DK148035C - Analogifremgangsmaade til fremstilling af 4''-substituerede aminoderivater af oleandomycin eller salte deraf med syrer - Google Patents

Analogifremgangsmaade til fremstilling af 4''-substituerede aminoderivater af oleandomycin eller salte deraf med syrer

Info

Publication number
DK148035C
DK148035C DK51678A DK51678A DK148035C DK 148035 C DK148035 C DK 148035C DK 51678 A DK51678 A DK 51678A DK 51678 A DK51678 A DK 51678A DK 148035 C DK148035 C DK 148035C
Authority
DK
Denmark
Prior art keywords
oleandomycine
salts
acids
preparation
substituted amino
Prior art date
Application number
DK51678A
Other languages
English (en)
Other versions
DK51678A (da
DK148035B (da
Inventor
Robert Fischer Myers
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of DK51678A publication Critical patent/DK51678A/da
Priority to DK214482A priority Critical patent/DK214482A/da
Publication of DK148035B publication Critical patent/DK148035B/da
Application granted granted Critical
Publication of DK148035C publication Critical patent/DK148035C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/70—Sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
DK51678A 1977-02-04 1978-02-03 Analogifremgangsmaade til fremstilling af 4''-substituerede aminoderivater af oleandomycin eller salte deraf med syrer DK148035C (da)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DK214482A DK214482A (da) 1977-02-04 1982-05-12 Mellemprodukt til fremstilling af 4"-deoxy-4"-substituerede aminooleandomyciner

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US05/765,488 US4085119A (en) 1977-02-04 1977-02-04 4-Substituted amino derivatives of oleandomycin
US76548877 1977-02-04

Publications (3)

Publication Number Publication Date
DK51678A DK51678A (da) 1978-08-05
DK148035B DK148035B (da) 1985-02-11
DK148035C true DK148035C (da) 1985-07-15

Family

ID=25073690

Family Applications (1)

Application Number Title Priority Date Filing Date
DK51678A DK148035C (da) 1977-02-04 1978-02-03 Analogifremgangsmaade til fremstilling af 4''-substituerede aminoderivater af oleandomycin eller salte deraf med syrer

Country Status (11)

Country Link
US (2) US4085119A (da)
JP (1) JPS5398983A (da)
BE (1) BE863620A (da)
DE (1) DE2804517C3 (da)
DK (1) DK148035C (da)
FR (1) FR2379551A1 (da)
GB (1) GB1593644A (da)
IE (1) IE46394B1 (da)
IT (1) IT1094210B (da)
LU (1) LU79005A1 (da)
NL (1) NL171588C (da)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4189590A (en) * 1976-08-06 1980-02-19 Pfizer Inc. Semi-synthetic oleandomycin derivatives--C8 modifications
US4133950A (en) * 1978-01-03 1979-01-09 Pfizer Inc. 4"-Deoxy-4"-carbamate and dithiocarbamate derivatives of oleandomycin and its esters
US4166901A (en) * 1978-01-03 1979-09-04 Pfizer Inc. 4"-Deoxy-4"-arylglyoxamido- and aroylthioformamido derivatives of oleandomycin and its esters
US4180654A (en) * 1978-01-03 1979-12-25 Pfizer Inc. 4"-Deoxy-4"-acylamido derivatives of oleandomycin, erythromycin and erythromycin carbonate
US4124755A (en) * 1978-01-03 1978-11-07 Pfizer Inc. 11-Alkanoyl-4"-deoxy-4"-isonitrilo-oleandomycin derivatives
US4316010A (en) * 1981-01-02 1982-02-16 Pfizer Inc. Cis-C3 "C4 "-carbonate derivatives of O-demethyloleandomycin and intermediates therefor
IT1169013B (it) 1981-01-09 1987-05-20 Pierrel Spa Composti macrolidici ad attivita' antibiotica, procedimento e microorganismo per la loro preparazione e relative composizioni farmaceutiche
US4336368A (en) * 1981-04-20 1982-06-22 Pfizer Inc. 4 Deoxy-4-methylene oleandomycin and derivatives thereof
US4427663A (en) 1982-03-16 1984-01-24 Merck & Co., Inc. 4"-Keto-and 4"-amino-4"-deoxy avermectin compounds and substituted amino derivatives thereof
US4808590A (en) * 1987-07-17 1989-02-28 Harbor Branch Oceanographic Institution, Inc. Antiviral, antitumor and antifungal compositions and their methods of use

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2870138A (en) * 1953-08-13 1959-01-20 Upjohn Co Erythromycin salts
US3357999A (en) * 1965-12-23 1967-12-12 Abbott Lab Anhydrotriacetylerythronolide b
US3842068A (en) * 1972-06-15 1974-10-15 Abbott Lab 8-epi-erythromycins
US3836519A (en) * 1973-05-04 1974-09-17 Abbott Lab Sulfonyl derivatives of erythromycin
US3928387A (en) * 1974-02-04 1975-12-23 Hoffmann La Roche Antibiotic 1745A/X and methods for the production thereof
US3963696A (en) * 1975-02-21 1976-06-15 Abbott Laboratories 6,6A-AND 6,7-Anhydroerythromycin B and derivatives thereof
US4036853A (en) * 1976-08-06 1977-07-19 Pfizer Inc. Semi-synthetic oleandomycin derivatives-C8 modifications

Also Published As

Publication number Publication date
DK51678A (da) 1978-08-05
IT7820007A0 (it) 1978-02-03
GB1593644A (en) 1981-07-22
FR2379551A1 (fr) 1978-09-01
NL171588C (nl) 1983-04-18
NL171588B (nl) 1982-11-16
IE46394B1 (en) 1983-06-01
NL7801261A (nl) 1978-08-08
US4085119A (en) 1978-04-18
US4140848A (en) 1979-02-20
IE780234L (en) 1978-08-04
FR2379551B1 (da) 1980-08-29
DK148035B (da) 1985-02-11
JPS5628918B2 (da) 1981-07-04
DE2804517C3 (de) 1981-05-07
IT1094210B (it) 1985-07-26
LU79005A1 (fr) 1979-09-06
DE2804517A1 (de) 1978-08-10
JPS5398983A (en) 1978-08-29
BE863620A (fr) 1978-08-03
DE2804517B2 (de) 1980-09-25

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PBP Patent lapsed