DK1342794T3 - Fremgangsmåde og anordning til at bestemme vævsspecificitet af fritflydende DNA i legemsvæsker - Google Patents

Fremgangsmåde og anordning til at bestemme vævsspecificitet af fritflydende DNA i legemsvæsker

Info

Publication number
DK1342794T3
DK1342794T3 DK02004954T DK02004954T DK1342794T3 DK 1342794 T3 DK1342794 T3 DK 1342794T3 DK 02004954 T DK02004954 T DK 02004954T DK 02004954 T DK02004954 T DK 02004954T DK 1342794 T3 DK1342794 T3 DK 1342794T3
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DK
Denmark
Prior art keywords
dna
amount
free floating
free
body fluids
Prior art date
Application number
DK02004954T
Other languages
Danish (da)
English (en)
Inventor
Kurt Berlin
Andrzej Sledziewski
Original Assignee
Epigenomics Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Epigenomics Ag filed Critical Epigenomics Ag
Application granted granted Critical
Publication of DK1342794T3 publication Critical patent/DK1342794T3/da

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1003Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
DK02004954T 2002-03-05 2002-03-05 Fremgangsmåde og anordning til at bestemme vævsspecificitet af fritflydende DNA i legemsvæsker DK1342794T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP02004954A EP1342794B1 (en) 2002-03-05 2002-03-05 Method and device for determination of tissue specificity of free floating DNA in bodily fluids

Publications (1)

Publication Number Publication Date
DK1342794T3 true DK1342794T3 (da) 2006-04-24

Family

ID=27741132

Family Applications (1)

Application Number Title Priority Date Filing Date
DK02004954T DK1342794T3 (da) 2002-03-05 2002-03-05 Fremgangsmåde og anordning til at bestemme vævsspecificitet af fritflydende DNA i legemsvæsker

Country Status (10)

Country Link
US (1) US20050221314A1 (ja)
EP (2) EP1342794B1 (ja)
JP (1) JP4727149B2 (ja)
AT (1) ATE312946T1 (ja)
AU (1) AU2003218691B2 (ja)
CA (1) CA2478493A1 (ja)
DE (1) DE60207979T2 (ja)
DK (1) DK1342794T3 (ja)
ES (1) ES2253461T3 (ja)
WO (1) WO2003074730A1 (ja)

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US9732390B2 (en) 2012-09-20 2017-08-15 The Chinese University Of Hong Kong Non-invasive determination of methylome of fetus or tumor from plasma
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US20170145475A1 (en) 2015-11-20 2017-05-25 Streck, Inc. Single spin process for blood plasma separation and plasma composition including preservative
CN108603228B (zh) 2015-12-17 2023-09-01 夸登特健康公司 通过分析无细胞dna确定肿瘤基因拷贝数的方法
CN109072300B (zh) * 2015-12-17 2023-01-31 伊路敏纳公司 区分复杂生物样品中的甲基化水平
US11299783B2 (en) 2016-05-27 2022-04-12 Personalis, Inc. Methods and systems for genetic analysis
CN115161390A (zh) 2016-05-30 2022-10-11 香港中文大学 使用血液中的无细胞dna检测血液病症
WO2018031760A1 (en) 2016-08-10 2018-02-15 Grail, Inc. Methods of preparing dual-indexed dna libraries for bisulfite conversion sequencing
ES2840003T3 (es) 2016-09-30 2021-07-06 Guardant Health Inc Métodos para análisis multi-resolución de ácidos nucleicos libres de células
US9850523B1 (en) 2016-09-30 2017-12-26 Guardant Health, Inc. Methods for multi-resolution analysis of cell-free nucleic acids
WO2018081130A1 (en) 2016-10-24 2018-05-03 The Chinese University Of Hong Kong Methods and systems for tumor detection
KR20230062684A (ko) 2016-11-30 2023-05-09 더 차이니즈 유니버시티 오브 홍콩 소변 및 기타 샘플에서의 무세포 dna의 분석
TW202348802A (zh) 2017-01-25 2023-12-16 香港中文大學 使用核酸片段之診斷應用
EP3366780B1 (en) * 2017-02-23 2020-05-06 Siemens Healthcare GmbH Single-molecule sequence and high sensitivity methylation analysis for tissue-specific analysis
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Also Published As

Publication number Publication date
ATE312946T1 (de) 2005-12-15
EP1342794A1 (en) 2003-09-10
CA2478493A1 (en) 2003-09-12
DE60207979D1 (de) 2006-01-19
ES2253461T3 (es) 2006-06-01
AU2003218691A1 (en) 2003-09-16
EP1342794B1 (en) 2005-12-14
AU2003218691B2 (en) 2008-06-12
EP1483410A1 (en) 2004-12-08
DE60207979T2 (de) 2006-09-28
JP4727149B2 (ja) 2011-07-20
JP2005518809A (ja) 2005-06-30
WO2003074730A1 (en) 2003-09-12
US20050221314A1 (en) 2005-10-06

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