DK1373480T3 - Ukoblede produktive og katabolske værtscellebaner - Google Patents

Ukoblede produktive og katabolske værtscellebaner

Info

Publication number
DK1373480T3
DK1373480T3 DK02763934T DK02763934T DK1373480T3 DK 1373480 T3 DK1373480 T3 DK 1373480T3 DK 02763934 T DK02763934 T DK 02763934T DK 02763934 T DK02763934 T DK 02763934T DK 1373480 T3 DK1373480 T3 DK 1373480T3
Authority
DK
Denmark
Prior art keywords
host cells
catabolic
nucleic acid
host cell
cell pathways
Prior art date
Application number
DK02763934T
Other languages
English (en)
Inventor
Fernando Valle
Timothy C Dodge
Original Assignee
Genencor Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genencor Int filed Critical Genencor Int
Application granted granted Critical
Publication of DK1373480T3 publication Critical patent/DK1373480T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/02—Monosaccharides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P25/00—Preparation of compounds containing alloxazine or isoalloxazine nucleus, e.g. riboflavin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/58—Aldonic, ketoaldonic or saccharic acids
    • C12P7/60—2-Ketogulonic acid

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK02763934T 2001-04-04 2002-04-04 Ukoblede produktive og katabolske værtscellebaner DK1373480T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US28161801P 2001-04-04 2001-04-04
US28225901P 2001-04-05 2001-04-05
PCT/US2002/010575 WO2002081631A2 (en) 2001-04-04 2002-04-04 Uncoupled productive and catabolic host cell pathways

Publications (1)

Publication Number Publication Date
DK1373480T3 true DK1373480T3 (da) 2009-05-11

Family

ID=26960977

Family Applications (1)

Application Number Title Priority Date Filing Date
DK02763934T DK1373480T3 (da) 2001-04-04 2002-04-04 Ukoblede produktive og katabolske værtscellebaner

Country Status (9)

Country Link
US (2) US7241587B2 (da)
EP (2) EP1373480B1 (da)
JP (2) JP4430869B2 (da)
AT (2) ATE421577T1 (da)
AU (1) AU2002338340A1 (da)
CA (1) CA2443145C (da)
DE (1) DE60230971D1 (da)
DK (1) DK1373480T3 (da)
WO (1) WO2002081631A2 (da)

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DE60229050D1 (de) * 2001-04-04 2008-11-06 Genencor Int Verfahren zur herstellung von ascorbinsäurezwischenprodukten in wirtszellen
RU2006125498A (ru) * 2003-12-18 2008-01-27 БАСФ Акциенгезельшафт (DE) Способы получения химического продукта тонкого органического синтеза путем ферментации
CN101292026B (zh) * 2005-09-09 2013-04-24 帝斯曼知识产权资产管理有限公司 新颖的基因gms 08
US8222223B2 (en) * 2005-09-20 2012-07-17 Battelle Memorial Institute Method of treating biocells
US7790427B1 (en) * 2005-09-20 2010-09-07 Battelle Memorial Institute Method of treating biocells
AT505263B1 (de) * 2007-06-01 2009-08-15 Vogelbusch Gmbh Verfahren zum herstellen von ascorbinsäure
DK2235190T3 (da) 2007-12-13 2018-07-23 Danisco Us Inc Sammensætninger og fremgangsmåder til fremstilling af isopren
EP2279251A2 (en) 2008-04-23 2011-02-02 Danisco US Inc. Isoprene synthase variants for improved microbial production of isoprene
CA2729302A1 (en) 2008-06-30 2010-01-14 The Goodyear Tire & Rubber Company Polymers of isoprene from renewable resources
EP3406722A1 (en) * 2008-07-02 2018-11-28 Danisco US Inc. Methods for producing isoprene free of c5 hydrocarbons under decoupling conditions and/or safe operating ranges
US8476049B2 (en) * 2008-09-15 2013-07-02 Danisco Us Inc. Conversion of prenyl derivatives to isoprene
SG169641A1 (en) 2008-09-15 2011-04-29 Danisco Us Inc Systems using cell culture for production of isoprene
CA2737223A1 (en) * 2008-09-15 2010-03-18 Danisco Us Inc. Reduction of carbon dioxide emission during isoprene production by fermentation
MY169163A (en) 2008-09-15 2019-02-19 Danisco Us Inc Increased isoprene production using the archaeal lower mevalonate pathway
CA2737082A1 (en) * 2008-09-15 2010-03-18 Danisco Us Inc. Increased isoprene production using mevalonate kinase and isoprene synthase
JP5793424B2 (ja) 2008-12-30 2015-10-14 ダニスコ・ユーエス・インク イソプレンと副生成物の産出方法
WO2010092924A1 (ja) * 2009-02-10 2010-08-19 国立大学法人宮崎大学 ペントース資化性エタノール生産組換え大腸菌及びこれを用いるエタノールの製造方法
CA2759700A1 (en) * 2009-04-23 2010-10-28 Danisco Us Inc. Three-dimensional structure of isoprene synthase and its use thereof for generating variants
TWI427149B (zh) * 2009-06-17 2014-02-21 Danisco Us Inc 使用ｄｘｐ及ｍｖａ途徑之改良之異戊二烯製造
TWI434921B (zh) * 2009-06-17 2014-04-21 Danisco Us Inc 從生物異戊二烯組合物製造燃料成分之方法及系統
CN103025688A (zh) 2010-06-17 2013-04-03 丹尼斯科美国公司 包含异戊二烯衍生物的燃料组合物
NZ605093A (en) 2010-07-12 2014-05-30 Univ Gent Metabolically engineered organisms for the production of added value bio-products
JP2014502148A (ja) 2010-10-27 2014-01-30 ダニスコ・ユーエス・インク イソプレン生産の向上を目的としたイソプレン合成酵素変異体
US8288137B2 (en) * 2010-11-15 2012-10-16 E I Du Pont De Nemours And Company Recombinant Escherichia coli having enhanced acetyl-coenzyme a synthetase activity for producing glyerol and glycerol-derived products
CN103403145A (zh) 2010-12-22 2013-11-20 丹尼斯科美国公司 使用重组细胞进行戊糖的生物制备
EP2655606A1 (en) 2010-12-22 2013-10-30 Danisco US Inc. Compositions and methods for improved isoprene production using two types of ispg enzymes
US9163263B2 (en) 2012-05-02 2015-10-20 The Goodyear Tire & Rubber Company Identification of isoprene synthase variants with improved properties for the production of isoprene

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Also Published As

Publication number Publication date
EP2055773B1 (en) 2011-06-15
CA2443145A1 (en) 2002-10-17
DE60230971D1 (de) 2009-03-12
JP5328038B2 (ja) 2013-10-30
JP2005503769A (ja) 2005-02-10
ATE513036T1 (de) 2011-07-15
WO2002081631A3 (en) 2002-11-28
EP1373480A4 (en) 2005-02-02
US7241587B2 (en) 2007-07-10
US20070059811A1 (en) 2007-03-15
US20030073200A1 (en) 2003-04-17
JP4430869B2 (ja) 2010-03-10
EP2055773A1 (en) 2009-05-06
JP2010057499A (ja) 2010-03-18
CA2443145C (en) 2013-01-22
WO2002081631A2 (en) 2002-10-17
US7407780B2 (en) 2008-08-05
AU2002338340A1 (en) 2002-10-21
EP1373480A2 (en) 2004-01-02
ATE421577T1 (de) 2009-02-15
EP1373480B1 (en) 2009-01-21

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