DK138891B - Analogifremgangsm de til fremstilling af 3-methyl-3-(3,4-dihydroxybenzyl)-piperazinderivater eller deres salte med fysiologisk anvendelige syrer - Google Patents
Analogifremgangsm de til fremstilling af 3-methyl-3-(3,4-dihydroxybenzyl)-piperazinderivater eller deres salte med fysiologisk anvendelige syrerInfo
- Publication number
- DK138891B DK138891B DK49077AA DK49077A DK138891B DK 138891 B DK138891 B DK 138891B DK 49077A A DK49077A A DK 49077AA DK 49077 A DK49077 A DK 49077A DK 138891 B DK138891 B DK 138891B
- Authority
- DK
- Denmark
- Prior art keywords
- dihydroxybenzyl
- analogical
- procedures
- salts
- methyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/04—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/06—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members
- C07D241/08—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- General Health & Medical Sciences (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19762604845 DE2604845A1 (de) | 1976-02-07 | 1976-02-07 | Neue piperazinderivate |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| DK49077A DK49077A (da) | 1977-08-08 |
| DK138891B true DK138891B (da) | 1978-11-13 |
| DK138891C DK138891C (da) | 1979-04-23 |
Family
ID=5969327
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK49077A DK138891C (da) | 1976-02-07 | 1977-02-04 | Analogifremgangsmaade til fremstilling af 3-methyl-3-(3,4-dihydroxybenzyl)-piperazinderivater eller deres salte med fysiologisk anvendelige syrer |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US4079137A (da) |
| JP (1) | JPS52105186A (da) |
| AT (1) | AT355578B (da) |
| AU (1) | AU504526B2 (da) |
| BE (1) | BE850492A (da) |
| CA (1) | CA1094560A (da) |
| CH (1) | CH631448A5 (da) |
| CS (1) | CS201544B2 (da) |
| DD (1) | DD128133A5 (da) |
| DE (1) | DE2604845A1 (da) |
| DK (1) | DK138891C (da) |
| ES (1) | ES455691A1 (da) |
| FI (1) | FI63226C (da) |
| FR (1) | FR2340311A1 (da) |
| GB (1) | GB1550545A (da) |
| HU (1) | HU173483B (da) |
| IE (1) | IE44339B1 (da) |
| IL (1) | IL51316A (da) |
| LU (1) | LU76706A1 (da) |
| NL (1) | NL7700841A (da) |
| NO (1) | NO142625C (da) |
| PL (1) | PL105526B1 (da) |
| PT (1) | PT66154B (da) |
| SE (1) | SE7701187L (da) |
| ZA (1) | ZA77248B (da) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4341698A (en) * | 1979-06-21 | 1982-07-27 | Richardson-Merrell Inc. | Enkaphalin derivatives |
| US4483988A (en) * | 1980-03-14 | 1984-11-20 | Richardson Merrell Inc. | Substituted derivatives of 4-t-alkoxycarbonyl-piperazin-2-ones |
| US4766125A (en) * | 1981-06-23 | 1988-08-23 | Janssen Pharmaceutica N.V. | N-aryl-piperazinealkanamides useful for protecting hearts from myocardial injury caused by ischaemia, anoxia or hypoxia |
| AU2005314271B2 (en) | 2004-12-06 | 2011-06-16 | Sciclone Pharmaceuticals, Inc. | Alpha thymosin peptides as cancer vaccine adjuvants |
| US20080300166A1 (en) * | 2007-06-01 | 2008-12-04 | Sciclone Pharmaceuticals, Inc. | Treatment of Melanoma with Alpha Thymosin Peptides |
| EP2240195A4 (en) * | 2007-12-12 | 2011-12-21 | Sciclone Pharmaceuticals Inc | TREATMENT OF MELANOMA WITH ALPHA-THYMOSIN PEPTIDES IN ASSOCIATION WITH ANTIBODIES AGAINST ANTIGEN 4 ASSOCIATED WITH CYTOTOXIC LYMPHOCYTE T (CTLA4) |
| CA2708229A1 (en) * | 2007-12-13 | 2009-06-18 | Sciclone Pharmaceuticals, Inc. | Treatment of melanoma with alpha thymosin peptides in combination with a kinase inhibitor |
| EP2230908A1 (en) * | 2007-12-14 | 2010-09-29 | Sciclone Pharmaceuticals, Inc. | Treatment of melanoma with alpha thymosin peptides in combination with an antineoplastic heat shock apoptosis activator (hsaa) |
| US8829173B2 (en) | 2008-09-26 | 2014-09-09 | Tocagen Inc. | Recombinant vectors |
| WO2010129947A2 (en) * | 2009-05-08 | 2010-11-11 | Sciclone Pharmaceuticals, Inc. | Alpha thymosin peptides as vaccine enhancers |
| CN113855806A (zh) | 2014-10-21 | 2021-12-31 | 赛生药品股份国际有限公司 | 用免疫刺激剂治疗癌症 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3472856A (en) * | 1967-05-29 | 1969-10-14 | Sterling Drug Inc | 1-((thianaphthenyl)-lower-alkyl)-4-substituted-piperazines |
| US4031216A (en) * | 1974-08-12 | 1977-06-21 | Knoll A.G. Chemische Fabriken | 3-(3,4-Dialkoxy-benzyl)-3-methyl-piperazines |
| DE2438725A1 (de) * | 1974-08-12 | 1976-02-26 | Knoll Ag | Piperazinderivate |
-
1976
- 1976-02-07 DE DE19762604845 patent/DE2604845A1/de not_active Withdrawn
-
1977
- 1977-01-17 ZA ZA770248A patent/ZA77248B/xx unknown
- 1977-01-18 BE BE174169A patent/BE850492A/xx not_active IP Right Cessation
- 1977-01-19 US US05/760,722 patent/US4079137A/en not_active Expired - Lifetime
- 1977-01-24 GB GB2736/77A patent/GB1550545A/en not_active Expired
- 1977-01-24 IL IL51316A patent/IL51316A/xx unknown
- 1977-01-27 NL NL7700841A patent/NL7700841A/xx not_active Application Discontinuation
- 1977-02-01 IE IE205/77A patent/IE44339B1/en unknown
- 1977-02-03 SE SE7701187A patent/SE7701187L/xx not_active Application Discontinuation
- 1977-02-03 AT AT68177A patent/AT355578B/de not_active IP Right Cessation
- 1977-02-03 CS CS77726A patent/CS201544B2/cs unknown
- 1977-02-03 CH CH132077A patent/CH631448A5/de not_active IP Right Cessation
- 1977-02-04 HU HU77KO2845A patent/HU173483B/hu unknown
- 1977-02-04 AU AU21952/77A patent/AU504526B2/en not_active Expired
- 1977-02-04 CA CA271,087A patent/CA1094560A/en not_active Expired
- 1977-02-04 DD DD7700197240A patent/DD128133A5/xx unknown
- 1977-02-04 DK DK49077A patent/DK138891C/da active
- 1977-02-04 LU LU76706A patent/LU76706A1/xx unknown
- 1977-02-04 PT PT66154A patent/PT66154B/pt unknown
- 1977-02-04 NO NO770374A patent/NO142625C/no unknown
- 1977-02-04 PL PL1977195809A patent/PL105526B1/pl unknown
- 1977-02-05 ES ES455691A patent/ES455691A1/es not_active Expired
- 1977-02-07 FI FI770398A patent/FI63226C/fi not_active IP Right Cessation
- 1977-02-07 FR FR7703386A patent/FR2340311A1/fr active Granted
- 1977-02-07 JP JP1235677A patent/JPS52105186A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CH631448A5 (de) | 1982-08-13 |
| DK138891C (da) | 1979-04-23 |
| IL51316A0 (en) | 1977-03-31 |
| DK49077A (da) | 1977-08-08 |
| DE2604845A1 (de) | 1977-08-18 |
| PL105526B1 (pl) | 1979-10-31 |
| BE850492A (fr) | 1977-07-18 |
| AU2195277A (en) | 1978-08-10 |
| IE44339B1 (en) | 1981-10-21 |
| PT66154B (fr) | 1978-07-07 |
| SE7701187L (sv) | 1977-08-08 |
| FI770398A (da) | 1977-08-08 |
| ES455691A1 (es) | 1978-01-01 |
| NO142625B (no) | 1980-06-09 |
| LU76706A1 (da) | 1977-06-28 |
| IE44339L (en) | 1977-08-07 |
| FR2340311B1 (da) | 1980-02-08 |
| AU504526B2 (en) | 1979-10-18 |
| CS201544B2 (en) | 1980-11-28 |
| GB1550545A (en) | 1979-08-15 |
| HU173483B (hu) | 1979-05-28 |
| JPS52105186A (en) | 1977-09-03 |
| US4079137A (en) | 1978-03-14 |
| FI63226B (fi) | 1983-01-31 |
| CA1094560A (en) | 1981-01-27 |
| NO770374L (no) | 1977-08-09 |
| ZA77248B (en) | 1977-11-30 |
| FR2340311A1 (fr) | 1977-09-02 |
| DD128133A5 (de) | 1977-11-02 |
| PT66154A (fr) | 1977-03-01 |
| ATA68177A (de) | 1979-08-15 |
| IL51316A (en) | 1980-12-31 |
| AT355578B (de) | 1980-03-10 |
| NL7700841A (nl) | 1977-08-09 |
| NO142625C (no) | 1980-09-17 |
| FI63226C (fi) | 1983-05-10 |
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