SI1381431T1 - Inhibicija aromataze za izboljĺ anje stopnje implantacije - Google Patents

Inhibicija aromataze za izboljĺ anje stopnje implantacije

Info

Publication number
SI1381431T1
SI1381431T1 SI200230565T SI200230565T SI1381431T1 SI 1381431 T1 SI1381431 T1 SI 1381431T1 SI 200230565 T SI200230565 T SI 200230565T SI 200230565 T SI200230565 T SI 200230565T SI 1381431 T1 SI1381431 T1 SI 1381431T1
Authority
SI
Slovenia
Prior art keywords
implantation rate
aromatase inhibition
enhance implantation
enhance
aromatase
Prior art date
Application number
SI200230565T
Other languages
English (en)
Inventor
Robert F Casper
Mohamed F M Mitwally
Original Assignee
Ares Trading Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ares Trading Sa filed Critical Ares Trading Sa
Publication of SI1381431T1 publication Critical patent/SI1381431T1/sl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4196—1,2,4-Triazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A61K31/5685—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone having an oxo group in position 17, e.g. androsterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/24—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g. HCG; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/32—Antioestrogens
SI200230565T 2001-04-17 2002-04-17 Inhibicija aromataze za izboljĺ anje stopnje implantacije SI1381431T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US28417801P 2001-04-17 2001-04-17
EP02717917A EP1381431B1 (en) 2001-04-17 2002-04-17 Aromatase inhibition to enhance implantation rate
PCT/CA2002/000522 WO2002083240A1 (en) 2001-04-17 2002-04-17 Aromatase inhibition to enhance assisted reproduction

Publications (1)

Publication Number Publication Date
SI1381431T1 true SI1381431T1 (sl) 2007-08-31

Family

ID=23089175

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200230565T SI1381431T1 (sl) 2001-04-17 2002-04-17 Inhibicija aromataze za izboljĺ anje stopnje implantacije

Country Status (33)

Country Link
US (1) US7846957B2 (sl)
EP (1) EP1381431B1 (sl)
JP (1) JP2004526764A (sl)
KR (1) KR20040012751A (sl)
CN (1) CN100377710C (sl)
AR (1) AR034310A1 (sl)
AT (1) ATE363906T1 (sl)
AU (1) AU2002249041B2 (sl)
BG (1) BG108316A (sl)
BR (1) BR0208968A (sl)
CA (1) CA2444932A1 (sl)
CY (1) CY1108021T1 (sl)
CZ (1) CZ299735B6 (sl)
DE (1) DE60220516T2 (sl)
DK (1) DK1381431T3 (sl)
EA (1) EA010354B1 (sl)
EE (1) EE200300512A (sl)
ES (1) ES2283541T3 (sl)
HK (1) HK1067987A1 (sl)
HR (1) HRP20030838A2 (sl)
HU (1) HUP0303795A2 (sl)
IL (2) IL158395A0 (sl)
MX (1) MXPA03009446A (sl)
NO (1) NO20034245L (sl)
NZ (1) NZ528501A (sl)
PL (1) PL366554A1 (sl)
PT (1) PT1381431E (sl)
SI (1) SI1381431T1 (sl)
SK (1) SK14252003A3 (sl)
UA (1) UA79591C2 (sl)
WO (1) WO2002083240A1 (sl)
YU (1) YU81303A (sl)
ZA (1) ZA200307514B (sl)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR0312393A (pt) * 2002-07-02 2005-04-12 Pharmacia & Upjohn Co Llc Tratamento de infertilidade com exemestano
CA2837494C (en) 2010-05-20 2019-12-31 University Of Saskatchewan Use of aromatase inhibitors for synchronizing ovulation, inducing superovulation or double ovulation and improving twinning and fertility in a mammal
WO2012127501A2 (en) * 2011-03-11 2012-09-27 Sanzyme Limited Composition for improving endometrial thickness during ovarian stimulation
SG2014012132A (en) 2011-09-08 2014-06-27 Novartis Ag Use of an aromatase inhibitor for the treatment of hypogonadism and related diseases
US10004723B2 (en) 2013-04-19 2018-06-26 University Of Saskatchewan Aromatase inhibitor-releasing intravaginal device
CN107648594A (zh) * 2017-11-08 2018-02-02 广州市桐晖药业有限公司 枸橼酸氯米芬胶囊及其制备方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4289762A (en) * 1980-06-27 1981-09-15 Merrell Dow Pharmaceuticals Inc. 10-(1,2-Propadienyl) steroids as irreversible aromatase inhibitors
US4728645A (en) * 1982-12-21 1988-03-01 Ciba-Geigy Corporation Substituted imidazo[1,5-A]pyridine derivatives and other substituted bicyclic derivatives, useful as aromatase inhibitors
US4845227A (en) * 1984-06-18 1989-07-04 Eli Lilly And Company Aromatase inhibitors from azoles
US4978672A (en) * 1986-03-07 1990-12-18 Ciba-Geigy Corporation Alpha-heterocyclc substituted tolunitriles
DE4330237C2 (de) * 1993-09-02 1995-11-30 Schering Ag 1-Methylsubstituierte Androsta-1,4-dien-3,17-dione, Verfahren zu deren Herstellung und diese enthaltende pharmazeutische Präparate
AU1793397A (en) 1996-03-29 1997-10-22 S.W. Patentverwertungs Ges. M.B.H. Edelsbacher U. Partner Cosmetic or cosmetic preparation for smoothing and tightening the skin in the case of subcutaneous fatty tissue problems, particularly cellulite
US6015789A (en) * 1996-04-30 2000-01-18 Takeda Chemical Industries, Ltd. Combined use of GnRH agonist and antagonist
DE19622457A1 (de) 1996-05-24 1997-11-27 Schering Ag 7alpha-(5-Methylaminopentyl)-estratriene, Verfahren zu deren Herstellung, pharmazeutische Präparate, die diese 7alpha-(5-Methylaminopentyl)-estratriene enthalten sowie deren Verwendung zur Herstellung von Arzneimitteln
ATE302018T1 (de) * 1997-06-20 2005-09-15 Akzo Nobel Nv Gonadotropin releasing hormon antagonist
US6953774B2 (en) * 2000-08-11 2005-10-11 Applied Research Systems Ars Holding N.V. Methods of inducing ovulation

Also Published As

Publication number Publication date
UA79591C2 (en) 2007-07-10
AR034310A1 (es) 2004-02-18
EP1381431B1 (en) 2007-06-06
NO20034245D0 (no) 2003-09-23
HRP20030838A2 (en) 2005-08-31
PL366554A1 (en) 2005-02-07
EA010354B1 (ru) 2008-08-29
BR0208968A (pt) 2004-04-27
HK1067987A1 (en) 2005-04-22
ZA200307514B (en) 2004-09-27
ES2283541T3 (es) 2007-11-01
MXPA03009446A (es) 2004-05-24
WO2002083240A9 (en) 2004-05-06
CN1549734A (zh) 2004-11-24
JP2004526764A (ja) 2004-09-02
WO2002083240A1 (en) 2002-10-24
ATE363906T1 (de) 2007-06-15
CY1108021T1 (el) 2013-09-04
IL158395A0 (en) 2004-05-12
YU81303A (sh) 2006-05-25
CN100377710C (zh) 2008-04-02
EP1381431A1 (en) 2004-01-21
HUP0303795A2 (hu) 2004-03-29
EA200301129A1 (ru) 2004-04-29
BG108316A (bg) 2004-12-30
DE60220516T2 (de) 2007-10-11
EE200300512A (et) 2004-02-16
NZ528501A (en) 2008-04-30
US20040204393A1 (en) 2004-10-14
CZ299735B6 (cs) 2008-11-05
AU2002249041B2 (en) 2007-07-12
NO20034245L (no) 2003-12-15
SK14252003A3 (sk) 2004-03-02
IL158395A (en) 2009-06-15
DE60220516D1 (de) 2007-07-19
KR20040012751A (ko) 2004-02-11
DK1381431T3 (da) 2007-10-08
CA2444932A1 (en) 2002-10-24
US7846957B2 (en) 2010-12-07
CZ20033108A3 (en) 2004-06-16
PT1381431E (pt) 2007-07-03

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