DK1327637T3 - Fremgangsmåde til fremstilling af L-Ribose - Google Patents

Fremgangsmåde til fremstilling af L-Ribose

Info

Publication number
DK1327637T3
DK1327637T3 DK03075945T DK03075945T DK1327637T3 DK 1327637 T3 DK1327637 T3 DK 1327637T3 DK 03075945 T DK03075945 T DK 03075945T DK 03075945 T DK03075945 T DK 03075945T DK 1327637 T3 DK1327637 T3 DK 1327637T3
Authority
DK
Denmark
Prior art keywords
ribose
preparing
Prior art date
Application number
DK03075945T
Other languages
Danish (da)
English (en)
Inventor
Yong S Choi
Jinfa Du
Chung K Chu
Original Assignee
Univ Georgia Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Georgia Res Found filed Critical Univ Georgia Res Found
Application granted granted Critical
Publication of DK1327637T3 publication Critical patent/DK1327637T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H9/00Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical
    • C07H9/02Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical the hetero ring containing only oxygen as ring hetero atoms
    • C07H9/04Cyclic acetals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06Pyrimidine radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H3/00Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
    • C07H3/02Monosaccharides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
DK03075945T 1997-07-23 1998-07-23 Fremgangsmåde til fremstilling af L-Ribose DK1327637T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US5348897P 1997-07-23 1997-07-23

Publications (1)

Publication Number Publication Date
DK1327637T3 true DK1327637T3 (da) 2006-01-16

Family

ID=21984622

Family Applications (1)

Application Number Title Priority Date Filing Date
DK03075945T DK1327637T3 (da) 1997-07-23 1998-07-23 Fremgangsmåde til fremstilling af L-Ribose

Country Status (21)

Country Link
US (2) US6512107B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
EP (2) EP0998482B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
KR (1) KR100247505B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CN (1) CN1113892C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AR (1) AR009092A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AT (2) ATE304547T1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU (1) AU8758298A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
BR (1) BR9810804B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (2) DE69812959T2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DK (1) DK1327637T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (2) ES2195370T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ID (1) ID20624A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IL (1) IL121730A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IN (1) IN186807B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
MY (1) MY117314A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PT (2) PT998482E (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
SA (1) SA98180771B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
SI (1) SI1327637T1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
TR (1) TR199701051A2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
TW (1) TW434252B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
WO (2) WO1999005157A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW434252B (en) 1997-07-23 2001-05-16 Univ Georgia Res Found Process for the preparation of 2'-fluoro-5-methyl-β-L-arabino-furanosyluridine
KR100449618B1 (ko) * 1998-03-27 2004-11-16 부광약품 주식회사 2'-플루오로-5-메틸-β-L-아라비노푸라노실유리딘의 제조방법
US6462191B1 (en) * 2000-07-13 2002-10-08 Air Products And Chemicals, Inc. Synthesis of 2-deoxy-2-fluoro-arabinose derivatives
ATE298759T1 (de) * 2001-03-30 2005-07-15 Gilead Sciences Inc Verfahren zur herstellung von 2'-fluoro-beta-l- arabinofuranosylnukleosiden
KR100487992B1 (ko) * 2001-10-25 2005-05-09 부광약품 주식회사 2'-플루오로-5-메틸-β-엘-아라비노푸라노실유리딘의 황유도체
US7211570B2 (en) * 2001-12-20 2007-05-01 Pharmasset, Inc. Treatment of EBV and KHSV infection
KR100976778B1 (ko) 2003-04-17 2010-08-18 부광약품 주식회사 1-(2'-플루오로-베타-엘-아라비노푸라노실)티민의 황 유도체를 유효 활성 성분으로 하는 b형 간염 바이러스 치료제
PL3109244T3 (pl) 2004-09-14 2019-09-30 Gilead Pharmasset Llc Wytwarzanie 2'fluoro-2'-alkilo-podstawionych lub innych ewentualnie podstawionych rybofuranozylopirymidyn i puryn oraz ich pochodnych
CN103735560A (zh) * 2005-06-07 2014-04-23 耶鲁大学 使用克来夫定和替比夫定治疗癌症和其它病症或疾病状态的方法
US8236797B2 (en) 2007-06-18 2012-08-07 Sunshine Lake Pharma Co., Ltd. Bromo-phenyl substituted thiazolyl dihydropyrimidines
GB0907551D0 (en) 2009-05-01 2009-06-10 Univ Dundee Treatment or prophylaxis of proliferative conditions
CN112135634A (zh) 2018-02-02 2020-12-25 马福瑞克斯肿瘤学股份有限公司 单磷酸吉西他滨的小分子药物偶联物
CN109320564B (zh) * 2018-10-26 2022-05-31 浙江晟格生物科技有限公司 一种l-来苏糖的制备工艺
CN109467541A (zh) * 2018-11-17 2019-03-15 扬州工业职业技术学院 一种绿色合成克拉夫定药物中间体的方法
CN109467583A (zh) * 2018-11-17 2019-03-15 扬州工业职业技术学院 一种克拉夫定的绿色合成工艺

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3714473A1 (de) * 1987-04-30 1988-11-10 Basf Ag Kontinuierliches verfahren zur epimerisierung von zuckern, insbesondere von d-arabinose zu d-ribose
JP2784230B2 (ja) 1988-02-09 1998-08-06 ユーオーピー・インコーポレーテッド エピマーアルドースおよびアルドース同族体の連続相互変換に用いる固体触媒
DE4002727A1 (de) * 1990-01-31 1991-08-01 Bayer Ag Mischungen aus waessrigen polymerdispersionen
US5587362A (en) * 1994-01-28 1996-12-24 Univ. Of Ga Research Foundation L-nucleosides
US5808040A (en) 1995-01-30 1998-09-15 Yale University L-nucleosides incorporated into polymeric structure for stabilization of oligonucleotides
TW434252B (en) * 1997-07-23 2001-05-16 Univ Georgia Res Found Process for the preparation of 2'-fluoro-5-methyl-β-L-arabino-furanosyluridine

Also Published As

Publication number Publication date
PT998482E (pt) 2003-08-29
AU8758298A (en) 1999-02-16
TR199701051A3 (tr) 1999-03-22
US6512107B2 (en) 2003-01-28
ATE304547T1 (de) 2005-09-15
CN1206012A (zh) 1999-01-27
US6894159B2 (en) 2005-05-17
KR19990013297A (ko) 1999-02-25
ES2195370T3 (es) 2003-12-01
IL121730A (en) 2005-03-20
DE69831619T2 (de) 2006-06-14
TR199701051A2 (xx) 1999-03-22
IN186807B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 2001-11-10
DE69812959D1 (de) 2003-05-08
MY117314A (en) 2004-06-30
EP1327637A1 (en) 2003-07-16
ATE236187T1 (de) 2003-04-15
AR009092A1 (es) 2000-03-08
ES2249678T3 (es) 2006-04-01
TW434252B (en) 2001-05-16
EP1327637B1 (en) 2005-09-14
BR9810804A (pt) 2000-09-12
WO1999005158A1 (en) 1999-02-04
ID20624A (id) 1999-01-28
CN1113892C (zh) 2003-07-09
WO1999005157A1 (en) 1999-02-04
BR9810804B1 (pt) 2012-01-10
DE69812959T2 (de) 2004-03-04
US20020062018A1 (en) 2002-05-23
US20030139593A1 (en) 2003-07-24
SI1327637T1 (sl) 2005-12-31
KR100247505B1 (ko) 2000-03-15
EP0998482A1 (en) 2000-05-10
IL121730A0 (en) 1998-02-22
EP0998482B1 (en) 2003-04-02
DE69831619D1 (de) 2005-10-20
SA98180771B1 (ar) 2006-10-29
PT1327637E (pt) 2005-11-30

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