DK1415006T3 - Assay til identifikation af inhibitorer af HIV RT-dimerisering - Google Patents

Assay til identifikation af inhibitorer af HIV RT-dimerisering

Info

Publication number
DK1415006T3
DK1415006T3 DK02750730T DK02750730T DK1415006T3 DK 1415006 T3 DK1415006 T3 DK 1415006T3 DK 02750730 T DK02750730 T DK 02750730T DK 02750730 T DK02750730 T DK 02750730T DK 1415006 T3 DK1415006 T3 DK 1415006T3
Authority
DK
Denmark
Prior art keywords
subunits
hiv
complex
measuring
test compound
Prior art date
Application number
DK02750730T
Other languages
Danish (da)
English (en)
Inventor
Nicolas Sluis-Cremer
Michael Parniak
Alex Pelletier
Original Assignee
Boehringer Ingelheim Ca Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Ca Ltd filed Critical Boehringer Ingelheim Ca Ltd
Application granted granted Critical
Publication of DK1415006T3 publication Critical patent/DK1415006T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/48Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90Enzymes; Proenzymes
    • G01N2333/91Transferases (2.)
    • G01N2333/912Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • G01N2333/91205Phosphotransferases in general
    • G01N2333/91245Nucleotidyltransferases (2.7.7)
    • G01N2333/9125Nucleotidyltransferases (2.7.7) with a definite EC number (2.7.7.-)
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00Screening for compounds of potential therapeutic value
    • G01N2500/02Screening involving studying the effect of compounds C on the interaction between interacting molecules A and B (e.g. A = enzyme and B = substrate for A, or A = receptor and B = ligand for the receptor)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
DK02750730T 2001-07-27 2002-07-26 Assay til identifikation af inhibitorer af HIV RT-dimerisering DK1415006T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US30788301P 2001-07-27 2001-07-27
PCT/CA2002/001162 WO2003012127A2 (en) 2001-07-27 2002-07-26 Assay for identifying inhibitors of hiv rt dimerization

Publications (1)

Publication Number Publication Date
DK1415006T3 true DK1415006T3 (da) 2007-09-10

Family

ID=23191565

Family Applications (1)

Application Number Title Priority Date Filing Date
DK02750730T DK1415006T3 (da) 2001-07-27 2002-07-26 Assay til identifikation af inhibitorer af HIV RT-dimerisering

Country Status (10)

Country Link
US (1) US6811970B2 (ja)
EP (1) EP1415006B1 (ja)
JP (1) JP4409287B2 (ja)
AT (1) ATE362550T1 (ja)
AU (1) AU2002355761A1 (ja)
CA (1) CA2450871C (ja)
DE (1) DE60220168T2 (ja)
DK (1) DK1415006T3 (ja)
ES (1) ES2284893T3 (ja)
WO (1) WO2003012127A2 (ja)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120003667A1 (en) * 2007-06-14 2012-01-05 Soumi Gupta Electrophoretic tag-based in vitro assay to quantify dimerization of p66 and p51 sub-units of hiv-1 reverse transcriptase (rt)
JP2016052799A (ja) * 2016-01-21 2016-04-14 大日本印刷株式会社 生体分子印刷物、及びその製造方法
CN109313198B (zh) * 2016-06-09 2022-07-15 雷度米特图尔库公司 用于结合测定的背景阻断剂

Also Published As

Publication number Publication date
US20030087379A1 (en) 2003-05-08
CA2450871A1 (en) 2003-02-13
CA2450871C (en) 2010-09-07
WO2003012127A3 (en) 2003-10-16
ATE362550T1 (de) 2007-06-15
DE60220168T2 (de) 2008-01-17
JP2004535832A (ja) 2004-12-02
AU2002355761A1 (en) 2003-02-17
JP4409287B2 (ja) 2010-02-03
EP1415006B1 (en) 2007-05-16
WO2003012127A2 (en) 2003-02-13
DE60220168D1 (de) 2007-06-28
EP1415006A2 (en) 2004-05-06
US6811970B2 (en) 2004-11-02
ES2284893T3 (es) 2007-11-16

Similar Documents

Publication Publication Date Title
JP3854927B2 (ja) プロテインキナーゼを検出するための方法およびキット
CY1110515T1 (el) Προσδιορισμος αλληλεπιδρασεων ενωσης-πρωτεϊνης με χρηση βιβλιοθηκων μοριων συντηξης πρωτεϊνης-νουκλεϊκου οξεος
DK1474690T3 (da) E2-forskydningsassay til identifikation af inhibitorer af HPV
WO2008051316A3 (en) Nanosensors and related technologies
RU2004126254A (ru) Анализ активности киназы actriib
WO2005073405A3 (en) Catalytic polynucleotide and its use for determination of analytes
GB2433989B (en) Analyte detection system
DK1344059T3 (da) Gennemströmningsassayindretning, diagnostisk kit som omfatter indretningen og anvendelse af assayindretningen til påvisning af en analyt i en pröve
DK1415006T3 (da) Assay til identifikation af inhibitorer af HIV RT-dimerisering
NO20052553L (no) Cobalaminanalyse.
DK608387A (da) Fremgangsmaade og testbaerer til bestemmelse af en analyt
WO2010151656A3 (en) Compositions and methods for identification of parp function, inhibitors, and activators
DK1639122T3 (da) Forbedret testsystem til bestemmelse af nærvær af et antibiotikum i et fluid
CA2737248A1 (en) Colorimetric test for brake fluid
DK1021719T3 (da) Fremgangsmåde til påvisning af antistoffer i en pröve
NO20034707D0 (no) Transcobalamin II testmetode
ATE500505T1 (de) Enzymhemmungsimmunverfahren
DE602005018808D1 (de) Odifizierung der supercoil-topologie von nukleinsäuren sowie modulatoren
WO2001002598A3 (en) Screening for compounds modulating mitochondrial proton leak
CA2797596A1 (en) Ubiquitination assay
WO2021217140A3 (en) Specificity enhancing reagents for covid-19 antibody testing
AR124658A1 (es) Amplificación isotérmica mediada por horquillas (lamp) en un medio en fase sólida
AR124664A1 (es) Amplificación isotérmica mediada por horquillas (lamp) en un medio en fase sólida
Kempton et al. Laboratory Evaluation of Thrombotic Thrombocytopenic Purpura
ATE332978T1 (de) Fluoreszenzverfahren zum messen von enzymaktivität unter verwendung von polyionen