DK134424B - Process for the preparation of a powder, essentially containing microcapsules of ampicillin trihydrate or amoxycillin trihydrate coated with polyvinylpyrrolidone, by spray drying. - Google Patents

Process for the preparation of a powder, essentially containing microcapsules of ampicillin trihydrate or amoxycillin trihydrate coated with polyvinylpyrrolidone, by spray drying.

Info

Publication number
DK134424B
DK134424B DK277173AA DK277173A DK134424B DK 134424 B DK134424 B DK 134424B DK 277173A A DK277173A A DK 277173AA DK 277173 A DK277173 A DK 277173A DK 134424 B DK134424 B DK 134424B
Authority
DK
Denmark
Prior art keywords
trihydrate
polyvinylpyrrolidone
powder
preparation
spray drying
Prior art date
Application number
DK277173AA
Other languages
Danish (da)
Other versions
DK134424C (en
Inventor
Harry Seager
Original Assignee
Beecham Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group Ltd filed Critical Beecham Group Ltd
Priority to DK692174A priority Critical patent/DK136844B/en
Publication of DK134424B publication Critical patent/DK134424B/en
Application granted granted Critical
Publication of DK134424C publication Critical patent/DK134424C/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5089—Processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5052—Proteins, e.g. albumin
    • A61K9/5057—Gelatin
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B01J13/04—Making microcapsules or microballoons by physical processes, e.g. drying, spraying
    • B01J13/043—Drying and spraying
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B01J13/06—Making microcapsules or microballoons by phase separation
    • B01J13/12—Making microcapsules or microballoons by phase separation removing solvent from the wall-forming material solution
    • B01J13/125—Making microcapsules or microballoons by phase separation removing solvent from the wall-forming material solution by evaporation of the solvent

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK277173AA 1972-05-19 1973-05-17 Process for the preparation of a powder, essentially containing microcapsules of ampicillin trihydrate or amoxycillin trihydrate coated with polyvinylpyrrolidone, by spray drying. DK134424B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DK692174A DK136844B (en) 1972-05-19 1974-12-30 A process for the preparation of a pharmaceutical composition containing amoxycillin trihydrate or ampicillin trihydrate in a dosage form which can be used for human or veterinary administration.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB2357672A GB1403584A (en) 1972-05-19 1972-05-19 Control medicaments

Publications (2)

Publication Number Publication Date
DK134424B true DK134424B (en) 1976-11-08
DK134424C DK134424C (en) 1977-05-23

Family

ID=10197917

Family Applications (2)

Application Number Title Priority Date Filing Date
DK277173AA DK134424B (en) 1972-05-19 1973-05-17 Process for the preparation of a powder, essentially containing microcapsules of ampicillin trihydrate or amoxycillin trihydrate coated with polyvinylpyrrolidone, by spray drying.
DK190774A DK134423C (en) 1972-05-19 1974-04-05 APPARATUS FOR RECORDING AN ULTRASOUND SCREEN

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK190774A DK134423C (en) 1972-05-19 1974-04-05 APPARATUS FOR RECORDING AN ULTRASOUND SCREEN

Country Status (16)

Country Link
JP (2) JPS4954518A (en)
AR (1) AR197900A1 (en)
AT (1) AT337902B (en)
AU (1) AU475493B2 (en)
BE (1) BE799783A (en)
CA (1) CA1025359A (en)
DE (1) DE2325410A1 (en)
DK (2) DK134424B (en)
ES (1) ES414908A1 (en)
FR (1) FR2185390B1 (en)
GB (1) GB1403584A (en)
HU (1) HU167559B (en)
IE (1) IE37637B1 (en)
IL (1) IL42312A (en)
NL (1) NL7307033A (en)
ZA (1) ZA733406B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK153123B (en) * 1975-03-07 1988-06-20 Beecham Group Ltd METHOD FOR PREPARING A POWDER-PHARMACEUTICAL PREPARATION CONTAINING AMOXYCILLIN TRIHYDRATE

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1403584A (en) * 1972-05-19 1975-08-28 Beecham Group Ltd Control medicaments
JPS5446001U (en) * 1977-09-07 1979-03-30
FR2403080A1 (en) * 1977-09-15 1979-04-13 Heyden Chem Fab Slow-release nitro:furantoin compsn. useful as urinary antiseptic - comprises three types of granulate with different solubilities
DE2805106A1 (en) * 1978-02-07 1979-08-16 Hoechst Ag MICROCAPSULES MADE OF POLYVINYL ALCOHOL WITH LIQUID, WATER-INSOLUBLE FILLING MATERIAL AND PROCESS FOR THEIR PRODUCTION
JPS56156214A (en) * 1980-05-02 1981-12-02 Yoshiaki Kawashima Preparation of tableting enteric microcapsule
JPS5867616A (en) * 1981-10-15 1983-04-22 Tanabe Seiyaku Co Ltd Enteric microcapsule and its preparation
US4370313A (en) * 1981-10-26 1983-01-25 Eaton Laboratories, Inc. Nitrofurantoin dosage form
HU187215B (en) * 1983-01-26 1985-11-28 Egyt Gyogyszervegyeszeti Gyar Method for producing pharmaceutical product of high actor content and prolonged effect
SE8404808L (en) * 1983-10-03 1985-04-04 Avner Rotman MICROCAPCLE PLATE MEDICINE IN SOT MATRIX
IE58110B1 (en) * 1984-10-30 1993-07-14 Elan Corp Plc Controlled release powder and process for its preparation
JPS61218516A (en) * 1985-03-25 1986-09-29 Ichimaru Fuarukosu Kk Production of sustained release microcapsule
IT1230095B (en) * 1989-04-27 1991-10-05 Parenta Srl PROCEDURE FOR THE PREPARATION OF STERILE FORMS OF INJECTABLE POWDERS OF ANTIBIOTICS.
ES2071049T3 (en) * 1990-11-29 1995-06-16 Faulding F H & Co Ltd PROCEDURE FOR PRODUCING LIQUID LOADED POWDERS.
SE9903236D0 (en) * 1999-09-10 1999-09-10 Astra Ab Method of obtaining microparticles

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7112083A (en) * 1970-09-16 1972-03-20
GB1403584A (en) * 1972-05-19 1975-08-28 Beecham Group Ltd Control medicaments

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK153123B (en) * 1975-03-07 1988-06-20 Beecham Group Ltd METHOD FOR PREPARING A POWDER-PHARMACEUTICAL PREPARATION CONTAINING AMOXYCILLIN TRIHYDRATE

Also Published As

Publication number Publication date
AU475493B2 (en) 1976-08-26
JPS4954518A (en) 1974-05-27
JPS49116220A (en) 1974-11-06
BE799783A (en) 1973-11-19
HU167559B (en) 1975-11-28
DK134423B (en) 1976-11-08
DK190774A (en) 1975-10-06
IE37637B1 (en) 1977-09-14
IL42312A0 (en) 1973-07-30
ZA733406B (en) 1975-03-26
ES414908A1 (en) 1976-06-01
AT337902B (en) 1977-07-25
AU5596573A (en) 1974-11-21
ATA439473A (en) 1976-11-15
FR2185390B1 (en) 1977-04-15
FR2185390A1 (en) 1974-01-04
DK134423C (en) 1977-04-12
CA1025359A (en) 1978-01-31
AR197900A1 (en) 1974-05-15
GB1403584A (en) 1975-08-28
IL42312A (en) 1977-01-31
NL7307033A (en) 1973-11-21
IE37637L (en) 1973-11-19
DK134424C (en) 1977-05-23
DE2325410A1 (en) 1973-11-29

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