DK138891C - Analogifremgangsmaade til fremstilling af 3-methyl-3-(3,4-dihydroxybenzyl)-piperazinderivater eller deres salte med fysiologisk anvendelige syrer - Google Patents

Analogifremgangsmaade til fremstilling af 3-methyl-3-(3,4-dihydroxybenzyl)-piperazinderivater eller deres salte med fysiologisk anvendelige syrer

Info

Publication number
DK138891C
DK138891C DK49077A DK49077A DK138891C DK 138891 C DK138891 C DK 138891C DK 49077 A DK49077 A DK 49077A DK 49077 A DK49077 A DK 49077A DK 138891 C DK138891 C DK 138891C
Authority
DK
Denmark
Prior art keywords
dihydroxybenzyl
salts
methyl
preparation
piperazine derivatives
Prior art date
Application number
DK49077A
Other languages
Danish (da)
English (en)
Other versions
DK49077A (da
DK138891B (da
Inventor
R Cyrus
M Raschack
Original Assignee
Knoll Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Knoll Ag filed Critical Knoll Ag
Publication of DK49077A publication Critical patent/DK49077A/da
Publication of DK138891B publication Critical patent/DK138891B/da
Application granted granted Critical
Publication of DK138891C publication Critical patent/DK138891C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/04—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/06—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members
    • C07D241/08—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
DK49077A 1976-02-07 1977-02-04 Analogifremgangsmaade til fremstilling af 3-methyl-3-(3,4-dihydroxybenzyl)-piperazinderivater eller deres salte med fysiologisk anvendelige syrer DK138891C (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19762604845 DE2604845A1 (de) 1976-02-07 1976-02-07 Neue piperazinderivate

Publications (3)

Publication Number Publication Date
DK49077A DK49077A (da) 1977-08-08
DK138891B DK138891B (da) 1978-11-13
DK138891C true DK138891C (da) 1979-04-23

Family

ID=5969327

Family Applications (1)

Application Number Title Priority Date Filing Date
DK49077A DK138891C (da) 1976-02-07 1977-02-04 Analogifremgangsmaade til fremstilling af 3-methyl-3-(3,4-dihydroxybenzyl)-piperazinderivater eller deres salte med fysiologisk anvendelige syrer

Country Status (25)

Country Link
US (1) US4079137A (xx)
JP (1) JPS52105186A (xx)
AT (1) AT355578B (xx)
AU (1) AU504526B2 (xx)
BE (1) BE850492A (xx)
CA (1) CA1094560A (xx)
CH (1) CH631448A5 (xx)
CS (1) CS201544B2 (xx)
DD (1) DD128133A5 (xx)
DE (1) DE2604845A1 (xx)
DK (1) DK138891C (xx)
ES (1) ES455691A1 (xx)
FI (1) FI63226C (xx)
FR (1) FR2340311A1 (xx)
GB (1) GB1550545A (xx)
HU (1) HU173483B (xx)
IE (1) IE44339B1 (xx)
IL (1) IL51316A (xx)
LU (1) LU76706A1 (xx)
NL (1) NL7700841A (xx)
NO (1) NO142625C (xx)
PL (1) PL105526B1 (xx)
PT (1) PT66154B (xx)
SE (1) SE7701187L (xx)
ZA (1) ZA77248B (xx)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4341698A (en) * 1979-06-21 1982-07-27 Richardson-Merrell Inc. Enkaphalin derivatives
US4483988A (en) * 1980-03-14 1984-11-20 Richardson Merrell Inc. Substituted derivatives of 4-t-alkoxycarbonyl-piperazin-2-ones
US4766125A (en) * 1981-06-23 1988-08-23 Janssen Pharmaceutica N.V. N-aryl-piperazinealkanamides useful for protecting hearts from myocardial injury caused by ischaemia, anoxia or hypoxia
EP1835931A4 (en) * 2004-12-06 2008-12-17 Sciclone Pharmaceuticals Inc ALPHA THYMOSINE PEPTIDES AS CANCER VACCINE ADJUVANTIES
US20080300166A1 (en) * 2007-06-01 2008-12-04 Sciclone Pharmaceuticals, Inc. Treatment of Melanoma with Alpha Thymosin Peptides
US20100330093A1 (en) * 2007-12-12 2010-12-30 Sciclone Pharmaceuticals, Inc. Treatment of melanoma with alpha thymosin peptides in combination with antibodies against cytotoxic t lymphocyte-associated antigen 4 (ctla4)
CA2708229A1 (en) * 2007-12-13 2009-06-18 Sciclone Pharmaceuticals, Inc. Treatment of melanoma with alpha thymosin peptides in combination with a kinase inhibitor
CA2708168A1 (en) * 2007-12-14 2009-06-25 Sciclone Pharmaceuticals, Inc. Treatment of melanoma with alpha thymosin peptides in combination with an antineoplastic heat shock apoptosis activator (hsaa)
US8829173B2 (en) 2008-09-26 2014-09-09 Tocagen Inc. Recombinant vectors
JP2012526149A (ja) * 2009-05-08 2012-10-25 サイクローン・ファーマシューティカルズ・インコーポレイテッド ワクチン増強剤としてのαチモシンペプチド
CA2962451C (en) 2014-10-21 2023-01-17 Sciclone Pharmaceuticals, Inc. Treatment of cancer with immune stimulators

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3472856A (en) * 1967-05-29 1969-10-14 Sterling Drug Inc 1-((thianaphthenyl)-lower-alkyl)-4-substituted-piperazines
DE2438725A1 (de) * 1974-08-12 1976-02-26 Knoll Ag Piperazinderivate
US4031216A (en) * 1974-08-12 1977-06-21 Knoll A.G. Chemische Fabriken 3-(3,4-Dialkoxy-benzyl)-3-methyl-piperazines

Also Published As

Publication number Publication date
CS201544B2 (en) 1980-11-28
NO142625B (no) 1980-06-09
AU2195277A (en) 1978-08-10
PT66154A (fr) 1977-03-01
IL51316A (en) 1980-12-31
DK49077A (da) 1977-08-08
AT355578B (de) 1980-03-10
FR2340311A1 (fr) 1977-09-02
ES455691A1 (es) 1978-01-01
DK138891B (da) 1978-11-13
SE7701187L (sv) 1977-08-08
NO142625C (no) 1980-09-17
BE850492A (fr) 1977-07-18
HU173483B (hu) 1979-05-28
ZA77248B (en) 1977-11-30
PL105526B1 (pl) 1979-10-31
PT66154B (fr) 1978-07-07
AU504526B2 (en) 1979-10-18
JPS52105186A (en) 1977-09-03
FI770398A (xx) 1977-08-08
FI63226B (fi) 1983-01-31
FR2340311B1 (xx) 1980-02-08
GB1550545A (en) 1979-08-15
NL7700841A (nl) 1977-08-09
US4079137A (en) 1978-03-14
DD128133A5 (de) 1977-11-02
FI63226C (fi) 1983-05-10
LU76706A1 (xx) 1977-06-28
IE44339L (en) 1977-08-07
DE2604845A1 (de) 1977-08-18
CH631448A5 (de) 1982-08-13
ATA68177A (de) 1979-08-15
CA1094560A (en) 1981-01-27
IE44339B1 (en) 1981-10-21
NO770374L (no) 1977-08-09
IL51316A0 (en) 1977-03-31

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