DK134424B - Fremgangsmåde til fremstilling af et pulver, i det væsentlige indeholdende mikrokapsler af ampicillin-trihydrat eller amoxycillin-trihydrat overtrukket med polyvinylpyrrolidon, ved spraytørring. - Google Patents

Fremgangsmåde til fremstilling af et pulver, i det væsentlige indeholdende mikrokapsler af ampicillin-trihydrat eller amoxycillin-trihydrat overtrukket med polyvinylpyrrolidon, ved spraytørring.

Info

Publication number
DK134424B
DK134424B DK277173AA DK277173A DK134424B DK 134424 B DK134424 B DK 134424B DK 277173A A DK277173A A DK 277173AA DK 277173 A DK277173 A DK 277173A DK 134424 B DK134424 B DK 134424B
Authority
DK
Denmark
Prior art keywords
trihydrate
polyvinylpyrrolidone
powder
preparation
spray drying
Prior art date
Application number
DK277173AA
Other languages
Danish (da)
English (en)
Other versions
DK134424C (es
Inventor
Harry Seager
Original Assignee
Beecham Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group Ltd filed Critical Beecham Group Ltd
Priority to DK692174A priority Critical patent/DK136844B/da
Publication of DK134424B publication Critical patent/DK134424B/da
Application granted granted Critical
Publication of DK134424C publication Critical patent/DK134424C/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5089Processes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2072Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A61K9/2081Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005Wall or coating material
    • A61K9/5021Organic macromolecular compounds
    • A61K9/5026Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005Wall or coating material
    • A61K9/5021Organic macromolecular compounds
    • A61K9/5036Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005Wall or coating material
    • A61K9/5021Organic macromolecular compounds
    • A61K9/5036Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A61K9/5047Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005Wall or coating material
    • A61K9/5021Organic macromolecular compounds
    • A61K9/5052Proteins, e.g. albumin
    • A61K9/5057Gelatin
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02Making microcapsules or microballoons
    • B01J13/04Making microcapsules or microballoons by physical processes, e.g. drying, spraying
    • B01J13/043Drying and spraying
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02Making microcapsules or microballoons
    • B01J13/06Making microcapsules or microballoons by phase separation
    • B01J13/12Making microcapsules or microballoons by phase separation removing solvent from the wall-forming material solution
    • B01J13/125Making microcapsules or microballoons by phase separation removing solvent from the wall-forming material solution by evaporation of the solvent

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK277173AA 1972-05-19 1973-05-17 Fremgangsmåde til fremstilling af et pulver, i det væsentlige indeholdende mikrokapsler af ampicillin-trihydrat eller amoxycillin-trihydrat overtrukket med polyvinylpyrrolidon, ved spraytørring. DK134424B (da)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DK692174A DK136844B (da) 1972-05-19 1974-12-30 Fremgangsmåde til fremstilling af et farmaceutisk præparat indeholdende amoxycillin-trihydrat eller ampicillin-trihydrat i en dosisform, som kan anvendes til human eller veterinær administration.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB2357672A GB1403584A (en) 1972-05-19 1972-05-19 Control medicaments

Publications (2)

Publication Number Publication Date
DK134424B true DK134424B (da) 1976-11-08
DK134424C DK134424C (es) 1977-05-23

Family

ID=10197917

Family Applications (2)

Application Number Title Priority Date Filing Date
DK277173AA DK134424B (da) 1972-05-19 1973-05-17 Fremgangsmåde til fremstilling af et pulver, i det væsentlige indeholdende mikrokapsler af ampicillin-trihydrat eller amoxycillin-trihydrat overtrukket med polyvinylpyrrolidon, ved spraytørring.
DK190774A DK134423C (da) 1972-05-19 1974-04-05 Apparat til optagelse af et ultralyd-snitbillede

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK190774A DK134423C (da) 1972-05-19 1974-04-05 Apparat til optagelse af et ultralyd-snitbillede

Country Status (16)

Country Link
JP (2) JPS4954518A (es)
AR (1) AR197900A1 (es)
AT (1) AT337902B (es)
AU (1) AU475493B2 (es)
BE (1) BE799783A (es)
CA (1) CA1025359A (es)
DE (1) DE2325410A1 (es)
DK (2) DK134424B (es)
ES (1) ES414908A1 (es)
FR (1) FR2185390B1 (es)
GB (1) GB1403584A (es)
HU (1) HU167559B (es)
IE (1) IE37637B1 (es)
IL (1) IL42312A (es)
NL (1) NL7307033A (es)
ZA (1) ZA733406B (es)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK153123B (da) * 1975-03-07 1988-06-20 Beecham Group Ltd Fremgangsmaade til fremstilling af et pulverformigt farmaceutisk praeparat indeholdende amoxycillin-trihydrat

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1403584A (en) * 1972-05-19 1975-08-28 Beecham Group Ltd Control medicaments
JPS5446001U (es) * 1977-09-07 1979-03-30
FR2403080A1 (fr) * 1977-09-15 1979-04-13 Heyden Chem Fab Preparation de nitrofurantoine a effet retard pour administration orale et son procede de fabrication
DE2805106A1 (de) * 1978-02-07 1979-08-16 Hoechst Ag Mikrokapseln aus polyvinylalkohol mit fluessigem, wasserunloeslichem fuellgut und verfahren zu deren herstellung
JPS56156214A (en) * 1980-05-02 1981-12-02 Yoshiaki Kawashima Preparation of tableting enteric microcapsule
JPS5867616A (ja) * 1981-10-15 1983-04-22 Tanabe Seiyaku Co Ltd 腸溶性マイクロカプセル
US4370313A (en) * 1981-10-26 1983-01-25 Eaton Laboratories, Inc. Nitrofurantoin dosage form
HU187215B (en) * 1983-01-26 1985-11-28 Egyt Gyogyszervegyeszeti Gyar Method for producing pharmaceutical product of high actor content and prolonged effect
SE8404808L (sv) * 1983-10-03 1985-04-04 Avner Rotman Mikrokapslat lekemedel i sot matris
IE58110B1 (en) * 1984-10-30 1993-07-14 Elan Corp Plc Controlled release powder and process for its preparation
JPS61218516A (ja) * 1985-03-25 1986-09-29 Ichimaru Fuarukosu Kk 徐放性マイクロカプセルの製造法
IT1230095B (it) * 1989-04-27 1991-10-05 Parenta Srl Procedimento per la preparazione di forme sterili di polveri iniettabili di antibiotici.
ES2071049T3 (es) * 1990-11-29 1995-06-16 Faulding F H & Co Ltd Procedimiento para producir polvos cargados de liquido.
SE9903236D0 (sv) * 1999-09-10 1999-09-10 Astra Ab Method to obtain microparticles

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7112083A (es) * 1970-09-16 1972-03-20
GB1403584A (en) * 1972-05-19 1975-08-28 Beecham Group Ltd Control medicaments

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK153123B (da) * 1975-03-07 1988-06-20 Beecham Group Ltd Fremgangsmaade til fremstilling af et pulverformigt farmaceutisk praeparat indeholdende amoxycillin-trihydrat

Also Published As

Publication number Publication date
AU475493B2 (en) 1976-08-26
JPS4954518A (es) 1974-05-27
JPS49116220A (es) 1974-11-06
BE799783A (fr) 1973-11-19
HU167559B (es) 1975-11-28
DK134423B (da) 1976-11-08
DK190774A (da) 1975-10-06
IE37637B1 (en) 1977-09-14
IL42312A0 (en) 1973-07-30
ZA733406B (en) 1975-03-26
ES414908A1 (es) 1976-06-01
AT337902B (de) 1977-07-25
AU5596573A (en) 1974-11-21
ATA439473A (de) 1976-11-15
FR2185390B1 (es) 1977-04-15
FR2185390A1 (es) 1974-01-04
DK134423C (da) 1977-04-12
CA1025359A (en) 1978-01-31
AR197900A1 (es) 1974-05-15
GB1403584A (en) 1975-08-28
IL42312A (en) 1977-01-31
NL7307033A (es) 1973-11-21
IE37637L (en) 1973-11-19
DK134424C (es) 1977-05-23
DE2325410A1 (de) 1973-11-29

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