US3922373A
(en)
*
|
1973-03-26 |
1975-11-25 |
Capsulated Systems Inc |
Solid microglobules containing dispersed materials
|
GB1413186A
(en)
*
|
1973-06-27 |
1975-11-12 |
Toyo Jozo Kk |
Process for encapsulation of medicaments
|
JPS5840529B2
(ja)
*
|
1975-09-29 |
1983-09-06 |
明治製菓株式会社 |
ケイコウヨウセイザイノセイホウ
|
DE2812307A1
(de)
*
|
1978-03-21 |
1979-10-04 |
Basf Ag |
Zubereitungen von dispersionsfarbstoffen
|
IT1148784B
(it)
*
|
1980-04-09 |
1986-12-03 |
Eurand Spa |
Procedimento per la preparazione di microcapsule in un veicolo liquido
|
US4507276A
(en)
*
|
1982-08-20 |
1985-03-26 |
Bristol-Myers Company |
Analgesic capsule
|
HU187215B
(en)
*
|
1983-01-26 |
1985-11-28 |
Egyt Gyogyszervegyeszeti Gyar |
Method for producing pharmaceutical product of high actor content and prolonged effect
|
US4670250A
(en)
*
|
1983-10-21 |
1987-06-02 |
Bend Research, Inc. |
Durable controlled release microcapsules
|
US4492720A
(en)
*
|
1983-11-15 |
1985-01-08 |
Benjamin Mosier |
Method of preparing microspheres for intravascular delivery
|
IE58110B1
(en)
*
|
1984-10-30 |
1993-07-14 |
Elan Corp Plc |
Controlled release powder and process for its preparation
|
US5840293A
(en)
*
|
1988-11-16 |
1998-11-24 |
Advanced Polymer Systems, Inc. |
Ionic beads for controlled release and adsorption
|
US5238714A
(en)
*
|
1990-10-02 |
1993-08-24 |
Board Of Regents, The University Of Texas System |
Efficient microcapsule preparation and method of use
|
US5484584A
(en)
*
|
1990-10-02 |
1996-01-16 |
Board Of Regents, The University Of Texas System |
Therapeutic and diagnostic use of modified polymeric microcapsules
|
CH683149A5
(fr)
*
|
1991-07-22 |
1994-01-31 |
Debio Rech Pharma Sa |
Procédé pour la préparation de microsphères en matériau polymère biodégradable.
|
EP0630234B1
(de)
*
|
1992-03-12 |
1997-06-11 |
Alkermes Controlled Therapeutics, Inc. |
Acth enthaltende mikrokugeln mit gesteuerter abgabe
|
US5912015A
(en)
|
1992-03-12 |
1999-06-15 |
Alkermes Controlled Therapeutics, Inc. |
Modulated release from biocompatible polymers
|
US6514533B1
(en)
|
1992-06-11 |
2003-02-04 |
Alkermas Controlled Therapeutics, Inc. |
Device for the sustained release of aggregation-stabilized, biologically active agent
|
FR2693905B1
(fr)
*
|
1992-07-27 |
1994-09-02 |
Rhone Merieux |
Procédé de préparation de microsphères pour la libération prolongée de l'hormone LHRH et ses analogues, microsphères et formulations obtenues.
|
ES2110573T3
(es)
*
|
1992-08-07 |
1998-02-16 |
Takeda Chemical Industries Ltd |
Produccion de microcapsulas de farmacos solubles en agua.
|
US6375872B1
(en)
|
1992-11-17 |
2002-04-23 |
Moore Business Forms |
Microencapsulated adhesive
|
US5278194A
(en)
*
|
1993-03-25 |
1994-01-11 |
Microsome |
Environmentall dispersible syntactic foam
|
JP3645906B2
(ja)
*
|
1993-11-19 |
2005-05-11 |
ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ |
マイクロカプセル封入された3−ピペリジニル−置換1,2−ベンズイソオキサゾール類及び1,2−ベンズイソチアゾール類
|
AU684324B2
(en)
|
1993-11-19 |
1997-12-11 |
Alkermes Controlled Therapeutics Inc. Ii |
Preparation of biodegradable microparticles containing a biologically active agent
|
US5650173A
(en)
*
|
1993-11-19 |
1997-07-22 |
Alkermes Controlled Therapeutics Inc. Ii |
Preparation of biodegradable microparticles containing a biologically active agent
|
US5599583A
(en)
*
|
1994-05-27 |
1997-02-04 |
Micro Flo Company |
Encapsulation with water soluble polymer
|
US6281015B1
(en)
|
1994-12-16 |
2001-08-28 |
Children's Medical Center Corp. |
Localized delivery of factors enhancing survival of transplanted cells
|
US5922253A
(en)
*
|
1995-05-18 |
1999-07-13 |
Alkermes Controlled Therapeutics, Inc. |
Production scale method of forming microparticles
|
JP2000507912A
(ja)
*
|
1995-08-31 |
2000-06-27 |
アルカームズ コントロールド セラピューティックス,インコーポレイテッド |
作用剤の徐放性組成物
|
DE19545257A1
(de)
|
1995-11-24 |
1997-06-19 |
Schering Ag |
Verfahren zur Herstellung von morphologisch einheitlichen Mikrokapseln sowie nach diesem Verfahren hergestellte Mikrokapseln
|
US5792477A
(en)
*
|
1996-05-07 |
1998-08-11 |
Alkermes Controlled Therapeutics, Inc. Ii |
Preparation of extended shelf-life biodegradable, biocompatible microparticles containing a biologically active agent
|
US5945126A
(en)
*
|
1997-02-13 |
1999-08-31 |
Oakwood Laboratories L.L.C. |
Continuous microsphere process
|
US5989463A
(en)
*
|
1997-09-24 |
1999-11-23 |
Alkermes Controlled Therapeutics, Inc. |
Methods for fabricating polymer-based controlled release devices
|
US6824793B1
(en)
|
1998-06-01 |
2004-11-30 |
Chiron Corporation |
Use of hyaluronic acid polymers for mucosal delivery of vaccine antigens and adjuvants
|
US6270802B1
(en)
|
1998-10-28 |
2001-08-07 |
Oakwood Laboratories L.L.C. |
Method and apparatus for formulating microspheres and microcapsules
|
US6194006B1
(en)
*
|
1998-12-30 |
2001-02-27 |
Alkermes Controlled Therapeutics Inc. Ii |
Preparation of microparticles having a selected release profile
|
ATE481108T1
(de)
|
1999-02-26 |
2010-10-15 |
Novartis Vaccines & Diagnostic |
Verwendung von bioadhaesiven und adjuvantien für die mukosale anwendung von antigenen
|
US6204308B1
(en)
|
1999-03-01 |
2001-03-20 |
Novartis Ag |
Organic compounds
|
US6291013B1
(en)
|
1999-05-03 |
2001-09-18 |
Southern Biosystems, Inc. |
Emulsion-based processes for making microparticles
|
AU7136000A
(en)
|
1999-07-19 |
2001-02-05 |
Avantgarb, Llc |
Nanoparticle-based permanent treatments for textiles
|
US6458387B1
(en)
*
|
1999-10-18 |
2002-10-01 |
Epic Therapeutics, Inc. |
Sustained release microspheres
|
US6331317B1
(en)
*
|
1999-11-12 |
2001-12-18 |
Alkermes Controlled Therapeutics Ii Inc. |
Apparatus and method for preparing microparticles
|
US6705757B2
(en)
*
|
1999-11-12 |
2004-03-16 |
Alkermes Controlled Therapeutics, Inc. Ii |
Method and apparatus for preparing microparticles using in-line solvent extraction
|
US6495166B1
(en)
|
1999-11-12 |
2002-12-17 |
Alkermes Controlled Therapeutics Inc. |
Apparatus and method for preparing microparticles using in-line solvent extraction
|
US7838037B2
(en)
|
1999-11-17 |
2010-11-23 |
Tagra Biotechnologies Ltd. |
Method of microencapsulation
|
GB2356386A
(en)
|
1999-11-17 |
2001-05-23 |
Tagra Biotechnologies Ltd |
Microencapsulation
|
DE60119696T2
(de)
|
2000-03-15 |
2007-01-25 |
Wolfgang Ross Sadee |
Naloxon- und naltrexon-analoga in der behandlung bei drogenmissbrauch
|
US6264987B1
(en)
*
|
2000-05-19 |
2001-07-24 |
Alkermes Controlled Therapeutics Inc. Ii |
Method for preparing microparticles having a selected polymer molecular weight
|
US6495164B1
(en)
*
|
2000-05-25 |
2002-12-17 |
Alkermes Controlled Therapeutics, Inc. I |
Preparation of injectable suspensions having improved injectability
|
US6719970B1
(en)
*
|
2000-07-10 |
2004-04-13 |
Alkermes Controlled Therapeutics, Inc. |
Method of generating cartilage
|
US6824822B2
(en)
*
|
2001-08-31 |
2004-11-30 |
Alkermes Controlled Therapeutics Inc. Ii |
Residual solvent extraction method and microparticles produced thereby
|
US6471995B1
(en)
|
2000-09-27 |
2002-10-29 |
Alkermes Controlled Therapeutics, Inc. Ii |
Apparatus and method for preparing microparticles using liquid-liquid extraction
|
US7374782B2
(en)
|
2000-10-27 |
2008-05-20 |
Baxter International Inc. |
Production of microspheres
|
AU2002235253A8
(en)
|
2000-12-21 |
2005-10-06 |
Inhale Therapeutic Syst |
Induced phase transition method for the production of microparticles containing hydrophilic active agents
|
US20020114843A1
(en)
*
|
2000-12-27 |
2002-08-22 |
Ramstack J. Michael |
Preparation of microparticles having improved flowability
|
US6558702B2
(en)
*
|
2001-04-13 |
2003-05-06 |
Alkermes Controlled Therapeutics, Inc. |
Method of modifying the release profile of sustained release compositions
|
US20060269602A1
(en)
*
|
2001-04-13 |
2006-11-30 |
Dasch James R |
Method of modifying the release profile of sustained release compositions
|
US20080026068A1
(en)
*
|
2001-08-16 |
2008-01-31 |
Baxter Healthcare S.A. |
Pulmonary delivery of spherical insulin microparticles
|
WO2003015750A1
(en)
*
|
2001-08-16 |
2003-02-27 |
Baxter International, Inc. |
Propellant-based microparticle formulations
|
EP1471891A4
(de)
*
|
2002-02-08 |
2007-04-11 |
Alkermes Inc |
Zusammensetzungen auf polymerbasis mit verzögerter freisetzung
|
US7041320B1
(en)
|
2002-05-31 |
2006-05-09 |
Biotek, Inc. |
High drug loaded injectable microparticle compositions and methods of treating opioid drug dependence
|
US7157102B1
(en)
|
2002-05-31 |
2007-01-02 |
Biotek, Inc. |
Multi-layered microcapsules and method of preparing same
|
AU2003286472A1
(en)
|
2002-10-17 |
2004-05-04 |
Alkermes Controlled Therapeutics, Inc. Ii |
Microencapsulation and sustained release of biologically active polypeptides
|
US20040191302A1
(en)
|
2003-03-28 |
2004-09-30 |
Davidson Robert S. |
Method and apparatus for minimizing heat, moisture, and shear damage to medicants and other compositions during incorporation of same with edible films
|
US20040131662A1
(en)
|
2003-11-12 |
2004-07-08 |
Davidson Robert S. |
Method and apparatus for minimizing heat, moisture, and shear damage to medicants and other compositions during incorporation of same with edible films
|
US8999372B2
(en)
*
|
2002-11-14 |
2015-04-07 |
Cure Pharmaceutical Corporation |
Methods for modulating dissolution, bioavailability, bioequivalence and drug delivery profile of thin film drug delivery systems, controlled-release thin film dosage formats, and methods for their manufacture and use
|
US9561182B2
(en)
*
|
2003-08-22 |
2017-02-07 |
Cure Pharmaceutical Corporation |
Edible films for administration of medicaments to animals, methods for their manufacture and methods for their use for the treatment of animals
|
US7691296B2
(en)
*
|
2002-11-25 |
2010-04-06 |
Amorepacific Corporation |
Method for stabilizing active components using polyol/polymer microcapsule, and cosmetic composition containing the microcapsule
|
BRPI0409032A
(pt)
*
|
2003-04-10 |
2006-05-02 |
Pr Pharmaceuticals |
método para a produção de micropartìculas à base de emulsão
|
US20070207211A1
(en)
*
|
2003-04-10 |
2007-09-06 |
Pr Pharmaceuticals, Inc. |
Emulsion-based microparticles and methods for the production thereof
|
US7101617B2
(en)
*
|
2003-07-10 |
2006-09-05 |
Motorola, Inc. |
Silicone dispensing with a conformal film
|
US8871269B2
(en)
*
|
2003-07-15 |
2014-10-28 |
Evonik Corporation |
Method for the preparation of controlled release formulations
|
US20050142205A1
(en)
*
|
2003-07-18 |
2005-06-30 |
Julia Rashba-Step |
Methods for encapsulating small spherical particles prepared by controlled phase separation
|
KR101137785B1
(ko)
*
|
2003-07-18 |
2012-04-25 |
백스터 인터내셔널 인코포레이티드 |
제어된 상 분리에 의해 제조된 작은 구형 입자의 제조방법, 이용 방법 및 조성물
|
US20070092452A1
(en)
*
|
2003-07-18 |
2007-04-26 |
Julia Rashba-Step |
Methods for fabrication, uses, compositions of inhalable spherical particles
|
WO2005009375A2
(en)
*
|
2003-07-22 |
2005-02-03 |
Baxter International Inc. |
Small spherical particles of low molecular weight organic molecules and methods of preparation and use thereof
|
CA2533592C
(en)
*
|
2003-07-23 |
2015-11-10 |
Pr Pharmaceuticals, Inc. |
Controlled release compositions
|
EP2409707B8
(de)
*
|
2004-04-15 |
2015-05-06 |
Alkermes Pharma Ireland Limited |
Vorrichtung auf Polymerbasis mit verzögerter Freisetzung
|
US7456254B2
(en)
*
|
2004-04-15 |
2008-11-25 |
Alkermes, Inc. |
Polymer-based sustained release device
|
US20060110423A1
(en)
*
|
2004-04-15 |
2006-05-25 |
Wright Steven G |
Polymer-based sustained release device
|
CA2563957A1
(en)
*
|
2004-04-23 |
2005-11-10 |
Amgen Inc. |
Low molecular weight polylactic acid polymers
|
US20050260272A1
(en)
*
|
2004-05-05 |
2005-11-24 |
Alkermes Controlled Therapeutics, Inc. |
Method of forming microparticles that include a bisphosphonate and a polymer
|
US8728525B2
(en)
*
|
2004-05-12 |
2014-05-20 |
Baxter International Inc. |
Protein microspheres retaining pharmacokinetic and pharmacodynamic properties
|
EP1753404A1
(de)
*
|
2004-05-12 |
2007-02-21 |
Baxter International Inc. |
Mikrokügelchen mit protein; die bei hohen konzentrationen des mittels injizierbar sind
|
DK1765294T3
(da)
*
|
2004-05-12 |
2008-11-10 |
Baxter Int |
Nukleinsyremikrokugler samt deres fremstilling og afgivelse
|
US7884085B2
(en)
*
|
2004-05-12 |
2011-02-08 |
Baxter International Inc. |
Delivery of AS-oligonucleotide microspheres to induce dendritic cell tolerance for the treatment of autoimmune type 1 diabetes
|
US7740861B2
(en)
|
2004-06-16 |
2010-06-22 |
University Of Massachusetts |
Drug delivery product and methods
|
WO2006032039A2
(en)
|
2004-09-17 |
2006-03-23 |
University Of Massachusetts |
Compositions and their uses for lysosomal enzyme deficiencies
|
WO2006078841A1
(en)
*
|
2005-01-21 |
2006-07-27 |
President And Fellows Of Harvard College |
Systems and methods for forming fluidic droplets encapsulated in particles such as colloidal particles
|
US11246913B2
(en)
|
2005-02-03 |
2022-02-15 |
Intarcia Therapeutics, Inc. |
Suspension formulation comprising an insulinotropic peptide
|
MX2007013356A
(es)
*
|
2005-04-27 |
2008-03-26 |
Baxter Int |
Microparticulas modificadas en la superficie y metodos de formacion y uso de las mismas.
|
EP1948245B1
(de)
*
|
2005-10-24 |
2011-10-05 |
University of Massachusetts |
Zusammensetzungen und ihre verwendungen für die gentherapeutische behandlung von knochenerkrankungen
|
US20070281031A1
(en)
*
|
2006-06-01 |
2007-12-06 |
Guohan Yang |
Microparticles and methods for production thereof
|
JP5118139B2
(ja)
*
|
2006-08-04 |
2013-01-16 |
バクスター・インターナショナル・インコーポレイテッド |
新規発症自己免疫性糖尿病を予防および/または逆転させるためのマイクロスフィアに基づく組成物
|
WO2008021133A2
(en)
|
2006-08-09 |
2008-02-21 |
Intarcia Therapeutics, Inc. |
Osmotic delivery systems and piston assemblies
|
WO2008026894A1
(en)
*
|
2006-08-31 |
2008-03-06 |
Sk Chemicals Co., Ltd. |
Method for producing microspheres loaded with drugs and microspheres loaded with drugs produced thereby
|
EP2068845A2
(de)
*
|
2006-10-06 |
2009-06-17 |
Baxter International Inc. |
Mikroverkapselungen mit oberflächenmodifizierten mikropartikeln sowie verfahren zu ihrer herstellung und verwendung
|
CA2680365A1
(en)
*
|
2007-03-22 |
2008-10-02 |
Alkermes, Inc. |
Coacervation process
|
EP2157967B1
(de)
|
2007-04-23 |
2013-01-16 |
Intarcia Therapeutics, Inc |
Suspensionsformulierungen insulinotroper peptide und ihre verwendung
|
US20080317865A1
(en)
*
|
2007-06-20 |
2008-12-25 |
Alkermes, Inc. |
Quench liquids and washing systems for production of microparticles
|
US8748448B2
(en)
|
2007-10-18 |
2014-06-10 |
Aiko Biotechnology |
Combination analgesic employing opioid agonist and neutral antagonist
|
EP2214672B1
(de)
|
2007-10-18 |
2012-10-17 |
Aiko Biotechnology |
Kombinationsanalgetikum mit einem opioid und einem neutralen antagonisten
|
JP2011517279A
(ja)
*
|
2007-10-29 |
2011-06-02 |
ユニバーシティ オブ マサチューセッツ |
核酸(siRNA)送達用の酵母細胞壁粒子(YCWP)多層状ナノ粒子
|
EP2240155B1
(de)
|
2008-02-13 |
2012-06-06 |
Intarcia Therapeutics, Inc |
Vorrichtungen, formulierungen und verfahren zur freisetzung mehrerer wirkstoffe
|
WO2010008582A2
(en)
|
2008-07-18 |
2010-01-21 |
Rxi Pharmaceuticals Corporation |
Phagocytic cell drug delivery system
|
US8323615B2
(en)
*
|
2008-08-20 |
2012-12-04 |
Baxter International Inc. |
Methods of processing multi-phasic dispersions
|
US8367427B2
(en)
*
|
2008-08-20 |
2013-02-05 |
Baxter International Inc. |
Methods of processing compositions containing microparticles
|
US20100047292A1
(en)
*
|
2008-08-20 |
2010-02-25 |
Baxter International Inc. |
Methods of processing microparticles and compositions produced thereby
|
US8323685B2
(en)
*
|
2008-08-20 |
2012-12-04 |
Baxter International Inc. |
Methods of processing compositions containing microparticles
|
EP2949752B1
(de)
|
2008-09-22 |
2017-12-20 |
RXi Pharmaceuticals Corporation |
Selbstfreisetzende rnai-verbindungen von reduzierter grösse
|
WO2010078536A1
(en)
|
2009-01-05 |
2010-07-08 |
Rxi Pharmaceuticals Corporation |
Inhibition of pcsk9 through rnai
|
CN104323981B
(zh)
|
2009-09-28 |
2019-03-12 |
精达制药公司 |
基本稳态药物递送的快速建立和/或终止
|
WO2012008834A1
(en)
|
2010-07-16 |
2012-01-19 |
Delta Crystallon B.V. |
Microparticles comprising a small heat-shock protein
|
WO2012024229A1
(en)
|
2010-08-14 |
2012-02-23 |
University Of Massachusetts |
Yeast cell wall particle for receptor-targeted nanoparticle delivery
|
CA2812063A1
(en)
|
2010-08-30 |
2012-06-07 |
President And Fellows Of Harvard College |
Shear controlled release for stenotic lesions and thrombolytic therapies
|
US20120208755A1
(en)
|
2011-02-16 |
2012-08-16 |
Intarcia Therapeutics, Inc. |
Compositions, Devices and Methods of Use Thereof for the Treatment of Cancers
|
US10350196B2
(en)
|
2013-09-30 |
2019-07-16 |
Zoetis Services Llc |
Long-acting spiro-isoxazoline formulations
|
US9889085B1
(en)
|
2014-09-30 |
2018-02-13 |
Intarcia Therapeutics, Inc. |
Therapeutic methods for the treatment of diabetes and related conditions for patients with high baseline HbA1c
|
WO2016196851A2
(en)
|
2015-06-03 |
2016-12-08 |
Intarcia Therapeutics, Inc. |
Implant placement and removal systems
|
EP3238816B1
(de)
|
2016-04-29 |
2019-10-09 |
Symrise AG |
Verfahren zur herstellung von mikrokapseln
|
MX2018014016A
(es)
|
2016-05-16 |
2019-08-01 |
Intarcia Therapeutics Inc |
Polipéptidos selectivos del receptor de glucagón y métodos para utilizarlos.
|
WO2017199123A1
(en)
|
2016-05-17 |
2017-11-23 |
Ecole Polytechnique Federale De Lausanne (Epfl) |
Device and methods for shell phase removal of core-shell capsules
|
USD840030S1
(en)
|
2016-06-02 |
2019-02-05 |
Intarcia Therapeutics, Inc. |
Implant placement guide
|
USD860451S1
(en)
|
2016-06-02 |
2019-09-17 |
Intarcia Therapeutics, Inc. |
Implant removal tool
|
CN110225762A
(zh)
|
2017-01-03 |
2019-09-10 |
因塔西亚制药公司 |
包括glp-1受体激动剂的连续施用和药物的共同施用的方法
|
CN109651549A
(zh)
*
|
2018-11-21 |
2019-04-19 |
华东理工大学 |
一种用于聚合物多孔材料自修复的微胶囊的制备方法
|
WO2020164705A1
(de)
|
2019-02-13 |
2020-08-20 |
Symrise Ag |
Verfahren zur herstellung von mikrokapseln
|
EP4069412A1
(de)
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2019-12-05 |
2022-10-12 |
Symrise AG |
Verkapselte riechstoffe auf natürlicher aminosäurebasis
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