DK1356030T3 - RUNX3 gen, som udviser anti-tumor aktivitet, og anvendelse deraf - Google Patents

RUNX3 gen, som udviser anti-tumor aktivitet, og anvendelse deraf

Info

Publication number
DK1356030T3
DK1356030T3 DK01902862T DK01902862T DK1356030T3 DK 1356030 T3 DK1356030 T3 DK 1356030T3 DK 01902862 T DK01902862 T DK 01902862T DK 01902862 T DK01902862 T DK 01902862T DK 1356030 T3 DK1356030 T3 DK 1356030T3
Authority
DK
Denmark
Prior art keywords
runx3
development
cancer
present
runx3 gene
Prior art date
Application number
DK01902862T
Other languages
Danish (da)
English (en)
Inventor
Suk-Chul Bae
Yoshiaki Ito
Original Assignee
Suk-Chul Bae
Yoshiaki Ito
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Suk-Chul Bae, Yoshiaki Ito filed Critical Suk-Chul Bae
Application granted granted Critical
Publication of DK1356030T3 publication Critical patent/DK1356030T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4747—Apoptosis related proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Wood Science & Technology (AREA)
  • Toxicology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Pulmonology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
DK01902862T 2001-01-29 2001-01-30 RUNX3 gen, som udviser anti-tumor aktivitet, og anvendelse deraf DK1356030T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR10-2001-0004018A KR100475649B1 (ko) 2001-01-29 2001-01-29 항암활성을 나타내는 ｒｕｎｘ３ 유전자 및 그의 용도
PCT/KR2001/000121 WO2002061069A1 (en) 2001-01-29 2001-01-30 Runx3 gene showing anti-tumor activity and use thereof

Publications (1)

Publication Number Publication Date
DK1356030T3 true DK1356030T3 (da) 2008-11-03

Family

ID=19705043

Family Applications (1)

Application Number Title Priority Date Filing Date
DK01902862T DK1356030T3 (da) 2001-01-29 2001-01-30 RUNX3 gen, som udviser anti-tumor aktivitet, og anvendelse deraf

Country Status (10)

Country Link
US (2) US7368255B2 (ko)
EP (1) EP1356030B1 (ko)
JP (1) JP4018542B2 (ko)
KR (1) KR100475649B1 (ko)
AT (1) ATE402256T1 (ko)
DE (1) DE60135022D1 (ko)
DK (1) DK1356030T3 (ko)
ES (1) ES2310545T3 (ko)
PT (1) PT1356030E (ko)
WO (1) WO2002061069A1 (ko)

Families Citing this family (55)

* Cited by examiner, † Cited by third party
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US20060078893A1 (en) 2004-10-12 2006-04-13 Medical Research Council Compartmentalised combinatorial chemistry by microfluidic control
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US20050221339A1 (en) 2004-03-31 2005-10-06 Medical Research Council Harvard University Compartmentalised screening by microfluidic control
US7968287B2 (en) 2004-10-08 2011-06-28 Medical Research Council Harvard University In vitro evolution in microfluidic systems
WO2006057623A1 (en) * 2004-11-29 2006-06-01 National University Of Singapore Runx3 antibodies and method of obtaining the antibodies
KR100748185B1 (ko) * 2005-01-31 2007-08-10 한국생명공학연구원 Ｌｒｒｃ3ｂ 유전자를 포함하는 항암용 조성물 및 상기유전자를 이용한 진단방법
US8268572B2 (en) * 2005-03-04 2012-09-18 Dana-Farber Cancer Institute, Inc. Methods to identify inhibitors of Runx1-mediated expression of nociceptive receptors and ion channels
US7611847B2 (en) 2005-06-01 2009-11-03 Agency For Science, Technology And Research Method for identifying an intestinal phenotype
WO2006132248A1 (ja) * 2005-06-07 2006-12-14 Daiichi Pharmaceutical Co., Ltd. Ｒｕｎｘのユビキチン化方法
US20100137163A1 (en) 2006-01-11 2010-06-03 Link Darren R Microfluidic Devices and Methods of Use in The Formation and Control of Nanoreactors
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US9074242B2 (en) 2010-02-12 2015-07-07 Raindance Technologies, Inc. Digital analyte analysis
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WO2008130623A1 (en) 2007-04-19 2008-10-30 Brandeis University Manipulation of fluids, fluid components and reactions in microfluidic systems
US9322065B2 (en) 2007-09-17 2016-04-26 Mdxhealth Sa Methods for determining methylation of the TWIST1 gene for bladder cancer detection
KR20100093523A (ko) * 2007-11-06 2010-08-25 주식회사 프로셀제약 세포투과성 ｒｕｎｘ３ 재조합 단백질, 이를 코딩하는 폴리뉴클레오티드 및 이를 유효성분으로 함유하는 항암 조성물
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EP3808177A1 (en) * 2008-11-10 2021-04-21 Arbutus Biopharma Corporation Novel lipids and compositions for the delivery of therapeutics
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WO2011042564A1 (en) 2009-10-09 2011-04-14 Universite De Strasbourg Labelled silica-based nanomaterial with enhanced properties and uses thereof
US10837883B2 (en) 2009-12-23 2020-11-17 Bio-Rad Laboratories, Inc. Microfluidic systems and methods for reducing the exchange of molecules between droplets
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US10351905B2 (en) 2010-02-12 2019-07-16 Bio-Rad Laboratories, Inc. Digital analyte analysis
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EP3447155A1 (en) 2010-09-30 2019-02-27 Raindance Technologies, Inc. Sandwich assays in droplets
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US9150852B2 (en) 2011-02-18 2015-10-06 Raindance Technologies, Inc. Compositions and methods for molecular labeling
US9556470B2 (en) 2011-06-02 2017-01-31 Raindance Technologies, Inc. Enzyme quantification
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KR101878451B1 (ko) * 2011-09-06 2018-07-16 벤텍스 주식회사 약물전달기능을 갖는 언더웨어
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US9944977B2 (en) 2013-12-12 2018-04-17 Raindance Technologies, Inc. Distinguishing rare variations in a nucleic acid sequence from a sample
WO2015103367A1 (en) 2013-12-31 2015-07-09 Raindance Technologies, Inc. System and method for detection of rna species
US10647981B1 (en) 2015-09-08 2020-05-12 Bio-Rad Laboratories, Inc. Nucleic acid library generation methods and compositions
CN106011263B (zh) * 2016-06-28 2020-01-07 宁波大学 用于检测与胃癌相关的ndrg4基因甲基化程度的试剂盒及其应用
CA3035882A1 (en) 2016-07-29 2018-02-01 Kyoto University Runx inhibitor
US10998178B2 (en) 2017-08-28 2021-05-04 Purdue Research Foundation Systems and methods for sample analysis using swabs
KR101994957B1 (ko) 2017-11-30 2019-07-01 고려대학교 산학협력단 Runx3 단백질 또는 이를 코딩하는 runx3 유전자를 포함하는 trail의 항암 효과 증진용 약학 조성물
WO2019210863A1 (zh) * 2018-05-03 2019-11-07 科济生物医药（上海）有限公司 免疫效应细胞及其应用
JP7144037B2 (ja) * 2018-07-25 2022-09-29 国立大学法人山口大学 がんの診断用バイオマーカー
US20220088126A1 (en) * 2019-01-08 2022-03-24 Biorunx Pharmaceutical composition comprising runx3 gene or protein as active ingredient for prevention or treatment of k-ras mutant lung cancer
CN112662764A (zh) * 2020-03-17 2021-04-16 博尔诚（北京）科技有限公司 一种检测11种癌症的探针组合物
KR20210131855A (ko) * 2020-04-23 2021-11-03 런엑스 주식회사 R-point 조절 단백질 복합체를 유효성분으로 포함하는 폐암 치료용 약학적 조성물, 상기 복합체의 형성 여부를 이용한 폐암 치료제 스크리닝 방법 및 폐암 진단 방법

Also Published As

Publication number Publication date
WO2002061069A1 (en) 2002-08-08
DE60135022D1 (de) 2008-09-04
EP1356030B1 (en) 2008-07-23
US20080261883A1 (en) 2008-10-23
JP4018542B2 (ja) 2007-12-05
JP2004529619A (ja) 2004-09-30
KR100475649B1 (ko) 2005-03-10
ATE402256T1 (de) 2008-08-15
EP1356030A1 (en) 2003-10-29
EP1356030A4 (en) 2005-02-02
US20040146986A1 (en) 2004-07-29
ES2310545T3 (es) 2009-01-16
PT1356030E (pt) 2008-10-30
KR20020063387A (ko) 2002-08-03
US7368255B2 (en) 2008-05-06

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