IT1230095B - Procedimento per la preparazione di forme sterili di polveri iniettabili di antibiotici. - Google Patents

Procedimento per la preparazione di forme sterili di polveri iniettabili di antibiotici.

Info

Publication number
IT1230095B
IT1230095B IT8920292A IT2029289A IT1230095B IT 1230095 B IT1230095 B IT 1230095B IT 8920292 A IT8920292 A IT 8920292A IT 2029289 A IT2029289 A IT 2029289A IT 1230095 B IT1230095 B IT 1230095B
Authority
IT
Italy
Prior art keywords
antibiotics
procedure
preparation
injectable powders
sterile forms
Prior art date
Application number
IT8920292A
Other languages
English (en)
Other versions
IT8920292A0 (it
Inventor
Flavio Dusci
Original Assignee
Parenta Srl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Parenta Srl filed Critical Parenta Srl
Priority to IT8920292A priority Critical patent/IT1230095B/it
Publication of IT8920292A0 publication Critical patent/IT8920292A0/it
Priority to CA002012727A priority patent/CA2012727A1/en
Priority to DE4011956A priority patent/DE4011956A1/de
Priority to GB9008756A priority patent/GB2231266A/en
Priority to ES9001152A priority patent/ES2019560A6/es
Priority to JP2108954A priority patent/JPH02295926A/ja
Application granted granted Critical
Publication of IT1230095B publication Critical patent/IT1230095B/it

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/429—Thiazoles condensed with heterocyclic ring systems
    • A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D1/00—Evaporating
    • B01D1/16—Evaporating by spraying
    • B01D1/18—Evaporating by spraying to obtain dry solids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dermatology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
IT8920292A 1989-04-27 1989-04-27 Procedimento per la preparazione di forme sterili di polveri iniettabili di antibiotici. IT1230095B (it)

Priority Applications (6)

Application Number Priority Date Filing Date Title
IT8920292A IT1230095B (it) 1989-04-27 1989-04-27 Procedimento per la preparazione di forme sterili di polveri iniettabili di antibiotici.
CA002012727A CA2012727A1 (en) 1989-04-27 1990-03-21 Process and an apparatus for the preparation of sterile injectable powders of antibiotics
DE4011956A DE4011956A1 (de) 1989-04-27 1990-04-12 Verfahren und vorrichtung zur darstellung von sterilen einspritzbaren antibiotikapulvern
GB9008756A GB2231266A (en) 1989-04-27 1990-04-19 The preparation of sterile powders of antibiotics
ES9001152A ES2019560A6 (es) 1989-04-27 1990-04-24 Procedimiento de preparar polvos esteriles inyectables de antibioticos y aparato correspondiente.
JP2108954A JPH02295926A (ja) 1989-04-27 1990-04-26 抗生物質の無菌性注入可能粉末の調製のための方法及び装置

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8920292A IT1230095B (it) 1989-04-27 1989-04-27 Procedimento per la preparazione di forme sterili di polveri iniettabili di antibiotici.

Publications (2)

Publication Number Publication Date
IT8920292A0 IT8920292A0 (it) 1989-04-27
IT1230095B true IT1230095B (it) 1991-10-05

Family

ID=11165487

Family Applications (1)

Application Number Title Priority Date Filing Date
IT8920292A IT1230095B (it) 1989-04-27 1989-04-27 Procedimento per la preparazione di forme sterili di polveri iniettabili di antibiotici.

Country Status (6)

Country Link
JP (1) JPH02295926A (it)
CA (1) CA2012727A1 (it)
DE (1) DE4011956A1 (it)
ES (1) ES2019560A6 (it)
GB (1) GB2231266A (it)
IT (1) IT1230095B (it)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL372247A1 (en) 2002-02-01 2005-07-11 Pfizer Products Inc. Method for making homogeneous spray-dried solid amorphous drug dispersions utilizing modified spray-drying apparatus
GB2404880B (en) 2003-07-25 2005-10-12 Ultrasound Brewery Ultrasonic solution separator
CL2004001884A1 (es) 2003-08-04 2005-06-03 Pfizer Prod Inc Procedimiento de secado por pulverizacion para la formacion de dispersiones solidas amorfas de un farmaco y polimeros.
CN101299995B (zh) * 2005-12-05 2013-04-24 桑多斯股份公司 重构后稳定性提高的冻干哌拉西林钠的制备方法
WO2009081751A1 (ja) * 2007-12-21 2009-07-02 Nipro Corporation 抗生物質製剤の新規製造法
CN102372728B (zh) * 2011-11-28 2013-12-11 齐鲁安替制药有限公司 一种头孢菌素类化合物的合成方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1403584A (en) * 1972-05-19 1975-08-28 Beecham Group Ltd Control medicaments
GB1479655A (en) * 1974-03-08 1977-07-13 Beecham Group Ltd Antibiotic preparations
GB1532993A (en) * 1975-03-07 1978-11-22 Beecham Group Ltd Injectable antibiotic compositions
YU44680B (en) * 1982-07-30 1990-12-31 Glaxo Lab Ltd Process for obtaining very pure amorphous form of cephuroxim axetile

Also Published As

Publication number Publication date
CA2012727A1 (en) 1990-10-27
JPH02295926A (ja) 1990-12-06
IT8920292A0 (it) 1989-04-27
ES2019560A6 (es) 1991-06-16
GB9008756D0 (en) 1990-06-13
GB2231266A (en) 1990-11-14
DE4011956A1 (de) 1990-10-31

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