AU2003226765A1 - Azaindolylpiperidine derivatives as antihistaminic and antiallergic agents - Google Patents

Azaindolylpiperidine derivatives as antihistaminic and antiallergic agents

Info

Publication number
AU2003226765A1
AU2003226765A1 AU2003226765A AU2003226765A AU2003226765A1 AU 2003226765 A1 AU2003226765 A1 AU 2003226765A1 AU 2003226765 A AU2003226765 A AU 2003226765A AU 2003226765 A AU2003226765 A AU 2003226765A AU 2003226765 A1 AU2003226765 A1 AU 2003226765A1
Authority
AU
Australia
Prior art keywords
azaindolylpiperidine
antihistaminic
derivatives
antiallergic agents
antiallergic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2003226765A
Other languages
English (en)
Other versions
AU2003226765A8 (en
Inventor
Aranzazu Cardus Figueras
Silvia Fonquerna Pou
Luis Miguel Pages Santacana
Carlos Puig Duran
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Almirall SA
Original Assignee
Almirall Prodesfarma SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Almirall Prodesfarma SA filed Critical Almirall Prodesfarma SA
Publication of AU2003226765A8 publication Critical patent/AU2003226765A8/xx
Publication of AU2003226765A1 publication Critical patent/AU2003226765A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU2003226765A 2002-04-01 2003-04-01 Azaindolylpiperidine derivatives as antihistaminic and antiallergic agents Abandoned AU2003226765A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ESP200200753 2002-04-01
ES200200753A ES2201899B1 (es) 2002-04-01 2002-04-01 Derivados de la azaindolilpiperidina como agentes antihistaminicos y antialergicos.
PCT/EP2003/003377 WO2003082867A1 (en) 2002-04-01 2003-04-01 Azaindolylpiperidine derivatives as antihistaminic and antiallergic agents

Publications (2)

Publication Number Publication Date
AU2003226765A8 AU2003226765A8 (en) 2003-10-13
AU2003226765A1 true AU2003226765A1 (en) 2003-10-13

Family

ID=28459671

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003226765A Abandoned AU2003226765A1 (en) 2002-04-01 2003-04-01 Azaindolylpiperidine derivatives as antihistaminic and antiallergic agents

Country Status (10)

Country Link
US (1) US7622480B2 (https=)
EP (1) EP1497292B1 (https=)
JP (1) JP2005526816A (https=)
AT (1) ATE329916T1 (https=)
AU (1) AU2003226765A1 (https=)
DE (1) DE60306138T2 (https=)
DK (1) DK1497292T3 (https=)
ES (2) ES2201899B1 (https=)
PT (1) PT1497292E (https=)
WO (1) WO2003082867A1 (https=)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2382037C2 (ru) * 2003-11-17 2010-02-20 Бёрингер Ингельхайм Интернациональ Гмбх Новые пиперидинзамещенные индолы или их гетеропроизводные
AU2006239302B2 (en) * 2005-04-26 2011-07-07 Hypnion, Inc. Benzisoxazole piperazine compounds and methods of use thereof
ATE531706T1 (de) 2005-04-30 2011-11-15 Boehringer Ingelheim Int Neue piperidin-substituierte indole und ihre verwendung als ccr-3-modulatoren
US20080015214A1 (en) * 2005-10-24 2008-01-17 Bignan Gilles C 3-piperidin-4-yl-indole orl-1 receptor modulators
ATE524461T1 (de) * 2006-10-27 2011-09-15 Boehringer Ingelheim Int Neue substituierte piperidylpropanthiole
EP2079725B1 (en) * 2006-10-27 2011-12-14 Boehringer Ingelheim International GmbH Piperidyl-propane-thiol ccr3 modulators
JP2014515368A (ja) 2011-05-26 2014-06-30 第一三共株式会社 プロテインキナーゼ阻害剤としての複素環化合物
MA40759A (fr) 2014-09-26 2017-08-01 Pfizer Modulateurs de rorc2 de type pyrrolopyridine substitué par un méthyle et trifluorométhyle et leurs procédés d'utilisation
NZ732511A (en) 2014-12-15 2018-11-30 Univ Michigan Regents Small molecule inhibitors of egfr and pi3k
KR101660863B1 (ko) * 2015-04-03 2016-09-28 주식회사 녹십자 IKKε 및 TBK1 억제제로서의 7-아자인돌 또는 4,7-다이아자인돌 유도체 및 이를 포함하는 약학적 조성물
US20240239764A1 (en) 2020-12-22 2024-07-18 Mekanistic Therapeutics Substituted aminobenzyl heteroaryl compounds as egfr and/or pi3k inhibitors

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2139595T3 (es) * 1991-04-23 2000-02-16 Toray Industries Derivados triazolicos triciclicos, fabricacion de los mismos y su utilizacion.
AU3176297A (en) * 1996-06-25 1998-01-14 Novartis Ag Substituted 7-amino-pyrrolo{3,2-d}pyrimidines and the use thereof
ZA979961B (en) * 1996-11-15 1999-05-05 Lilly Co Eli 5-HT1F agonists
ES2165274B1 (es) * 1999-06-04 2003-04-01 Almirall Prodesfarma Sa Nuevos derivados de indolilpiperidina como agentes antihistaminicos y antialergicos.
HK1052705B (en) 2000-08-14 2006-09-29 Ortho-Mcneil Pharmaceutical, Inc. Substituted pyrazole
PT1315492E (pt) * 2000-09-06 2008-10-01 Ortho Mcneil Pharm Inc Utilização de pirazoles substituídos para o tratamento de alergias
ES2172436B1 (es) * 2000-10-31 2004-01-16 Almirall Prodesfarma Sa Derivados de indolilpiperidina como agentes antihistaminicos y antialergicos.
WO2002051837A2 (en) 2000-12-22 2002-07-04 Wyeth Heterocyclindazole and azaindazole compounds as 5-hydroxytryptamine-6 ligands
WO2002079151A1 (en) 2001-03-29 2002-10-10 Smithkline Beecham P.L.C. 3-substituted indoels or fused pyrroles as antagonists of the chemokine mcp-1 (ccr2b) receptor

Also Published As

Publication number Publication date
AU2003226765A8 (en) 2003-10-13
ES2201899A1 (es) 2004-03-16
WO2003082867A1 (en) 2003-10-09
ES2201899B1 (es) 2005-06-01
DE60306138T2 (de) 2007-05-03
EP1497292B1 (en) 2006-06-14
ES2265577T3 (es) 2007-02-16
EP1497292A1 (en) 2005-01-19
WO2003082867A8 (en) 2004-11-04
PT1497292E (pt) 2006-10-31
DK1497292T3 (da) 2006-10-16
ATE329916T1 (de) 2006-07-15
US20050176751A1 (en) 2005-08-11
DE60306138D1 (de) 2006-07-27
JP2005526816A (ja) 2005-09-08
US7622480B2 (en) 2009-11-24

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase