DK1392321T3 - Fremgangsmåde til behandling af inflammatoriske sygdomme i mave-tarm-kanalen ved anvendelse af topisk aktive corticosteroider - Google Patents

Fremgangsmåde til behandling af inflammatoriske sygdomme i mave-tarm-kanalen ved anvendelse af topisk aktive corticosteroider

Info

Publication number
DK1392321T3
DK1392321T3 DK02723424.4T DK02723424T DK1392321T3 DK 1392321 T3 DK1392321 T3 DK 1392321T3 DK 02723424 T DK02723424 T DK 02723424T DK 1392321 T3 DK1392321 T3 DK 1392321T3
Authority
DK
Denmark
Prior art keywords
gastrointestinal tract
treatment
topically active
inflammatory diseases
active corticosteroids
Prior art date
Application number
DK02723424.4T
Other languages
English (en)
Inventor
B George Mcdonald
Nicholas Stergiopoulos
Original Assignee
Soligenix Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Soligenix Inc filed Critical Soligenix Inc
Application granted granted Critical
Publication of DK1392321T3 publication Critical patent/DK1392321T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • A61K9/2846—Poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK02723424.4T 2001-03-15 2002-03-15 Fremgangsmåde til behandling af inflammatoriske sygdomme i mave-tarm-kanalen ved anvendelse af topisk aktive corticosteroider DK1392321T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US27601301P 2001-03-15 2001-03-15
PCT/US2002/007676 WO2002074316A1 (en) 2001-03-15 2002-03-15 Method of treating inflammatory disorders of the gastrointestinal tract using topical active corticosteroids

Publications (1)

Publication Number Publication Date
DK1392321T3 true DK1392321T3 (da) 2010-11-29

Family

ID=23054783

Family Applications (1)

Application Number Title Priority Date Filing Date
DK02723424.4T DK1392321T3 (da) 2001-03-15 2002-03-15 Fremgangsmåde til behandling af inflammatoriske sygdomme i mave-tarm-kanalen ved anvendelse af topisk aktive corticosteroider

Country Status (11)

Country Link
US (1) US8263582B2 (da)
EP (1) EP1392321B1 (da)
JP (3) JP2005508836A (da)
AT (1) ATE477804T1 (da)
AU (1) AU2002254205B2 (da)
CA (1) CA2441007C (da)
DE (1) DE60237363D1 (da)
DK (1) DK1392321T3 (da)
IL (2) IL157921A0 (da)
NZ (1) NZ528607A (da)
WO (1) WO2002074316A1 (da)

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US20030113366A1 (en) * 2001-12-14 2003-06-19 Macgregor Alexander Reverse-micellar delivery system for controlled transportation and enhanced absorption of agents
US20040086532A1 (en) * 2002-11-05 2004-05-06 Allergan, Inc., Botulinum toxin formulations for oral administration
CL2003002292A1 (es) * 2002-11-08 2005-01-21 Encysive Pharmaceuticals Inc S Composicion farmaceutica que comprende un compuesto derivado de acido carboxilico, uno o mas compuestos terapeuticamente activos y un diluyente farmacologicamente aceptable; y su uso para tratar una enfermedad inflamatoria.
US20050059583A1 (en) * 2003-09-15 2005-03-17 Allergan, Inc. Methods of providing therapeutic effects using cyclosporin components
WO2005053612A2 (en) * 2003-11-26 2005-06-16 Shire Laboratories, Inc. Micellar systems useful for delivery of lipophilic or hydrophobic compounds
KR100638041B1 (ko) * 2003-12-24 2006-10-23 주식회사 삼양사 수용성 약물의 경구투여용 나노입자 조성물 및 그의제조방법
SE0401031D0 (sv) 2004-04-22 2004-04-22 Duocort Ab A new glucocorticoid replacement therapy
US20080102114A1 (en) * 2004-04-23 2008-05-01 Panduranga Rao Koritala Microparticles and Nanoparticles for the Transmucosal Delivery of Therapeutic and Diagnostic Agents
US20060004185A1 (en) * 2004-07-01 2006-01-05 Leese Richard A Peptide antibiotics and peptide intermediates for their prepartion
US7135455B2 (en) * 2004-11-15 2006-11-14 Allergan, Inc Methods for the therapeutic use of cyclosporine components
US7151085B2 (en) 2004-11-15 2006-12-19 Allergan, Inc. Therapeutic methods using cyclosporine components
WO2006072093A2 (en) * 2004-12-30 2006-07-06 Dor Biopharma, Inc. Treatment of graft-versus-host disease and leukemia with beclomethasone dipropionate and prednisone
US8497258B2 (en) 2005-11-12 2013-07-30 The Regents Of The University Of California Viscous budesonide for the treatment of inflammatory diseases of the gastrointestinal tract
US8679545B2 (en) * 2005-11-12 2014-03-25 The Regents Of The University Of California Topical corticosteroids for the treatment of inflammatory diseases of the gastrointestinal tract
US8324192B2 (en) 2005-11-12 2012-12-04 The Regents Of The University Of California Viscous budesonide for the treatment of inflammatory diseases of the gastrointestinal tract
SG10201503411QA (en) 2006-08-03 2015-06-29 Nitec Pharma Ag Delayed-release glucocorticoid treatment of rheumatoid disease
DK2079456T3 (da) 2007-04-04 2013-03-18 Sigmoid Pharma Ltd Farmaceutiske cyclosporinsammensætninger
ES2644496T3 (es) 2007-11-13 2017-11-29 Meritage Pharma, Inc. Composiciones para el tratamiento de la inflamación del tracto gastrointestinal
US20090123551A1 (en) * 2007-11-13 2009-05-14 Meritage Pharma, Inc. Gastrointestinal delivery systems
US9050368B2 (en) * 2007-11-13 2015-06-09 Meritage Pharma, Inc. Corticosteroid compositions
US20100216754A1 (en) * 2007-11-13 2010-08-26 Meritage Pharma, Inc. Compositions for the treatment of inflammation of the gastrointestinal tract
US20090264392A1 (en) * 2008-04-21 2009-10-22 Meritage Pharma, Inc. Treating eosinophilic esophagitis
EP2373160B1 (en) * 2008-12-08 2017-10-25 Soligenix, Inc. Topically active steroids for use in radiation injury
NZ593892A (en) 2008-12-23 2013-11-29 Biosource Pharm Inc Antibiotic compositions for the treatment of gram negative infections
WO2010084188A1 (en) * 2009-01-26 2010-07-29 Nitec Pharma Ag Delayed-release glucocorticoid treatment of asthma
NZ582836A (en) * 2009-01-30 2011-06-30 Nitec Pharma Ag Delayed-release glucocorticoid treatment of rheumatoid arthritis by improving signs and symptoms, showing major or complete clinical response and by preventing from joint damage
US8951989B2 (en) * 2009-04-09 2015-02-10 Actamax Surgical Materials, Llc Hydrogel tissue adhesive having reduced degradation time
WO2010144865A2 (en) * 2009-06-12 2010-12-16 Meritage Pharma, Inc. Methods for treating gastrointestinal disorders
US8415307B1 (en) 2010-06-23 2013-04-09 Biosource Pharm, Inc. Antibiotic compositions for the treatment of gram negative infections
IT1405012B1 (it) * 2010-08-06 2013-12-16 Sofar Spa Composizioni di beclometasone dipropionato in microsfere gastroresistenti a rilascio modificato e processo per il loro ottenimento
GB201020032D0 (en) 2010-11-25 2011-01-12 Sigmoid Pharma Ltd Composition
PT2543357T (pt) * 2011-07-07 2018-04-30 Holy Stone Healthcare Co Ltd Resumo
US10154964B2 (en) * 2011-09-07 2018-12-18 Cosmo Technologies Limited Controlled release and taste masking oral pharmaceutical composition
GB201304662D0 (en) 2013-03-14 2013-05-01 Sigmoid Pharma Ltd Compositions
US20160184474A1 (en) 2013-07-29 2016-06-30 Actamax Surgical Materials, Llc Low swell tissue adhesive and sealant formulations
GB201319791D0 (en) 2013-11-08 2013-12-25 Sigmoid Pharma Ltd Formulations

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DE2260384C3 (de) * 1972-12-09 1979-11-29 Hoechst Ag, 6000 Frankfurt Oral zu applizierendes Corticosteroid-Präparat
SE8903914D0 (sv) * 1989-11-22 1989-11-22 Draco Ab Oral composition for the treatment of inflammatory bowel diseases
US5643602A (en) * 1989-11-22 1997-07-01 Astra Aktiebolag Oral composition for the treatment of inflammatory bowel disease
US5316772A (en) * 1990-12-19 1994-05-31 Solvay & Cie, S.A. (Societe Anonyme) Bilayered oral pharmaceutical composition with pH dependent release
US5286731A (en) * 1991-09-17 1994-02-15 American Home Products Corporation Method of treating immunoinflammatory bowel disease
JPH0840941A (ja) * 1994-07-29 1996-02-13 Kanegafuchi Chem Ind Co Ltd 炎症性腸疾患治療製剤
US6540993B1 (en) * 1995-06-27 2003-04-01 Wyeth Method of treating inflammatory bowel disease using a topical formulation of IL-11
JPH1067657A (ja) * 1996-06-18 1998-03-10 Otsuka Pharmaceut Co Ltd マルチプルユニット型持続性製剤
JPH10231242A (ja) * 1997-02-20 1998-09-02 Taiyo Yakuhin Kogyo Kk 持続性ジクロフェナクナトリウム組成物
DE69819351D1 (de) * 1997-09-11 2003-12-04 Nycomed Danmark As Roskilde Aus mehreren einzeleinheiten zusammengesetzte arzneimittel mit nicht-steroidalen wirkstoffen (nsaids)
IT1301947B1 (it) * 1998-07-28 2000-07-20 Chiesi Farma Spa Formulazioni farmaceutiche di beclometasone dipropionato per iltrattamento di malattie infiammatorie croniche della mucosa
US6632451B2 (en) * 1999-06-04 2003-10-14 Dexcel Pharma Technologies Ltd. Delayed total release two pulse gastrointestinal drug delivery system
HUP0303930A3 (en) * 2001-01-26 2012-09-28 Univ Emory Methods of inducing organ transplant tolerance and correcting hemoglobinopathies

Also Published As

Publication number Publication date
EP1392321A1 (en) 2004-03-03
IL157921A (en) 2011-07-31
EP1392321A4 (en) 2007-10-24
JP2013216700A (ja) 2013-10-24
CA2441007A1 (en) 2002-09-26
ATE477804T1 (de) 2010-09-15
US8263582B2 (en) 2012-09-11
WO2002074316A1 (en) 2002-09-26
JP2005508836A (ja) 2005-04-07
US20030055028A1 (en) 2003-03-20
JP5617015B2 (ja) 2014-10-29
EP1392321B1 (en) 2010-08-18
CA2441007C (en) 2009-06-09
NZ528607A (en) 2007-11-30
DE60237363D1 (de) 2010-09-30
JP2010106038A (ja) 2010-05-13
IL157921A0 (en) 2004-03-28
AU2002254205B2 (en) 2007-05-10

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