DK1434622T3 - Anordninger til frigörelse af lægemidler ved transpalpebral iontoforese - Google Patents
Anordninger til frigörelse af lægemidler ved transpalpebral iontoforeseInfo
- Publication number
- DK1434622T3 DK1434622T3 DK02790508T DK02790508T DK1434622T3 DK 1434622 T3 DK1434622 T3 DK 1434622T3 DK 02790508 T DK02790508 T DK 02790508T DK 02790508 T DK02790508 T DK 02790508T DK 1434622 T3 DK1434622 T3 DK 1434622T3
- Authority
- DK
- Denmark
- Prior art keywords
- devices
- releasing drugs
- transpalpebral
- iontophoresis
- transpalpebral iontophoresis
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
- A61F9/0017—Introducing ophthalmic products into the ocular cavity or retaining products therein implantable in, or in contact with, the eye, e.g. ocular inserts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/20—Applying electric currents by contact electrodes continuous direct currents
- A61N1/30—Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/0404—Electrodes for external use
- A61N1/0408—Use-related aspects
- A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
- A61N1/0432—Anode and cathode
- A61N1/0436—Material of the electrode
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/0404—Electrodes for external use
- A61N1/0408—Use-related aspects
- A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
- A61N1/0432—Anode and cathode
- A61N1/044—Shape of the electrode
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/0404—Electrodes for external use
- A61N1/0408—Use-related aspects
- A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
- A61N1/0448—Drug reservoir
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/325—Applying electric currents by contact electrodes alternating or intermittent currents for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/0404—Electrodes for external use
- A61N1/0408—Use-related aspects
- A61N1/0412—Specially adapted for transcutaneous electroporation, e.g. including drug reservoirs
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Ophthalmology & Optometry (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Electrotherapy Devices (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0113176A FR2830766B1 (fr) | 2001-10-12 | 2001-10-12 | Dispositif de delivrance de medicaments par iontophorese transpalpebrale |
PCT/FR2002/003472 WO2003030989A2 (fr) | 2001-10-12 | 2002-10-11 | Dispositif de delivrance de medicaments par iontophorese transpalpebrale |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1434622T3 true DK1434622T3 (da) | 2007-08-13 |
Family
ID=8868226
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK02790508T DK1434622T3 (da) | 2001-10-12 | 2002-10-11 | Anordninger til frigörelse af lægemidler ved transpalpebral iontoforese |
Country Status (16)
Country | Link |
---|---|
US (3) | US7848800B2 (ko) |
EP (1) | EP1434622B1 (ko) |
JP (1) | JP4184275B2 (ko) |
KR (1) | KR20050035158A (ko) |
AT (1) | ATE358510T1 (ko) |
BR (1) | BR0213249A (ko) |
CA (1) | CA2463362C (ko) |
CY (1) | CY1106671T1 (ko) |
DE (1) | DE60219336T2 (ko) |
DK (1) | DK1434622T3 (ko) |
ES (1) | ES2283628T3 (ko) |
FR (1) | FR2830766B1 (ko) |
IL (1) | IL161298A0 (ko) |
MX (1) | MXPA04003438A (ko) |
PT (1) | PT1434622E (ko) |
WO (1) | WO2003030989A2 (ko) |
Families Citing this family (43)
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---|---|---|---|---|
US7431710B2 (en) | 2002-04-08 | 2008-10-07 | Glaukos Corporation | Ocular implants with anchors and methods thereof |
US20090088721A1 (en) * | 2001-04-17 | 2009-04-02 | Eyegate Pharma S.A.S. | Enhanced retinal delivery of a nucleic acid through iontophoresis |
US9994853B2 (en) | 2001-05-18 | 2018-06-12 | Sirna Therapeutics, Inc. | Chemically modified multifunctional short interfering nucleic acid molecules that mediate RNA interference |
US9181551B2 (en) | 2002-02-20 | 2015-11-10 | Sirna Therapeutics, Inc. | RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA) |
US9657294B2 (en) | 2002-02-20 | 2017-05-23 | Sirna Therapeutics, Inc. | RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA) |
FR2869531B1 (fr) * | 2004-04-30 | 2006-07-14 | Optis France Sa Sa | Dispositif de iontophorese oculaire diminuant les irritations |
BRPI0509334A (pt) | 2004-04-30 | 2007-10-16 | Eyegate Pharma S A | dispositivo de iontoforese ocular, que diminui as irritações |
US10508277B2 (en) | 2004-05-24 | 2019-12-17 | Sirna Therapeutics, Inc. | Chemically modified multifunctional short interfering nucleic acid molecules that mediate RNA interference |
US8246949B2 (en) | 2004-10-27 | 2012-08-21 | Aciont, Inc. | Methods and devices for sustained in-vivo release of an active agent |
US8755880B2 (en) | 2005-10-24 | 2014-06-17 | Aciont, Inc. | Intraocular iontophoretic device and associated methods |
US20070260171A1 (en) * | 2005-09-27 | 2007-11-08 | Higuchi John W | Intraocular iontophoretic device and associated methods |
US8634907B2 (en) | 2005-10-24 | 2014-01-21 | Aciont, Inc. | Intraocular iontophoretic device and associated methods |
JP5128932B2 (ja) * | 2007-12-28 | 2013-01-23 | 日立マクセル株式会社 | 美容機器 |
CN102341146B (zh) | 2008-12-31 | 2015-09-23 | 艾盖茨药品公司 | 具有缓冲的眼用离子电渗用体系和方法 |
EP2408458A1 (en) | 2009-03-19 | 2012-01-25 | Merck Sharp&Dohme Corp. | RNA INTERFERENCE MEDIATED INHIBITION OF SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION 6 (STAT6) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA) |
US20120016010A1 (en) | 2009-03-19 | 2012-01-19 | Merck Sharp & Dohme Corp | RNA Interference Mediated Inhibition of BTB and CNC Homology 1, Basic Leucine Zipper Transcription Factor 1 (BACH1) Gene Expression Using Short Interfering Nucleic Acid (siNA) |
JP2012520685A (ja) | 2009-03-19 | 2012-09-10 | メルク・シャープ・エンド・ドーム・コーポレイション | 低分子干渉核酸(siNA)を用いたGATA結合タンパク質3(GATA3)遺伝子発現のRNA干渉媒介性阻害 |
WO2010107952A2 (en) | 2009-03-19 | 2010-09-23 | Merck Sharp & Dohme Corp. | RNA INTERFERENCE MEDIATED INHIBITION OF CONNECTIVE TISSUE GROWTH FACTOR (CTGF) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA) |
US20120004281A1 (en) | 2009-03-27 | 2012-01-05 | Merck Sharp & Dohme Corp | RNA Interference Mediated Inhibition of the Nerve Growth Factor Beta Chain (NGFB) Gene Expression Using Short Interfering Nucleic Acid (siNA) |
EP2411516A1 (en) | 2009-03-27 | 2012-02-01 | Merck Sharp&Dohme Corp. | RNA INTERFERENCE MEDIATED INHIBITION OF APOPTOSIS SIGNAL-REGULATING KINASE 1 (ASK1) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA) |
US20120022142A1 (en) | 2009-03-27 | 2012-01-26 | Merck Sharp & Dohme Corp. | RNA Interference Mediated Inhibition of Signal Transducer and Activator of Transcription 1 (STAT1) Gene Expression Using Short Interfering Nucleic Acid (siNA) |
EP2411517A2 (en) | 2009-03-27 | 2012-02-01 | Merck Sharp&Dohme Corp. | RNA INTERFERENCE MEDIATED INHIBITION OF THE INTERCELLULAR ADHESION MOLECULE 1 (ICAM-1)GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA) |
EP2411520A2 (en) | 2009-03-27 | 2012-02-01 | Merck Sharp&Dohme Corp. | RNA INTERFERENCE MEDIATED INHIBITION OF THE THYMIC STROMAL LYMPHOPOIETIN (TSLP) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA) |
US10206813B2 (en) | 2009-05-18 | 2019-02-19 | Dose Medical Corporation | Implants with controlled drug delivery features and methods of using same |
JP2011018873A (ja) * | 2009-05-22 | 2011-01-27 | Sony Ericsson Mobilecommunications Japan Inc | 電磁シールド方法および電磁シールド用フィルム |
US20130150304A1 (en) | 2010-07-09 | 2013-06-13 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Treatment of a disease associated with retinal degenerative disorder |
CN103068980B (zh) | 2010-08-02 | 2017-04-05 | 瑟纳治疗公司 | 使用短干扰核酸(siNA)的RNA干扰介导的联蛋白(钙粘蛋白关联蛋白质),β1(CTNNB1)基因表达的抑制 |
SI2606134T1 (sl) | 2010-08-17 | 2019-08-30 | Sirna Therapeutics, Inc. | RNA-INTERFERENČNO POSREDOVANO ZAVIRANJE IZRAŽANJA GENA VIRUSA HEPATITISA B (HBV) Z UPORABO KRATKE INTERFERENČNE NUKLEINSKE KISLINE (siNA) |
WO2012027467A1 (en) | 2010-08-26 | 2012-03-01 | Merck Sharp & Dohme Corp. | RNA INTERFERENCE MEDIATED INHIBITION OF PROLYL HYDROXYLASE DOMAIN 2 (PHD2) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA) |
DK2632472T3 (en) | 2010-10-29 | 2018-03-19 | Sirna Therapeutics Inc | RNA INTERFERENCE-MEDIATED INHIBITION OF GENE EXPRESSION USING SHORT INTERFERRING NUCLEIC ACIDS (SINA) |
US10245178B1 (en) | 2011-06-07 | 2019-04-02 | Glaukos Corporation | Anterior chamber drug-eluting ocular implant |
EP3919620A1 (en) | 2012-05-02 | 2021-12-08 | Sirna Therapeutics, Inc. | Short interfering nucleic acid (sina) compositions |
RU2015126856A (ru) | 2012-12-06 | 2017-01-13 | Мерк Шарп И Доум Корп. | Дисульфидные маскированные пролекарственные композиции и способы |
EP3148491B1 (en) | 2014-05-29 | 2020-07-01 | Glaukos Corporation | Implants with controlled drug delivery features and manufacturing method for said implants |
US9937074B2 (en) | 2015-01-22 | 2018-04-10 | Eyegate Pharmaceuticals, Inc. | Iontophoretic contact lens |
EP3297679A1 (en) | 2015-05-20 | 2018-03-28 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Treatment of retinal detachment |
US11925578B2 (en) | 2015-09-02 | 2024-03-12 | Glaukos Corporation | Drug delivery implants with bi-directional delivery capacity |
WO2017053885A1 (en) | 2015-09-25 | 2017-03-30 | Glaukos Corporation | Punctal implants with controlled drug delivery features and methods of using same |
EP3442479A1 (en) | 2016-04-20 | 2019-02-20 | Harold Alexander Heitzmann | Bioresorbable ocular drug delivery device |
KR20190093214A (ko) | 2016-12-13 | 2019-08-08 | 베타 테라퓨틱스 피티와이 리미티드 | 헤파라나제 억제제 및 그의 용도 |
US11787783B2 (en) | 2016-12-13 | 2023-10-17 | Beta Therapeutics Pty Ltd | Heparanase inhibitors and use thereof |
IT201700014315A1 (it) * | 2017-02-09 | 2018-08-09 | Bruno Massimo Cetroni | Dispositivo per il trasporto intracellulare in biorisonanza |
KR101889357B1 (ko) * | 2017-09-20 | 2018-08-17 | (주)휴비딕 | 눈의 나노 약물 전달용 이온공급 장치 |
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US3845757A (en) * | 1972-07-12 | 1974-11-05 | Minnesota Mining & Mfg | Biomedical monitoring electrode |
US4564016A (en) * | 1982-05-24 | 1986-01-14 | The Board Of Trustees Of The Leland Stanford Junior University | Apparatus for introducing ionized drugs into the posterior segment of the eye and method |
US4603076A (en) * | 1985-03-04 | 1986-07-29 | Norwood Industries, Inc. | Hydrophilic foam |
US5320597A (en) * | 1991-02-08 | 1994-06-14 | Becton, Dickinson And Company | Device and method for renewing electrodes during iontophoresis |
US5169384A (en) * | 1991-08-16 | 1992-12-08 | Bosniak Stephen L | Apparatus for facilitating post-traumatic, post-surgical, and/or post-inflammatory healing of tissue |
US5356632A (en) * | 1991-09-12 | 1994-10-18 | S.I. Scientific Innovations Ltd. | Transdermal drug delivery device |
AU652494B2 (en) * | 1991-11-15 | 1994-08-25 | Minnesota Mining And Manufacturing Company | Solid state conductive polymer compositions, biomedical electrodes containing such compositions, and method of preparing same |
US5450845A (en) * | 1993-01-11 | 1995-09-19 | Axelgaard; Jens | Medical electrode system |
US5522864A (en) * | 1994-10-25 | 1996-06-04 | Wallace; Larry B. | Apparatus and method for ocular treatment |
AUPM982694A0 (en) * | 1994-12-02 | 1995-01-05 | University Of Queensland, The | Iontophoresis method and apparatus |
FR2773320B1 (fr) * | 1998-01-05 | 2000-03-03 | Optisinvest | Dispositif pour le transfert intraoculaire de produits actifs par iontophorese |
IL123290A (en) * | 1998-02-13 | 2001-12-23 | Hadasit Med Res Service | Iontophoretic device |
US6503231B1 (en) * | 1998-06-10 | 2003-01-07 | Georgia Tech Research Corporation | Microneedle device for transport of molecules across tissue |
US6477410B1 (en) * | 2000-05-31 | 2002-11-05 | Biophoretic Therapeutic Systems, Llc | Electrokinetic delivery of medicaments |
US6277401B1 (en) * | 1999-05-07 | 2001-08-21 | U.S. Dermatologics, Inc. | Drug delivery device |
US6728573B1 (en) * | 2000-02-23 | 2004-04-27 | Iomed, Inc. | Ocular iontophoretic apparatus handle |
US6546284B2 (en) * | 2001-01-25 | 2003-04-08 | Iomed, Inc. | Fluid retention assembly for an iontophoretic delivery device and associated method for preparing the same |
US6697668B2 (en) * | 2001-01-25 | 2004-02-24 | Iomed, Inc. | Ocular iontophoretic device and method for using the same |
US20040106965A1 (en) * | 2001-06-29 | 2004-06-03 | Chow Alan Y. | Methods and apparatus for treatment of degenerative retinal disease via indirect electrical stimulation |
US20030023228A1 (en) * | 2001-07-20 | 2003-01-30 | Parkinson Thomas M. | Ocular iontophoretic device and method for using the same |
US6694193B2 (en) * | 2001-09-14 | 2004-02-17 | Koninklijke Philips Electronics N.V. | Medical electrode and release liner configurations facilitating packaged electrode characterization |
-
2001
- 2001-10-12 FR FR0113176A patent/FR2830766B1/fr not_active Expired - Fee Related
-
2002
- 2002-10-11 ES ES02790508T patent/ES2283628T3/es not_active Expired - Lifetime
- 2002-10-11 IL IL16129802A patent/IL161298A0/xx unknown
- 2002-10-11 EP EP02790508A patent/EP1434622B1/fr not_active Expired - Lifetime
- 2002-10-11 US US10/492,494 patent/US7848800B2/en not_active Expired - Fee Related
- 2002-10-11 DE DE60219336T patent/DE60219336T2/de not_active Expired - Lifetime
- 2002-10-11 PT PT02790508T patent/PT1434622E/pt unknown
- 2002-10-11 JP JP2003534018A patent/JP4184275B2/ja not_active Expired - Fee Related
- 2002-10-11 DK DK02790508T patent/DK1434622T3/da active
- 2002-10-11 AT AT02790508T patent/ATE358510T1/de not_active IP Right Cessation
- 2002-10-11 BR BR0213249-4A patent/BR0213249A/pt not_active Application Discontinuation
- 2002-10-11 CA CA2463362A patent/CA2463362C/fr not_active Expired - Fee Related
- 2002-10-11 MX MXPA04003438A patent/MXPA04003438A/es active IP Right Grant
- 2002-10-11 WO PCT/FR2002/003472 patent/WO2003030989A2/fr active IP Right Grant
- 2002-10-11 KR KR1020047005390A patent/KR20050035158A/ko not_active Application Discontinuation
-
2007
- 2007-06-21 CY CY20071100830T patent/CY1106671T1/el unknown
-
2010
- 2010-10-27 US US12/913,065 patent/US8771256B2/en not_active Expired - Fee Related
-
2014
- 2014-05-23 US US14/286,544 patent/US9192512B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
JP4184275B2 (ja) | 2008-11-19 |
IL161298A0 (en) | 2004-09-27 |
DE60219336T2 (de) | 2007-12-20 |
ES2283628T3 (es) | 2007-11-01 |
US20040267188A1 (en) | 2004-12-30 |
WO2003030989A3 (fr) | 2003-10-30 |
BR0213249A (pt) | 2004-09-28 |
FR2830766B1 (fr) | 2004-03-12 |
US9192512B2 (en) | 2015-11-24 |
US8771256B2 (en) | 2014-07-08 |
CY1106671T1 (el) | 2012-05-23 |
CA2463362C (fr) | 2011-04-19 |
US20140323947A1 (en) | 2014-10-30 |
CA2463362A1 (fr) | 2003-04-17 |
US7848800B2 (en) | 2010-12-07 |
ATE358510T1 (de) | 2007-04-15 |
MXPA04003438A (es) | 2005-02-17 |
WO2003030989A2 (fr) | 2003-04-17 |
US20110098632A1 (en) | 2011-04-28 |
EP1434622B1 (fr) | 2007-04-04 |
EP1434622A2 (fr) | 2004-07-07 |
DE60219336D1 (de) | 2007-05-16 |
FR2830766A1 (fr) | 2003-04-18 |
KR20050035158A (ko) | 2005-04-15 |
JP2005504612A (ja) | 2005-02-17 |
PT1434622E (pt) | 2007-07-11 |
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