DK148688C - Analogifremgangsmaade til fremstilling af basisk substituerede 7-alkylteofyllinderivater eller salte deraf med farmaceutisk acceptable syrer - Google Patents

Analogifremgangsmaade til fremstilling af basisk substituerede 7-alkylteofyllinderivater eller salte deraf med farmaceutisk acceptable syrer

Info

Publication number
DK148688C
DK148688C DK322882A DK322882A DK148688C DK 148688 C DK148688 C DK 148688C DK 322882 A DK322882 A DK 322882A DK 322882 A DK322882 A DK 322882A DK 148688 C DK148688 C DK 148688C
Authority
DK
Denmark
Prior art keywords
derivatives
alkylteophylline
analogue
salts
preparation
Prior art date
Application number
DK322882A
Other languages
English (en)
Other versions
DK322882A (da
DK148688B (da
Inventor
Kurt Thiele
Felix Geissmann
Ludwig Zirngibl
Ulrich Jahn
Original Assignee
Siegfried Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Siegfried Ag filed Critical Siegfried Ag
Publication of DK322882A publication Critical patent/DK322882A/da
Publication of DK148688B publication Critical patent/DK148688B/da
Application granted granted Critical
Publication of DK148688C publication Critical patent/DK148688C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
    • C07D473/08—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3 with methyl radicals in positions 1 and 3, e.g. theophylline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Financial Or Insurance-Related Operations Such As Payment And Settlement (AREA)
  • Lubricants (AREA)
  • Control Of Transmission Device (AREA)
  • Saccharide Compounds (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Catalysts (AREA)
DK322882A 1981-07-20 1982-07-19 Analogifremgangsmaade til fremstilling af basisk substituerede 7-alkylteofyllinderivater eller salte deraf med farmaceutisk acceptable syrer DK148688C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH473981 1981-07-20
CH4739/81A CH648559A5 (de) 1981-07-20 1981-07-20 Theophyllinderivate und verfahren zu deren herstellung.

Publications (3)

Publication Number Publication Date
DK322882A DK322882A (da) 1983-01-21
DK148688B DK148688B (da) 1985-09-02
DK148688C true DK148688C (da) 1986-02-24

Family

ID=4281658

Family Applications (1)

Application Number Title Priority Date Filing Date
DK322882A DK148688C (da) 1981-07-20 1982-07-19 Analogifremgangsmaade til fremstilling af basisk substituerede 7-alkylteofyllinderivater eller salte deraf med farmaceutisk acceptable syrer

Country Status (19)

Country Link
US (2) US4603204A (da)
EP (1) EP0071738B1 (da)
JP (1) JPS5824585A (da)
KR (1) KR880001283B1 (da)
AT (1) ATE18047T1 (da)
AU (1) AU562299B2 (da)
CA (1) CA1202971A (da)
CH (1) CH648559A5 (da)
DE (1) DE3269160D1 (da)
DK (1) DK148688C (da)
ES (1) ES8304981A1 (da)
FI (1) FI78297C (da)
GR (1) GR76221B (da)
HU (1) HU189160B (da)
IE (1) IE53583B1 (da)
PH (1) PH19076A (da)
SU (1) SU1114337A3 (da)
WO (1) WO1987000841A1 (da)
ZA (1) ZA825123B (da)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH648559A5 (de) * 1981-07-20 1985-03-29 Siegfried Ag Theophyllinderivate und verfahren zu deren herstellung.
EP0087810B1 (en) * 1982-03-02 1986-06-25 Eisai Co., Ltd. Antiphlogistic/antipyretic/analgesic pharmaceutical compositions containing theophylline derivatives as active ingredient
JPS6063658U (ja) * 1983-10-07 1985-05-04 日本フレツクス工業株式会社 フック装置の離隔解除機構
FR2558162B1 (fr) * 1984-01-17 1986-04-25 Adir Nouveaux derives de la xanthine, leurs procedes de preparation et les compositions pharmaceutiques les renfermant
US4548939A (en) * 1984-10-01 1985-10-22 Janssen Pharmaceutica N. V. 1H-Indol-3-yl containing 1,3-dimethyl-1H-purine-2,6-diones
JPH0615529B2 (ja) * 1985-04-01 1994-03-02 エーザイ株式会社 新規ピペリジン誘導体
US4810706A (en) * 1985-12-20 1989-03-07 Recherche Syntex Piperazine derivatives of theophylline and theobromine
EP0229897A1 (de) * 1985-12-26 1987-07-29 Siegfried Aktiengesellschaft Alpha1-adrenerg blockierende Theophyllinderivate
US4716165A (en) * 1986-09-24 1987-12-29 American Home Products Corporation Histamine H1 antagonists
AU593194B2 (en) * 1986-09-26 1990-02-01 Sumitomo Pharmaceuticals Company, Limited Imide derivatives ,and their production and use
US4716166A (en) * 1986-10-21 1987-12-29 American Home Products Corporation Histamine H1 antagonists
CA1283910C (en) * 1986-10-21 1991-05-07 Magid A. Abou-Gharbia Histamine h _antagonists
GB8716313D0 (en) * 1987-07-10 1987-08-19 Janssen Pharmaceutica Nv 2-(heterocyclylalkyl)imidazopyridines
IL109161A0 (en) * 1993-03-31 1994-06-24 Cell Therapeutics Inc Amino alcohol derivatives, methods for the preparation thereof, and pharmaceutical compositions containing the same
US5837703A (en) * 1993-03-31 1998-11-17 Cell Therapeutics, Inc. Amino-alcohol substituted cyclic compounds
US5641783A (en) * 1993-11-12 1997-06-24 Cell Therapeutics, Inc. Substituted amino alcohol compounds
JP3850480B2 (ja) * 1996-01-29 2006-11-29 中央発條株式会社 ケーブルを用いた遠隔操作装置
TWI268930B (en) * 2000-07-28 2006-12-21 Ing-Jun Chen Theophylline and 3-isobutyl-1-methylxanthine based N-7 substituted derivatives and pharmaceutical composition thereof
RU2333212C3 (ru) * 2007-03-29 2019-08-26 Общество С Ограниченной Ответственностью "Фармвинг" ПРОИЗВОДНЫЕ 1-И 7-[ω-(БЕНЗГИДРИЛ-4-ПИПЕРАЗИНИЛ-1)АЛКИЛ]-3-АЛКИЛКСАНТИНОВ, ОБЛАДАЮЩИЕ ПРОТИВОГИСТАМИННОЙ И АНТИАЛЛЕРГИЧЕСКОЙ АКТИВНОСТЬЮ
EA017351B1 (ru) * 2007-03-29 2012-11-30 Общество С Ограниченной Ответственностью "Фармвинг" Средство противогистаминного антиаллергического действия и способ его получения
US20230349922A1 (en) 2020-08-11 2023-11-02 Université De Strasbourg H2 Blockers Targeting Liver Macrophages for the Prevention and Treatment of Liver Disease and Cancer

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1133989A (en) * 1964-12-08 1968-11-20 Chugai Pharmaceutical Co Ltd Theophylline derivatives, their salts and process for preparing the same
DE1966620A1 (de) * 1969-03-20 1973-05-24 Walter Dr Bestian Verfahren zur herstellung von dialkylxanthin-derivaten
ES377662A1 (es) * 1969-03-28 1973-01-01 Walter Bestian Procedimiento para la preparacion de nuevos compuestos de derivados de dialcohil-xantina.
DE2550000A1 (de) * 1975-11-07 1977-05-12 Boehringer Mannheim Gmbh Neue purin-derivate und verfahren zu ihrer herstellung
DE2922159A1 (de) * 1979-05-31 1980-12-04 Boehringer Mannheim Gmbh Neue xanthin-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
JPS5618983A (en) * 1979-07-25 1981-02-23 Eisai Co Ltd Theophylline derivative and its preapration
CH648559A5 (de) * 1981-07-20 1985-03-29 Siegfried Ag Theophyllinderivate und verfahren zu deren herstellung.
US4400381A (en) * 1981-07-31 1983-08-23 Laroche-Navarron, S.A. Piperazine derivatives of theophylline
FR2531085A1 (fr) * 1982-07-28 1984-02-03 Adir Nouveaux derives de la xanthine, leur procede de preparation et les compositions pharmaceutiques les renfermant
US4548939A (en) * 1984-10-01 1985-10-22 Janssen Pharmaceutica N. V. 1H-Indol-3-yl containing 1,3-dimethyl-1H-purine-2,6-diones

Also Published As

Publication number Publication date
US4668786A (en) 1987-05-26
EP0071738B1 (de) 1986-02-19
FI78297B (fi) 1989-03-31
US4603204A (en) 1986-07-29
IE821728L (en) 1983-01-20
ES514169A0 (es) 1983-04-01
KR880001283B1 (ko) 1988-07-18
JPS5824585A (ja) 1983-02-14
GR76221B (da) 1984-08-04
SU1114337A3 (ru) 1984-09-15
EP0071738A1 (de) 1983-02-16
AU562299B2 (en) 1987-06-04
ZA825123B (en) 1983-05-25
PH19076A (en) 1985-12-19
CA1202971A (en) 1986-04-08
FI78297C (fi) 1989-07-10
DK322882A (da) 1983-01-21
FI822527L (fi) 1983-01-21
ES8304981A1 (es) 1983-04-01
KR840000548A (ko) 1984-02-25
IE53583B1 (en) 1988-12-21
ATE18047T1 (de) 1986-03-15
AU8604882A (en) 1983-01-27
HU189160B (en) 1986-06-30
DE3269160D1 (en) 1986-03-27
WO1987000841A1 (en) 1987-02-12
DK148688B (da) 1985-09-02
FI822527A0 (fi) 1982-07-16
CH648559A5 (de) 1985-03-29

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Legal Events

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AHS Application shelved for other reasons than non-payment