DK1497292T3 - Azaindolylpiperidinderivater som antihistamin- og antiallergimidler - Google Patents
Azaindolylpiperidinderivater som antihistamin- og antiallergimidlerInfo
- Publication number
- DK1497292T3 DK1497292T3 DK03745302T DK03745302T DK1497292T3 DK 1497292 T3 DK1497292 T3 DK 1497292T3 DK 03745302 T DK03745302 T DK 03745302T DK 03745302 T DK03745302 T DK 03745302T DK 1497292 T3 DK1497292 T3 DK 1497292T3
- Authority
- DK
- Denmark
- Prior art keywords
- azaindolylpiperidine
- antihistamine
- derivatives
- allergy agents
- allergy
- Prior art date
Links
- GUGOEEXESWIERI-UHFFFAOYSA-N Terfenadine Chemical compound C1=CC(C(C)(C)C)=CC=C1C(O)CCCN1CCC(C(O)(C=2C=CC=CC=2)C=2C=CC=CC=2)CC1 GUGOEEXESWIERI-UHFFFAOYSA-N 0.000 title 1
- 230000001387 anti-histamine Effects 0.000 title 1
- 239000000043 antiallergic agent Substances 0.000 title 1
- 239000000739 antihistaminic agent Substances 0.000 title 1
- 102000000543 Histamine Receptors Human genes 0.000 abstract 1
- 108010002059 Histamine Receptors Proteins 0.000 abstract 1
- 239000005557 antagonist Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Health & Medical Sciences (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Ophthalmology & Optometry (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES200200753A ES2201899B1 (es) | 2002-04-01 | 2002-04-01 | Derivados de la azaindolilpiperidina como agentes antihistaminicos y antialergicos. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1497292T3 true DK1497292T3 (da) | 2006-10-16 |
Family
ID=28459671
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK03745302T DK1497292T3 (da) | 2002-04-01 | 2003-04-01 | Azaindolylpiperidinderivater som antihistamin- og antiallergimidler |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US7622480B2 (https=) |
| EP (1) | EP1497292B1 (https=) |
| JP (1) | JP2005526816A (https=) |
| AT (1) | ATE329916T1 (https=) |
| AU (1) | AU2003226765A1 (https=) |
| DE (1) | DE60306138T2 (https=) |
| DK (1) | DK1497292T3 (https=) |
| ES (2) | ES2201899B1 (https=) |
| PT (1) | PT1497292E (https=) |
| WO (1) | WO2003082867A1 (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2382037C2 (ru) * | 2003-11-17 | 2010-02-20 | Бёрингер Ингельхайм Интернациональ Гмбх | Новые пиперидинзамещенные индолы или их гетеропроизводные |
| AU2006239302B2 (en) * | 2005-04-26 | 2011-07-07 | Hypnion, Inc. | Benzisoxazole piperazine compounds and methods of use thereof |
| ATE531706T1 (de) | 2005-04-30 | 2011-11-15 | Boehringer Ingelheim Int | Neue piperidin-substituierte indole und ihre verwendung als ccr-3-modulatoren |
| US20080015214A1 (en) * | 2005-10-24 | 2008-01-17 | Bignan Gilles C | 3-piperidin-4-yl-indole orl-1 receptor modulators |
| ATE524461T1 (de) * | 2006-10-27 | 2011-09-15 | Boehringer Ingelheim Int | Neue substituierte piperidylpropanthiole |
| EP2079725B1 (en) * | 2006-10-27 | 2011-12-14 | Boehringer Ingelheim International GmbH | Piperidyl-propane-thiol ccr3 modulators |
| JP2014515368A (ja) | 2011-05-26 | 2014-06-30 | 第一三共株式会社 | プロテインキナーゼ阻害剤としての複素環化合物 |
| MA40759A (fr) | 2014-09-26 | 2017-08-01 | Pfizer | Modulateurs de rorc2 de type pyrrolopyridine substitué par un méthyle et trifluorométhyle et leurs procédés d'utilisation |
| NZ732511A (en) | 2014-12-15 | 2018-11-30 | Univ Michigan Regents | Small molecule inhibitors of egfr and pi3k |
| KR101660863B1 (ko) * | 2015-04-03 | 2016-09-28 | 주식회사 녹십자 | IKKε 및 TBK1 억제제로서의 7-아자인돌 또는 4,7-다이아자인돌 유도체 및 이를 포함하는 약학적 조성물 |
| US20240239764A1 (en) | 2020-12-22 | 2024-07-18 | Mekanistic Therapeutics | Substituted aminobenzyl heteroaryl compounds as egfr and/or pi3k inhibitors |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2139595T3 (es) * | 1991-04-23 | 2000-02-16 | Toray Industries | Derivados triazolicos triciclicos, fabricacion de los mismos y su utilizacion. |
| AU3176297A (en) * | 1996-06-25 | 1998-01-14 | Novartis Ag | Substituted 7-amino-pyrrolo{3,2-d}pyrimidines and the use thereof |
| ZA979961B (en) * | 1996-11-15 | 1999-05-05 | Lilly Co Eli | 5-HT1F agonists |
| ES2165274B1 (es) * | 1999-06-04 | 2003-04-01 | Almirall Prodesfarma Sa | Nuevos derivados de indolilpiperidina como agentes antihistaminicos y antialergicos. |
| HK1052705B (en) | 2000-08-14 | 2006-09-29 | Ortho-Mcneil Pharmaceutical, Inc. | Substituted pyrazole |
| PT1315492E (pt) * | 2000-09-06 | 2008-10-01 | Ortho Mcneil Pharm Inc | Utilização de pirazoles substituídos para o tratamento de alergias |
| ES2172436B1 (es) * | 2000-10-31 | 2004-01-16 | Almirall Prodesfarma Sa | Derivados de indolilpiperidina como agentes antihistaminicos y antialergicos. |
| WO2002051837A2 (en) | 2000-12-22 | 2002-07-04 | Wyeth | Heterocyclindazole and azaindazole compounds as 5-hydroxytryptamine-6 ligands |
| WO2002079151A1 (en) | 2001-03-29 | 2002-10-10 | Smithkline Beecham P.L.C. | 3-substituted indoels or fused pyrroles as antagonists of the chemokine mcp-1 (ccr2b) receptor |
-
2002
- 2002-04-01 ES ES200200753A patent/ES2201899B1/es not_active Expired - Fee Related
-
2003
- 2003-04-01 ES ES03745302T patent/ES2265577T3/es not_active Expired - Lifetime
- 2003-04-01 WO PCT/EP2003/003377 patent/WO2003082867A1/en not_active Ceased
- 2003-04-01 DK DK03745302T patent/DK1497292T3/da active
- 2003-04-01 JP JP2003580332A patent/JP2005526816A/ja not_active Ceased
- 2003-04-01 EP EP03745302A patent/EP1497292B1/en not_active Expired - Lifetime
- 2003-04-01 DE DE60306138T patent/DE60306138T2/de not_active Expired - Lifetime
- 2003-04-01 AT AT03745302T patent/ATE329916T1/de not_active IP Right Cessation
- 2003-04-01 US US10/509,279 patent/US7622480B2/en not_active Expired - Fee Related
- 2003-04-01 AU AU2003226765A patent/AU2003226765A1/en not_active Abandoned
- 2003-04-01 PT PT03745302T patent/PT1497292E/pt unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU2003226765A8 (en) | 2003-10-13 |
| ES2201899A1 (es) | 2004-03-16 |
| WO2003082867A1 (en) | 2003-10-09 |
| ES2201899B1 (es) | 2005-06-01 |
| DE60306138T2 (de) | 2007-05-03 |
| EP1497292B1 (en) | 2006-06-14 |
| ES2265577T3 (es) | 2007-02-16 |
| AU2003226765A1 (en) | 2003-10-13 |
| EP1497292A1 (en) | 2005-01-19 |
| WO2003082867A8 (en) | 2004-11-04 |
| PT1497292E (pt) | 2006-10-31 |
| ATE329916T1 (de) | 2006-07-15 |
| US20050176751A1 (en) | 2005-08-11 |
| DE60306138D1 (de) | 2006-07-27 |
| JP2005526816A (ja) | 2005-09-08 |
| US7622480B2 (en) | 2009-11-24 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK1513826T3 (da) | Hidtil ukendte indolylpiperidinderivater som kraftige antihistamin- og antiallergimidler | |
| ATE371656T1 (de) | Heteroaryl-pyrimidinderivate als jak-inhibitoren | |
| WO2003087094A3 (en) | Pyrrolidinium derivatives as antagonists of m3 muscarinic receptors | |
| ES2195785B1 (es) | Nuevos derivados de piridazin-3(2h)-ona. | |
| NO20034122L (no) | Sammensmeltede pyridinderivater for anvendelse som vanilloidreseptorantagonister for behandling av smerte | |
| AU2002331391A1 (en) | N-monoacylated derivatives of o-phenylenediamines, their six membered heterocyclic analogues and their use as pharmaceutical agents | |
| NO20071074L (no) | Substituerte cykliske ureaderivater, fremstilling derav og farmasoytisk anvendelse derav som kinaseinhibitorer | |
| JO2355B1 (en) | Hereditary calcitonin polypeptide receptor antagonists | |
| BRPI0415709A (pt) | esquemas terapêuticos para antagonistas de baff | |
| ATE532781T1 (de) | 5-(acylamino)indazol-derivate als kinase- inhibitoren | |
| NO20042844L (no) | 4-(piperidyl- og pyrrolidyl-alkyl-ureido)-kinoliner som uprotensin II reseptor-antagonister | |
| WO2003091259A8 (en) | Triaryl-oxy-aryl-spiro-pyrimidine-2, 4, 6-trione metalloproteinase inhibitors | |
| UY28529A1 (es) | Nuevos derivados de pirimidin-2-amina | |
| CY1106927T1 (el) | Φαρμακευτικη συνθεση ενος pde4 ή pde3/4 αναστολεα και ανταγωνιστη υποδοχεα ισταμινης | |
| WO2005060959A8 (en) | Pyrazole derivatives and use thereof as orexin receptor antagonists | |
| DK1497292T3 (da) | Azaindolylpiperidinderivater som antihistamin- og antiallergimidler | |
| DK1448562T3 (da) | Substituerede tetracycliske pyrroloquinolonderivater egnede som phosphodiesteraseinhibitorer | |
| DE60318694D1 (de) | 4-(pyrrolopyrimidin-6-yl)benzolsulfonamidderivate | |
| MEP19108A (en) | Aminoquinoline derivatives and their use as adenosine a3 ligands | |
| NO20072078L (no) | Indolderivater som inhibitorer av loselig adenylsyklase | |
| SE0303480D0 (sv) | Benzofuranes | |
| NO20061981L (no) | Arylindenopyridiner og arylindenopyridiner og deres anvendelse som adenosin A2A reseptoragonist | |
| DE602005027870D1 (de) | Cgrp-rezeptorantagonisten | |
| ATE325115T1 (de) | Pyrimidinderivate als selektive cox-2-inhibitoren | |
| ATE274515T1 (de) | Pyrazolopyridinderivate |