MXPA03009446A - Inhibicion de aromatasa para mejorar reproduccion asistida. - Google Patents
Inhibicion de aromatasa para mejorar reproduccion asistida.Info
- Publication number
- MXPA03009446A MXPA03009446A MXPA03009446A MXPA03009446A MXPA03009446A MX PA03009446 A MXPA03009446 A MX PA03009446A MX PA03009446 A MXPA03009446 A MX PA03009446A MX PA03009446 A MXPA03009446 A MX PA03009446A MX PA03009446 A MXPA03009446 A MX PA03009446A
- Authority
- MX
- Mexico
- Prior art keywords
- assisted reproduction
- enhance
- aromatase inhibition
- aromatase inhibitor
- cycles
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4196—1,2,4-Triazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
- A61K31/5685—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone having an oxo group in position 17, e.g. androsterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/24—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g. HCG; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/32—Antioestrogens
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Endocrinology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Reproductive Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Diabetes (AREA)
- Gynecology & Obstetrics (AREA)
- Pregnancy & Childbirth (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
La presente invencion se refiere al uso de cuando menos un inhibidor de aromatasa en la produccion de un medicamento para mejorar los indices de implantacion y embarazo, en hembras sometidas a tratamiento de reproduccion asistida, el cual comprende una o mas dosis diarias de un inhibidor de aromatasa (AI) administrado durante el ciclo de reproduccion asistida o ciclos de estimulacion ovarica, en donde las dosis de AI se seleccionan del grupo que consiste de cantidades efectivas para reducir los niveles de estradiol en el suero. Tambien se describen preparaciones y paquetes farmaceuticos relacionados.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US28417801P | 2001-04-17 | 2001-04-17 | |
| PCT/CA2002/000522 WO2002083240A1 (en) | 2001-04-17 | 2002-04-17 | Aromatase inhibition to enhance assisted reproduction |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MXPA03009446A true MXPA03009446A (es) | 2004-05-24 |
Family
ID=23089175
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MXPA03009446A MXPA03009446A (es) | 2001-04-17 | 2002-04-17 | Inhibicion de aromatasa para mejorar reproduccion asistida. |
Country Status (33)
| Country | Link |
|---|---|
| US (1) | US7846957B2 (es) |
| EP (1) | EP1381431B1 (es) |
| JP (1) | JP2004526764A (es) |
| KR (1) | KR20040012751A (es) |
| CN (1) | CN100377710C (es) |
| AR (1) | AR034310A1 (es) |
| AT (1) | ATE363906T1 (es) |
| AU (1) | AU2002249041B2 (es) |
| BG (1) | BG108316A (es) |
| BR (1) | BR0208968A (es) |
| CA (1) | CA2444932A1 (es) |
| CY (1) | CY1108021T1 (es) |
| CZ (1) | CZ299735B6 (es) |
| DE (1) | DE60220516T2 (es) |
| DK (1) | DK1381431T3 (es) |
| EA (1) | EA010354B1 (es) |
| EE (1) | EE200300512A (es) |
| ES (1) | ES2283541T3 (es) |
| HK (1) | HK1067987A1 (es) |
| HR (1) | HRP20030838A2 (es) |
| HU (1) | HUP0303795A2 (es) |
| IL (2) | IL158395A0 (es) |
| MX (1) | MXPA03009446A (es) |
| NO (1) | NO20034245L (es) |
| NZ (1) | NZ528501A (es) |
| PL (1) | PL366554A1 (es) |
| PT (1) | PT1381431E (es) |
| SI (1) | SI1381431T1 (es) |
| SK (1) | SK14252003A3 (es) |
| UA (1) | UA79591C2 (es) |
| WO (1) | WO2002083240A1 (es) |
| YU (1) | YU81303A (es) |
| ZA (1) | ZA200307514B (es) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR0312393A (pt) * | 2002-07-02 | 2005-04-12 | Pharmacia & Upjohn Co Llc | Tratamento de infertilidade com exemestano |
| EP2571504A4 (en) * | 2010-05-20 | 2013-11-06 | Univ Saskatchewan | USE OF AROMATASE INHIBITORS FOR SYNCHRONIZED EASPING, FOR MAKING MULTIPLE OR DOUBLE EISPRUS, AND FOR INCREASING TWINING AND FRUITABILITY OF MAMMALS |
| WO2012127501A2 (en) * | 2011-03-11 | 2012-09-27 | Sanzyme Limited | Composition for improving endometrial thickness during ovarian stimulation |
| BR112014005434B1 (pt) | 2011-09-08 | 2021-01-05 | Novartis Ag | Composições farmacêuticas compreendendo inibidor da aromatase 4,4'-[fluoro-(1h-1,2,4triazol-1-il)metilemo]bisbenzonitrila e seu método de preparação |
| BR112015026298A8 (pt) | 2013-04-19 | 2019-12-24 | Univ Saskatchewan | veículo de dispensação para a dispensação de um inibidor da aromatase |
| CN107648594A (zh) * | 2017-11-08 | 2018-02-02 | 广州市桐晖药业有限公司 | 枸橼酸氯米芬胶囊及其制备方法 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4289762A (en) * | 1980-06-27 | 1981-09-15 | Merrell Dow Pharmaceuticals Inc. | 10-(1,2-Propadienyl) steroids as irreversible aromatase inhibitors |
| US4728645A (en) * | 1982-12-21 | 1988-03-01 | Ciba-Geigy Corporation | Substituted imidazo[1,5-A]pyridine derivatives and other substituted bicyclic derivatives, useful as aromatase inhibitors |
| US4845227A (en) * | 1984-06-18 | 1989-07-04 | Eli Lilly And Company | Aromatase inhibitors from azoles |
| US4978672A (en) * | 1986-03-07 | 1990-12-18 | Ciba-Geigy Corporation | Alpha-heterocyclc substituted tolunitriles |
| DE4330237C2 (de) * | 1993-09-02 | 1995-11-30 | Schering Ag | 1-Methylsubstituierte Androsta-1,4-dien-3,17-dione, Verfahren zu deren Herstellung und diese enthaltende pharmazeutische Präparate |
| ATE200978T1 (de) | 1996-03-29 | 2001-05-15 | S W Patentverwertungs Ges M B | KOSMETIKUM BZW. KOSMETIKZUSAMMENSETZUNG ZUR GLÄTTUNG UND STRAFFUNG DER HAUT BEI GESTÖRTEM UNTERHAUT-BINDE-FETTGEWEBE, INSBESONDERE BEI DER ßCELLULITEß |
| US6015789A (en) * | 1996-04-30 | 2000-01-18 | Takeda Chemical Industries, Ltd. | Combined use of GnRH agonist and antagonist |
| DE19622457A1 (de) | 1996-05-24 | 1997-11-27 | Schering Ag | 7alpha-(5-Methylaminopentyl)-estratriene, Verfahren zu deren Herstellung, pharmazeutische Präparate, die diese 7alpha-(5-Methylaminopentyl)-estratriene enthalten sowie deren Verwendung zur Herstellung von Arzneimitteln |
| ES2247710T3 (es) * | 1997-06-20 | 2006-03-01 | Akzo Nobel N.V. | Antagonista de gonadotropina. |
| US6953774B2 (en) * | 2000-08-11 | 2005-10-11 | Applied Research Systems Ars Holding N.V. | Methods of inducing ovulation |
-
2002
- 2002-04-17 YU YU81303A patent/YU81303A/sh unknown
- 2002-04-17 KR KR10-2003-7013483A patent/KR20040012751A/ko not_active Application Discontinuation
- 2002-04-17 SI SI200230565T patent/SI1381431T1/sl unknown
- 2002-04-17 EP EP02717917A patent/EP1381431B1/en not_active Expired - Lifetime
- 2002-04-17 HU HU0303795A patent/HUP0303795A2/hu unknown
- 2002-04-17 UA UA20031110267A patent/UA79591C2/uk unknown
- 2002-04-17 AU AU2002249041A patent/AU2002249041B2/en not_active Ceased
- 2002-04-17 JP JP2002581040A patent/JP2004526764A/ja active Pending
- 2002-04-17 CN CNB028123190A patent/CN100377710C/zh not_active Expired - Fee Related
- 2002-04-17 WO PCT/CA2002/000522 patent/WO2002083240A1/en active IP Right Grant
- 2002-04-17 DK DK02717917T patent/DK1381431T3/da active
- 2002-04-17 IL IL15839502A patent/IL158395A0/xx unknown
- 2002-04-17 NZ NZ528501A patent/NZ528501A/en not_active IP Right Cessation
- 2002-04-17 EA EA200301129A patent/EA010354B1/ru not_active IP Right Cessation
- 2002-04-17 PL PL02366554A patent/PL366554A1/xx not_active Application Discontinuation
- 2002-04-17 EE EEP200300512A patent/EE200300512A/xx unknown
- 2002-04-17 DE DE60220516T patent/DE60220516T2/de not_active Expired - Lifetime
- 2002-04-17 AR ARP020101398A patent/AR034310A1/es unknown
- 2002-04-17 ES ES02717917T patent/ES2283541T3/es not_active Expired - Lifetime
- 2002-04-17 BR BR0208968-8A patent/BR0208968A/pt not_active IP Right Cessation
- 2002-04-17 MX MXPA03009446A patent/MXPA03009446A/es not_active Application Discontinuation
- 2002-04-17 PT PT02717917T patent/PT1381431E/pt unknown
- 2002-04-17 CZ CZ20033108A patent/CZ299735B6/cs not_active IP Right Cessation
- 2002-04-17 CA CA002444932A patent/CA2444932A1/en not_active Abandoned
- 2002-04-17 US US10/475,172 patent/US7846957B2/en not_active Expired - Fee Related
- 2002-04-17 AT AT02717917T patent/ATE363906T1/de active
- 2002-04-17 SK SK1425-2003A patent/SK14252003A3/sk unknown
-
2003
- 2003-09-23 NO NO20034245A patent/NO20034245L/no not_active Application Discontinuation
- 2003-09-26 ZA ZA200307514A patent/ZA200307514B/en unknown
- 2003-10-14 IL IL158395A patent/IL158395A/en not_active IP Right Cessation
- 2003-10-15 HR HR20030838A patent/HRP20030838A2/xx not_active Application Discontinuation
- 2003-11-05 BG BG108316A patent/BG108316A/bg unknown
-
2005
- 2005-02-15 HK HK05101178A patent/HK1067987A1/xx not_active IP Right Cessation
-
2007
- 2007-07-19 CY CY20071100965T patent/CY1108021T1/el unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal |