DK148688C - Analogifremgangsmaade til fremstilling af basisk substituerede 7-alkylteofyllinderivater eller salte deraf med farmaceutisk acceptable syrer - Google Patents
Analogifremgangsmaade til fremstilling af basisk substituerede 7-alkylteofyllinderivater eller salte deraf med farmaceutisk acceptable syrerInfo
- Publication number
- DK148688C DK148688C DK322882A DK322882A DK148688C DK 148688 C DK148688 C DK 148688C DK 322882 A DK322882 A DK 322882A DK 322882 A DK322882 A DK 322882A DK 148688 C DK148688 C DK 148688C
- Authority
- DK
- Denmark
- Prior art keywords
- derivatives
- alkylteophylline
- analogue
- salts
- preparation
- Prior art date
Links
- 239000002253 acid Substances 0.000 title 1
- 150000007513 acids Chemical class 0.000 title 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 230000003042 antagnostic effect Effects 0.000 abstract 1
- 230000001466 anti-adreneric effect Effects 0.000 abstract 1
- 230000002804 anti-anaphylactic effect Effects 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 125000001188 haloalkyl group Chemical group 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 125000001072 heteroaryl group Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 230000004936 stimulating effect Effects 0.000 abstract 1
- ZFXYFBGIUFBOJW-UHFFFAOYSA-N theophylline Chemical class O=C1N(C)C(=O)N(C)C2=C1NC=N2 ZFXYFBGIUFBOJW-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
- C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
- C07D473/08—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3 with methyl radicals in positions 1 and 3, e.g. theophylline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Control Of Transmission Device (AREA)
- Financial Or Insurance-Related Operations Such As Payment And Settlement (AREA)
- Lubricants (AREA)
- Saccharide Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Steroid Compounds (AREA)
- Catalysts (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH4739/81A CH648559A5 (de) | 1981-07-20 | 1981-07-20 | Theophyllinderivate und verfahren zu deren herstellung. |
| CH473981 | 1981-07-20 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| DK322882A DK322882A (da) | 1983-01-21 |
| DK148688B DK148688B (da) | 1985-09-02 |
| DK148688C true DK148688C (da) | 1986-02-24 |
Family
ID=4281658
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK322882A DK148688C (da) | 1981-07-20 | 1982-07-19 | Analogifremgangsmaade til fremstilling af basisk substituerede 7-alkylteofyllinderivater eller salte deraf med farmaceutisk acceptable syrer |
Country Status (19)
| Country | Link |
|---|---|
| US (2) | US4603204A (da) |
| EP (1) | EP0071738B1 (da) |
| JP (1) | JPS5824585A (da) |
| KR (1) | KR880001283B1 (da) |
| AT (1) | ATE18047T1 (da) |
| AU (1) | AU562299B2 (da) |
| CA (1) | CA1202971A (da) |
| CH (1) | CH648559A5 (da) |
| DE (1) | DE3269160D1 (da) |
| DK (1) | DK148688C (da) |
| ES (1) | ES8304981A1 (da) |
| FI (1) | FI78297C (da) |
| GR (1) | GR76221B (da) |
| HU (1) | HU189160B (da) |
| IE (1) | IE53583B1 (da) |
| PH (1) | PH19076A (da) |
| SU (1) | SU1114337A3 (da) |
| WO (1) | WO1987000841A1 (da) |
| ZA (1) | ZA825123B (da) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH648559A5 (de) * | 1981-07-20 | 1985-03-29 | Siegfried Ag | Theophyllinderivate und verfahren zu deren herstellung. |
| EP0087810B1 (en) * | 1982-03-02 | 1986-06-25 | Eisai Co., Ltd. | Antiphlogistic/antipyretic/analgesic pharmaceutical compositions containing theophylline derivatives as active ingredient |
| JPS6063658U (ja) * | 1983-10-07 | 1985-05-04 | 日本フレツクス工業株式会社 | フック装置の離隔解除機構 |
| FR2558162B1 (fr) * | 1984-01-17 | 1986-04-25 | Adir | Nouveaux derives de la xanthine, leurs procedes de preparation et les compositions pharmaceutiques les renfermant |
| US4548939A (en) * | 1984-10-01 | 1985-10-22 | Janssen Pharmaceutica N. V. | 1H-Indol-3-yl containing 1,3-dimethyl-1H-purine-2,6-diones |
| JPH0615529B2 (ja) * | 1985-04-01 | 1994-03-02 | エーザイ株式会社 | 新規ピペリジン誘導体 |
| US4810706A (en) * | 1985-12-20 | 1989-03-07 | Recherche Syntex | Piperazine derivatives of theophylline and theobromine |
| EP0229897A1 (de) * | 1985-12-26 | 1987-07-29 | Siegfried Aktiengesellschaft | Alpha1-adrenerg blockierende Theophyllinderivate |
| US4716165A (en) * | 1986-09-24 | 1987-12-29 | American Home Products Corporation | Histamine H1 antagonists |
| JP2660407B2 (ja) * | 1986-09-26 | 1997-10-08 | 住友製薬株式会社 | 新規なイミド誘導体 |
| CA1283910C (en) * | 1986-10-21 | 1991-05-07 | Magid A. Abou-Gharbia | Histamine h _antagonists |
| US4716166A (en) * | 1986-10-21 | 1987-12-29 | American Home Products Corporation | Histamine H1 antagonists |
| GB8716313D0 (en) * | 1987-07-10 | 1987-08-19 | Janssen Pharmaceutica Nv | 2-(heterocyclylalkyl)imidazopyridines |
| US5641783A (en) * | 1993-11-12 | 1997-06-24 | Cell Therapeutics, Inc. | Substituted amino alcohol compounds |
| US5837703A (en) * | 1993-03-31 | 1998-11-17 | Cell Therapeutics, Inc. | Amino-alcohol substituted cyclic compounds |
| IL109161A0 (en) * | 1993-03-31 | 1994-06-24 | Cell Therapeutics Inc | Amino alcohol derivatives, methods for the preparation thereof, and pharmaceutical compositions containing the same |
| JP3850480B2 (ja) * | 1996-01-29 | 2006-11-29 | 中央発條株式会社 | ケーブルを用いた遠隔操作装置 |
| TWI268930B (en) * | 2000-07-28 | 2006-12-21 | Ing-Jun Chen | Theophylline and 3-isobutyl-1-methylxanthine based N-7 substituted derivatives and pharmaceutical composition thereof |
| RU2333212C3 (ru) * | 2007-03-29 | 2019-08-26 | Общество С Ограниченной Ответственностью "Фармвинг" | ПРОИЗВОДНЫЕ 1-И 7-[ω-(БЕНЗГИДРИЛ-4-ПИПЕРАЗИНИЛ-1)АЛКИЛ]-3-АЛКИЛКСАНТИНОВ, ОБЛАДАЮЩИЕ ПРОТИВОГИСТАМИННОЙ И АНТИАЛЛЕРГИЧЕСКОЙ АКТИВНОСТЬЮ |
| PT2159226T (pt) * | 2007-03-29 | 2016-12-16 | Joint-Stock Company Obninsk Chemical Pharmaceutical Company | Agente anti-histamínico e antialérgico e um método para a produção do mesmo |
| US20230349922A1 (en) | 2020-08-11 | 2023-11-02 | Université De Strasbourg | H2 Blockers Targeting Liver Macrophages for the Prevention and Treatment of Liver Disease and Cancer |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1133989A (en) * | 1964-12-08 | 1968-11-20 | Chugai Pharmaceutical Co Ltd | Theophylline derivatives, their salts and process for preparing the same |
| DE1966620A1 (de) * | 1969-03-20 | 1973-05-24 | Walter Dr Bestian | Verfahren zur herstellung von dialkylxanthin-derivaten |
| GB1289287A (da) * | 1969-03-28 | 1972-09-13 | ||
| DE2550000A1 (de) * | 1975-11-07 | 1977-05-12 | Boehringer Mannheim Gmbh | Neue purin-derivate und verfahren zu ihrer herstellung |
| DE2922159A1 (de) * | 1979-05-31 | 1980-12-04 | Boehringer Mannheim Gmbh | Neue xanthin-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
| JPS5618983A (en) * | 1979-07-25 | 1981-02-23 | Eisai Co Ltd | Theophylline derivative and its preapration |
| CH648559A5 (de) * | 1981-07-20 | 1985-03-29 | Siegfried Ag | Theophyllinderivate und verfahren zu deren herstellung. |
| US4400381A (en) * | 1981-07-31 | 1983-08-23 | Laroche-Navarron, S.A. | Piperazine derivatives of theophylline |
| FR2531085A1 (fr) * | 1982-07-28 | 1984-02-03 | Adir | Nouveaux derives de la xanthine, leur procede de preparation et les compositions pharmaceutiques les renfermant |
| US4548939A (en) * | 1984-10-01 | 1985-10-22 | Janssen Pharmaceutica N. V. | 1H-Indol-3-yl containing 1,3-dimethyl-1H-purine-2,6-diones |
-
1981
- 1981-07-20 CH CH4739/81A patent/CH648559A5/de not_active IP Right Cessation
-
1982
- 1982-06-25 AT AT82105665T patent/ATE18047T1/de not_active IP Right Cessation
- 1982-06-25 DE DE8282105665T patent/DE3269160D1/de not_active Expired
- 1982-06-25 EP EP82105665A patent/EP0071738B1/de not_active Expired
- 1982-07-15 AU AU86048/82A patent/AU562299B2/en not_active Ceased
- 1982-07-16 FI FI822527A patent/FI78297C/fi not_active IP Right Cessation
- 1982-07-16 SU SU823464552A patent/SU1114337A3/ru active
- 1982-07-19 IE IE1728/82A patent/IE53583B1/en unknown
- 1982-07-19 GR GR68796A patent/GR76221B/el unknown
- 1982-07-19 ZA ZA825123A patent/ZA825123B/xx unknown
- 1982-07-19 DK DK322882A patent/DK148688C/da not_active Application Discontinuation
- 1982-07-19 KR KR8203195A patent/KR880001283B1/ko not_active Expired
- 1982-07-19 HU HU822338A patent/HU189160B/hu not_active IP Right Cessation
- 1982-07-20 CA CA000407600A patent/CA1202971A/en not_active Expired
- 1982-07-20 ES ES514169A patent/ES8304981A1/es not_active Expired
- 1982-07-20 PH PH27599A patent/PH19076A/en unknown
- 1982-07-20 WO PCT/EP1982/000155 patent/WO1987000841A1/en not_active Ceased
- 1982-07-20 JP JP57125208A patent/JPS5824585A/ja active Pending
-
1983
- 1983-03-11 US US06/474,230 patent/US4603204A/en not_active Expired - Fee Related
-
1985
- 1985-12-26 US US06/813,439 patent/US4668786A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP0071738A1 (de) | 1983-02-16 |
| ZA825123B (en) | 1983-05-25 |
| FI78297C (fi) | 1989-07-10 |
| SU1114337A3 (ru) | 1984-09-15 |
| PH19076A (en) | 1985-12-19 |
| KR840000548A (ko) | 1984-02-25 |
| US4668786A (en) | 1987-05-26 |
| IE821728L (en) | 1983-01-20 |
| WO1987000841A1 (en) | 1987-02-12 |
| ES514169A0 (es) | 1983-04-01 |
| KR880001283B1 (ko) | 1988-07-18 |
| FI78297B (fi) | 1989-03-31 |
| AU562299B2 (en) | 1987-06-04 |
| FI822527L (fi) | 1983-01-21 |
| DK148688B (da) | 1985-09-02 |
| HU189160B (en) | 1986-06-30 |
| EP0071738B1 (de) | 1986-02-19 |
| GR76221B (da) | 1984-08-04 |
| US4603204A (en) | 1986-07-29 |
| CA1202971A (en) | 1986-04-08 |
| CH648559A5 (de) | 1985-03-29 |
| DK322882A (da) | 1983-01-21 |
| IE53583B1 (en) | 1988-12-21 |
| AU8604882A (en) | 1983-01-27 |
| ES8304981A1 (es) | 1983-04-01 |
| DE3269160D1 (en) | 1986-03-27 |
| JPS5824585A (ja) | 1983-02-14 |
| ATE18047T1 (de) | 1986-03-15 |
| FI822527A0 (fi) | 1982-07-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AHS | Application shelved for other reasons than non-payment |