DK135685D0 - L-n-n-propylpipecolinsyre-2,6-xylidid og fremgangsmaade til fremstilling deraf - Google Patents

L-n-n-propylpipecolinsyre-2,6-xylidid og fremgangsmaade til fremstilling deraf

Info

Publication number
DK135685D0
DK135685D0 DK135685A DK135685A DK135685D0 DK 135685 D0 DK135685 D0 DK 135685D0 DK 135685 A DK135685 A DK 135685A DK 135685 A DK135685 A DK 135685A DK 135685 D0 DK135685 D0 DK 135685D0
Authority
DK
Denmark
Prior art keywords
acid
xylidide
propylpipecolic
yield
xylideide
Prior art date
Application number
DK135685A
Other languages
English (en)
Other versions
DK135685A (da
DK153546B (da
DK153546C (da
Inventor
Af Ekenstam Bo Thuresson
Christer Bovin
Original Assignee
Apothekernes Lab
Af Ekenstam Bo Thuresson
Christer Bovin
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Apothekernes Lab, Af Ekenstam Bo Thuresson, Christer Bovin filed Critical Apothekernes Lab
Publication of DK135685A publication Critical patent/DK135685A/da
Publication of DK135685D0 publication Critical patent/DK135685D0/da
Publication of DK153546B publication Critical patent/DK153546B/da
Application granted granted Critical
Publication of DK153546C publication Critical patent/DK153546C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
DK135685A 1983-08-01 1985-03-26 Analogifremgangsmaade til fremstilling af l-n-n-propylpipecolinsyre-2,6-xylidid eller et farmaceutisk acceptabelt, vandoploeseligt salt deraf DK153546C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/NO1983/000029 WO1985000599A1 (en) 1983-08-01 1983-08-01 L-N-n-PROPYLPIPECOLIC ACID-2,6-XYLIDIDE AND METHOD FOR PREPARING THE SAME
NO8300029 1983-08-01

Publications (4)

Publication Number Publication Date
DK135685A DK135685A (da) 1985-03-26
DK135685D0 true DK135685D0 (da) 1985-03-26
DK153546B DK153546B (da) 1988-07-25
DK153546C DK153546C (da) 1988-12-05

Family

ID=19907251

Family Applications (1)

Application Number Title Priority Date Filing Date
DK135685A DK153546C (da) 1983-08-01 1985-03-26 Analogifremgangsmaade til fremstilling af l-n-n-propylpipecolinsyre-2,6-xylidid eller et farmaceutisk acceptabelt, vandoploeseligt salt deraf

Country Status (12)

Country Link
EP (1) EP0151110B1 (da)
JP (1) JPS60502054A (da)
AT (1) ATE40994T1 (da)
AU (1) AU560367B2 (da)
CY (1) CY1623A (da)
DE (1) DE3379266D1 (da)
DK (1) DK153546C (da)
FI (1) FI80020C (da)
HK (1) HK98391A (da)
MY (1) MY101904A (da)
SG (1) SG87991G (da)
WO (1) WO1985000599A1 (da)

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PT86249B (pt) * 1987-02-06 1991-02-08 Fisons Corp Processo de preparacao de derivados de azaciclocarboxamida
SE9000288D0 (sv) * 1990-01-26 1990-01-26 Astra Ab New use
FR2702220B1 (fr) * 1993-03-03 1995-05-12 Synthelabo Dédoublement enzymatique de dérivés de 4-alkyl-2-pipéridine-carboxylate et utilisation des composés obtenus, comme intermédiaires de synthèse.
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US7799337B2 (en) 1997-07-21 2010-09-21 Levin Bruce H Method for directed intranasal administration of a composition
SE9800139D0 (sv) * 1998-01-21 1998-01-21 Astra Ab New use
EP1433782A4 (en) 2001-09-10 2005-04-27 Mercian Corp PROCESS FOR PRODUCING A PIPECOLAMIDE DERIVATIVE
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ITMI20051144A1 (it) * 2005-06-17 2006-12-18 Molteni & C Dei Fratellei Alit "procedimento per la preparazione d'una soluzione iniettabile di (2s)-n-(2;6-dimetil-fenil)-1-propil-2-piperidincarbossiamide"
WO2007123405A1 (en) * 2006-04-25 2007-11-01 Dishman Pharmaceuticals And Chemicals Ltd. Ropivacaine hydrochloride anhydrate and the preparation thereof
KR20140097446A (ko) 2006-11-20 2014-08-06 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 통증 및 소양증 치료용 방법, 조성물 및 키트
KR100844336B1 (ko) * 2007-01-16 2008-07-07 하나제약 주식회사 레보부피바카인 및 이의 염산염의 신규한 제조방법
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WO2009044404A1 (en) * 2007-10-01 2009-04-09 Ramniwas Goel Process for the preparation of (s)-ropivacaine hydrochloride monohydrate
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US8412336B2 (en) 2008-12-29 2013-04-02 Autonomic Technologies, Inc. Integrated delivery and visualization tool for a neuromodulation system
US9320908B2 (en) 2009-01-15 2016-04-26 Autonomic Technologies, Inc. Approval per use implanted neurostimulator
US8494641B2 (en) 2009-04-22 2013-07-23 Autonomic Technologies, Inc. Implantable neurostimulator with integral hermetic electronic enclosure, circuit substrate, monolithic feed-through, lead assembly and anchoring mechanism
CA3027255C (en) 2009-07-10 2022-06-21 The General Hospital Corporation Permanently charged sodium and calcium channel blockers as anti-inflammatory agents
RU2504538C2 (ru) * 2012-04-17 2014-01-20 Государственное бюджетное образовательное учреждение высшего профессионального образования "Пермская государственная фармацевтическая академия" Министерства здравоохранения и социального развития Российской Федерации (ГБОУ ВПО ПГФА Минздравсоцразвития России) 2,6-диметиланилид n-циклогексилпирролидин-2-карбоновой кислоты гидрохлорид, проявляющий активность при поверхностной, инфильтрационной и проводниковой анестезии
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CN103304471B (zh) * 2013-07-12 2015-02-04 四川省惠达药业有限公司 一种甲磺酸罗哌卡因化合物、其制备方法及其药物组合物
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US9173877B1 (en) * 2014-11-05 2015-11-03 Cellix Bio Private Limited Compositions and methods for the treatment of local pain
US9932294B2 (en) 2014-12-01 2018-04-03 Cellix Bio Private Limited Compositions and methods for the treatment of multiple sclerosis
ES2905771T3 (es) 2015-01-06 2022-04-12 Cellix Bio Private Ltd Composiciones y procedimientos para el tratamiento de la inflamación y del dolor
AU2016301282B2 (en) 2015-08-03 2022-03-17 Children's Medical Center Corporation Charged ion channel blockers and methods for use
US10786485B1 (en) 2019-03-11 2020-09-29 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use
US10780083B1 (en) 2019-03-11 2020-09-22 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use
JP2022527690A (ja) 2019-03-11 2022-06-03 ノシオン セラピューティクス，インコーポレイテッド 荷電したイオンチャンネル遮断薬および使用方法
MX2021010869A (es) 2019-03-11 2022-01-19 Nocion Therapeutics Inc Bloqueadores de canales iónicos sustituidos por éster y métodos para su uso.
JP2022525856A (ja) 2019-03-11 2022-05-20 ノシオン セラピューティクス，インコーポレイテッド 荷電したイオンチャンネル遮断薬および使用方法
JP2023500891A (ja) 2019-11-06 2023-01-11 ノシオン セラピューティクス，インコーポレイテッド 荷電したイオンチャンネル遮断薬および使用方法
US10933055B1 (en) 2019-11-06 2021-03-02 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use
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Also Published As

Publication number Publication date
CY1623A (en) 1992-07-10
FI851266L (fi) 1985-03-29
MY101904A (en) 1992-02-15
FI80020B (fi) 1989-12-29
FI80020C (fi) 1990-04-10
ATE40994T1 (de) 1989-03-15
JPS60502054A (ja) 1985-11-28
JPH0559903B2 (da) 1993-09-01
DK135685A (da) 1985-03-26
WO1985000599A1 (en) 1985-02-14
DE3379266D1 (en) 1989-04-06
AU560367B2 (en) 1987-04-02
DK153546B (da) 1988-07-25
SG87991G (en) 1991-11-22
FI851266A0 (fi) 1985-03-29
EP0151110B1 (en) 1989-03-01
HK98391A (en) 1991-12-13
AU1779683A (en) 1985-03-04
DK153546C (da) 1988-12-05
EP0151110A1 (en) 1985-08-14

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