IE44350B1 - 6 ,17-dihydroxy-7a-(lower alkoxy)carbonyl-3-oxo-17a-pregn-4-ene-21-carboxylic acid -lactones and congeners - Google Patents

6 ,17-dihydroxy-7a-(lower alkoxy)carbonyl-3-oxo-17a-pregn-4-ene-21-carboxylic acid -lactones and congeners

Info

Publication number
IE44350B1
IE44350B1 IE2083/76A IE208376A IE44350B1 IE 44350 B1 IE44350 B1 IE 44350B1 IE 2083/76 A IE2083/76 A IE 2083/76A IE 208376 A IE208376 A IE 208376A IE 44350 B1 IE44350 B1 IE 44350B1
Authority
IE
Ireland
Prior art keywords
compound
general formula
acid
ene
pregn
Prior art date
Application number
IE2083/76A
Other languages
English (en)
Other versions
IE44350L (en
Original Assignee
Searle & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Searle & Co filed Critical Searle & Co
Publication of IE44350L publication Critical patent/IE44350L/xx
Publication of IE44350B1 publication Critical patent/IE44350B1/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J21/00Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J21/001Lactones
    • C07J21/003Lactones at position 17
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10Antioedematous agents; Diuretics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J1/00Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003Androstane derivatives
    • C07J1/0033Androstane derivatives substituted in position 17 alfa and 17 beta
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/911Microorganisms using fungi

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IE2083/76A 1975-09-22 1976-09-21 6 ,17-dihydroxy-7a-(lower alkoxy)carbonyl-3-oxo-17a-pregn-4-ene-21-carboxylic acid -lactones and congeners IE44350B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/615,412 US3972871A (en) 1975-09-22 1975-09-22 6β,17-Dihydroxy-7α-(lower alkoxy)carbonyl-3-oxo-17α-pregn-4-ene-21-carboxylic acid γ-lactones and congeners

Publications (2)

Publication Number Publication Date
IE44350L IE44350L (en) 1977-03-22
IE44350B1 true IE44350B1 (en) 1981-11-04

Family

ID=24465262

Family Applications (1)

Application Number Title Priority Date Filing Date
IE2083/76A IE44350B1 (en) 1975-09-22 1976-09-21 6 ,17-dihydroxy-7a-(lower alkoxy)carbonyl-3-oxo-17a-pregn-4-ene-21-carboxylic acid -lactones and congeners

Country Status (21)

Country Link
US (1) US3972871A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JPS5248657A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AT (1) AT352305B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU (1) AU499083B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
BE (1) BE846437A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA1071620A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CH (1) CH623337A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE2642400A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DK (1) DK138995B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (1) ES451701A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FI (1) FI55670C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FR (1) FR2324309A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GB (1) GB1520948A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GR (1) GR61185B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IE (1) IE44350B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IL (1) IL50524A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NL (1) NL7610477A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NO (1) NO143910C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NZ (1) NZ182127A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PT (1) PT65616B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
SE (1) SE418295B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3972871A (en) * 1975-09-22 1976-08-03 G. D. Searle & Co. 6β,17-Dihydroxy-7α-(lower alkoxy)carbonyl-3-oxo-17α-pregn-4-ene-21-carboxylic acid γ-lactones and congeners
US4069219A (en) * 1976-12-27 1978-01-17 G. D. Searle & Co. 7ξ-(Alkoxycarbonyl)-6ξ-alkyl/halo-17-hydroxy-3-oxo-17α-pregn-4-ene-21-carboxylic acid γ-lactones and corresponding 21-carboxylic acids, their salts, and esters
JPS6063577U (ja) * 1983-10-07 1985-05-04 東レ株式会社 糸条のインタ−レ−ス装置
EP0973791B1 (en) * 1995-12-11 2007-06-20 G.D. Searle LLC. Process for the preparation of an epoxy compound
US6887991B1 (en) * 1996-12-11 2005-05-03 G. D. Searle & Company Processes for preparation of 9, 11-epoxy steroids and intermediates useful therein

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2237143A1 (de) * 1972-07-28 1974-02-14 Hoechst Ag Verfahren zur herstellung von beta(3-keto-7alpha-acetylthio-17beta-hydroxy4-androsten-17alpha-yl)-propionsaeuregamma-lacton und dessen 1-dehydro-derivat
GB1368006A (en) * 1972-08-24 1974-09-25 Searle & Co 4alpha,7alpha-carbonyl-5-cyano-17-hzydroxy-3-oxo-5beta,17alpha- pregnane-21-carboxylic acid ypsilon-lactone
US3972871A (en) * 1975-09-22 1976-08-03 G. D. Searle & Co. 6β,17-Dihydroxy-7α-(lower alkoxy)carbonyl-3-oxo-17α-pregn-4-ene-21-carboxylic acid γ-lactones and congeners

Also Published As

Publication number Publication date
PT65616A (en) 1976-10-01
JPS5248657A (en) 1977-04-18
FI55670C (fi) 1979-09-10
CH623337A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1981-05-29
ES451701A1 (es) 1978-01-01
FI762690A7 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1977-03-23
AT352305B (de) 1979-09-10
BE846437A (fr) 1977-03-22
FI55670B (fi) 1979-05-31
DK138995C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1979-05-14
NL7610477A (nl) 1977-03-24
NO143910C (no) 1981-06-03
GB1520948A (en) 1978-08-09
PT65616B (en) 1978-04-05
DK138995B (da) 1978-11-27
SE418295B (sv) 1981-05-18
SE7610449L (sv) 1977-03-23
DK425176A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1977-03-23
FR2324309B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1979-03-02
IL50524A (en) 1979-12-30
IL50524A0 (en) 1976-11-30
US3972871A (en) 1976-08-03
DE2642400A1 (de) 1977-03-24
ATA698476A (de) 1979-02-15
NZ182127A (en) 1978-11-13
NO143910B (no) 1981-01-26
CA1071620A (en) 1980-02-12
AU499083B2 (en) 1979-04-05
GR61185B (en) 1978-10-05
IE44350L (en) 1977-03-22
NO763231L (no) 1977-03-23
FR2324309A1 (fr) 1977-04-15
AU1796276A (en) 1978-04-06

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