DK139814B - Analogifremgangsmåde til fremstilling af lokalanæstetisk aktive 2-alkyl-2-(dialkylamino- eller pyrrolidino)-2',6'-acetoxylidider i optisk aktiv eller racemisk form eller farmaceutisk acceptable salte deraf. - Google Patents
Analogifremgangsmåde til fremstilling af lokalanæstetisk aktive 2-alkyl-2-(dialkylamino- eller pyrrolidino)-2',6'-acetoxylidider i optisk aktiv eller racemisk form eller farmaceutisk acceptable salte deraf.Info
- Publication number
- DK139814B DK139814B DK619771AA DK619771A DK139814B DK 139814 B DK139814 B DK 139814B DK 619771A A DK619771A A DK 619771AA DK 619771 A DK619771 A DK 619771A DK 139814 B DK139814 B DK 139814B
- Authority
- DK
- Denmark
- Prior art keywords
- active
- acetoxylidides
- pyrrolidino
- dialkylamino
- alkyl
- Prior art date
Links
- 125000002112 pyrrolidino group Chemical group [*]N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H] 0.000 title 1
- 150000003839 salts Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C53/00—Saturated compounds having only one carboxyl group bound to an acyclic carbon atom or hydrogen
- C07C53/38—Acyl halides
- C07C53/46—Acyl halides containing halogen outside the carbonyl halide group
- C07C53/50—Acyl halides containing halogen outside the carbonyl halide group of acids containing three or more carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10077770A | 1970-12-22 | 1970-12-22 | |
| US00164022A US3812147A (en) | 1970-12-22 | 1971-07-19 | Acylxylidide local anaesthetics |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK139814B true DK139814B (da) | 1979-04-23 |
| DK139814C DK139814C (enrdf_load_html_response) | 1979-10-01 |
Family
ID=26797539
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK619771AA DK139814B (da) | 1970-12-22 | 1971-12-17 | Analogifremgangsmåde til fremstilling af lokalanæstetisk aktive 2-alkyl-2-(dialkylamino- eller pyrrolidino)-2',6'-acetoxylidider i optisk aktiv eller racemisk form eller farmaceutisk acceptable salte deraf. |
Country Status (23)
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4237068A (en) * | 1971-07-28 | 1980-12-02 | Astra Pharmaceutical Products, Inc. | Primary aminoacylanilides |
| US3966934A (en) * | 1971-12-08 | 1976-06-29 | Astra Pharmaceutical Products, Inc. | Synergistic local anesthetic compositions |
| US3957996A (en) * | 1971-12-08 | 1976-05-18 | Astra Pharmaceutical Products, Inc. | Pharmaceutical local anesthetic compositions |
| US3975443A (en) * | 1972-06-06 | 1976-08-17 | Allen & Hanburys Limited | 1-(3,4-dichlorobenzamidomethyl)-cyclohexyldimethylamine |
| JPS598269B2 (ja) * | 1975-08-22 | 1984-02-23 | 萬有製薬株式会社 | オメガ − アミノアルカンサンアリ−ルアミドノ セイホウ |
| JPS57176939A (en) * | 1981-04-03 | 1982-10-30 | Goodrich Co B F | Improved synthesis of hindered amine stabilizer for high polymer materials |
| US4891058A (en) * | 1988-07-18 | 1990-01-02 | Ici Americas Inc. | 1-alkyl-3-aryl imidazolidine-2,4-diones and herbicidal use |
| SE8900685D0 (sv) * | 1989-02-28 | 1989-02-28 | Astra Ab | New compounds |
| US5153226A (en) * | 1989-08-31 | 1992-10-06 | Warner-Lambert Company | Acat inhibitors for treating hypocholesterolemia |
| AU2007322033B2 (en) | 2006-11-20 | 2013-07-11 | President And Fellows Of Harvard College | Methods, compositions, and kits for treating pain and pruritis |
| US20120172429A1 (en) | 2009-07-10 | 2012-07-05 | Woolf Clifford J | Permanently charged sodium and calcium channel blockers as anti- inflammatory agents |
| RU2018107695A (ru) | 2015-08-03 | 2019-09-05 | Президент Энд Феллоуз Оф Гарвард Колледж | Заряженные блокаторы ионных каналов и способы их применения |
| US10828287B2 (en) | 2019-03-11 | 2020-11-10 | Nocion Therapeutics, Inc. | Charged ion channel blockers and methods for use |
| JP7630439B2 (ja) | 2019-03-11 | 2025-02-17 | ノシオン セラピューティクス，インコーポレイテッド | エステル置換イオンチャンネル遮断薬および使用方法 |
| EP3937929A4 (en) | 2019-03-11 | 2022-12-28 | Nocion Therapeutics, Inc. | CHARGED ION CHANNEL BLOCKERS AND METHODS OF USE |
| US10780083B1 (en) | 2019-03-11 | 2020-09-22 | Nocion Therapeutics, Inc. | Charged ion channel blockers and methods for use |
| JP7692834B2 (ja) | 2019-03-11 | 2025-06-16 | ノシオン セラピューティクス，インコーポレイテッド | 荷電したイオンチャンネル遮断薬および使用方法 |
| CA3155568A1 (en) | 2019-11-06 | 2021-05-14 | Bridget Mccarthy Cole | Charged ion channel blockers and methods for use |
| WO2021091585A1 (en) | 2019-11-06 | 2021-05-14 | Nocion Therapeutics, Inc. | Charged ion channel blockers and methods for use |
| IL295950A (en) | 2020-03-11 | 2022-10-01 | Nocion Therapeutics Inc | Charged ion channel blockers and methods of use |
| US12162851B2 (en) | 2020-03-11 | 2024-12-10 | Nocion Therapeutics, Inc. | Charged ion channel blockers and methods for use |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1124837A (en) * | 1966-06-03 | 1968-08-21 | Wyeth John & Brother Ltd | Substituted anilides |
-
1971
- 1971-07-19 US US00164022A patent/US3812147A/en not_active Expired - Lifetime
- 1971-12-07 SE SE7115656A patent/SE393374B/xx unknown
- 1971-12-14 BE BE776656A patent/BE776656A/xx not_active IP Right Cessation
- 1971-12-15 SU SU1726195A patent/SU419023A3/ru active
- 1971-12-16 HU HUAA690A patent/HU163373B/hu unknown
- 1971-12-17 DE DE2162744A patent/DE2162744C3/de not_active Expired
- 1971-12-17 NO NO4669/71A patent/NO135934C/no unknown
- 1971-12-17 DK DK619771AA patent/DK139814B/da not_active IP Right Cessation
- 1971-12-18 IT IT54845/71A patent/IT1066334B/it active
- 1971-12-20 AU AU37099/71A patent/AU468489B2/en not_active Expired
- 1971-12-20 IE IE1609/71A patent/IE35909B1/xx unknown
- 1971-12-20 AT AT1089671A patent/AT319205B/de not_active IP Right Cessation
- 1971-12-21 GB GB5937771A patent/GB1369259A/en not_active Expired
- 1971-12-21 AR AR239721A patent/AR193840A1/es active
- 1971-12-21 CA CA130,662A patent/CA943966A/en not_active Expired
- 1971-12-21 DD DD159785A patent/DD99779A5/xx unknown
- 1971-12-21 PL PL1971152331A patent/PL83097B1/pl unknown
- 1971-12-21 ES ES398210A patent/ES398210A1/es not_active Expired
- 1971-12-21 FR FR7145983A patent/FR2118985B1/fr not_active Expired
- 1971-12-21 BR BR8466/71A patent/BR7108466D0/pt unknown
- 1971-12-22 JP JP10453571A patent/JPS5644063B1/ja active Pending
- 1971-12-22 FI FI3658/71A patent/FI55027C/fi active
- 1971-12-22 NL NLAANVRAGE7117644,A patent/NL172149C/xx not_active IP Right Cessation
-
1974
- 1974-04-24 ES ES425626A patent/ES425626A1/es not_active Expired
-
1982
- 1982-10-26 NL NL8204126A patent/NL8204126A/nl not_active Application Discontinuation
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK139814B (da) | Analogifremgangsmåde til fremstilling af lokalanæstetisk aktive 2-alkyl-2-(dialkylamino- eller pyrrolidino)-2',6'-acetoxylidider i optisk aktiv eller racemisk form eller farmaceutisk acceptable salte deraf. | |
| DK138602B (da) | Analogifremgangsmåde til fremstilling af racemiske eller optisk aktive penicilliner eller salte deraf. | |
| DK138798B (da) | Fremgangsmåde til fremstilling af optisk aktive 1,4-benzodiazepin-2-on-derivater. | |
| NL163216C (nl) | Werkwijze voor de bereiding van farmacologisch werkzame 3-(gesubstitueerde)fenyl-5-hydroxymethyl-1,3- -oxazolidinon-2-on verbindingen; farmaceutisch preparaat met depressiewerende en uricosurische werking. | |
| DK125021B (da) | Analogifremgangsmåde til fremstilling af 1,2,3,4-tetrahydro-4-phenyl-isoquinolinderivater eller syreadditionssalte deraf eller de tilsvarende optisk aktive forbindelser. | |
| DK157246C (da) | Analogifremgangsmaade til fremstilling af n-acylamino-alfa-phenylacetamidocephalosporiner eller farmaceutisk acceptable salte heraf. | |
| DK133899B (da) | Analogifremgangsmåde til fremstilling af benzofuranderivater eller farmaceutisk acceptable syreadditionssalte deraf. | |
| DK142948C (da) | Analogifremgangsmaade til fremstilling af biphenylyl-acetylaminopyridiner eller fysiologisk acceptable salte heraf | |
| DK136060B (da) | Analogifremgangsmåde til fremstilling af 3-substituerede 1,4,5,6-tetrahydropyridiner eller salte deraf. | |
| DK140836B (da) | Analogifremgangsmåde til fremstilling af 1-(4-hydroxy-3-dimethylaminosulfonamidophenyl)-1-hydroxy-2-aminoethanderivater i form af racemater eller optiske antipoder, eller syreadditionssalte deraf. | |
| DK131324B (da) | Fremgangsmåde til fremstilling af et lægemiddel i form af en klar, steril vandig opløsning. | |
| DK128078B (da) | Analogifremgangsmåde til fremstilling af 1,2,3,4-tetrahydroisoquinolinderivater eller salte deraf. | |
| DK126644B (da) | Analogifremgangsmåde til fremstilling af racemiske eller optisk aktive hydroxycrotonsyrer eller salte deraf med uorganiske eller organiske baser. | |
| DK130978B (da) | Analogifremgangsmåde til fremstilling af 2-methylamino-4'-methyl-4-piperazinyl-6-chlor-5-methylthiopyrimidin eller salte deraf. | |
| DK134229B (da) | Analogifremgangsmåde til fremstilling af 1-substituerede 1,4-benzodiazepinderivater eller farmaceutisk anvendelige syreadditionssalte deraf. | |
| DK138988B (da) | Analogifremgangsmåde til fremstilling af racemiske eller optisk aktive morphinanderivater. | |
| DK138797B (da) | Analogifremgangsmåde til fremstilling af 1,4-benzodiazepin-derivater eller N-oxider eller salte deraf. | |
| DK136470B (da) | Analogifremgangsmåde til fremstilling af 2,4-diamino-5-benzylpyrimidinderivater eller salte deraf. | |
| DK138642B (da) | Fremgangsmåde til fremstilling af stereoisomere af 1-(1'-(o-chlorbenzyl)-2'-pyrryl)-2-disek.-butylaminoethanol eller salte deraf. | |
| DK133004C (da) | Analogifremgangsmade til fremstilling af racemiske eller optisk aktive benzomorphanderivater eller salte deraf | |
| DK131374B (da) | Fremgangsmåde til fremstilling af 1,4-benzodiazepinderivater eller salte deraf. | |
| DK139265B (da) | Analogifremgangsmåde til fremstilling af 1,2,4-oxadiazolforbindelser eller farmaceutisk acceptable salte deraf. | |
| DK138425B (da) | Analogifremgangsmåde til fremstilling af 6-aza-3H-1,4-benzodiazepiner eller 6-aza-1,2-dihydro-3H-1,4-benzodiazepiner eller salte heraf. | |
| DK138947B (da) | Analogifremgangsmåde til fremstilling af i 2-stillingen med en pyridylgruppe substituerede imidazolderivater eller pharmaceutisk acceptable salte deraf. | |
| DK137954B (da) | Analogifremgangsmåde til fremstilling af substituerede piperidiner eller optisk aktive antipoder eller salte deraf. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PBP | Patent lapsed |