DK1389241T3 - Polynucleotid-sekventeringsfremgangsmåde - Google Patents

Polynucleotid-sekventeringsfremgangsmåde

Info

Publication number
DK1389241T3
DK1389241T3 DK02727736T DK02727736T DK1389241T3 DK 1389241 T3 DK1389241 T3 DK 1389241T3 DK 02727736 T DK02727736 T DK 02727736T DK 02727736 T DK02727736 T DK 02727736T DK 1389241 T3 DK1389241 T3 DK 1389241T3
Authority
DK
Denmark
Prior art keywords
polynucleotide
enzyme
effect
linear
polynucleotide sequencing
Prior art date
Application number
DK02727736T
Other languages
Danish (da)
English (en)
Inventor
Daniel Henry Densham
Original Assignee
Medical Biosystems Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medical Biosystems Ltd filed Critical Medical Biosystems Ltd
Application granted granted Critical
Publication of DK1389241T3 publication Critical patent/DK1389241T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869Methods for sequencing
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
DK02727736T 2001-05-18 2002-05-20 Polynucleotid-sekventeringsfremgangsmåde DK1389241T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0112238.1A GB0112238D0 (en) 2001-05-18 2001-05-18 Sequencing method
PCT/GB2002/002345 WO2002095070A2 (en) 2001-05-18 2002-05-20 Polynucleotide sequencing method

Publications (1)

Publication Number Publication Date
DK1389241T3 true DK1389241T3 (da) 2008-05-26

Family

ID=9914926

Family Applications (1)

Application Number Title Priority Date Filing Date
DK02727736T DK1389241T3 (da) 2001-05-18 2002-05-20 Polynucleotid-sekventeringsfremgangsmåde

Country Status (21)

Country Link
US (3) US9476094B2 (pt)
EP (1) EP1389241B1 (pt)
JP (2) JP4094961B2 (pt)
KR (1) KR20030094412A (pt)
CN (1) CN1537172B (pt)
AT (1) ATE383442T1 (pt)
AU (1) AU2002257933B2 (pt)
BR (1) BR0209841A (pt)
CA (1) CA2447222C (pt)
DE (1) DE60224524T2 (pt)
DK (1) DK1389241T3 (pt)
ES (1) ES2299569T3 (pt)
GB (1) GB0112238D0 (pt)
HK (1) HK1061047A1 (pt)
IL (1) IL158743A0 (pt)
IS (1) IS7039A (pt)
MX (1) MXPA03010411A (pt)
NZ (1) NZ529349A (pt)
PT (1) PT1389241E (pt)
RU (1) RU2291197C2 (pt)
WO (1) WO2002095070A2 (pt)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2198221C2 (ru) * 1997-07-28 2003-02-10 Медикал Биосистемз Лтд. Способ секвенирования полинуклеотида и устройство для его осуществления
US7056661B2 (en) 1999-05-19 2006-06-06 Cornell Research Foundation, Inc. Method for sequencing nucleic acid molecules
GB9923644D0 (en) * 1999-10-06 1999-12-08 Medical Biosystems Ltd DNA sequencing
AU2002227156A1 (en) 2000-12-01 2002-06-11 Visigen Biotechnologies, Inc. Enzymatic nucleic acid synthesis: compositions and methods for altering monomer incorporation fidelity
GB0112238D0 (en) * 2001-05-18 2001-07-11 Medical Biosystems Ltd Sequencing method
US6852492B2 (en) * 2001-09-24 2005-02-08 Intel Corporation Nucleic acid sequencing by raman monitoring of uptake of precursors during molecular replication
US7361313B2 (en) * 2003-02-18 2008-04-22 Intel Corporation Methods for uniform metal impregnation into a nanoporous material
GB0317343D0 (en) 2003-07-24 2003-08-27 Medical Biosystems Ltd Polynucleotide sequencing
US7054528B2 (en) 2004-04-14 2006-05-30 Lucent Technologies Inc. Plasmon-enhanced tapered optical fibers
US7012687B2 (en) 2004-05-04 2006-03-14 Lucent Technologies Inc. Spectral analysis with evanescent field excitation
GB0413082D0 (en) * 2004-06-11 2004-07-14 Medical Biosystems Ltd Method
US7170050B2 (en) 2004-09-17 2007-01-30 Pacific Biosciences Of California, Inc. Apparatus and methods for optical analysis of molecules
SG169356A1 (en) * 2006-02-08 2011-03-30 Illumina Cambridge Ltd Method for sequencing a polynucleotide template
JP4890926B2 (ja) * 2006-04-28 2012-03-07 キヤノン株式会社 検出方法、およびキット
WO2007143034A1 (en) 2006-05-30 2007-12-13 University Of Utah Research Foundation Simultaneous amplification and detection if ribonucleic acid by an optical method using surface plasmon resonance
US8697138B2 (en) 2007-03-28 2014-04-15 Aker Biomarine As Methods of using krill oil to treat risk factors for cardiovascular, metabolic, and inflammatory disorders
ATE548643T1 (de) * 2007-03-30 2012-03-15 Pacific Biosciences California System und verfahren zur verstärkung von fluoreszenzsignalen
JP5222599B2 (ja) * 2007-07-20 2013-06-26 株式会社日立ハイテクノロジーズ 核酸分析デバイス及びそれを用いた核酸分析装置
US20100331195A1 (en) * 2007-10-04 2010-12-30 William Andregg Sequencing Nucleic Acid Polymers with Electron Microscopy
JP5175584B2 (ja) * 2008-03-13 2013-04-03 地方独立行政法人 東京都立産業技術研究センター 局所表面プラズモン共鳴イメージング装置
WO2009120372A2 (en) 2008-03-28 2009-10-01 Pacific Biosciences Of California, Inc. Compositions and methods for nucleic acid sequencing
US9182406B2 (en) 2008-08-04 2015-11-10 Biodesy, Inc. Nonlinear optical detection of molecules comprising an unnatural amino acid possessing a hyperpolarizability
JP5854350B2 (ja) * 2010-12-08 2016-02-09 公立大学法人大阪府立大学 金属ナノ粒子集積構造体を利用した圧力検出装置、温度検出装置、圧力検出方法、および温度検出方法
US9428789B2 (en) 2011-03-21 2016-08-30 Biodesy, Inc. Classification of kinase inhibitors using nonlinear optical techniques
US9279154B2 (en) 2011-12-21 2016-03-08 Illumina, Inc. Apparatus and methods for kinetic analysis and determination of nucleic acid sequences
WO2013115867A1 (en) 2012-02-05 2013-08-08 Biodesy, Llc Methods for identifying modulators of ras using nonlinear techniques
US20130288271A1 (en) 2012-04-25 2013-10-31 Biodesy, Llc Methods for detecting allosteric modulators of protein
US9395358B2 (en) 2012-02-05 2016-07-19 Biodesy, Inc. Methods for detecting allosteric modulators of protein
US9708656B2 (en) 2013-05-06 2017-07-18 Pacific Biosciences Of California, Inc. Real-time electronic sequencing
GB2531213B (en) 2014-06-30 2020-09-16 Biodesy Inc Systems and methods for high throughput analysis of conformation in biological entities
EP3237906B8 (en) 2014-12-23 2020-10-28 Bluelight Therapeutics, Inc. Attachment of proteins to interfaces for use in nonlinear optical detection
EP3278087A4 (en) 2015-04-02 2018-12-19 Biodesy, Inc. Methods for determining protein structure using a surface-selective nonlinear optical technique
WO2017014762A1 (en) * 2015-07-21 2017-01-26 Omniome, Inc. Nucleic acid sequencing methods and systems
US10077470B2 (en) 2015-07-21 2018-09-18 Omniome, Inc. Nucleic acid sequencing methods and systems
EP3455628A4 (en) 2016-05-09 2019-12-04 Biodesy, Inc. METHOD AND DEVICES FOR DETECTING INTERACTIONS OF PERIPHERAL MEMBRANE PROTEINS USING NONLINEAR OPTICAL TECHNIQUES
ES2917403T3 (es) 2017-01-06 2022-07-08 Illumina Inc Corrección de ajuste de fase
EP3592865A1 (en) * 2017-03-07 2020-01-15 Illumina, Inc. Single light source, two-optical channel sequencing
CN107064106B (zh) * 2017-04-11 2019-07-05 北京航空航天大学 一种二维表面等离子体最佳激发角位置的高精度识别方法
CN110511991A (zh) * 2019-09-11 2019-11-29 胡志刚 大规模dna芯片技术
GB2593729B (en) 2020-03-31 2022-05-11 Perkins Engines Co Ltd Spacer for use in an air intake system of an internal combustion chamber

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6048982A (en) * 1986-04-18 2000-04-11 Carnegie Mellon University Cyanine dyes as labeling reagents for detection of biological and other materials by luminescence methods
WO1995006138A1 (en) * 1993-08-25 1995-03-02 The Regents Of The University Of California Microscopic method for detecting micromotions
GB9508559D0 (en) 1995-04-27 1995-06-14 Polytech Transfer Ltd Surface second harmonic and sum-frequency generation immuno and enzyme assays
US5814516A (en) * 1995-10-13 1998-09-29 Lockheed Martin Energy Systems, Inc. Surface enhanced Raman gene probe and methods thereof
US6072043A (en) * 1996-06-04 2000-06-06 Polyprobe, Inc. Optimally fluorescent oligonucleotides
US5866430A (en) * 1996-06-13 1999-02-02 Grow; Ann E. Raman optrode processes and devices for detection of chemicals and microorganisms
EP0975796A4 (en) * 1997-03-05 2004-04-21 Anadys Pharmaceuticals Inc SELECTION PROCESS BASED ON ANISOTROPLE FLUORESCENCE FOR THE IDENTIFICATION OF COMPOUNDS WITH AFFINITY TO NUCLEIC ACIDS
US5958696A (en) * 1997-07-17 1999-09-28 Boehringer Ingelheim Pharmaceuticals, Inc. Quantitative solid phase helicase assay
RU2198221C2 (ru) * 1997-07-28 2003-02-10 Медикал Биосистемз Лтд. Способ секвенирования полинуклеотида и устройство для его осуществления
FR2771028A1 (fr) * 1997-11-18 1999-05-21 Total Sa Dispositif pour la separation des constituants d'un melange heterogene
US5786389A (en) * 1997-12-28 1998-07-28 Lambert Technologies Inc. Guerbet castor esters
WO1999044045A1 (en) 1998-02-27 1999-09-02 Massachusetts Institute Of Technology Single molecule detection with surface-enhanced raman scattering and applications in dna or rna sequencing
DE19816202A1 (de) * 1998-04-09 1999-10-14 Karl Seitz Raumkörper zur Errichtung von Bauwerken
JP4638043B2 (ja) * 1998-12-14 2011-02-23 パシフィック バイオサイエンシーズ オブ カリフォルニア, インコーポレイテッド ポリメラーゼ合成による、単一分子の核酸の配列決定のためのシステムおよび方法
DE60039037D1 (de) 1999-03-10 2008-07-10 Asm Scient Inc Methode zur direkten sequenzierung von nukleinsäuren
GB9907812D0 (en) * 1999-04-06 1999-06-02 Medical Biosystems Ltd Sequencing
US7056661B2 (en) 1999-05-19 2006-06-06 Cornell Research Foundation, Inc. Method for sequencing nucleic acid molecules
CA2377722A1 (en) * 1999-07-16 2001-01-25 Wm. Marsh Rice University Metal nanoshells for biosensing applications
WO2001016375A2 (en) * 1999-08-30 2001-03-08 The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services High speed parallel molecular nucleic acid sequencing
AU7714800A (en) * 1999-09-27 2001-04-30 Array Bioscience Corporation Fractal absorber for heat pipes with broad range heat radiation absorptivity
US6908736B1 (en) * 1999-10-06 2005-06-21 Medical Biosystems, Ltd. DNA sequencing method
GB9923644D0 (en) * 1999-10-06 1999-12-08 Medical Biosystems Ltd DNA sequencing
EP1358482A1 (en) * 2001-01-08 2003-11-05 Joshua S. Salafsky Method and apparatus using a surface-selective nonlinear optical technique
JP2004521323A (ja) * 2001-03-27 2004-07-15 サラフスカイ,ジョシュア,エス. 表面選択的非線形光学技法を使用してプローブ−ターゲット相互作用を検出する方法および装置
GB0112238D0 (en) * 2001-05-18 2001-07-11 Medical Biosystems Ltd Sequencing method
GB0317343D0 (en) * 2003-07-24 2003-08-27 Medical Biosystems Ltd Polynucleotide sequencing
GB0413082D0 (en) * 2004-06-11 2004-07-14 Medical Biosystems Ltd Method

Also Published As

Publication number Publication date
IS7039A (is) 2003-11-17
HK1061047A1 (en) 2004-09-03
US20040241678A1 (en) 2004-12-02
MXPA03010411A (es) 2004-06-25
JP4907498B2 (ja) 2012-03-28
CA2447222C (en) 2012-09-18
US20170022556A1 (en) 2017-01-26
ES2299569T3 (es) 2008-06-01
KR20030094412A (ko) 2003-12-11
CN1537172A (zh) 2004-10-13
US20090029383A1 (en) 2009-01-29
RU2291197C2 (ru) 2007-01-10
JP4094961B2 (ja) 2008-06-04
EP1389241A2 (en) 2004-02-18
GB0112238D0 (en) 2001-07-11
IL158743A0 (en) 2004-05-12
AU2002257933B2 (en) 2006-08-10
CN1537172B (zh) 2013-02-20
JP2004535800A (ja) 2004-12-02
CA2447222A1 (en) 2002-11-28
BR0209841A (pt) 2006-02-07
JP2008104463A (ja) 2008-05-08
US9476094B2 (en) 2016-10-25
ATE383442T1 (de) 2008-01-15
NZ529349A (en) 2006-10-27
WO2002095070A3 (en) 2003-09-18
DE60224524T2 (de) 2009-01-08
PT1389241E (pt) 2008-04-17
DE60224524D1 (de) 2008-02-21
EP1389241B1 (en) 2008-01-09
WO2002095070A2 (en) 2002-11-28
RU2003136429A (ru) 2005-05-27

Similar Documents

Publication Publication Date Title
DK1389241T3 (da) Polynucleotid-sekventeringsfremgangsmåde
EA200200428A1 (ru) Способ секвенирования днк
ES2316597T8 (es) Instrumentos analíticos, biosensores y métodos
DK244889D0 (da) Fremgangsmaade til bestemmelse af en analyt
DK0975807T3 (da) To-trins hybridisering og indfangning af et polynukleotid
DE60039905D1 (de) Enzyme enthaltende polymerische sensoren
ATE7900T1 (de) Chromogene verbindungen und ihre verwendung als enzymsubstrate.
DK0539477T3 (da) Fremgangsmåde til forstærkning af emissionssignalet af en luminescerende forbindelse
ATE514787T1 (de) Nachweis von proteasen
DE60045586D1 (de) Testverfahren zur messung der phosphorylierung
DK0690991T3 (da) Ny antikoagulant-cofaktor-aktivitet
DE602004030623D1 (de) Signal-Amplifikation mittels synthetischem Zymogen
ATE503021T1 (de) Verfahren zum nachweis von endoglykosidase aktivität
DE60026598D1 (de) Neue enzymatische substrate zum nachweis von pseudomonas aeruginosa
ATE280836T1 (de) Test zur gleichzeitigen messung von verschiedenen enzymatischen aktivitäten
ATE440964T1 (de) Verfahren zur detektion von polynukleotidkinase und deren verwendung als markierung
DE3850346D1 (de) Verfahren zur Selbstdurchführung von Enzymkinetik.
DE502006005169D1 (de) Diagnostisches Verfahren zur Erkennung von Trägern der Marburg l-Variante der Faktor VII-aktivierenden Protease (FSAP) anhand differenzieller Modulation der FSAP-Aktivität
FR2875242B1 (fr) Nouveaux substrats enzymatiques derives de phenoxazinone et leur utilisation comme revelateur dans la detection de microorganismes a activite peptidase
WO2003005028A8 (fr) Procede de selection d'agents bio-actifs par couplage de luminescence et systeme cellulaire vivant pour la mise en oeuvre de ce procede
DE60031963D1 (de) Nachweis einer msrv-1 induzierten superantigenaktivität in einer biologischen probe
ATE409742T1 (de) Von bacillus cereus produzierte cereulid-synthase,diese codierendes gen und verfahren zum nachweis von cereulid
ATE242483T1 (de) Chemosensitivitätsbestimmung über phosphatidylserin
ATE250140T1 (de) Chemosensitivitätsmessung über caspase-aktivität