ES414908A1 - Un procedimiento para la preparacion de un polvo que com- prende microcapsulas. - Google Patents

Un procedimiento para la preparacion de un polvo que com- prende microcapsulas.

Info

Publication number
ES414908A1
ES414908A1 ES414908A ES414908A ES414908A1 ES 414908 A1 ES414908 A1 ES 414908A1 ES 414908 A ES414908 A ES 414908A ES 414908 A ES414908 A ES 414908A ES 414908 A1 ES414908 A1 ES 414908A1
Authority
ES
Spain
Prior art keywords
suspension
microcapsules
lactam
agent
antibiotic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES414908A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beecham Group PLC
Original Assignee
Beecham Group PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group PLC filed Critical Beecham Group PLC
Publication of ES414908A1 publication Critical patent/ES414908A1/es
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5089—Processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5052—Proteins, e.g. albumin
    • A61K9/5057—Gelatin
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B01J13/04—Making microcapsules or microballoons by physical processes, e.g. drying, spraying
    • B01J13/043—Drying and spraying
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B01J13/06—Making microcapsules or microballoons by phase separation
    • B01J13/12—Making microcapsules or microballoons by phase separation removing solvent from the wall-forming material solution
    • B01J13/125—Making microcapsules or microballoons by phase separation removing solvent from the wall-forming material solution by evaporation of the solvent

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ES414908A 1972-05-19 1973-05-18 Un procedimiento para la preparacion de un polvo que com- prende microcapsulas. Expired ES414908A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB2357672A GB1403584A (en) 1972-05-19 1972-05-19 Control medicaments

Publications (1)

Publication Number Publication Date
ES414908A1 true ES414908A1 (es) 1976-06-01

Family

ID=10197917

Family Applications (1)

Application Number Title Priority Date Filing Date
ES414908A Expired ES414908A1 (es) 1972-05-19 1973-05-18 Un procedimiento para la preparacion de un polvo que com- prende microcapsulas.

Country Status (16)

Country Link
JP (2) JPS4954518A (es)
AR (1) AR197900A1 (es)
AT (1) AT337902B (es)
AU (1) AU475493B2 (es)
BE (1) BE799783A (es)
CA (1) CA1025359A (es)
DE (1) DE2325410A1 (es)
DK (2) DK134424B (es)
ES (1) ES414908A1 (es)
FR (1) FR2185390B1 (es)
GB (1) GB1403584A (es)
HU (1) HU167559B (es)
IE (1) IE37637B1 (es)
IL (1) IL42312A (es)
NL (1) NL7307033A (es)
ZA (1) ZA733406B (es)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1403584A (en) * 1972-05-19 1975-08-28 Beecham Group Ltd Control medicaments
GB1532993A (en) * 1975-03-07 1978-11-22 Beecham Group Ltd Injectable antibiotic compositions
JPS5446001U (es) * 1977-09-07 1979-03-30
FR2403080A1 (fr) * 1977-09-15 1979-04-13 Heyden Chem Fab Preparation de nitrofurantoine a effet retard pour administration orale et son procede de fabrication
DE2805106A1 (de) * 1978-02-07 1979-08-16 Hoechst Ag Mikrokapseln aus polyvinylalkohol mit fluessigem, wasserunloeslichem fuellgut und verfahren zu deren herstellung
JPS56156214A (en) * 1980-05-02 1981-12-02 Yoshiaki Kawashima Preparation of tableting enteric microcapsule
JPS5867616A (ja) * 1981-10-15 1983-04-22 Tanabe Seiyaku Co Ltd 腸溶性マイクロカプセル
US4370313A (en) * 1981-10-26 1983-01-25 Eaton Laboratories, Inc. Nitrofurantoin dosage form
HU187215B (en) * 1983-01-26 1985-11-28 Egyt Gyogyszervegyeszeti Gyar Method for producing pharmaceutical product of high actor content and prolonged effect
SE8404808L (sv) * 1983-10-03 1985-04-04 Avner Rotman Mikrokapslat lekemedel i sot matris
IE58110B1 (en) * 1984-10-30 1993-07-14 Elan Corp Plc Controlled release powder and process for its preparation
JPS61218516A (ja) * 1985-03-25 1986-09-29 Ichimaru Fuarukosu Kk 徐放性マイクロカプセルの製造法
IT1230095B (it) * 1989-04-27 1991-10-05 Parenta Srl Procedimento per la preparazione di forme sterili di polveri iniettabili di antibiotici.
ES2071049T3 (es) * 1990-11-29 1995-06-16 Faulding F H & Co Ltd Procedimiento para producir polvos cargados de liquido.
SE9903236D0 (sv) * 1999-09-10 1999-09-10 Astra Ab Method to obtain microparticles

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7112083A (es) * 1970-09-16 1972-03-20
GB1403584A (en) * 1972-05-19 1975-08-28 Beecham Group Ltd Control medicaments

Also Published As

Publication number Publication date
AU475493B2 (en) 1976-08-26
JPS4954518A (es) 1974-05-27
JPS49116220A (es) 1974-11-06
BE799783A (fr) 1973-11-19
HU167559B (es) 1975-11-28
DK134423B (da) 1976-11-08
DK190774A (da) 1975-10-06
IE37637B1 (en) 1977-09-14
IL42312A0 (en) 1973-07-30
ZA733406B (en) 1975-03-26
DK134424B (da) 1976-11-08
AT337902B (de) 1977-07-25
AU5596573A (en) 1974-11-21
ATA439473A (de) 1976-11-15
FR2185390B1 (es) 1977-04-15
FR2185390A1 (es) 1974-01-04
DK134423C (da) 1977-04-12
CA1025359A (en) 1978-01-31
AR197900A1 (es) 1974-05-15
GB1403584A (en) 1975-08-28
IL42312A (en) 1977-01-31
NL7307033A (es) 1973-11-21
IE37637L (en) 1973-11-19
DK134424C (es) 1977-05-23
DE2325410A1 (de) 1973-11-29

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