DK138995B - Analogifremgangsmåde til fremstilling af 6beta,17-dihydroxy-7alfa-alkoxycarbonyl-3-oxo-17alfa-pregn-4-en-21-carboxylsyre-gamma-lactoner eller de tilsvarende syrer eller disses salte. - Google Patents

Analogifremgangsmåde til fremstilling af 6beta,17-dihydroxy-7alfa-alkoxycarbonyl-3-oxo-17alfa-pregn-4-en-21-carboxylsyre-gamma-lactoner eller de tilsvarende syrer eller disses salte.

Info

Publication number
DK138995B
DK138995B DK425176AA DK425176A DK138995B DK 138995 B DK138995 B DK 138995B DK 425176A A DK425176A A DK 425176AA DK 425176 A DK425176 A DK 425176A DK 138995 B DK138995 B DK 138995B
Authority
DK
Denmark
Prior art keywords
6beta
7alpha
17alpha
pregn
lactones
Prior art date
Application number
DK425176AA
Other languages
Danish (da)
English (en)
Other versions
DK138995C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html
DK425176A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html
Inventor
Aziz Karim
William John Marsheck
Richard Mathias Weier
Original Assignee
Searle & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Searle & Co filed Critical Searle & Co
Publication of DK425176A publication Critical patent/DK425176A/da
Publication of DK138995B publication Critical patent/DK138995B/da
Application granted granted Critical
Publication of DK138995C publication Critical patent/DK138995C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J21/00Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J21/001Lactones
    • C07J21/003Lactones at position 17
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10Antioedematous agents; Diuretics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J1/00Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003Androstane derivatives
    • C07J1/0033Androstane derivatives substituted in position 17 alfa and 17 beta
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/911Microorganisms using fungi

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK425176AA 1975-09-22 1976-09-21 Analogifremgangsmåde til fremstilling af 6beta,17-dihydroxy-7alfa-alkoxycarbonyl-3-oxo-17alfa-pregn-4-en-21-carboxylsyre-gamma-lactoner eller de tilsvarende syrer eller disses salte. DK138995B (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/615,412 US3972871A (en) 1975-09-22 1975-09-22 6β,17-Dihydroxy-7α-(lower alkoxy)carbonyl-3-oxo-17α-pregn-4-ene-21-carboxylic acid γ-lactones and congeners

Publications (3)

Publication Number Publication Date
DK425176A DK425176A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1977-03-23
DK138995B true DK138995B (da) 1978-11-27
DK138995C DK138995C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1979-05-14

Family

ID=24465262

Family Applications (1)

Application Number Title Priority Date Filing Date
DK425176AA DK138995B (da) 1975-09-22 1976-09-21 Analogifremgangsmåde til fremstilling af 6beta,17-dihydroxy-7alfa-alkoxycarbonyl-3-oxo-17alfa-pregn-4-en-21-carboxylsyre-gamma-lactoner eller de tilsvarende syrer eller disses salte.

Country Status (21)

Country Link
US (1) US3972871A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JPS5248657A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AT (1) AT352305B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU (1) AU499083B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
BE (1) BE846437A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA1071620A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CH (1) CH623337A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE2642400A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DK (1) DK138995B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (1) ES451701A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FI (1) FI55670C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FR (1) FR2324309A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GB (1) GB1520948A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GR (1) GR61185B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IE (1) IE44350B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IL (1) IL50524A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NL (1) NL7610477A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NO (1) NO143910C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NZ (1) NZ182127A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PT (1) PT65616B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
SE (1) SE418295B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3972871A (en) * 1975-09-22 1976-08-03 G. D. Searle & Co. 6β,17-Dihydroxy-7α-(lower alkoxy)carbonyl-3-oxo-17α-pregn-4-ene-21-carboxylic acid γ-lactones and congeners
US4069219A (en) * 1976-12-27 1978-01-17 G. D. Searle & Co. 7ξ-(Alkoxycarbonyl)-6ξ-alkyl/halo-17-hydroxy-3-oxo-17α-pregn-4-ene-21-carboxylic acid γ-lactones and corresponding 21-carboxylic acids, their salts, and esters
JPS6063577U (ja) * 1983-10-07 1985-05-04 東レ株式会社 糸条のインタ−レ−ス装置
EP0973791B1 (en) * 1995-12-11 2007-06-20 G.D. Searle LLC. Process for the preparation of an epoxy compound
US6887991B1 (en) * 1996-12-11 2005-05-03 G. D. Searle & Company Processes for preparation of 9, 11-epoxy steroids and intermediates useful therein

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2237143A1 (de) * 1972-07-28 1974-02-14 Hoechst Ag Verfahren zur herstellung von beta(3-keto-7alpha-acetylthio-17beta-hydroxy4-androsten-17alpha-yl)-propionsaeuregamma-lacton und dessen 1-dehydro-derivat
GB1368006A (en) * 1972-08-24 1974-09-25 Searle & Co 4alpha,7alpha-carbonyl-5-cyano-17-hzydroxy-3-oxo-5beta,17alpha- pregnane-21-carboxylic acid ypsilon-lactone
US3972871A (en) * 1975-09-22 1976-08-03 G. D. Searle & Co. 6β,17-Dihydroxy-7α-(lower alkoxy)carbonyl-3-oxo-17α-pregn-4-ene-21-carboxylic acid γ-lactones and congeners

Also Published As

Publication number Publication date
PT65616A (en) 1976-10-01
JPS5248657A (en) 1977-04-18
FI55670C (fi) 1979-09-10
CH623337A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1981-05-29
ES451701A1 (es) 1978-01-01
FI762690A7 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1977-03-23
AT352305B (de) 1979-09-10
BE846437A (fr) 1977-03-22
FI55670B (fi) 1979-05-31
DK138995C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1979-05-14
NL7610477A (nl) 1977-03-24
NO143910C (no) 1981-06-03
GB1520948A (en) 1978-08-09
PT65616B (en) 1978-04-05
SE418295B (sv) 1981-05-18
SE7610449L (sv) 1977-03-23
DK425176A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1977-03-23
FR2324309B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1979-03-02
IL50524A (en) 1979-12-30
IL50524A0 (en) 1976-11-30
US3972871A (en) 1976-08-03
DE2642400A1 (de) 1977-03-24
ATA698476A (de) 1979-02-15
NZ182127A (en) 1978-11-13
NO143910B (no) 1981-01-26
CA1071620A (en) 1980-02-12
AU499083B2 (en) 1979-04-05
IE44350B1 (en) 1981-11-04
GR61185B (en) 1978-10-05
IE44350L (en) 1977-03-22
NO763231L (no) 1977-03-23
FR2324309A1 (fr) 1977-04-15
AU1796276A (en) 1978-04-06

Similar Documents

Publication Publication Date Title
DK136714B (da) Analogifremgangsmåde til fremstilling af substituerede piperidinderivater eller syreadditionssalte deraf.
DK144010C (da) Analogifremgangsmaade til fremstilling af 2-piperazinyl-6,7-dimethoxyquinazoliner eller syreadditionssalte deraf
DK140430B (da) Analogifremgangsmåde til fremstilling af 3-aryloxy-3-phenylpropylaminer eller syreadditionssalte heraf.
DK141048B (da) Analogifremgangsmåde til fremstilling af et ethanolaminderivat eller et syreadditionssalte deraf.
DK131725B (da) Analogifremgangsmåde til fremstilling af 2,4-diaminoquinazoliner eller salte deraf.
DK140461B (da) Analogifremgangsmåde til fremstilling af 8-azapurin-6-oner eller salte deraf.
DK136157B (da) Analogifremgangsmåde til fremstilling af 3alfa-hydroxy-17beta-karboxylsyrederivater af androstanrækken eller salte deraf.
DK138893B (da) Analogifremgangsmåde til fremstilling af 1-(indolyl-3-alkyl)-4-ureido-piperidiner eller -thioureido-piperidiner eller syreadditionssalte deraf.
DK138321B (da) Analogifremgangsmåde til fremstilling af 5-halogen-2,3-kresotinsyrederivater.
DK131788B (da) Fremgangsmåde til fremstilling af beta-(3-keto-7alfa-thioacyl-17beta-hydroxy-4-androsten-17alfa-yl)-propionsyre-gamma-lactoner.
DK140590B (da) Analogifremgangsmåde til fremstilling af 4-cyclopropylmethylenoxy-3-chlorphenyleddikesyre eller salte heraf.
DK138995B (da) Analogifremgangsmåde til fremstilling af 6beta,17-dihydroxy-7alfa-alkoxycarbonyl-3-oxo-17alfa-pregn-4-en-21-carboxylsyre-gamma-lactoner eller de tilsvarende syrer eller disses salte.
DK138943B (da) Analogifremgangsmåde til fremstilling af substituerede dibenzocyclohepten-carboxamider eller syreadditionssalte deraf.
DK136470B (da) Analogifremgangsmåde til fremstilling af 2,4-diamino-5-benzylpyrimidinderivater eller salte deraf.
DK140431B (da) Analogifremgangsmåde til fremstilling af et N2-dansyl-L-arginin-derivat eller syreadditionssalte deraf.
DK138265B (da) Analogifremgangsmåde til fremstilling af 4,4-diaryl-2-hydroxybutylaminer eller syreadditionssalte eller kvaternære ammoniumsalte deraf.
DK138117B (da) Analogifremgangsmåde til fremstilling af isoindolinderivater eller syreadditionssalte deraf.
DK138544B (da) Analogifremgangsmåde til fremstilling af 2beta,6beta,16beta-triamino-3alfa,5alfa,17beta-trihydroxyandrostan-derivater eller syreadditionssalte eller di- eller trikvaternære salte deraf.
DK140848B (da) Analogifremgangsmåde til fremstilling af 17a-hydroxy-6,7-methylen-3-oxo-D-homo-17aalfa-pregna-4,16-dien-21-carboxylsyrer eller de tilsvarende lactoner eller salte deraf.
DK134014B (da) Analogifremgangsmåde til fremstilling af cycloalkyllactamimider eller syreadditionssalte deraf.
DK135504B (da) Analogifremgangsmåde til fremstilling af 6-substituerede 3-carbethoxyhydrazinopyridaziner eller salte deraf.
DK138449B (da) Fremgangsmåde til fremstilling af D(-)-penicillamin eller salte deraf.
DK131634B (da) Fremgangsmåde til fremstilling af beta-(3-keto-7alfa-acetylthio-17beta-hydroxy-4-androsten-17alfa-yl)-propionsyre-gamma-lacton.
DK140458B (da) Analogifremgangsmåde til fremstilling af antidepressivt virkende aminoethyloximethere eller salte heraf.
DK138266B (da) Analogifremgangsmåde til fremstilling af basiske derivater af 1-aryl-2-oxo-2,4,5,6,7,7a-hexahydroindoler eller syreadditionssalte deraf.