DK137188B - ANALOGICAL PROCEDURE FOR THE PREPARATION OF 2-TETRAHYDROFURYL-6,7-BENZOMORPHANES OR ACID ADDITIONAL SALTS THEREOF - Google Patents

ANALOGICAL PROCEDURE FOR THE PREPARATION OF 2-TETRAHYDROFURYL-6,7-BENZOMORPHANES OR ACID ADDITIONAL SALTS THEREOF

Info

Publication number
DK137188B
DK137188B DK92975AA DK92975A DK137188B DK 137188 B DK137188 B DK 137188B DK 92975A A DK92975A A DK 92975AA DK 92975 A DK92975 A DK 92975A DK 137188 B DK137188 B DK 137188B
Authority
DK
Denmark
Prior art keywords
benzomorphanes
tetrahydrofuryl
preparation
additional salts
acid additional
Prior art date
Application number
DK92975AA
Other languages
Danish (da)
Other versions
DK137188C (en
DK92975A (en
Inventor
H Merz
A Langbein
G Walther
K Stockhaus
Original Assignee
Boehringer Sohn Ingelheim
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Sohn Ingelheim filed Critical Boehringer Sohn Ingelheim
Publication of DK92975A publication Critical patent/DK92975A/da
Publication of DK137188B publication Critical patent/DK137188B/en
Application granted granted Critical
Publication of DK137188C publication Critical patent/DK137188C/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/22—Bridged ring systems
    • C07D221/26—Benzomorphans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK92975A 1974-03-09 1975-03-07 ANALOGICAL PROCEDURE FOR THE PREPARATION OF 2-TETRAHYDROFURFURYL-6,7-BENZOMORPHANES OR ACID ADDITIONAL SALTS THEREOF DK137188C (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2411382A DE2411382C3 (en) 1974-03-09 1974-03-09 2-Tetrahydrofurfuryl-6,7-benzomorphane, process for the preparation and their use

Publications (3)

Publication Number Publication Date
DK92975A DK92975A (en) 1975-09-10
DK137188B true DK137188B (en) 1978-01-30
DK137188C DK137188C (en) 1978-07-03

Family

ID=5909593

Family Applications (1)

Application Number Title Priority Date Filing Date
DK92975A DK137188C (en) 1974-03-09 1975-03-07 ANALOGICAL PROCEDURE FOR THE PREPARATION OF 2-TETRAHYDROFURFURYL-6,7-BENZOMORPHANES OR ACID ADDITIONAL SALTS THEREOF

Country Status (25)

Country Link
JP (1) JPS5827275B2 (en)
AT (1) AT344332B (en)
BE (1) BE826440A (en)
BG (3) BG24813A4 (en)
CA (1) CA1049511A (en)
CH (8) CH612425A5 (en)
CS (1) CS188221B2 (en)
DD (1) DD119236A5 (en)
DE (1) DE2411382C3 (en)
DK (1) DK137188C (en)
ES (6) ES440350A1 (en)
FI (1) FI63571C (en)
FR (1) FR2262984B1 (en)
GB (1) GB1496418A (en)
HU (1) HU177408B (en)
IE (1) IE40945B1 (en)
IL (1) IL46760A (en)
NL (1) NL7502724A (en)
NO (1) NO141800C (en)
PH (1) PH14127A (en)
PL (3) PL93700B1 (en)
RO (2) RO69617A (en)
SE (1) SE421919B (en)
SU (3) SU577982A3 (en)
ZA (1) ZA751394B (en)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2716687A1 (en) * 1977-04-15 1978-10-19 Boehringer Sohn Ingelheim 2'-HYDROXY-2- (5-ISOXAZOLYLMETHYL) -6.7BENZOMORPHANES, THEIR ACID ADDITIONAL SALTS AND MEDICINAL PRODUCTS CONTAINING THEM
DE2828039A1 (en) * 1978-06-26 1980-01-10 Boehringer Sohn Ingelheim 2- (2-ALKOXYETHYL) -2'-HYDROXY-6,7-BENZOMORPHANES THEIR ACID ADDITION SALTS, THESE MEDICINAL PRODUCTS, AND METHOD FOR THE PRODUCTION THEREOF
US6992107B1 (en) 1995-03-10 2006-01-31 Photocure Asa Esters of 5-aminolevulinic acid and their use as photosensitizing compounds in photochemotherapy
US6492420B2 (en) 1995-03-10 2002-12-10 Photocure As Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy
CZ291132B6 (en) * 1995-03-10 2002-12-11 Photocure Asa Esters of 5-aminolevullinic acids and pharmaceutical preparation in which the esters are comprised
US7530461B2 (en) 1995-03-10 2009-05-12 Photocure Asa Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy
GB0018528D0 (en) 2000-07-27 2000-09-13 Photocure Asa Compounds
US6723750B2 (en) 2002-03-15 2004-04-20 Allergan, Inc. Photodynamic therapy for pre-melanomas
ATE554078T1 (en) 2007-07-26 2012-05-15 Vitae Pharmaceuticals Inc SYNTHESIS OF 11-BETA-HYDROXYSTEROID DEHYDROGENASE-1 INHIBITORS
WO2009063061A2 (en) 2007-11-16 2009-05-22 Boehringer Ingelheim International Gmbh Aryl- and heteroarylcarbonyl derivatives of benzomorphanes and related scaffolds, medicaments containing such compounds and their use
JP5490014B2 (en) 2007-12-11 2014-05-14 ヴァイティー ファーマシューティカルズ，インコーポレイテッド 11β-hydroxysteroid dehydrogenase type 1 cyclic urea inhibitor
TW200934490A (en) 2008-01-07 2009-08-16 Vitae Pharmaceuticals Inc Lactam inhibitors of 11 &abgr;-hydroxysteroid dehydrogenase 1
JP5490020B2 (en) 2008-01-24 2014-05-14 ヴァイティー ファーマシューティカルズ，インコーポレイテッド Cyclic carbazate and semicarbazide inhibitors of 11β-hydroxysteroid dehydrogenase 1
EP2254872A2 (en) 2008-02-15 2010-12-01 Vitae Pharmaceuticals, Inc. Cycloalkyl lactame derivatives as inhibitors of 11-beta-hydroxysteroid dehydrogenase 1
EP2300461B1 (en) 2008-05-01 2013-04-17 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
JP5538365B2 (en) 2008-05-01 2014-07-02 ヴァイティー ファーマシューティカルズ，インコーポレイテッド Cyclic inhibitor of 11β-hydroxysteroid dehydrogenase 1
TW201004945A (en) 2008-05-01 2010-02-01 Vitae Pharmaceuticals Inc Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
CA2724214A1 (en) 2008-05-13 2009-11-19 Boehringer Ingelheim International Gmbh Alicyclic carboxylic acid derivatives of benzomorphans and related scaffolds, medicaments containing such compounds and their use
US8846668B2 (en) 2008-07-25 2014-09-30 Vitae Pharmaceuticals, Inc. Inhibitors of 11beta-hydroxysteroid dehydrogenase 1
DK2324018T3 (en) 2008-07-25 2013-10-14 Boehringer Ingelheim Int CYCLE INHIBITORS OF 11 BETA-HYDROXYSTEROID DEHYDROGENASE 1
UA109255C2 (en) 2009-04-30 2015-08-10 Берінгер Інгельхайм Інтернешнл Гмбх Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
EP2440537A1 (en) 2009-06-11 2012-04-18 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 based on the 1,3 -oxazinan- 2 -one structure
TWI531571B (en) 2009-11-06 2016-05-01 維它藥物公司 Aryl-and heteroarylcarbonyl derivatives of hexahydroindenopyridine and octahydrobenzoquinoline
US8933072B2 (en) 2010-06-16 2015-01-13 Vitae Pharmaceuticals, Inc. Substituted 5-,6- and 7-membered heterocycles, medicaments containing such compounds, and their use
TWI537258B (en) 2010-11-05 2016-06-11 百靈佳殷格翰國際股份有限公司 Aryl-and heteroarylcarbonyl derivatives of hexahydroindenopyridine and octahydrobenzoquinoline
US8735585B2 (en) 2011-08-17 2014-05-27 Boehringer Ingelheim International Gmbh Indenopyridine derivatives

Also Published As

Publication number Publication date
DD119236A5 (en) 1976-04-12
NO141800C (en) 1980-06-04
CH622016A5 (en) 1981-03-13
CH612425A5 (en) 1979-07-31
IL46760A0 (en) 1975-05-22
DE2411382C3 (en) 1979-09-06
ES440348A1 (en) 1977-06-01
ES440347A1 (en) 1977-06-01
ATA153875A (en) 1977-11-15
AT344332B (en) 1978-07-10
NO750773L (en) 1975-09-10
IL46760A (en) 1978-12-17
DK137188C (en) 1978-07-03
CS188221B2 (en) 1979-02-28
JPS50123675A (en) 1975-09-29
CH620440A5 (en) 1980-11-28
AU7894275A (en) 1976-09-16
DE2411382B2 (en) 1979-01-18
CH622014A5 (en) 1981-03-13
SU588916A3 (en) 1978-01-15
ZA751394B (en) 1976-11-24
SU577983A3 (en) 1977-10-25
DE2411382A1 (en) 1975-09-18
RO70051A (en) 1980-12-30
SU577982A3 (en) 1977-10-25
ES440345A1 (en) 1977-03-01
PL93499B1 (en) 1977-05-30
GB1496418A (en) 1977-12-30
PH14127A (en) 1981-02-26
CH620681A5 (en) 1980-12-15
BG24814A4 (en) 1978-05-12
CH622017A5 (en) 1981-03-13
FR2262984B1 (en) 1978-07-28
DK92975A (en) 1975-09-10
RO69617A (en) 1980-08-15
SE421919B (en) 1982-02-08
CH620439A5 (en) 1980-11-28
IE40945B1 (en) 1979-09-12
NO141800B (en) 1980-02-04
BE826440A (en) 1975-09-08
BG25087A3 (en) 1978-07-12
ES440350A1 (en) 1977-03-16
JPS5827275B2 (en) 1983-06-08
FR2262984A1 (en) 1975-10-03
FI63571C (en) 1983-07-11
IE40945L (en) 1975-09-09
ES440349A1 (en) 1977-03-01
FI750652A (en) 1975-09-10
BG24813A4 (en) 1978-05-12
CA1049511A (en) 1979-02-27
ES440346A1 (en) 1977-03-01
NL7502724A (en) 1975-09-11
PL93700B1 (en) 1977-06-30
HU177408B (en) 1981-10-28
SE7502592L (en) 1975-09-10
FI63571B (en) 1983-03-31
PL93699B1 (en) 1977-06-30
CH622015A5 (en) 1981-03-13

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