FI55851B - Foerfarande foer framstaellning av antiandrogeniskt verksamma 16-dehydro-androstanderivat - Google Patents

Foerfarande foer framstaellning av antiandrogeniskt verksamma 16-dehydro-androstanderivat

Info

Publication number
FI55851B
FI55851B FI762058A FI762058A FI55851B FI 55851 B FI55851 B FI 55851B FI 762058 A FI762058 A FI 762058A FI 762058 A FI762058 A FI 762058A FI 55851 B FI55851 B FI 55851B
Authority
FI
Finland
Prior art keywords
antifreamening
androstanderivat
verksamma
dehydro
frequency refrigeration
Prior art date
Application number
FI762058A
Other languages
English (en)
Other versions
FI762058A (fi
FI55851C (fi
Inventor
Arthur Friedrich Marx
Nicolaas Cornelis Mar Barendse
Original Assignee
Gist Brocades Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gist Brocades Nv filed Critical Gist Brocades Nv
Publication of FI762058A publication Critical patent/FI762058A/fi
Publication of FI55851B publication Critical patent/FI55851B/fi
Application granted granted Critical
Publication of FI55851C publication Critical patent/FI55851C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003—Androstane derivatives
    • C07J1/0011—Androstane derivatives substituted in position 17 by a keto group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J13/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17
    • C07J13/005—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17 with double bond in position 16 (17)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
    • C07J53/002—Carbocyclic rings fused
    • C07J53/004—3 membered carbocyclic rings
    • C07J53/005—3 membered carbocyclic rings in position 12
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
    • C07J53/002—Carbocyclic rings fused
    • C07J53/004—3 membered carbocyclic rings
    • C07J53/007—3 membered carbocyclic rings in position 6-7
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/001—Oxiranes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Dermatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FI762058A 1975-07-16 1976-07-15 Foerfarande foer framstaellning av antiandrogeniskt verksamma 16-dehydro-androstanderivat FI55851C (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB29898/75A GB1550343A (en) 1975-07-16 1975-07-16 Androstane derivatives

Publications (3)

Publication Number Publication Date
FI762058A FI762058A (fi) 1977-01-17
FI55851B true FI55851B (fi) 1979-06-29
FI55851C FI55851C (fi) 1979-10-10

Family

ID=10298992

Family Applications (1)

Application Number Title Priority Date Filing Date
FI762058A FI55851C (fi) 1975-07-16 1976-07-15 Foerfarande foer framstaellning av antiandrogeniskt verksamma 16-dehydro-androstanderivat

Country Status (20)

Country Link
US (1) US4075233A (fi)
JP (1) JPS5212159A (fi)
AT (1) AT362085B (fi)
AU (1) AU506101B2 (fi)
BE (1) BE844169A (fi)
CH (1) CH626379A5 (fi)
DE (1) DE2631915A1 (fi)
DK (1) DK142877B (fi)
FI (1) FI55851C (fi)
FR (1) FR2317934A1 (fi)
GB (1) GB1550343A (fi)
HU (1) HU175369B (fi)
IE (1) IE43693B1 (fi)
IT (1) IT1063150B (fi)
LU (1) LU75394A1 (fi)
NL (1) NL7607824A (fi)
NO (1) NO146865C (fi)
NZ (1) NZ181482A (fi)
SE (1) SE7608092L (fi)
ZA (1) ZA764195B (fi)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1566905A (en) * 1977-03-28 1980-05-08 Gist Brocades Nv Steroids of the a-nor-androstane and a-nor-estrane series
DE3115995A1 (de) * 1981-04-13 1982-11-04 Schering Ag, 1000 Berlin Und 4619 Bergkamen D-homo-4,17-androstadien-3-on, verfahren zu seiner herstellung und diese verbindung enthaltende pharmazeutische praeparate
JPS58185406A (ja) * 1982-04-20 1983-10-29 Mitsubishi Gas Chem Co Inc 過硼酸塩の製造方法
JPS6069096A (ja) * 1983-08-02 1985-04-19 リサ−チ・コ−ポレイシヨン 新規ステロイド
DE3514272A1 (de) * 1985-04-17 1986-10-23 Schering AG, 1000 Berlin und 4709 Bergkamen Dermatica
US4898694A (en) * 1987-11-25 1990-02-06 Schwartz Arthur G 17-Hydroxy-steroids
US5001119A (en) * 1987-11-25 1991-03-19 Schwartz Arthur G 16-substituted androstanes and 16-substituted androstenes
US5028631A (en) * 1987-11-25 1991-07-02 Schwartz Arthur G Homoandrostan-17-one and homoandrosten-17-ones
US5175154A (en) * 1987-11-25 1992-12-29 Research Corporation Technologies, Inc. 5 α-pregnan-20-ones and 5-pregnen-20-ones and related compounds
US5925774A (en) 1991-01-07 1999-07-20 Pherin Corporation Estrenes for inducing hypothalamic effects
US5883087A (en) * 1991-01-07 1999-03-16 Pherin Corporation Androstane steroids as neurochemical initiators of change in human hypothalamic function and related pharmaceutical compositions and methods
US5969168A (en) * 1991-01-07 1999-10-19 Pherin Corporation Androstanes for inducing hypothalamic effects
EP1340502A3 (en) * 1993-06-15 2004-01-21 Pherin Corporation Androstane steroids as neurochemical initiators of change in human hypothalamic function and related pharmaceutical compositions and methods
US6331534B1 (en) 1994-08-04 2001-12-18 Pherin Pharmaceuticals, Inc. Steroids as neurochemical stimulators of the VNO to alleviate pain
US6057439A (en) * 1994-08-04 2000-05-02 Pherin Corporation Steroids as neurochemical stimulators of the VNO to alleviate symptoms of PMS and anxiety
US6117860A (en) * 1994-08-04 2000-09-12 Pherin Pharmaceuticals, Inc. Steroids as neurochemical stimulators of the VNO to treat paroxistic tachycardia
US6066627A (en) * 1994-08-04 2000-05-23 Pherin Corporation Steroids as neurochemical initiators of change in human blood levels of LH
CN112778390B (zh) * 2021-01-22 2022-09-30 厦门欧瑞捷生物科技有限公司 一种雄烯酮的合成方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3501462A (en) * 1966-05-02 1970-03-17 Sterling Drug Inc 17-cyclopropyl steroids

Also Published As

Publication number Publication date
IE43693B1 (en) 1981-05-06
DK142877B (da) 1981-02-16
CH626379A5 (fi) 1981-11-13
DK321676A (fi) 1977-01-17
BE844169A (fr) 1977-01-17
DK142877C (fi) 1981-09-28
FI762058A (fi) 1977-01-17
FI55851C (fi) 1979-10-10
JPS5212159A (en) 1977-01-29
FR2317934B1 (fi) 1980-11-07
AT362085B (de) 1981-04-27
AU1593876A (en) 1978-01-19
HU175369B (hu) 1980-07-28
SE7608092L (sv) 1977-01-17
NL7607824A (nl) 1977-01-18
ATA519776A (de) 1980-09-15
US4075233A (en) 1978-02-21
IE43693L (en) 1977-01-16
DE2631915A1 (de) 1977-02-03
NO762483L (fi) 1977-01-18
IT1063150B (it) 1985-02-11
ZA764195B (en) 1977-07-27
NO146865C (no) 1982-12-22
AU506101B2 (en) 1979-12-13
NZ181482A (en) 1978-12-18
NO146865B (no) 1982-09-13
LU75394A1 (fi) 1977-02-28
FR2317934A1 (fr) 1977-02-11
GB1550343A (en) 1979-08-15

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Legal Events

Date Code Title Description
MM Patent lapsed

Owner name: GIST-BROCADES N.V.