DK135775B - Analogifremgangsmåde til fremstilling af mættede 3alfa-hydroxy-5alfa-pregnaner. - Google Patents

Analogifremgangsmåde til fremstilling af mættede 3alfa-hydroxy-5alfa-pregnaner.

Info

Publication number
DK135775B
DK135775B DK260473AA DK260473A DK135775B DK 135775 B DK135775 B DK 135775B DK 260473A A DK260473A A DK 260473AA DK 260473 A DK260473 A DK 260473A DK 135775 B DK135775 B DK 135775B
Authority
DK
Denmark
Prior art keywords
pregnanes
3alpha
5alpha
hydroxy
saturated
Prior art date
Application number
DK260473AA
Other languages
Danish (da)
English (en)
Other versions
DK135775C (ja
Inventor
Gordon Hanley Phillipps
Robin Lawrence
Leslie Stephenson
Barry Edward Ayres
Original Assignee
Glazo Lab Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glazo Lab Ltd filed Critical Glazo Lab Ltd
Publication of DK135775B publication Critical patent/DK135775B/da
Application granted granted Critical
Publication of DK135775C publication Critical patent/DK135775C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK260473AA 1972-05-12 1973-05-11 Analogifremgangsmåde til fremstilling af mættede 3alfa-hydroxy-5alfa-pregnaner. DK135775B (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB2248972A GB1436324A (en) 1972-05-12 1972-05-12 Anaesthetic 3alpha-hydroxy pregnanes

Publications (2)

Publication Number Publication Date
DK135775B true DK135775B (da) 1977-06-20
DK135775C DK135775C (ja) 1977-11-21

Family

ID=10180241

Family Applications (1)

Application Number Title Priority Date Filing Date
DK260473AA DK135775B (da) 1972-05-12 1973-05-11 Analogifremgangsmåde til fremstilling af mættede 3alfa-hydroxy-5alfa-pregnaner.

Country Status (13)

Country Link
US (1) US3998829A (ja)
JP (1) JPS4948652A (ja)
AU (1) AU474687B2 (ja)
BE (1) BE799433A (ja)
CA (1) CA1014947A (ja)
DE (1) DE2323950A1 (ja)
DK (1) DK135775B (ja)
FR (1) FR2184711B1 (ja)
GB (1) GB1436324A (ja)
IE (1) IE38863B1 (ja)
LU (1) LU67585A1 (ja)
NL (1) NL7306606A (ja)
ZA (1) ZA733218B (ja)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4613463A (en) * 1984-11-01 1986-09-23 The Upjohn Company Process and intermediates for the preparation of 17 alphahydroxyprogesterones and corticoids from an enol steroid
US5099019A (en) * 1985-09-12 1992-03-24 Upjohn Company Amines useful in producing pharmaceutically active CNS compounds
USRE35053E (en) * 1985-09-12 1995-10-10 The Upjohn Company Amines useful in producing pharmaceutically active CNS compounds
US5380839A (en) * 1985-09-12 1995-01-10 The Upjohn Company Phenylpiperazinyl steroids
US5232917A (en) * 1987-08-25 1993-08-03 University Of Southern California Methods, compositions, and compounds for allosteric modulation of the GABA receptor by members of the androstane and pregnane series
JPH072555Y2 (ja) * 1991-06-03 1995-01-25 日野自動車工業株式会社 車輛の前後方向兼用ウインチ
CZ394197A3 (cs) * 1995-06-06 1998-06-17 Cocensys, Inc. Neuroaktivní steroidy androstanové a pregnanové řady
US6780853B1 (en) 1995-06-06 2004-08-24 Euro-Celtique S.A. Neuroactive steroids of the androstane and pregnane series
US6143737A (en) * 1995-06-23 2000-11-07 Georgetown University Progesterone analogs to reverse multidrug resistance
WO2000066614A1 (en) * 1999-04-29 2000-11-09 Purdue Pharma Ltd. 3α-HYDROXY-3β METHOXYMETHYL-21-HETEROCYCLE SUBSTITUTED STEROIDS WITH ANESTHETIC ACTIVITY
US20050101581A1 (en) * 2002-08-28 2005-05-12 Reading Christopher L. Therapeutic treatment methods 2
CN108976272B (zh) 2011-10-14 2021-05-25 萨奇治疗股份有限公司 3,3-二取代的19-去甲孕甾烷化合物、组合物、及其用途
US20160068563A1 (en) 2013-04-17 2016-03-10 Boyd L. Harrison 19-nor neuroactive steroids and methods of use thereof
ES2807264T3 (es) 2013-04-17 2021-02-22 Sage Therapeutics Inc Esteroides neuroactivos 19-nor para métodos de tratamiento
HUE041369T2 (hu) 2013-04-17 2019-05-28 Sage Therapeutics Inc 19-nor C3,3-diszubsztituált C21-N-pirazolil-szteroidok és eljárás ezek alkalmazására
US9725481B2 (en) 2013-04-17 2017-08-08 Sage Therapeutics, Inc. 19-nor C3, 3-disubstituted C21-C-bound heteroaryl steroids and methods of use thereof
CA3199003A1 (en) 2013-07-19 2015-01-22 Sage Therapeutics, Inc. Neuroactive steroids, compositions, and uses thereof
CA3235088A1 (en) 2013-08-23 2015-02-26 Sage Therapeutics, Inc. Neuroactive steroids, compositions, and uses thereof
WO2015195962A1 (en) 2014-06-18 2015-12-23 Sage Therapeutics, Inc. Neuroactive steroids, compositions, and uses thereof
MX2017005002A (es) 2014-10-16 2018-01-23 Sage Therapeutics Inc Composiciones y metodos para el tratamiento de trastornos del snc.
US20170233433A1 (en) 2014-10-16 2017-08-17 Sage Therapeutics, Inc. Compositions and methods for treating cns disorders
EP3719029A1 (en) 2014-11-27 2020-10-07 Sage Therapeutics, Inc. Compositions for inducing sedation
RS61530B1 (sr) 2015-01-26 2021-04-29 Sage Therapeutics Inc Kompozicije i postupci za lečenje poremećaja cns
DK3258939T3 (da) 2015-02-20 2022-12-12 Sage Therapeutics Inc Neuroaktive steroider, sammensætninger og anvendelser heraf
IL309259A (en) 2016-07-11 2024-02-01 Sage Therapeutics Inc C17, C20 and C21 converted neuroactive steroids and methods of using them
JP7065825B2 (ja) 2016-07-11 2022-05-12 セージ セラピューティクス， インコーポレイテッド Ｃ７、ｃ１２、およびｃ１６置換神経刺激性ステロイドおよびそれらの使用方法
MA56046A (fr) 2019-05-31 2022-04-06 Sage Therapeutics Inc Stéroïdes neuroactifs et compositions associées

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1107662B (de) * 1959-07-04 1961-05-31 Merck Ag E Verfahren zur Herstellung von Mannichbasen von Steroiden bzw. von deren Saeureadditionssalzen
US3042691A (en) * 1960-05-11 1962-07-03 Pfizer & Co C 5alpha,21-dibromo-6beta-fluoro-21-methyl-pregnanes and process for making same
FR1764M (fr) * 1962-02-20 1963-04-08 Roussel Uclaf Nouveau médicament notamment pour le traitement des spasmes d'origine coronarienne ou viscérale.
US3201425A (en) * 1963-12-10 1965-08-17 American Cyanamid Co 20-alkoxy-delta20-21-carboxaldehydes of the pregnane series and method of preparing the same
GB1089945A (en) * 1965-09-23 1967-11-08 British Drug Houses Ltd Steroidal-6-spirocyclopropyl-4-en-3-ones
GB1317184A (en) * 1969-06-20 1973-05-16 Glaxo Lab Ltd Steroid-containing pharmaceutical preparations
DE1941226A1 (de) * 1969-08-13 1971-02-18 Degussa Basisch substituierte Ketosteroide
US3661940A (en) * 1970-04-13 1972-05-09 Sandoz Ag Derivatives of 21-methyl-19-norpregnanes
GB1377609A (en) * 1970-12-17 1974-12-18 Glaxo Lab Ltd 3alpha-hydroxy-5alpha-pregnane compounds
GB1416427A (en) * 1972-01-12 1975-12-03 Akzo Nv Alkylated pregnanes and process for obtaining same

Also Published As

Publication number Publication date
FR2184711A1 (ja) 1973-12-28
IE38863L (en) 1973-11-12
BE799433A (fr) 1973-11-12
AU5561673A (en) 1974-11-14
IE38863B1 (en) 1978-06-21
JPS4948652A (ja) 1974-05-11
CA1014947A (en) 1977-08-02
GB1436324A (en) 1976-05-19
LU67585A1 (ja) 1973-07-24
DE2323950A1 (de) 1973-12-13
NL7306606A (ja) 1973-11-14
FR2184711B1 (ja) 1977-01-07
DK135775C (ja) 1977-11-21
AU474687B2 (en) 1976-07-29
ZA733218B (en) 1974-05-29
US3998829A (en) 1976-12-21

Similar Documents

Publication Publication Date Title
DK134607B (da) Fremgangsmåde til fremstilling af rapamycin.
DK138951B (da) Fremgangsmåde til fremstilling af N-phosphonomethyl-glycin.
DK137329B (da) Analogifremgangsmåde til fremstilling af 2-karbalkoksyaminobenzimidazolderivater.
DK135775B (da) Analogifremgangsmåde til fremstilling af mættede 3alfa-hydroxy-5alfa-pregnaner.
DK131868B (da) Analogifremgangsmåde til fremstilling af tri-p-toluensulfonatet af S-adenosyl-L-methionin.
DK132500B (da) Analogifremgangsmåde til fremstilling af 2beta, 16beta-diamino-5alfa-androstaner.
DK134604B (da) Fremgangsmåde til fremstilling af indenyl-3-acetoglucuronider.
DK138796B (da) Analogifremgangsmåde til fremstilling af 2-carboxypyrazin-4-oxidderivater.
DK137639B (da) Analogifremgangsmåde til fremstilling af 1-aminomethyl-2,2-diaryl-cyclopropancarboxamider.
DK129088B (da) Fremgangsmåde til fremstilling af peptider.
DK138230B (da) Analogifremgangsmåde til fremstilling af vincanolsalte.
DK138898B (da) Fremgangsmåde til fremstilling af N-phosphonomethylglycin.
DK140668B (da) Analogifremgangsmåde til fremstilling af kondenserede pyriminderivater.
DK131942B (da) Fremgangsmåde til fremstilling af delta4,16-11beta-hydroxy-3,20-diketopregnadiener.
DK131864B (da) Fremgangsmåde til fremstilling af pregnan-21-syrederivater.
DK132233B (da) Fremgangsmåde til fremstilling af antibiotikum A-2315.
DK131575B (da) Analogifremgangsmåde til fremstilling af 2beta-hydroxy-3alfa-aminosteroider.
DK138645B (da) Analogifremgangsmåde til fremstilling af sulfamoylfenyl-imidazolidiner.
DK135122B (da) Analogifremgangsmåde til fremstilling af 4-aryl-5-aminoalkyl-4-oxazolin-2-onderivater.
DK129657B (da) Analogifremgangsmåde til fremstilling af 3-methylpyrazol-5-carboxamider.
DK135166B (da) Analogifremgangsmåde til fremstilling af 2-methyl-5-nitro-imidazoler.
DK131855B (da) Fremgangsmåde til fremstilling af 3,4-dihydropyridoner.
DK134183B (da) Fremgangsmåde til fremstilling af cellulose-enzymkomplekser.
DK139677B (da) Fremgangsmåde til fremstilling af 7-benzoylindolin-2-oner.
DK132410B (da) Analogifremgangsmåde til fremstilling af 2-amino-4H-pyraner.