
EP1516881A2 (en) 2005-03-23
JP2003502283A (ja) 2003-01-21
US8105599B2 (en) 2012-01-31
JP5363432B2 (ja) 2013-12-11
AU776317B2 (en) 2004-09-02
EP1516881A3 (en) 2005-08-31
EP1086137B1 (en) 2008-06-11
US20050118168A1 (en) 2005-06-02
US7148329B1 (en) 2006-12-12
WO2000063251A1 (en) 2000-10-26
KR20010071530A (ko) 2001-07-28
ATE472558T1 (de) 2010-07-15
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