ATE358510T1 - Vorrichtung zur iontophoretischen verabreichung von medikamenten durch das augenlid - Google Patents

Vorrichtung zur iontophoretischen verabreichung von medikamenten durch das augenlid

Info

Publication number
ATE358510T1
ATE358510T1 AT02790508T AT02790508T ATE358510T1 AT E358510 T1 ATE358510 T1 AT E358510T1 AT 02790508 T AT02790508 T AT 02790508T AT 02790508 T AT02790508 T AT 02790508T AT E358510 T1 ATE358510 T1 AT E358510T1
Authority
AT
Austria
Prior art keywords
eyelid
medication
iontophoretic administration
designed
main electrode
Prior art date
Application number
AT02790508T
Other languages
English (en)
Inventor
Francine Behar
Pierre Roy
Original Assignee
Eyegate Pharma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eyegate Pharma Sa filed Critical Eyegate Pharma Sa
Application granted granted Critical
Publication of ATE358510T1 publication Critical patent/ATE358510T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/20Applying electric currents by contact electrodes continuous direct currents
    • A61N1/30Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/0008Introducing ophthalmic products into the ocular cavity or retaining products therein
    • A61F9/0017Introducing ophthalmic products into the ocular cavity or retaining products therein implantable in, or in contact with, the eye, e.g. ocular inserts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/0404Electrodes for external use
    • A61N1/0408Use-related aspects
    • A61N1/0428Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0432Anode and cathode
    • A61N1/0436Material of the electrode
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/0404Electrodes for external use
    • A61N1/0408Use-related aspects
    • A61N1/0428Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0432Anode and cathode
    • A61N1/044Shape of the electrode
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/0404Electrodes for external use
    • A61N1/0408Use-related aspects
    • A61N1/0428Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0448Drug reservoir
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/325Applying electric currents by contact electrodes alternating or intermittent currents for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/0404Electrodes for external use
    • A61N1/0408Use-related aspects
    • A61N1/0412Specially adapted for transcutaneous electroporation, e.g. including drug reservoirs

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Electrotherapy Devices (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT02790508T 2001-10-12 2002-10-11 Vorrichtung zur iontophoretischen verabreichung von medikamenten durch das augenlid ATE358510T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0113176A FR2830766B1 (fr) 2001-10-12 2001-10-12 Dispositif de delivrance de medicaments par iontophorese transpalpebrale

Publications (1)

Publication Number Publication Date
ATE358510T1 true ATE358510T1 (de) 2007-04-15

Family

ID=8868226

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02790508T ATE358510T1 (de) 2001-10-12 2002-10-11 Vorrichtung zur iontophoretischen verabreichung von medikamenten durch das augenlid

Country Status (16)

Country Link
US (3) US7848800B2 (de)
EP (1) EP1434622B1 (de)
JP (1) JP4184275B2 (de)
KR (1) KR20050035158A (de)
AT (1) ATE358510T1 (de)
BR (1) BR0213249A (de)
CA (1) CA2463362C (de)
CY (1) CY1106671T1 (de)
DE (1) DE60219336T2 (de)
DK (1) DK1434622T3 (de)
ES (1) ES2283628T3 (de)
FR (1) FR2830766B1 (de)
IL (1) IL161298A0 (de)
MX (1) MXPA04003438A (de)
PT (1) PT1434622E (de)
WO (1) WO2003030989A2 (de)

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US9657294B2 (en) 2002-02-20 2017-05-23 Sirna Therapeutics, Inc. RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)
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US10508277B2 (en) 2004-05-24 2019-12-17 Sirna Therapeutics, Inc. Chemically modified multifunctional short interfering nucleic acid molecules that mediate RNA interference
US8246949B2 (en) * 2004-10-27 2012-08-21 Aciont, Inc. Methods and devices for sustained in-vivo release of an active agent
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US8755880B2 (en) * 2005-10-24 2014-06-17 Aciont, Inc. Intraocular iontophoretic device and associated methods
US8634907B2 (en) * 2005-10-24 2014-01-21 Aciont, Inc. Intraocular iontophoretic device and associated methods
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EP2408916A2 (de) 2009-03-19 2012-01-25 Merck Sharp&Dohme Corp. Rna-interferenz-vermittelte hemmung der genexpression von ctgf (connective tissue growth factor) unter verwendung von sina (short interfering nucleic acid)
WO2010107957A2 (en) 2009-03-19 2010-09-23 Merck Sharp & Dohme Corp. RNA INTERFERENCE MEDIATED INHIBITION OF GATA BINDING PROTEIN 3 (GATA3) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
CA2755773A1 (en) 2009-03-19 2010-09-23 Merck Sharp & Dohme Corp. Rna interference mediated inhibition of btb and cnc homology 1, basic leucine zipper transcription factor 1 (bach 1) gene expression using short interfering nucleic acid (sina)
WO2010111464A1 (en) 2009-03-27 2010-09-30 Merck Sharp & Dohme Corp. RNA INTERFERENCE MEDIATED INHIBITION OF APOPTOSIS SIGNAL-REGULATING KINASE 1 (ASK1) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
JP2012521762A (ja) 2009-03-27 2012-09-20 メルク・シャープ・エンド・ドーム・コーポレイション 低分子干渉核酸(siNA)を用いた神経成長因子β鎖(NGFβ)遺伝子発現のRNA干渉媒介性阻害
EP2411520A2 (de) 2009-03-27 2012-02-01 Merck Sharp&Dohme Corp. Rna-interferenz-vermittelte hemmung der genexpression von tslp (thymic stromal lymphopoietin) unter verwendung von sina (short interfering nucleic acid)
SG174581A1 (en) 2009-03-27 2011-10-28 Merck Sharp & Dohme RNA INTERFERENCE MEDIATED INHIBITION OF THE INTERCELLULAR ADHESION MOLECULE 1 (ICAM-1)GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
EP2411019A2 (de) 2009-03-27 2012-02-01 Merck Sharp&Dohme Corp. Rna-interferenz-vermittelte hemmung der signal transducer and activator of transcription 1 (stat1) gen-expression mittels sina (short interfering nucleic acid)
US10206813B2 (en) 2009-05-18 2019-02-19 Dose Medical Corporation Implants with controlled drug delivery features and methods of using same
JP2011018873A (ja) * 2009-05-22 2011-01-27 Sony Ericsson Mobilecommunications Japan Inc 電磁シールド方法および電磁シールド用フィルム
EP2590669B1 (de) 2010-07-09 2016-08-31 INSERM (Institut National de la Santé et de la Recherche Médicale) Behandlung von krankheiten im zusammenhang mit degenerativen netzhautstörungen
US8518907B2 (en) 2010-08-02 2013-08-27 Merck Sharp & Dohme Corp. RNA interference mediated inhibition of catenin (cadherin-associated protein), beta 1 (CTNNB1) gene expression using short interfering nucleic acid (siNA)
EP2606134B1 (de) 2010-08-17 2019-04-10 Sirna Therapeutics, Inc. Rna-interferenz-vermittelte hemmung der hepatitis b-virus (hbv)-genexpression mittels kurzer interferierender nukleinsäure (sina)
EP2609106A4 (de) 2010-08-26 2014-03-19 Merck Sharp & Dohme Durch rna-interferenz vermittelte inhibition der prolyl-hydroxylase-domäne-2 (phd2)-genexpression unter verwendung von short-interfering-nukleinsäuren (sina)
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US10245178B1 (en) 2011-06-07 2019-04-02 Glaukos Corporation Anterior chamber drug-eluting ocular implant
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US9884886B2 (en) 2012-12-06 2018-02-06 Merck Sharp & Dohme Disulfide masked prodrug compositions and methods
EP3148491B1 (de) 2014-05-29 2020-07-01 Glaukos Corporation Implantate mit kontrollierter arzneimittelfreisetzung und herstellungsverfahren davon
US9937074B2 (en) 2015-01-22 2018-04-10 Eyegate Pharmaceuticals, Inc. Iontophoretic contact lens
US20180125947A1 (en) 2015-05-20 2018-05-10 INSERM (Institut National de la Santé et de la Recherche Médicale) Treatment of retinal detachment
WO2017040853A1 (en) 2015-09-02 2017-03-09 Glaukos Corporation Drug delivery implants with bi-directional delivery capacity
US11564833B2 (en) 2015-09-25 2023-01-31 Glaukos Corporation Punctal implants with controlled drug delivery features and methods of using same
CN115120405A (zh) 2016-04-20 2022-09-30 多斯医学公司 生物可吸收眼部药物的递送装置
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Also Published As

Publication number Publication date
ES2283628T3 (es) 2007-11-01
US7848800B2 (en) 2010-12-07
FR2830766B1 (fr) 2004-03-12
JP2005504612A (ja) 2005-02-17
US20040267188A1 (en) 2004-12-30
JP4184275B2 (ja) 2008-11-19
DE60219336D1 (de) 2007-05-16
EP1434622A2 (de) 2004-07-07
DK1434622T3 (da) 2007-08-13
IL161298A0 (en) 2004-09-27
US8771256B2 (en) 2014-07-08
MXPA04003438A (es) 2005-02-17
CY1106671T1 (el) 2012-05-23
CA2463362A1 (fr) 2003-04-17
BR0213249A (pt) 2004-09-28
US20140323947A1 (en) 2014-10-30
EP1434622B1 (de) 2007-04-04
US9192512B2 (en) 2015-11-24
US20110098632A1 (en) 2011-04-28
PT1434622E (pt) 2007-07-11
DE60219336T2 (de) 2007-12-20
KR20050035158A (ko) 2005-04-15
FR2830766A1 (fr) 2003-04-18
WO2003030989A2 (fr) 2003-04-17
WO2003030989A3 (fr) 2003-10-30
CA2463362C (fr) 2011-04-19

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