DK135534B - Fremgangsmåde til fremstilling af pyrasol-(3,4-d)-pyrimidiner eller salte heraf. - Google Patents

Fremgangsmåde til fremstilling af pyrasol-(3,4-d)-pyrimidiner eller salte heraf.

Info

Publication number
DK135534B
DK135534B DK55869AA DK55869A DK135534B DK 135534 B DK135534 B DK 135534B DK 55869A A DK55869A A DK 55869AA DK 55869 A DK55869 A DK 55869A DK 135534 B DK135534 B DK 135534B
Authority
DK
Denmark
Prior art keywords
pyrasol
pyrimidines
salts
preparation
Prior art date
Application number
DK55869AA
Other languages
Danish (da)
English (en)
Other versions
DK135534C (fr
Inventor
Ronald Morton Cresswell
John William Mentha
Russell Seaman
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Found filed Critical Wellcome Found
Priority to DK529774A priority Critical patent/DK135533B/da
Priority to DK39676A priority patent/DK137010B/da
Publication of DK135534B publication Critical patent/DK135534B/da
Application granted granted Critical
Publication of DK135534C publication Critical patent/DK135534C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/38—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DK55869AA 1968-02-02 1969-01-31 Fremgangsmåde til fremstilling af pyrasol-(3,4-d)-pyrimidiner eller salte heraf. DK135534B (da)

Priority Applications (2)

Application Number Priority Date Filing Date Title
DK529774A DK135533B (da) 1968-02-02 1974-10-10 3-Morpholino-2-cyanacrylamidforbindelser og fremgangsmåde til deres fremstilling.
DK39676A DK137010B (da) 1968-02-02 1976-01-30 Fremgangsmåde til fremstilling af 3-amino-4-carbamoyl-pyrazoler eller salte heraf.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB539768A GB1252435A (fr) 1968-02-02 1968-02-02

Publications (2)

Publication Number Publication Date
DK135534B true DK135534B (da) 1977-05-16
DK135534C DK135534C (fr) 1977-10-24

Family

ID=9795384

Family Applications (1)

Application Number Title Priority Date Filing Date
DK55869AA DK135534B (da) 1968-02-02 1969-01-31 Fremgangsmåde til fremstilling af pyrasol-(3,4-d)-pyrimidiner eller salte heraf.

Country Status (18)

Country Link
US (1) US3682957A (fr)
JP (3) JPS509798B1 (fr)
BE (1) BE727754A (fr)
BR (1) BR6906061D0 (fr)
CA (1) CA931568A (fr)
CH (1) CH507266A (fr)
CY (1) CY694A (fr)
DE (3) DE1921676C2 (fr)
DK (1) DK135534B (fr)
ES (2) ES363208A1 (fr)
FR (1) FR2001211A1 (fr)
GB (1) GB1252435A (fr)
GT (1) GT198274955A (fr)
IE (1) IE33130B1 (fr)
IL (2) IL31524A (fr)
MY (1) MY7500063A (fr)
NL (1) NL139664B (fr)
SE (2) SE362429B (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK115374A (fr) 1974-03-04 1975-11-03 Byk Gulden Lomberg Chem Fab
JPS5481278A (en) * 1977-10-18 1979-06-28 Wellcome Found Manufacture of triiseccaminomethane
US4282361A (en) * 1978-03-16 1981-08-04 Massachusetts Institute Of Technology Synthesis for 7-alkylamino-3-methylpyrazolo [4,3-d]pyrimidines
US4267324A (en) * 1979-06-20 1981-05-12 Polaroid Corporation Process for preparing 4-aminopyrazolo-(3,4-d)pyrimidine
CH654009A5 (de) * 1983-03-21 1986-01-31 Siegfried Ag Verfahren zur herstellung von allopurinol.
EP1044002A4 (fr) * 1997-11-07 2003-05-02 Univ Johns Hopkins Procedes de traitement de troubles de la contractilite cardiaque
CN102643279A (zh) * 2012-02-09 2012-08-22 临海市恒源化工有限公司 一种别嘌醇的合成方法
CN103965197B (zh) * 2013-04-15 2016-07-06 杭州领业医药科技有限公司 别嘌醇晶体制备
CN104387394A (zh) * 2014-11-26 2015-03-04 千辉药业（安徽）有限责任公司 一种别嘌醇的制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1070635B (de) 1959-12-10 Ciba Aktiengesellschaft, Basel (Schweiz) Verfahren zur Herstellung von 1,5-unsubstituierten 3-Amiinopymzolen
US3187006A (en) * 1956-04-17 1965-06-01 Ciba Geigy Corp N-substituted pyrazoles and method of preparing same
AT200575B (de) * 1957-01-02 1958-11-10 Ciba Geigy Verfahren zur Herstellung von neuen 3-Amino-pyrazol-derivaten
NL253320A (fr) * 1959-07-03
US3169966A (en) * 1961-01-24 1965-02-16 Ciba Geigy Corp Aminopyrazoles
GB1200444A (en) * 1966-07-14 1970-07-29 Burroughs Wellcome Co The preparation of pyrazoles and pyrazolopyrimidines

Also Published As

Publication number Publication date
GB1252435A (fr) 1971-11-03
IL31524A0 (en) 1969-03-27
GT198274955A (es) 1983-10-18
CH507266A (de) 1971-05-15
DE1904894A1 (de) 1970-01-15
FR2001211A1 (fr) 1969-09-26
DE1966640B2 (de) 1977-08-11
DE1921676A1 (de) 1969-09-18
MY7500063A (en) 1975-12-31
DE1904894B2 (de) 1979-01-18
JPS509798B1 (fr) 1975-04-16
ES380767A1 (es) 1972-09-16
SE380802B (sv) 1975-11-17
IL37414A (en) 1971-11-29
SE362429B (fr) 1973-12-10
DE1904894C3 (de) 1983-06-16
BE727754A (fr) 1969-07-31
CY694A (en) 1973-08-10
JPS523955B1 (fr) 1977-01-31
IE33130B1 (en) 1974-04-03
DE1921676C2 (de) 1985-05-30
NL139664B (nl) 1973-09-17
DE1966640C3 (de) 1985-05-15
US3682957A (en) 1972-08-08
ES363208A1 (es) 1970-12-16
DK135534C (fr) 1977-10-24
IE33130L (en) 1969-08-02
IL31524A (en) 1971-11-29
NL6901564A (fr) 1969-08-05
DE1966640A1 (de) 1973-08-09
CA931568A (en) 1973-08-07
BR6906061D0 (pt) 1973-04-19
JPS5026550B1 (fr) 1975-09-01

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Legal Events

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PUP Patent expired