DK147318C - Analogifremgangsmaade til fremstilling af racemiske eller optisk aktive c-(2-benzofuranyl)-tetrahydropyridiner eller -piperidiner eller syreadditionssalte deraf - Google Patents

Analogifremgangsmaade til fremstilling af racemiske eller optisk aktive c-(2-benzofuranyl)-tetrahydropyridiner eller -piperidiner eller syreadditionssalte deraf

Info

Publication number
DK147318C
DK147318C DK110174A DK110174A DK147318C DK 147318 C DK147318 C DK 147318C DK 110174 A DK110174 A DK 110174A DK 110174 A DK110174 A DK 110174A DK 147318 C DK147318 C DK 147318C
Authority
DK
Denmark
Prior art keywords
tetrahydropyridines
piperidines
benzofuranyl
racemic
analogue
Prior art date
Application number
DK110174A
Other languages
Danish (da)
English (en)
Other versions
DK147318B (da
Inventor
Karl Schenker
Raymond Bernasconi
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Priority to DK283278A priority Critical patent/DK147051C/da
Publication of DK147318B publication Critical patent/DK147318B/da
Application granted granted Critical
Publication of DK147318C publication Critical patent/DK147318C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
    • C07D213/30—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
DK110174A 1973-03-02 1974-03-01 Analogifremgangsmaade til fremstilling af racemiske eller optisk aktive c-(2-benzofuranyl)-tetrahydropyridiner eller -piperidiner eller syreadditionssalte deraf DK147318C (da)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DK283278A DK147051C (da) 1973-03-02 1978-06-23 Analogifremgangsmaade til fremstilling af racemiske eller optisk aktive 4-(2-benzofuranyl)-tetrahydropyridiner eller -piperidiner eller syreadditionssalte deraf

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH310373A CH592656A5 (fr) 1973-03-02 1973-03-02
CH310373 1973-03-02

Publications (2)

Publication Number Publication Date
DK147318B DK147318B (da) 1984-06-18
DK147318C true DK147318C (da) 1984-12-24

Family

ID=4248678

Family Applications (1)

Application Number Title Priority Date Filing Date
DK110174A DK147318C (da) 1973-03-02 1974-03-01 Analogifremgangsmaade til fremstilling af racemiske eller optisk aktive c-(2-benzofuranyl)-tetrahydropyridiner eller -piperidiner eller syreadditionssalte deraf

Country Status (24)

Country Link
US (1) US4210655A (fr)
JP (2) JPS599557B2 (fr)
AR (4) AR205619A1 (fr)
AT (1) AT336014B (fr)
BE (1) BE811767A (fr)
CA (1) CA1045139A (fr)
CH (1) CH592656A5 (fr)
CS (5) CS176296B2 (fr)
DD (1) DD113007A5 (fr)
DE (1) DE2408476A1 (fr)
DK (1) DK147318C (fr)
ES (1) ES423711A1 (fr)
FR (1) FR2219781B1 (fr)
GB (1) GB1465581A (fr)
HU (1) HU172464B (fr)
IE (1) IE38907B1 (fr)
IL (1) IL44237A (fr)
LU (1) LU69510A1 (fr)
MX (1) MX3765E (fr)
NL (1) NL179206C (fr)
SE (1) SE410856B (fr)
SU (6) SU560531A3 (fr)
YU (2) YU52374A (fr)
ZA (1) ZA741362B (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH609054A5 (en) * 1975-11-26 1979-02-15 Ciba Geigy Ag Process for the preparation of a novel piperidine derivative
EP0006524A1 (fr) * 1978-06-22 1980-01-09 Ciba-Geigy Ag Dérivés de tétrahydropyridine et de tétrahydropipéridine, leurs sels d'addition acides, procédés pour leur préparation et compositions pharmaceutiques les contenant
US4284638A (en) * 1978-11-21 1981-08-18 Ciba-Geigy Corporation Pharmaceutical compositions with central depressant and antipsychotic activity having a butyrophenone derivative which is substituted in the 4-position and a C-(2-benzofuranyl)-piperidine or C-(2-benzofuranyl)-tetrahydro-pyridine
US5045551A (en) * 1989-09-19 1991-09-03 Allergan, Inc. Acetylenes disubstituted with a heteroaromatic group and a 2-substituted chromanyl, thiochromanyl or 1,2,3,4-tetrahydroquinolinyl group having retinoid-like activity
US5455254A (en) * 1991-02-15 1995-10-03 Mondadori; Cesare Substituted benzofuranylpiperidine as a nootropic agent
RU2095339C1 (ru) * 1991-10-17 1997-11-10 Циба-Гейги АГ Производные гидрохинона в свободном виде или в виде соли, способы их получения, производные пиперидина и способы их получения
WO1993016695A1 (fr) * 1992-02-21 1993-09-02 Ciba-Geigy Ag Utilisation de la brofaromine comme agent de traitement du stress post-traumatique
US5693807A (en) * 1992-10-14 1997-12-02 Ciba-Geigy Corporation Substituted hydroquinone derivatives
EP0637586B1 (fr) * 1993-08-05 1999-06-02 HOECHST MARION ROUSSEL, Inc. Dérivés de 2-(pipéridin-4-yl, pyridin-4-yl et tétrahydropyridin-4-yl)-benzofuran-7-carbamate, leur préparation et leur utilisation comme inhibiteurs d'acetylcholinesterase
GB9605065D0 (en) * 1996-03-11 1996-05-08 Merck Sharp & Dohme Therapeutic agents
AU5319700A (en) 1999-06-02 2000-12-18 S. Mbua Ngale Efange Nicotine receptor ligands
WO2011162364A1 (fr) 2010-06-23 2011-12-29 住友化学株式会社 Composition de lutte contre les arthropodes nuisibles et composé hétérocyclique

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1041525A (en) * 1964-11-11 1966-09-07 Belge Produits Chimiques Sa Benzofuran derivatives and processes for preparing the same
FR1461633A (fr) * 1964-11-11 1966-02-25 Belge Produits Chimiques Sa Nouveaux dérivés benzofuranniques, leurs sels et procédés de préparation de cesdérivés et de leurs sels
IE39264B1 (en) * 1973-05-25 1978-08-30 Ciba Geigy Ag New pharmaceutical preparations

Also Published As

Publication number Publication date
DE2408476A1 (de) 1974-09-12
DK147318B (da) 1984-06-18
SU646911A4 (ru) 1979-02-05
YU52374A (en) 1982-06-18
SU651702A3 (ru) 1979-03-05
ES423711A1 (es) 1977-01-16
IL44237A (en) 1977-08-31
NL179206C (nl) 1986-08-01
FR2219781B1 (fr) 1977-07-01
FR2219781A1 (fr) 1974-09-27
AT336014B (de) 1977-04-12
AR211860A1 (es) 1978-03-31
SU651703A3 (ru) 1979-03-05
AR210858A1 (es) 1977-09-30
CS176299B2 (fr) 1977-06-30
JPS599557B2 (ja) 1984-03-03
BE811767A (fr) 1974-09-02
US4210655A (en) 1980-07-01
SU649321A3 (ru) 1979-02-25
CS176296B2 (fr) 1977-06-30
AU6619274A (en) 1975-09-04
JPS584781A (ja) 1983-01-11
IE38907L (en) 1974-09-02
DE2408476C2 (fr) 1990-12-06
CS176298B2 (fr) 1977-06-30
NL7402755A (fr) 1974-09-04
IL44237A0 (en) 1974-05-16
CH592656A5 (fr) 1977-10-31
SU612630A3 (ru) 1978-06-25
LU69510A1 (fr) 1975-12-09
YU37163B (fr) 1984-08-31
SE410856B (sv) 1979-11-12
GB1465581A (en) 1977-02-23
SU560531A3 (ru) 1977-05-30
IE38907B1 (en) 1978-06-21
CA1045139A (fr) 1978-12-26
YU212380A (en) 1983-04-27
CS176297B2 (fr) 1977-06-30
JPS49117474A (fr) 1974-11-09
HU172464B (hu) 1978-09-28
JPS6046115B2 (ja) 1985-10-14
AR208554A1 (es) 1977-02-15
CS176266B2 (fr) 1977-06-30
ATA170674A (de) 1976-08-15
DD113007A5 (fr) 1975-05-12
MX3765E (es) 1981-06-25
ZA741362B (en) 1975-01-29
AR205619A1 (es) 1976-05-21

Similar Documents

Publication Publication Date Title
DK136904B (da) Analogifremgangsmade til fremstilling af racemiske eller optisk aktive 2-(heteroarylmethyl)-5,9beta-dialkyl-6,7-benzomorphaner eller syreadditionssalte deraf
DK142750C (da) Analogifremgangsmaade til fremstilling af racemiske eller optisk aktive dopaminderivater eller syreadditionssalte deraf
DK143128C (da) Analogifremgangsmaade til fremstilling af 1-aryloxy-2-hydroxy-3-alkynylaminopropaner eller deres fysiologisk acceptable syreadditionssalte
DK140281B (da) Analogifremgangsmåde til fremstilling af racemiske eller optisk aktive 1-phenoxy-2-hydroxy-3-cycloalkylaminopropaner eller syreadditionssalte heraf.
DK136527B (da) Analogifremgangsmåde til fremstilling af racemiske eller optisk aktive p-alkoxyfenoxypropanolaminer eller syreadditionssalte deraf.
DK147318C (da) Analogifremgangsmaade til fremstilling af racemiske eller optisk aktive c-(2-benzofuranyl)-tetrahydropyridiner eller -piperidiner eller syreadditionssalte deraf
DK125021B (da) Analogifremgangsmåde til fremstilling af 1,2,3,4-tetrahydro-4-phenyl-isoquinolinderivater eller syreadditionssalte deraf eller de tilsvarende optisk aktive forbindelser.
DK137234B (da) Analogifremgangsmåde til fremstilling af racemisk eller optisk aktiv 1-isopropylamino-3-(4-(2-isopropylkarbamoylaminoætyl)-fenoxy)-propanol-2 eller syreadditionssalte deraf.
DK144094C (da) Analogifremgangsmaade til fremstilling af n-substituerede 3-hydroxy-8-oxamorphinaner eller syreadditionssalte deraf
DK129127B (da) Analogifremgangsmåde til fremstilling af racemiske eller optisk aktive 2-(furylmethyl)-6,7-benzomorphaner eller deres syreadditionssalte.
DK145574C (da) Analogifremgangsmaade til fremstilling af substituerede cyclopropylalkylaminer eller syreadditionssalte deraf
DK143445C (da) Analogifremgangsmaade til fremstilling af racemiske eller optisk aktive substituerede 1,1-diphenyl-3-amino-propanol-forbindelser
DK141875C (da) Analogifremgangsmaade til fremstilling af normorphinonderivater eller syreadditionssalte deraf
DK125639B (da) Analogifremgangsmåde til fremstilling af racemisk eller optisk aktivt 1-(2-nitrilophenoxy)-2-hydroxy-3-ethylaminopropan eller syreadditionssalte heraf.
DK139582B (da) Analogifremgangsmåde til fremstilling af racemiske eller optisk aktive benzocycloheptaisoquinolin-forbindelser eller syreadditionssalte deraf.
DK138491B (da) Analogifremgangsmåde til fremstilling af N-(1-cyclohexyl-3-pyrrolidinyl)-benzamider eller syreadditionssalte deraf.
DK137085B (da) Analogifremgangsmåde til fremstilling af cycloalkyl-alkyl-estere af vincaminsyrederivater eller syreadditionssalte deraf.
DK133980C (da) Analogifremgangsmade til fremstilling af racemiske eller optisk aktive diphenylalkyllactamimidderivater eller syreadditionssalte deraf
DK130958B (da) Analogifremgangsmåde til fremstilling af racemiske eller optisk aktive 1-phenoxy-2-hydroxy-3-hydroxyalkylaminopropaner eller fysiologisk tålelige syreadditionssalte heraf.
DK145576C (da) Analogifremgangsmaade til fremstilling af 6-fluor-substituerede thioxanthener eller syreadditionssalte deraf
DK143197C (da) Analogifremgangsmaade til fremstilling af 5,7-dihydroxy-tetrahydroisoquinoliner eller farmaceutisk acceptable syreadditionssalte deraf
DK133555C (da) Analogifremgangsmade til fremstilling af racemiske eller optisk aktive n-thienylmethyl-heterocycliske forbindelser eller syreadditionssalte deraf
DK123102B (da) Analogifremgangsmåde til fremstilling af racemiske eller optisk aktive benzo[b]thiopheneddikesyreforbindelser eller carboxylatsalte deraf.
DK140408C (da) Analogifremgangsmaade til fremstilling af n-(heteroarylmethyl)-7alfa-acyl-6,14-endoetheno- eller -endoethano-tetrahydronororipaviner eller-thebainer eller syreadditionssalte deraf
DK129699B (da) Analogifremgangsmåde til fremstilling af racemiske eller optisk aktive 9,10-dihydro-9,10-ethano-anthracener eller syreadditionssalte deraf.

Legal Events

Date Code Title Description
PUP Patent expired