FI55670C - Foerfarande foer framstaellning av diuretiskt verkande 6beta 17beta-dihydroxi-7alfa-(laegrealkoxi)-karbonyl-3-oxo-17alfa-pregn-4-en-21-karboxylsyra-ny-laktoner - Google Patents

Foerfarande foer framstaellning av diuretiskt verkande 6beta 17beta-dihydroxi-7alfa-(laegrealkoxi)-karbonyl-3-oxo-17alfa-pregn-4-en-21-karboxylsyra-ny-laktoner

Info

Publication number
FI55670C
FI55670C FI762690A FI762690A FI55670C FI 55670 C FI55670 C FI 55670C FI 762690 A FI762690 A FI 762690A FI 762690 A FI762690 A FI 762690A FI 55670 C FI55670 C FI 55670C
Authority
FI
Finland
Prior art keywords
laegrealcoxy
diuretical
carboxylsyra
7alfa
17alfa
Prior art date
Application number
FI762690A
Other languages
English (en)
Other versions
FI762690A (fi
FI55670B (fi
Inventor
Aziz Karim
William John Marsheck
Richard Mathias Weier
Original Assignee
Searle & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Searle & Co filed Critical Searle & Co
Publication of FI762690A publication Critical patent/FI762690A/fi
Application granted granted Critical
Publication of FI55670B publication Critical patent/FI55670B/fi
Publication of FI55670C publication Critical patent/FI55670C/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J21/00Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J21/001Lactones
    • C07J21/003Lactones at position 17
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10Antioedematous agents; Diuretics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J1/00Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003Androstane derivatives
    • C07J1/0033Androstane derivatives substituted in position 17 alfa and 17 beta
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/911Microorganisms using fungi

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
FI762690A 1975-09-22 1976-09-21 Foerfarande foer framstaellning av diuretiskt verkande 6beta 17beta-dihydroxi-7alfa-(laegrealkoxi)-karbonyl-3-oxo-17alfa-pregn-4-en-21-karboxylsyra-ny-laktoner FI55670C (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/615,412 US3972871A (en) 1975-09-22 1975-09-22 6β,17-Dihydroxy-7α-(lower alkoxy)carbonyl-3-oxo-17α-pregn-4-ene-21-carboxylic acid γ-lactones and congeners

Publications (3)

Publication Number Publication Date
FI762690A FI762690A (fi) 1977-03-23
FI55670B FI55670B (fi) 1979-05-31
FI55670C true FI55670C (fi) 1979-09-10

Family

ID=24465262

Family Applications (1)

Application Number Title Priority Date Filing Date
FI762690A FI55670C (fi) 1975-09-22 1976-09-21 Foerfarande foer framstaellning av diuretiskt verkande 6beta 17beta-dihydroxi-7alfa-(laegrealkoxi)-karbonyl-3-oxo-17alfa-pregn-4-en-21-karboxylsyra-ny-laktoner

Country Status (21)

Country Link
US (1) US3972871A (fi)
JP (1) JPS5248657A (fi)
AT (1) AT352305B (fi)
AU (1) AU499083B2 (fi)
BE (1) BE846437A (fi)
CA (1) CA1071620A (fi)
CH (1) CH623337A5 (fi)
DE (1) DE2642400A1 (fi)
DK (1) DK138995B (fi)
ES (1) ES451701A1 (fi)
FI (1) FI55670C (fi)
FR (1) FR2324309A1 (fi)
GB (1) GB1520948A (fi)
GR (1) GR61185B (fi)
IE (1) IE44350B1 (fi)
IL (1) IL50524A (fi)
NL (1) NL7610477A (fi)
NO (1) NO143910C (fi)
NZ (1) NZ182127A (fi)
PT (1) PT65616B (fi)
SE (1) SE418295B (fi)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3972871A (en) * 1975-09-22 1976-08-03 G. D. Searle & Co. 6β,17-Dihydroxy-7α-(lower alkoxy)carbonyl-3-oxo-17α-pregn-4-ene-21-carboxylic acid γ-lactones and congeners
US4069219A (en) * 1976-12-27 1978-01-17 G. D. Searle & Co. 7ξ-(Alkoxycarbonyl)-6ξ-alkyl/halo-17-hydroxy-3-oxo-17α-pregn-4-ene-21-carboxylic acid γ-lactones and corresponding 21-carboxylic acids, their salts, and esters
JPS6063577U (ja) * 1983-10-07 1985-05-04 東レ株式会社 糸条のインタ−レ−ス装置
CN100384866C (zh) * 1995-12-11 2008-04-30 G·D·瑟尔公司 制备7α-羧基9,11-环氧甾族化合物的方法和其中使用的中间体以及烯双键环氧化作用的一般方法
US6887991B1 (en) * 1996-12-11 2005-05-03 G. D. Searle & Company Processes for preparation of 9, 11-epoxy steroids and intermediates useful therein

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2237143A1 (de) * 1972-07-28 1974-02-14 Hoechst Ag Verfahren zur herstellung von beta(3-keto-7alpha-acetylthio-17beta-hydroxy4-androsten-17alpha-yl)-propionsaeuregamma-lacton und dessen 1-dehydro-derivat
GB1368006A (en) * 1972-08-24 1974-09-25 Searle & Co 4alpha,7alpha-carbonyl-5-cyano-17-hzydroxy-3-oxo-5beta,17alpha- pregnane-21-carboxylic acid ypsilon-lactone
US3972871A (en) * 1975-09-22 1976-08-03 G. D. Searle & Co. 6β,17-Dihydroxy-7α-(lower alkoxy)carbonyl-3-oxo-17α-pregn-4-ene-21-carboxylic acid γ-lactones and congeners

Also Published As

Publication number Publication date
GR61185B (en) 1978-10-05
GB1520948A (en) 1978-08-09
IE44350L (en) 1977-03-22
AT352305B (de) 1979-09-10
US3972871A (en) 1976-08-03
NL7610477A (nl) 1977-03-24
DK425176A (fi) 1977-03-23
DK138995B (da) 1978-11-27
ES451701A1 (es) 1978-01-01
DE2642400A1 (de) 1977-03-24
NO763231L (no) 1977-03-23
AU499083B2 (en) 1979-04-05
NO143910C (no) 1981-06-03
CA1071620A (en) 1980-02-12
FR2324309A1 (fr) 1977-04-15
BE846437A (fr) 1977-03-22
SE7610449L (sv) 1977-03-23
SE418295B (sv) 1981-05-18
FR2324309B1 (fi) 1979-03-02
IL50524A (en) 1979-12-30
FI762690A (fi) 1977-03-23
PT65616A (en) 1976-10-01
NZ182127A (en) 1978-11-13
CH623337A5 (fi) 1981-05-29
PT65616B (en) 1978-04-05
FI55670B (fi) 1979-05-31
DK138995C (fi) 1979-05-14
JPS5248657A (en) 1977-04-18
ATA698476A (de) 1979-02-15
IL50524A0 (en) 1976-11-30
NO143910B (no) 1981-01-26
AU1796276A (en) 1978-04-06
IE44350B1 (en) 1981-11-04

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Legal Events

Date Code Title Description
MM Patent lapsed

Owner name: G D SEARLE & CO.