DK138995B - Analogifremgangsmåde til fremstilling af 6beta,17-dihydroxy-7alfa-alkoxycarbonyl-3-oxo-17alfa-pregn-4-en-21-carboxylsyre-gamma-lactoner eller de tilsvarende syrer eller disses salte. - Google Patents

Analogifremgangsmåde til fremstilling af 6beta,17-dihydroxy-7alfa-alkoxycarbonyl-3-oxo-17alfa-pregn-4-en-21-carboxylsyre-gamma-lactoner eller de tilsvarende syrer eller disses salte.

Info

Publication number
DK138995B
DK138995B DK425176AA DK425176A DK138995B DK 138995 B DK138995 B DK 138995B DK 425176A A DK425176A A DK 425176AA DK 425176 A DK425176 A DK 425176A DK 138995 B DK138995 B DK 138995B
Authority
DK
Denmark
Prior art keywords
6beta
7alpha
17alpha
pregn
lactones
Prior art date
Application number
DK425176AA
Other languages
English (en)
Other versions
DK425176A (da
DK138995C (da
Inventor
Aziz Karim
William John Marsheck
Richard Mathias Weier
Original Assignee
Searle & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Searle & Co filed Critical Searle & Co
Publication of DK425176A publication Critical patent/DK425176A/da
Publication of DK138995B publication Critical patent/DK138995B/da
Application granted granted Critical
Publication of DK138995C publication Critical patent/DK138995C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J21/00Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J21/001Lactones
    • C07J21/003Lactones at position 17
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10Antioedematous agents; Diuretics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J1/00Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003Androstane derivatives
    • C07J1/0033Androstane derivatives substituted in position 17 alfa and 17 beta
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/911Microorganisms using fungi

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK425176AA 1975-09-22 1976-09-21 Analogifremgangsmåde til fremstilling af 6beta,17-dihydroxy-7alfa-alkoxycarbonyl-3-oxo-17alfa-pregn-4-en-21-carboxylsyre-gamma-lactoner eller de tilsvarende syrer eller disses salte. DK138995B (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/615,412 US3972871A (en) 1975-09-22 1975-09-22 6β,17-Dihydroxy-7α-(lower alkoxy)carbonyl-3-oxo-17α-pregn-4-ene-21-carboxylic acid γ-lactones and congeners

Publications (3)

Publication Number Publication Date
DK425176A DK425176A (da) 1977-03-23
DK138995B true DK138995B (da) 1978-11-27
DK138995C DK138995C (da) 1979-05-14

Family

ID=24465262

Family Applications (1)

Application Number Title Priority Date Filing Date
DK425176AA DK138995B (da) 1975-09-22 1976-09-21 Analogifremgangsmåde til fremstilling af 6beta,17-dihydroxy-7alfa-alkoxycarbonyl-3-oxo-17alfa-pregn-4-en-21-carboxylsyre-gamma-lactoner eller de tilsvarende syrer eller disses salte.

Country Status (21)

Country Link
US (1) US3972871A (da)
JP (1) JPS5248657A (da)
AT (1) AT352305B (da)
AU (1) AU499083B2 (da)
BE (1) BE846437A (da)
CA (1) CA1071620A (da)
CH (1) CH623337A5 (da)
DE (1) DE2642400A1 (da)
DK (1) DK138995B (da)
ES (1) ES451701A1 (da)
FI (1) FI55670C (da)
FR (1) FR2324309A1 (da)
GB (1) GB1520948A (da)
GR (1) GR61185B (da)
IE (1) IE44350B1 (da)
IL (1) IL50524A (da)
NL (1) NL7610477A (da)
NO (1) NO143910C (da)
NZ (1) NZ182127A (da)
PT (1) PT65616B (da)
SE (1) SE418295B (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3972871A (en) * 1975-09-22 1976-08-03 G. D. Searle & Co. 6β,17-Dihydroxy-7α-(lower alkoxy)carbonyl-3-oxo-17α-pregn-4-ene-21-carboxylic acid γ-lactones and congeners
US4069219A (en) * 1976-12-27 1978-01-17 G. D. Searle & Co. 7ξ-(Alkoxycarbonyl)-6ξ-alkyl/halo-17-hydroxy-3-oxo-17α-pregn-4-ene-21-carboxylic acid γ-lactones and corresponding 21-carboxylic acids, their salts, and esters
JPS6063577U (ja) * 1983-10-07 1985-05-04 東レ株式会社 糸条のインタ−レ−ス装置
PT973791E (pt) * 1995-12-11 2007-09-26 Searle Llc Processo para a preparação de um composto epoxi
US6887991B1 (en) * 1996-12-11 2005-05-03 G. D. Searle & Company Processes for preparation of 9, 11-epoxy steroids and intermediates useful therein

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2237143A1 (de) * 1972-07-28 1974-02-14 Hoechst Ag Verfahren zur herstellung von beta(3-keto-7alpha-acetylthio-17beta-hydroxy4-androsten-17alpha-yl)-propionsaeuregamma-lacton und dessen 1-dehydro-derivat
GB1368006A (en) * 1972-08-24 1974-09-25 Searle & Co 4alpha,7alpha-carbonyl-5-cyano-17-hzydroxy-3-oxo-5beta,17alpha- pregnane-21-carboxylic acid ypsilon-lactone
US3972871A (en) * 1975-09-22 1976-08-03 G. D. Searle & Co. 6β,17-Dihydroxy-7α-(lower alkoxy)carbonyl-3-oxo-17α-pregn-4-ene-21-carboxylic acid γ-lactones and congeners

Also Published As

Publication number Publication date
ATA698476A (de) 1979-02-15
NO763231L (no) 1977-03-23
FR2324309A1 (fr) 1977-04-15
GR61185B (en) 1978-10-05
SE418295B (sv) 1981-05-18
FI55670C (fi) 1979-09-10
NL7610477A (nl) 1977-03-24
SE7610449L (sv) 1977-03-23
AT352305B (de) 1979-09-10
CH623337A5 (da) 1981-05-29
FI55670B (fi) 1979-05-31
IE44350B1 (en) 1981-11-04
PT65616B (en) 1978-04-05
IE44350L (en) 1977-03-22
AU1796276A (en) 1978-04-06
DK425176A (da) 1977-03-23
NO143910B (no) 1981-01-26
JPS5248657A (en) 1977-04-18
DK138995C (da) 1979-05-14
BE846437A (fr) 1977-03-22
PT65616A (en) 1976-10-01
NO143910C (no) 1981-06-03
DE2642400A1 (de) 1977-03-24
US3972871A (en) 1976-08-03
ES451701A1 (es) 1978-01-01
GB1520948A (en) 1978-08-09
FR2324309B1 (da) 1979-03-02
AU499083B2 (en) 1979-04-05
IL50524A0 (en) 1976-11-30
FI762690A (da) 1977-03-23
IL50524A (en) 1979-12-30
CA1071620A (en) 1980-02-12
NZ182127A (en) 1978-11-13

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