DK142681B - Analogifremgangsmåde til fremstilling af 3-oxo-androst-4-en-17-spirosultiner. - Google Patents

Analogifremgangsmåde til fremstilling af 3-oxo-androst-4-en-17-spirosultiner. Download PDF

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Publication number
DK142681B
DK142681B DK112277AA DK112277A DK142681B DK 142681 B DK142681 B DK 142681B DK 112277A A DK112277A A DK 112277AA DK 112277 A DK112277 A DK 112277A DK 142681 B DK142681 B DK 142681B
Authority
DK
Denmark
Prior art keywords
isomer
compound
ene
hydroxy
methyl
Prior art date
Application number
DK112277AA
Other languages
Danish (da)
English (en)
Other versions
DK142681C (no
DK112277A (no
Inventor
Vesperto Torelli
Genevieve Rousseau
Original Assignee
Roussel Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Publication of DK112277A publication Critical patent/DK112277A/da
Publication of DK142681B publication Critical patent/DK142681B/da
Application granted granted Critical
Publication of DK142681C publication Critical patent/DK142681C/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
    • C07J53/002—Carbocyclic rings fused
    • C07J53/004—3 membered carbocyclic rings
    • C07J53/007—3 membered carbocyclic rings in position 6-7
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J33/00—Normal steroids having a sulfur-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J33/005—Normal steroids having a sulfur-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton spiro-condensed

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  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
DK112277AA 1976-03-16 1977-03-15 Analogifremgangsmåde til fremstilling af 3-oxo-androst-4-en-17-spirosultiner. DK142681B (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR7607476A FR2344286A1 (fr) 1976-03-16 1976-03-16 Nouveaux derives 17-spirosultines, les g-hydroxy acides correspondants, leur procede de preparation et leur application comme medicament
FR7607476 1976-03-16

Publications (3)

Publication Number Publication Date
DK112277A DK112277A (no) 1977-09-17
DK142681B true DK142681B (da) 1980-12-15
DK142681C DK142681C (no) 1981-08-03

Family

ID=9170470

Family Applications (1)

Application Number Title Priority Date Filing Date
DK112277AA DK142681B (da) 1976-03-16 1977-03-15 Analogifremgangsmåde til fremstilling af 3-oxo-androst-4-en-17-spirosultiner.

Country Status (10)

Country Link
US (1) US4093720A (no)
JP (1) JPS52136156A (no)
BE (1) BE852457A (no)
CA (1) CA1096857A (no)
CH (1) CH619718A5 (no)
DE (1) DE2711516A1 (no)
DK (1) DK142681B (no)
FR (1) FR2344286A1 (no)
GB (1) GB1532734A (no)
NL (1) NL7702757A (no)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2569408B1 (fr) * 1984-08-24 1986-10-03 Roussel Uclaf Nouveaux steroides substitues en position 10 par un radical comportant une double ou triple liaison, leur procede de preparation, leur application comme medicaments, les compositions pharmaceutiques les renfermant
JPS63193059U (no) * 1987-05-30 1988-12-13
JPH02106265U (no) * 1989-02-10 1990-08-23
FR2681069B1 (fr) * 1991-09-06 1995-04-28 Roussel Uclaf Nouveau procede de preparation de l'hydrocortisone et nouveaux intermediaires.
US6043235A (en) * 1999-07-21 2000-03-28 Research Triangle Institute 11β-aryl-17, 17-spirothiolane-substituted steroids
CN116925169A (zh) * 2023-07-20 2023-10-24 浙江朗华制药有限公司 一种甾体化合物及其制备方法以及在坎利酮和螺内酯杂质研究中的应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DD80023A (no) *
DE2264189C3 (de) * 1972-12-29 1979-05-31 Merck & Co., Inc., Rahway, N.J. (V.St.A.) 3'-(3-Oxo-17beta-hydroxy-6,7-methylen-androst-4en-bzw.-l,4-dien-17 a-yl) -propionsäureverbindungen, Verfahren zu ihrer Herstellung sowie diese enthaltende pharmazeutische Mittel
FR2285137A1 (fr) * 1974-09-18 1976-04-16 Roussel Uclaf Nouveaux derives steroides 17-spirosultines, les g-hydroxyacides correspondants, leur procede de preparation et leur application comme medicament

Also Published As

Publication number Publication date
FR2344286B1 (no) 1978-11-17
BE852457A (fr) 1977-09-15
US4093720A (en) 1978-06-06
CA1096857A (fr) 1981-03-03
NL7702757A (nl) 1977-09-20
JPS6126557B2 (no) 1986-06-20
DK142681C (no) 1981-08-03
JPS52136156A (en) 1977-11-14
DE2711516A1 (de) 1977-09-22
DK112277A (no) 1977-09-17
CH619718A5 (no) 1980-10-15
DE2711516C2 (no) 1987-03-05
GB1532734A (en) 1978-11-22
FR2344286A1 (fr) 1977-10-14

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