DK142485A - Acyltripeptider, mellemprodukter ved deres fremstilling og farmaceutiske praeparater - Google Patents
Acyltripeptider, mellemprodukter ved deres fremstilling og farmaceutiske praeparater Download PDFInfo
- Publication number
- DK142485A DK142485A DK142485A DK142485A DK142485A DK 142485 A DK142485 A DK 142485A DK 142485 A DK142485 A DK 142485A DK 142485 A DK142485 A DK 142485A DK 142485 A DK142485 A DK 142485A
- Authority
- DK
- Denmark
- Prior art keywords
- acyltripeptides
- intermediates
- preparation
- pharmaceutical preparations
- preparations
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/36—Oxygen or sulfur atoms
- C07D207/40—2,5-Pyrrolidine-diones
- C07D207/404—2,5-Pyrrolidine-diones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms, e.g. succinimide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
- C07D313/16—Eight-membered rings
- C07D313/18—Eight-membered rings not condensed with other rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Communicable Diseases (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/595,169 US4565653A (en) | 1984-03-30 | 1984-03-30 | Acyltripeptide immunostimulants |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK142485D0 DK142485D0 (da) | 1985-03-29 |
| DK142485A true DK142485A (da) | 1985-10-01 |
Family
ID=24382038
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK142485A DK142485A (da) | 1984-03-30 | 1985-03-29 | Acyltripeptider, mellemprodukter ved deres fremstilling og farmaceutiske praeparater |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US4565653A (pm) |
| EP (1) | EP0157572A3 (pm) |
| JP (1) | JPS60224699A (pm) |
| KR (1) | KR870000372B1 (pm) |
| AU (2) | AU552919B2 (pm) |
| CA (1) | CA1270098A (pm) |
| DD (1) | DD239406A5 (pm) |
| DK (1) | DK142485A (pm) |
| EG (1) | EG17928A (pm) |
| ES (1) | ES8605821A1 (pm) |
| FI (1) | FI851271L (pm) |
| GR (1) | GR850783B (pm) |
| HU (1) | HU198086B (pm) |
| IL (1) | IL74758A (pm) |
| NO (1) | NO851278L (pm) |
| NZ (1) | NZ211634A (pm) |
| PH (1) | PH21303A (pm) |
| PL (1) | PL252659A1 (pm) |
| PT (1) | PT80181B (pm) |
| ZA (1) | ZA852335B (pm) |
Families Citing this family (59)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1295784C (en) * | 1985-11-25 | 1992-02-11 | James Patrick Rizzi | Peptide immunostimulants |
| JPH0718039B2 (ja) * | 1986-03-26 | 1995-03-01 | 株式会社豊田自動織機製作所 | 粉末付加亜鉛めっき鋼板の製造方法 |
| FI890885A7 (fi) * | 1986-08-27 | 1989-02-24 | Pfizer | Menetelmä N-(S-3-alkyyliheptanoyyli)-D-gamma-glutamyyli-glysyyli-D-ala niinin valmistamiseksi ja menetelmässä käyttökelpoiset välituotteet j a niiden valmistus |
| FI890886L (fi) * | 1986-08-27 | 1989-02-24 | Pfizer | Kristallin n-(s-3-metylheptanoyl) -d-gamma-glutamyl-glycyl-d-alanin och foerfaranden foer dess framstaellning samt mellanprodukter. |
| DE3700173A1 (de) * | 1987-01-05 | 1988-07-14 | Hoechst Ag | Verfahren zur herstellung von lipophilen aminosaeurederivaten sowie lipophile aminosaeurederivate |
| DE3820528A1 (de) * | 1988-06-16 | 1989-12-21 | Bayer Ag | Mittel zur insekten- und milbenabwehr |
| US5245079A (en) * | 1989-02-21 | 1993-09-14 | Pfizer Inc. | Processes and intermediates for N-(S-3-alkyl-heptanoyl)-D-gamma-glutamyl-glycyl-D-alanine |
| US5136020A (en) * | 1989-02-21 | 1992-08-04 | Pfizer Inc. | Crystalline n-(s-3-methylheptanoyl)-D-gamma-glutamyl-glycyl-D-alanine, and processes and intermediates therefor |
| US5248820A (en) * | 1989-02-21 | 1993-09-28 | Pfizer Inc. | Crystalline N-(S-3-methylheptanoyl)-D-gamma-glutamyl-glycyl-D-alanine, and processes and intermediates therefor |
| US5134225A (en) * | 1989-02-21 | 1992-07-28 | Pfizer Inc. | Processes and intermediates for N-(S-3-alkyl-heptanoyl)-D-gamma-glutamyl-D-alanine |
| US5185464A (en) * | 1989-02-21 | 1993-02-09 | Pfizer Inc. | Crystalline N-(S-3-methylheptanoyl)-D-gamma-glutamyl-glycyl-D-alanine, and processes and intermediates therefor |
| CA2125679C (en) | 1992-10-15 | 2005-06-28 | Ishizuka Masaaki | Novel amino acid derivatives |
| US5798387A (en) * | 1992-10-15 | 1998-08-25 | Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai | Amino acid derivatives |
| US5545553A (en) * | 1994-09-26 | 1996-08-13 | The Rockefeller University | Glycosyltransferases for biosynthesis of oligosaccharides, and genes encoding them |
| US7214660B2 (en) | 2001-10-10 | 2007-05-08 | Neose Technologies, Inc. | Erythropoietin: remodeling and glycoconjugation of erythropoietin |
| US7399613B2 (en) * | 2001-10-10 | 2008-07-15 | Neose Technologies, Inc. | Sialic acid nucleotide sugars |
| US7696163B2 (en) | 2001-10-10 | 2010-04-13 | Novo Nordisk A/S | Erythropoietin: remodeling and glycoconjugation of erythropoietin |
| US7795210B2 (en) * | 2001-10-10 | 2010-09-14 | Novo Nordisk A/S | Protein remodeling methods and proteins/peptides produced by the methods |
| US7173003B2 (en) * | 2001-10-10 | 2007-02-06 | Neose Technologies, Inc. | Granulocyte colony stimulating factor: remodeling and glycoconjugation of G-CSF |
| US7157277B2 (en) * | 2001-11-28 | 2007-01-02 | Neose Technologies, Inc. | Factor VIII remodeling and glycoconjugation of Factor VIII |
| US8008252B2 (en) * | 2001-10-10 | 2011-08-30 | Novo Nordisk A/S | Factor VII: remodeling and glycoconjugation of Factor VII |
| DE60336555D1 (de) * | 2002-06-21 | 2011-05-12 | Novo Nordisk Healthcare Ag | Pegylierte glykoformen von faktor vii |
| ES2420581T3 (es) * | 2003-03-14 | 2013-08-26 | Biogenerix Gmbh | Polímeros solubles en agua ramificados y sus conjugados |
| US8791070B2 (en) | 2003-04-09 | 2014-07-29 | Novo Nordisk A/S | Glycopegylated factor IX |
| EP2338333B1 (en) * | 2003-04-09 | 2017-09-06 | ratiopharm GmbH | Glycopegylation methods and proteins/peptides produced by the methods |
| US7691603B2 (en) * | 2003-04-09 | 2010-04-06 | Novo Nordisk A/S | Intracellular formation of peptide conjugates |
| CA2524936A1 (en) | 2003-05-09 | 2004-12-02 | Neose Technologies, Inc. | Compositions and methods for the preparation of human growth hormone glycosylation mutants |
| US9005625B2 (en) | 2003-07-25 | 2015-04-14 | Novo Nordisk A/S | Antibody toxin conjugates |
| MXPA06005732A (es) * | 2003-11-24 | 2006-08-17 | Neose Technologies Inc | Eritropoyetina glucopegilada. |
| US20080305992A1 (en) * | 2003-11-24 | 2008-12-11 | Neose Technologies, Inc. | Glycopegylated erythropoietin |
| US8633157B2 (en) * | 2003-11-24 | 2014-01-21 | Novo Nordisk A/S | Glycopegylated erythropoietin |
| US7956032B2 (en) * | 2003-12-03 | 2011-06-07 | Novo Nordisk A/S | Glycopegylated granulocyte colony stimulating factor |
| ES2422187T3 (es) * | 2003-12-03 | 2013-09-09 | Biogenerix Ag | Factor estimulante de colonias de granulocitos glicopegilados |
| US20060040856A1 (en) * | 2003-12-03 | 2006-02-23 | Neose Technologies, Inc. | Glycopegylated factor IX |
| US20080318850A1 (en) * | 2003-12-03 | 2008-12-25 | Neose Technologies, Inc. | Glycopegylated Factor Ix |
| ES2560657T3 (es) * | 2004-01-08 | 2016-02-22 | Ratiopharm Gmbh | Glicosilación con unión en O de péptidos G-CSF |
| WO2006010143A2 (en) | 2004-07-13 | 2006-01-26 | Neose Technologies, Inc. | Branched peg remodeling and glycosylation of glucagon-like peptide-1 [glp-1] |
| WO2006031811A2 (en) * | 2004-09-10 | 2006-03-23 | Neose Technologies, Inc. | Glycopegylated interferon alpha |
| EP3061461A1 (en) * | 2004-10-29 | 2016-08-31 | ratiopharm GmbH | Remodeling and glycopegylation of fibroblast growth factor (fgf) |
| WO2006074279A1 (en) * | 2005-01-06 | 2006-07-13 | Neose Technologies, Inc. | Glycoconjugation using saccharyl fragments |
| MX2007008229A (es) * | 2005-01-10 | 2007-09-11 | Neose Technologies Inc | Factor estimulador de colonias de granulocitos glicopegilado. |
| WO2006105426A2 (en) * | 2005-03-30 | 2006-10-05 | Neose Technologies, Inc. | Manufacturing process for the production of peptides grown in insect cell lines |
| US9187546B2 (en) * | 2005-04-08 | 2015-11-17 | Novo Nordisk A/S | Compositions and methods for the preparation of protease resistant human growth hormone glycosylation mutants |
| WO2006127910A2 (en) * | 2005-05-25 | 2006-11-30 | Neose Technologies, Inc. | Glycopegylated erythropoietin formulations |
| US20080255026A1 (en) * | 2005-05-25 | 2008-10-16 | Glycopegylated Factor 1X | Glycopegylated Factor Ix |
| US20070105755A1 (en) | 2005-10-26 | 2007-05-10 | Neose Technologies, Inc. | One pot desialylation and glycopegylation of therapeutic peptides |
| US20090305967A1 (en) * | 2005-08-19 | 2009-12-10 | Novo Nordisk A/S | Glycopegylated factor vii and factor viia |
| US20090048440A1 (en) * | 2005-11-03 | 2009-02-19 | Neose Technologies, Inc. | Nucleotide Sugar Purification Using Membranes |
| WO2008011633A2 (en) * | 2006-07-21 | 2008-01-24 | Neose Technologies, Inc. | Glycosylation of peptides via o-linked glycosylation sequences |
| EP2054521A4 (en) * | 2006-10-03 | 2012-12-19 | Novo Nordisk As | PROCESS FOR CLEANING POLYPEPTIDE CONJUGATES |
| WO2008060780A2 (en) * | 2006-10-04 | 2008-05-22 | Novo Nordisk A/S | Glycerol linked pegylated sugars and glycopeptides |
| US20080207487A1 (en) * | 2006-11-02 | 2008-08-28 | Neose Technologies, Inc. | Manufacturing process for the production of polypeptides expressed in insect cell-lines |
| PL2144923T3 (pl) * | 2007-04-03 | 2013-12-31 | Biogenerix Ag | Sposoby leczenia z użyciem glikopegilowanego G-CSF |
| US20090053167A1 (en) * | 2007-05-14 | 2009-02-26 | Neose Technologies, Inc. | C-, S- and N-glycosylation of peptides |
| US20110177029A1 (en) * | 2007-06-04 | 2011-07-21 | Novo Nordisk A/S | O-linked glycosylation using n-acetylglucosaminyl transferases |
| CN101778859B (zh) * | 2007-06-12 | 2014-03-26 | 诺和诺德公司 | 改良的用于生产核苷酸糖的方法 |
| US8207112B2 (en) * | 2007-08-29 | 2012-06-26 | Biogenerix Ag | Liquid formulation of G-CSF conjugate |
| EP2242505A4 (en) * | 2008-01-08 | 2012-03-07 | Biogenerix Ag | GLYCOCONJUGATION OF POLYPEPTIDES USING OLIGOSACCHARYLTRANSFERASES |
| CA2715465C (en) | 2008-02-27 | 2017-03-21 | Novo Nordisk A/S | Conjugated factor viii molecules |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4322341A (en) * | 1980-05-13 | 1982-03-30 | Fujisawa Pharmaceutical Co | Peptide, process for preparation thereof and use thereof |
| DK156252C (da) * | 1979-07-31 | 1989-12-18 | Fujisawa Pharmaceutical Co | Analogifremgangsmaade til fremstilling af di-, tri- eller tetrapeptidderivater eller salte deraf |
| EP0027260B1 (en) * | 1979-10-11 | 1985-03-13 | Fujisawa Pharmaceutical Co., Ltd. | Peptides, processes for their preparation and pharmaceutical compositions containing them |
| GR81332B (pm) * | 1980-12-01 | 1984-12-11 | Fujisawa Pharmaceutical Co | |
| US4493794A (en) * | 1980-12-31 | 1985-01-15 | Fujisawa Pharmaceutical Co., Ltd. | Peptide, process for preparation thereof and use thereof |
-
1984
- 1984-03-30 US US06/595,169 patent/US4565653A/en not_active Expired - Fee Related
-
1985
- 1985-03-26 EP EP85302065A patent/EP0157572A3/en not_active Withdrawn
- 1985-03-26 PH PH32046A patent/PH21303A/en unknown
- 1985-03-27 ES ES541620A patent/ES8605821A1/es not_active Expired
- 1985-03-28 EG EG201/85A patent/EG17928A/xx active
- 1985-03-28 GR GR850783A patent/GR850783B/el unknown
- 1985-03-28 DD DD85274551A patent/DD239406A5/de not_active IP Right Cessation
- 1985-03-28 CA CA000477796A patent/CA1270098A/en not_active Expired - Lifetime
- 1985-03-28 PT PT80181A patent/PT80181B/pt not_active IP Right Cessation
- 1985-03-28 ZA ZA852335A patent/ZA852335B/xx unknown
- 1985-03-29 NO NO851278A patent/NO851278L/no unknown
- 1985-03-29 FI FI851271A patent/FI851271L/fi not_active Application Discontinuation
- 1985-03-29 AU AU40523/85A patent/AU552919B2/en not_active Ceased
- 1985-03-29 NZ NZ211634A patent/NZ211634A/xx unknown
- 1985-03-29 KR KR1019850002106A patent/KR870000372B1/ko not_active Expired
- 1985-03-29 JP JP60066380A patent/JPS60224699A/ja active Pending
- 1985-03-29 HU HU851217A patent/HU198086B/hu unknown
- 1985-03-29 DK DK142485A patent/DK142485A/da not_active Application Discontinuation
- 1985-03-29 PL PL25265985A patent/PL252659A1/xx unknown
- 1985-03-29 IL IL74758A patent/IL74758A/xx unknown
-
1986
- 1986-04-22 AU AU56476/86A patent/AU566460B2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| IL74758A0 (en) | 1985-06-30 |
| AU4052385A (en) | 1985-10-03 |
| NZ211634A (en) | 1988-10-28 |
| HUT37443A (en) | 1985-12-28 |
| ZA852335B (en) | 1986-11-26 |
| DK142485D0 (da) | 1985-03-29 |
| HU198086B (en) | 1989-07-28 |
| FI851271A7 (fi) | 1985-10-01 |
| EP0157572A2 (en) | 1985-10-09 |
| PT80181A (en) | 1985-04-01 |
| PL252659A1 (en) | 1985-11-19 |
| AU566460B2 (en) | 1987-10-22 |
| PH21303A (en) | 1987-09-28 |
| IL74758A (en) | 1988-06-30 |
| EP0157572A3 (en) | 1987-01-07 |
| US4565653A (en) | 1986-01-21 |
| KR870000372B1 (ko) | 1987-03-06 |
| ES8605821A1 (es) | 1986-04-01 |
| JPS60224699A (ja) | 1985-11-09 |
| EG17928A (en) | 1991-08-30 |
| FI851271A0 (fi) | 1985-03-29 |
| PT80181B (en) | 1987-03-20 |
| AU5647686A (en) | 1986-09-04 |
| FI851271L (fi) | 1985-10-01 |
| KR850006939A (ko) | 1985-10-25 |
| NO851278L (no) | 1985-10-01 |
| DD239406A5 (de) | 1986-09-24 |
| AU552919B2 (en) | 1986-06-26 |
| CA1270098A (en) | 1990-06-05 |
| ES541620A0 (es) | 1986-04-01 |
| GR850783B (pm) | 1985-11-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PBP | Patent lapsed | ||
| AHB | Application shelved due to non-payment |