DK1354884T3 - Cyklopenta[d]pyrazolo[1,5-a]pyrimidinforbindelse som CRF-receptorantagonist - Google Patents
Cyklopenta[d]pyrazolo[1,5-a]pyrimidinforbindelse som CRF-receptorantagonistInfo
- Publication number
- DK1354884T3 DK1354884T3 DK01995808T DK01995808T DK1354884T3 DK 1354884 T3 DK1354884 T3 DK 1354884T3 DK 01995808 T DK01995808 T DK 01995808T DK 01995808 T DK01995808 T DK 01995808T DK 1354884 T3 DK1354884 T3 DK 1354884T3
- Authority
- DK
- Denmark
- Prior art keywords
- ring
- cyclopenta
- pyrazolo
- nitrogen
- receptor antagonist
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
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- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
- C07D487/14—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
- C07D491/14—Ortho-condensed systems
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- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D495/14—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Diabetes (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Immunology (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Addiction (AREA)
- Endocrinology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pulmonology (AREA)
- Hospice & Palliative Care (AREA)
- Obesity (AREA)
- Psychology (AREA)
- Ophthalmology & Optometry (AREA)
- Anesthesiology (AREA)
- Emergency Medicine (AREA)
- Nutrition Science (AREA)
- Otolaryngology (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2000402517 | 2000-12-28 | ||
PCT/JP2001/011581 WO2002053565A1 (fr) | 2000-12-28 | 2001-12-27 | Composes de derives tricycliques et heterocycliques et medicaments renfermant ces composes comme principe actif |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1354884T3 true DK1354884T3 (da) | 2008-03-03 |
Family
ID=18866787
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK01995808T DK1354884T3 (da) | 2000-12-28 | 2001-12-27 | Cyklopenta[d]pyrazolo[1,5-a]pyrimidinforbindelse som CRF-receptorantagonist |
Country Status (24)
Country | Link |
---|---|
US (3) | US7034153B2 (pl) |
EP (2) | EP1354884B1 (pl) |
JP (2) | JP3528968B2 (pl) |
KR (1) | KR100843281B1 (pl) |
CN (2) | CN1274690C (pl) |
AT (2) | ATE375345T1 (pl) |
AU (1) | AU2002226674B2 (pl) |
BR (1) | BR0116609A (pl) |
CA (1) | CA2432148C (pl) |
CZ (1) | CZ20031777A3 (pl) |
DE (1) | DE60130924T2 (pl) |
DK (1) | DK1354884T3 (pl) |
ES (2) | ES2369837T3 (pl) |
HU (1) | HUP0303653A3 (pl) |
IL (2) | IL156609A0 (pl) |
MX (1) | MXPA03005913A (pl) |
NO (1) | NO326522B1 (pl) |
NZ (1) | NZ526712A (pl) |
PL (1) | PL363381A1 (pl) |
PT (1) | PT1354884E (pl) |
RU (1) | RU2291869C2 (pl) |
TW (1) | TWI293630B (pl) |
WO (1) | WO2002053565A1 (pl) |
ZA (1) | ZA200305003B (pl) |
Families Citing this family (32)
Publication number | Priority date | Publication date | Assignee | Title |
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US6562965B1 (en) * | 2000-07-06 | 2003-05-13 | Bristol-Myers Squibb Pharma Company | Convergent synthesis of α-aryl-β-ketonitriles |
ATE375345T1 (de) * | 2000-12-28 | 2007-10-15 | Ono Pharmaceutical Co | Cyclopenta(d)pyrazolo(1,5-a)pyrimidin-verbindun als crf-rezeptor antagonist |
UA80295C2 (en) * | 2002-09-06 | 2007-09-10 | Biogen Inc | Pyrazolopyridines and using the same |
US7129239B2 (en) | 2002-10-28 | 2006-10-31 | Pfizer Inc. | Purine compounds and uses thereof |
US7247628B2 (en) | 2002-12-12 | 2007-07-24 | Pfizer, Inc. | Cannabinoid receptor ligands and uses thereof |
US7329658B2 (en) | 2003-02-06 | 2008-02-12 | Pfizer Inc | Cannabinoid receptor ligands and uses thereof |
US7176210B2 (en) * | 2003-02-10 | 2007-02-13 | Pfizer Inc. | Cannabinoid receptor ligands and uses thereof |
US7141669B2 (en) | 2003-04-23 | 2006-11-28 | Pfizer Inc. | Cannabiniod receptor ligands and uses thereof |
US7268133B2 (en) | 2003-04-23 | 2007-09-11 | Pfizer, Inc. Patent Department | Cannabinoid receptor ligands and uses thereof |
US7145012B2 (en) | 2003-04-23 | 2006-12-05 | Pfizer Inc. | Cannabinoid receptor ligands and uses thereof |
US7232823B2 (en) | 2003-06-09 | 2007-06-19 | Pfizer, Inc. | Cannabinoid receptor ligands and uses thereof |
ES2427166T3 (es) * | 2003-06-23 | 2013-10-29 | Ono Pharmaceutical Co., Ltd. | Compuesto heterocíclico tricíclico novedoso |
NZ544301A (en) * | 2003-06-25 | 2008-08-29 | Ono Pharmaceutical Co | Methanesulfonic acid salt of pyrazolopyrimidine compound, crystal thereof, and process for producing the same |
WO2005061508A1 (ja) * | 2003-12-22 | 2005-07-07 | Ono Pharmaceutical Co., Ltd. | 三環式複素環化合物およびその化合物を有効成分とする医薬 |
WO2005087775A1 (ja) * | 2004-03-15 | 2005-09-22 | Ono Pharmaceutical Co., Ltd. | 三環式複素環化合物およびその化合物を有効成分として含有する医薬組成物 |
US7319103B2 (en) * | 2004-06-30 | 2008-01-15 | Athersys, Inc. | Non-imidazole tertiary amines as histamine 3 receptor inhibitors for the treatment of cognitive and sleep disorders, obesity and other CNS disorders |
US7868037B2 (en) | 2004-07-14 | 2011-01-11 | Ptc Therapeutics, Inc. | Methods for treating hepatitis C |
EP1771169A1 (en) | 2004-07-14 | 2007-04-11 | PTC Therapeutics, Inc. | Methods for treating hepatitis c |
JP2008507518A (ja) | 2004-07-22 | 2008-03-13 | ピーティーシー セラピューティクス,インコーポレーテッド | C型肝炎を治療するためのチエノピリジン |
AR051780A1 (es) * | 2004-11-29 | 2007-02-07 | Japan Tobacco Inc | Compuestos en anillo fusionados que contienen nitrogeno y utilizacion de los mismos |
EP1829874B1 (en) * | 2004-12-22 | 2014-02-12 | Ono Pharmaceutical Co., Ltd. | Tricyclic compound and use thereof |
TW200639163A (en) | 2005-02-04 | 2006-11-16 | Genentech Inc | RAF inhibitor compounds and methods |
JP5431341B2 (ja) * | 2008-01-22 | 2014-03-05 | 武田薬品工業株式会社 | コルチコトロピン放出因子拮抗作用を有する三環系化合物及びそれらを含有する医薬組成物 |
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US5420128A (en) | 1990-10-09 | 1995-05-30 | Otsuka Pharmaceutical Co., Ltd. | Pyrimidine derivatives, method of manufacturing the same, and androgen inhibitor |
CA2206080A1 (en) | 1995-09-28 | 1997-04-03 | Otsuka Pharmaceutical Factory, Inc. | Analgesic composition_of pryazolo{1,5-a}pyrimidine derivatives |
DE69736711T2 (de) | 1996-08-28 | 2007-09-20 | Pfizer Inc. | Substituierte 6,5-heterobicyclische-derivate |
EP1086103B1 (en) * | 1998-06-09 | 2003-05-02 | Neurogen Corporation | Pyrido 2,3-b]indolizine derivatives and aza analogues thereof; crf 1 specific ligands |
WO2000027846A2 (en) * | 1998-11-12 | 2000-05-18 | Neurocrine Biosciences, Inc. | Crf receptor antagonists and methods relating thereto |
IL143105A0 (en) * | 1998-11-12 | 2002-04-21 | Neurocrine Biosciences Inc | Fused polycyclic heterocyclic compounds and pharmaceutical compositions containing the same |
ATE375345T1 (de) * | 2000-12-28 | 2007-10-15 | Ono Pharmaceutical Co | Cyclopenta(d)pyrazolo(1,5-a)pyrimidin-verbindun als crf-rezeptor antagonist |
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2001
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