DK1381431T3 - Aromatase-inhibition for at foröge implantationsrate - Google Patents

Aromatase-inhibition for at foröge implantationsrate

Info

Publication number
DK1381431T3
DK1381431T3 DK02717917T DK02717917T DK1381431T3 DK 1381431 T3 DK1381431 T3 DK 1381431T3 DK 02717917 T DK02717917 T DK 02717917T DK 02717917 T DK02717917 T DK 02717917T DK 1381431 T3 DK1381431 T3 DK 1381431T3
Authority
DK
Denmark
Prior art keywords
implantation rate
aromatase inhibition
increase implantation
increase
aromatase
Prior art date
Application number
DK02717917T
Other languages
Danish (da)
English (en)
Inventor
Robert F Casper
Mohamed F M Mitwally
Original Assignee
Ares Trading Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ares Trading Sa filed Critical Ares Trading Sa
Application granted granted Critical
Publication of DK1381431T3 publication Critical patent/DK1381431T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4196—1,2,4-Triazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A61K31/5685—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone having an oxo group in position 17, e.g. androsterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/24—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g. HCG; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/32—Antioestrogens
DK02717917T 2001-04-17 2002-04-17 Aromatase-inhibition for at foröge implantationsrate DK1381431T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US28417801P 2001-04-17 2001-04-17
PCT/CA2002/000522 WO2002083240A1 (en) 2001-04-17 2002-04-17 Aromatase inhibition to enhance assisted reproduction

Publications (1)

Publication Number Publication Date
DK1381431T3 true DK1381431T3 (da) 2007-10-08

Family

ID=23089175

Family Applications (1)

Application Number Title Priority Date Filing Date
DK02717917T DK1381431T3 (da) 2001-04-17 2002-04-17 Aromatase-inhibition for at foröge implantationsrate

Country Status (33)

Country Link
US (1) US7846957B2 (cs)
EP (1) EP1381431B1 (cs)
JP (1) JP2004526764A (cs)
KR (1) KR20040012751A (cs)
CN (1) CN100377710C (cs)
AR (1) AR034310A1 (cs)
AT (1) ATE363906T1 (cs)
AU (1) AU2002249041B2 (cs)
BG (1) BG108316A (cs)
BR (1) BR0208968A (cs)
CA (1) CA2444932A1 (cs)
CY (1) CY1108021T1 (cs)
CZ (1) CZ299735B6 (cs)
DE (1) DE60220516T2 (cs)
DK (1) DK1381431T3 (cs)
EA (1) EA010354B1 (cs)
EE (1) EE200300512A (cs)
ES (1) ES2283541T3 (cs)
HK (1) HK1067987A1 (cs)
HR (1) HRP20030838A2 (cs)
HU (1) HUP0303795A2 (cs)
IL (2) IL158395A0 (cs)
MX (1) MXPA03009446A (cs)
NO (1) NO20034245L (cs)
NZ (1) NZ528501A (cs)
PL (1) PL366554A1 (cs)
PT (1) PT1381431E (cs)
SI (1) SI1381431T1 (cs)
SK (1) SK14252003A3 (cs)
UA (1) UA79591C2 (cs)
WO (1) WO2002083240A1 (cs)
YU (1) YU81303A (cs)
ZA (1) ZA200307514B (cs)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MXPA05000251A (es) * 2002-07-02 2005-07-15 Pharmacia & Upjohn Co Llc Tratamiento de la infertilidad con exemestano.
NZ603548A (en) * 2010-05-20 2014-06-27 Univ Saskatchewan Use of aromatase inhibitors for synchronizing ovulation, inducing superovulation or double ovulation and improving twinning and fertility in a mammal
WO2012127501A2 (en) * 2011-03-11 2012-09-27 Sanzyme Limited Composition for improving endometrial thickness during ovarian stimulation
US9295668B2 (en) 2011-09-08 2016-03-29 Merco BioPharma 2 Limited Use of an aromatase inhibitor for the treatment of hypogonadism and related diseases
WO2014169395A1 (en) 2013-04-19 2014-10-23 University Of Saskatchewan Aromatase inhibitor-releasing intravaginal device
CN107648594A (zh) * 2017-11-08 2018-02-02 广州市桐晖药业有限公司 枸橼酸氯米芬胶囊及其制备方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4289762A (en) * 1980-06-27 1981-09-15 Merrell Dow Pharmaceuticals Inc. 10-(1,2-Propadienyl) steroids as irreversible aromatase inhibitors
US4728645A (en) * 1982-12-21 1988-03-01 Ciba-Geigy Corporation Substituted imidazo[1,5-A]pyridine derivatives and other substituted bicyclic derivatives, useful as aromatase inhibitors
US4845227A (en) * 1984-06-18 1989-07-04 Eli Lilly And Company Aromatase inhibitors from azoles
US4978672A (en) * 1986-03-07 1990-12-18 Ciba-Geigy Corporation Alpha-heterocyclc substituted tolunitriles
DE4330237C2 (de) * 1993-09-02 1995-11-30 Schering Ag 1-Methylsubstituierte Androsta-1,4-dien-3,17-dione, Verfahren zu deren Herstellung und diese enthaltende pharmazeutische Präparate
DE59703511D1 (de) 1996-03-29 2001-06-13 S W Patentverwaltungs Ges M B Kosmetikum bzw. kosmetikzusammensetzung zur glättung und straffung der haut bei gestörtem unterhaut-binde-fettgewebe, insbesondere bei der "cellulite"
WO1997040846A1 (en) 1996-04-30 1997-11-06 Takeda Chemical Industries, Ltd. COMBINED USE OF GnRH AGONIST AND ANTAGONIST
DE19622457A1 (de) 1996-05-24 1997-11-27 Schering Ag 7alpha-(5-Methylaminopentyl)-estratriene, Verfahren zu deren Herstellung, pharmazeutische Präparate, die diese 7alpha-(5-Methylaminopentyl)-estratriene enthalten sowie deren Verwendung zur Herstellung von Arzneimitteln
EP0994718B1 (en) * 1997-06-20 2005-08-17 Akzo Nobel N.V. Gonadotropin releasing hormone antagonist
US6953774B2 (en) * 2000-08-11 2005-10-11 Applied Research Systems Ars Holding N.V. Methods of inducing ovulation

Also Published As

Publication number Publication date
US20040204393A1 (en) 2004-10-14
HUP0303795A2 (hu) 2004-03-29
CZ20033108A3 (en) 2004-06-16
SK14252003A3 (sk) 2004-03-02
CY1108021T1 (el) 2013-09-04
HK1067987A1 (en) 2005-04-22
EA200301129A1 (ru) 2004-04-29
CZ299735B6 (cs) 2008-11-05
MXPA03009446A (es) 2004-05-24
UA79591C2 (en) 2007-07-10
PT1381431E (pt) 2007-07-03
DE60220516T2 (de) 2007-10-11
ATE363906T1 (de) 2007-06-15
NO20034245D0 (no) 2003-09-23
AR034310A1 (es) 2004-02-18
AU2002249041B2 (en) 2007-07-12
BR0208968A (pt) 2004-04-27
PL366554A1 (en) 2005-02-07
EP1381431A1 (en) 2004-01-21
CN1549734A (zh) 2004-11-24
ZA200307514B (en) 2004-09-27
ES2283541T3 (es) 2007-11-01
CA2444932A1 (en) 2002-10-24
EE200300512A (et) 2004-02-16
BG108316A (bg) 2004-12-30
NZ528501A (en) 2008-04-30
NO20034245L (no) 2003-12-15
SI1381431T1 (sl) 2007-08-31
EP1381431B1 (en) 2007-06-06
KR20040012751A (ko) 2004-02-11
WO2002083240A1 (en) 2002-10-24
US7846957B2 (en) 2010-12-07
CN100377710C (zh) 2008-04-02
IL158395A0 (en) 2004-05-12
IL158395A (en) 2009-06-15
HRP20030838A2 (en) 2005-08-31
EA010354B1 (ru) 2008-08-29
WO2002083240A9 (en) 2004-05-06
JP2004526764A (ja) 2004-09-02
YU81303A (sh) 2006-05-25
DE60220516D1 (de) 2007-07-19

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