DK1314400T3 - Mikroporering af væv til levering af bioaktive midler - Google Patents
Mikroporering af væv til levering af bioaktive midlerInfo
- Publication number
- DK1314400T3 DK1314400T3 DK03002035T DK03002035T DK1314400T3 DK 1314400 T3 DK1314400 T3 DK 1314400T3 DK 03002035 T DK03002035 T DK 03002035T DK 03002035 T DK03002035 T DK 03002035T DK 1314400 T3 DK1314400 T3 DK 1314400T3
- Authority
- DK
- Denmark
- Prior art keywords
- microporation
- permeant
- tissues
- delivery
- organism
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/14507—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue specially adapted for measuring characteristics of body fluids other than blood
- A61B5/1451—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue specially adapted for measuring characteristics of body fluids other than blood for interstitial fluid
- A61B5/14514—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue specially adapted for measuring characteristics of body fluids other than blood for interstitial fluid using means for aiding extraction of interstitial fluid, e.g. microneedles or suction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
- A61K41/0047—Sonopheresis, i.e. ultrasonically-enhanced transdermal delivery, electroporation of a pharmacologically active agent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A61K9/0009—Galenical forms characterised by the drug release technique; Application systems commanded by energy involving or responsive to electricity, magnetism or acoustic waves; Galenical aspects of sonophoresis, iontophoresis, electroporation or electroosmosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0092—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin using ultrasonic, sonic or infrasonic vibrations, e.g. phonophoresis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B2017/00017—Electrical control of surgical instruments
- A61B2017/00137—Details of operation mode
- A61B2017/00154—Details of operation mode pulsed
- A61B2017/00172—Pulse trains, bursts, intermittent continuous operation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M2037/0007—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin having means for enhancing the permeation of substances through the epidermis, e.g. using suction or depression, electric or magnetic fields, sound waves or chemical agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Heart & Thoracic Surgery (AREA)
- Biophysics (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Dermatology (AREA)
- Medical Informatics (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- Hematology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Anesthesiology (AREA)
- Pathology (AREA)
- Molecular Biology (AREA)
- Surgery (AREA)
- Medicinal Preparation (AREA)
- Media Introduction/Drainage Providing Device (AREA)
- Radiation-Therapy Devices (AREA)
- Electrotherapy Devices (AREA)
- Measuring And Recording Apparatus For Diagnosis (AREA)
- Thermotherapy And Cooling Therapy Devices (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Surgical Instruments (AREA)
- Laser Surgery Devices (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US77841596A | 1996-12-31 | 1996-12-31 | |
PCT/US1997/011670 WO1998000193A1 (en) | 1996-07-03 | 1997-07-03 | Multiple mechanical microporation of skin or mucosa |
PCT/US1997/024127 WO1998029134A2 (en) | 1996-12-31 | 1997-12-30 | Microporation of tissue for delivery of bioactive agents |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1314400T3 true DK1314400T3 (da) | 2007-10-15 |
Family
ID=25113276
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK03002035T DK1314400T3 (da) | 1996-12-31 | 1997-12-30 | Mikroporering af væv til levering af bioaktive midler |
Country Status (9)
Country | Link |
---|---|
EP (2) | EP1314400B1 (ja) |
JP (5) | JP2001512329A (ja) |
AT (1) | ATE365026T1 (ja) |
AU (1) | AU5623298A (ja) |
CA (2) | CA2789115C (ja) |
DE (1) | DE69737836T2 (ja) |
DK (1) | DK1314400T3 (ja) |
ES (1) | ES2289192T3 (ja) |
WO (1) | WO1998029134A2 (ja) |
Families Citing this family (99)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK0921840T3 (da) * | 1996-07-03 | 2003-09-22 | Altea Therapeutics Corp | Multipel mekanisk mikroperforering af hud eller slimhinde |
US20060002949A1 (en) | 1996-11-14 | 2006-01-05 | Army Govt. Of The Usa, As Rep. By Secretary Of The Office Of The Command Judge Advocate, Hq Usamrmc. | Transcutaneous immunization without heterologous adjuvant |
US6517532B1 (en) | 1997-05-15 | 2003-02-11 | Palomar Medical Technologies, Inc. | Light energy delivery head |
US6527716B1 (en) | 1997-12-30 | 2003-03-04 | Altea Technologies, Inc. | Microporation of tissue for delivery of bioactive agents |
US6173202B1 (en) | 1998-03-06 | 2001-01-09 | Spectrx, Inc. | Method and apparatus for enhancing flux rates of a fluid in a microporated biological tissue |
WO1999064615A1 (en) * | 1998-06-08 | 1999-12-16 | Valentis, Inc. | Formulations for electroporation |
DE69939906D1 (de) | 1998-07-14 | 2008-12-24 | Altea Therapeutics Corp | Transdermale transportvorrichtung zum kontrollierten entfernen von biologischen membranen durch pyrotechnische ladung |
EP1148902A1 (en) * | 1999-01-22 | 2001-10-31 | PowderJect Research Limited | Method of enhancing needleless transdermal powdered drug delivery |
EP2286868A3 (en) * | 1999-06-08 | 2012-05-16 | Altea Therapeutics Corporation | Apparatus for microporation of biological membranes using thin film tissue interface devices, and method for manufacturing |
US6890553B1 (en) | 1999-07-08 | 2005-05-10 | Johnson & Johnson Consumer Companies, Inc. | Exothermic topical delivery device |
AU6076200A (en) | 1999-07-08 | 2001-01-30 | Johnson & Johnson Consumer Companies, Inc. | Exothermic bandage |
US20030078499A1 (en) | 1999-08-12 | 2003-04-24 | Eppstein Jonathan A. | Microporation of tissue for delivery of bioactive agents |
US7133717B2 (en) | 1999-08-25 | 2006-11-07 | Johnson & Johnson Consumer Companies, Inc. | Tissue electroperforation for enhanced drug delivery and diagnostic sampling |
US7113821B1 (en) * | 1999-08-25 | 2006-09-26 | Johnson & Johnson Consumer Companies, Inc. | Tissue electroperforation for enhanced drug delivery |
US7089053B1 (en) * | 1999-10-14 | 2006-08-08 | Pola Chemical Industries Inc | Compositions for drug administration by electroporation |
WO2001076553A2 (en) * | 2000-04-06 | 2001-10-18 | Sontra Medical, Inc. | Method and device for enhanced transdermal drug delivery |
US7404815B2 (en) | 2000-05-01 | 2008-07-29 | Lifescan, Inc. | Tissue ablation by shear force for sampling biological fluids and delivering active agents |
IL137689A0 (en) * | 2000-08-03 | 2001-10-31 | L R Res & Dev Ltd | System for enhanced chemical debridement |
AU2001288774B2 (en) * | 2000-09-08 | 2006-06-29 | Alza Corporation | Methods for inhibiting decrease in transdermal drug flux by inhibition of pathway closure |
US7632522B2 (en) | 2000-09-28 | 2009-12-15 | Nanocyte Inc. | Use of stinging cells/capsules for the delivery of active agents to keratinous substances |
EP1379127B1 (en) | 2000-09-28 | 2013-04-17 | Nanocyte Inc. | Methods, compositions and devices utilizing stinging cells/capsules for delivering a therapeutic or a cosmetic agent into a tissue |
US6882884B1 (en) | 2000-10-13 | 2005-04-19 | Soundskin, L.L.C. | Process for the stimulation of production of extracellular dermal proteins in human tissue |
US6794376B2 (en) * | 2000-12-06 | 2004-09-21 | William Beaumont Hospital | Methods and compositions for enhancing diffusion of therapeutic agents through tissue |
AU2002252378B2 (en) | 2001-03-19 | 2007-10-18 | Intercell Usa, Inc. | Transcutaneous immunostimulation |
JP2005530695A (ja) * | 2002-02-15 | 2005-10-13 | ザイコス インク. | 生理活性物質を細胞内に導入するエレクトロポレーション法 |
US9918665B2 (en) | 2002-03-11 | 2018-03-20 | Nitto Denko Corporation | Transdermal porator and patch system and method for using same |
ES2612779T3 (es) * | 2002-03-11 | 2017-05-18 | Nitto Denko Corporation | Sistema de parches transdérmicos de administración de fármacos, método de fabricación del mismo y método de uso del mismo |
AU2003215878A1 (en) | 2002-03-26 | 2003-10-08 | Nanocyte Inc. | Stinging cells expressing an exogenous polynucleotide encoding a therapeutic, diagnostic or a cosmetic agent and methods compositions and devices utilizing such stinging cells or capsules derived therefrom for delivering the therapeutic, diagnostic or cosmetic agent into a tissue |
EP1499255B1 (en) | 2002-04-19 | 2015-07-22 | Syneron Medical Ltd. | Handheld transdermal drug delivery and analyte extraction |
AU2003245573A1 (en) | 2002-06-19 | 2004-01-06 | Palomar Medical Technologies, Inc. | Method and apparatus for treatment of cutaneous and subcutaneous conditions |
US8016811B2 (en) | 2003-10-24 | 2011-09-13 | Altea Therapeutics Corporation | Method for transdermal delivery of permeant substances |
WO2006111201A1 (en) | 2005-04-18 | 2006-10-26 | Pantec Biosolutions Ag | Laser microporator |
US8834862B2 (en) | 2005-04-19 | 2014-09-16 | Nanocyte Inc. | Methods, compositions and devices utilizing stinging cells/capsules for conditioning a tissue prior to delivery of an active agent |
US7856985B2 (en) | 2005-04-22 | 2010-12-28 | Cynosure, Inc. | Method of treatment body tissue using a non-uniform laser beam |
US20070088248A1 (en) | 2005-09-02 | 2007-04-19 | Iomai Corporation | Devices for transcutaneous delivery of vaccines and transdermal delivery of drugs and uses thereof |
BRPI0616167A2 (pt) | 2005-09-15 | 2011-06-07 | Palomar Medical Tech Inc | dispositivo de caracterização ótica da pele |
JP4921795B2 (ja) | 2006-01-06 | 2012-04-25 | 株式会社東芝 | 超音波薬剤導入装置及び医用画像診断装置 |
US7586957B2 (en) | 2006-08-02 | 2009-09-08 | Cynosure, Inc | Picosecond laser apparatus and methods for its operation and use |
US20080077201A1 (en) | 2006-09-26 | 2008-03-27 | Juniper Medical, Inc. | Cooling devices with flexible sensors |
US9132031B2 (en) | 2006-09-26 | 2015-09-15 | Zeltiq Aesthetics, Inc. | Cooling device having a plurality of controllable cooling elements to provide a predetermined cooling profile |
US8192474B2 (en) | 2006-09-26 | 2012-06-05 | Zeltiq Aesthetics, Inc. | Tissue treatment methods |
US20100004582A1 (en) * | 2006-10-25 | 2010-01-07 | Pantec Biosolutions Ag | Wide-Area Parasystemic Treatment of Skin Related Conditions |
CA2925191C (en) | 2007-01-22 | 2018-07-24 | Nitto Denko Corporation | Transdermal porator and patch system and method for using same |
US20080287839A1 (en) | 2007-05-18 | 2008-11-20 | Juniper Medical, Inc. | Method of enhanced removal of heat from subcutaneous lipid-rich cells and treatment apparatus having an actuator |
US8523927B2 (en) | 2007-07-13 | 2013-09-03 | Zeltiq Aesthetics, Inc. | System for treating lipid-rich regions |
JP5474791B2 (ja) | 2007-08-21 | 2014-04-16 | ゼルティック エステティックス インコーポレイテッド | 脂肪組織の冷却のような皮下脂質リッチ細胞の冷却の監視 |
JP5466161B2 (ja) | 2007-10-09 | 2014-04-09 | トランスファーマ メディカル リミテッド | 磁気的なパッチ連結物 |
EP2205967B1 (en) | 2007-10-17 | 2013-05-01 | Syneron Medical Ltd. | Dissolution rate verification |
WO2009072108A2 (en) | 2007-12-05 | 2009-06-11 | Syneron Medical Ltd. | A disposable electromagnetic energy applicator and method of using it |
US8603073B2 (en) | 2008-12-17 | 2013-12-10 | Zeltiq Aesthetics, Inc. | Systems and methods with interrupt/resume capabilities for treating subcutaneous lipid-rich cells |
US8606366B2 (en) | 2009-02-18 | 2013-12-10 | Syneron Medical Ltd. | Skin treatment apparatus for personal use and method for using same |
JP5519000B2 (ja) | 2009-04-30 | 2014-06-11 | ゼルティック エステティックス インコーポレイテッド | 脂肪が豊富な皮下細胞から熱を除去するためのデバイス、システム、及び方法 |
US9919168B2 (en) | 2009-07-23 | 2018-03-20 | Palomar Medical Technologies, Inc. | Method for improvement of cellulite appearance |
US10238849B2 (en) | 2009-07-30 | 2019-03-26 | Alma Lasers Ltd. | Sonotrode |
US9014799B2 (en) * | 2009-10-08 | 2015-04-21 | Palo Alto Research Center Incorporated | Transmucosal drug delivery device and method including electrically-actuated permeation enhancement |
US8834423B2 (en) | 2009-10-23 | 2014-09-16 | University of Pittsburgh—of the Commonwealth System of Higher Education | Dissolvable microneedle arrays for transdermal delivery to human skin |
CN102791227A (zh) | 2010-01-25 | 2012-11-21 | 斯尔替克美学股份有限公司 | 用于通过相变冷却剂从皮下富脂细胞无创去除热量的家用施用器以及相关的装置、系统和方法 |
IE20110315A1 (en) * | 2010-07-13 | 2012-02-01 | Scott Mcnulty | System, method and apparatus for sensing biometric information |
US8676338B2 (en) | 2010-07-20 | 2014-03-18 | Zeltiq Aesthetics, Inc. | Combined modality treatment systems, methods and apparatus for body contouring applications |
WO2012028741A1 (en) | 2010-09-03 | 2012-03-08 | Intercell Ag | Isolated polypeptide of the toxin a and toxin b proteins of c. difficile and uses thereof |
WO2012103242A1 (en) | 2011-01-25 | 2012-08-02 | Zeltiq Aesthetics, Inc. | Devices, application systems and methods with localized heat flux zones for removing heat from subcutaneous lipid-rich cells |
KR102183581B1 (ko) | 2012-04-18 | 2020-11-27 | 싸이노슈어, 엘엘씨 | 피코초 레이저 장치 및 그를 사용한 표적 조직의 치료 방법 |
EP2841147A4 (en) * | 2012-05-01 | 2016-04-13 | Univ Pittsburgh | MICRO-NEEDLES NETWORKS WITH CHARGED END FOR TRANSDERMAL INSERTION |
US9545523B2 (en) | 2013-03-14 | 2017-01-17 | Zeltiq Aesthetics, Inc. | Multi-modality treatment systems, methods and apparatus for altering subcutaneous lipid-rich tissue |
US9844460B2 (en) | 2013-03-14 | 2017-12-19 | Zeltiq Aesthetics, Inc. | Treatment systems with fluid mixing systems and fluid-cooled applicators and methods of using the same |
EP3751684A1 (en) | 2013-03-15 | 2020-12-16 | Cynosure, Inc. | Picosecond optical radiation systems and methods of use |
US10517892B2 (en) * | 2013-10-22 | 2019-12-31 | Medtronic Minimed, Inc. | Methods and systems for inhibiting foreign-body responses in diabetic patients |
WO2015117032A1 (en) | 2014-01-31 | 2015-08-06 | Zeltiq Aesthestic, Inc. | Treatment systems for treating glands by cooling |
US10675176B1 (en) | 2014-03-19 | 2020-06-09 | Zeltiq Aesthetics, Inc. | Treatment systems, devices, and methods for cooling targeted tissue |
USD777338S1 (en) | 2014-03-20 | 2017-01-24 | Zeltiq Aesthetics, Inc. | Cryotherapy applicator for cooling tissue |
US9265260B1 (en) | 2014-04-07 | 2016-02-23 | Gpd Technologies Llc | Systems and methods for using light energy to facilitate penetration of substances in plants |
US11178823B2 (en) | 2014-04-07 | 2021-11-23 | Premier Citrus Apz, Llc | Systems and methods for using light energy to facilitate penetration of substances in plants |
US10278334B2 (en) | 2014-04-07 | 2019-05-07 | Premier Citrus Apz, Llc | Systems and methods for delivering nucleic acids to a plant |
US10952891B1 (en) | 2014-05-13 | 2021-03-23 | Zeltiq Aesthetics, Inc. | Treatment systems with adjustable gap applicators and methods for cooling tissue |
US10935174B2 (en) | 2014-08-19 | 2021-03-02 | Zeltiq Aesthetics, Inc. | Stress relief couplings for cryotherapy apparatuses |
US10568759B2 (en) | 2014-08-19 | 2020-02-25 | Zeltiq Aesthetics, Inc. | Treatment systems, small volume applicators, and methods for treating submental tissue |
US9459201B2 (en) | 2014-09-29 | 2016-10-04 | Zyomed Corp. | Systems and methods for noninvasive blood glucose and other analyte detection and measurement using collision computing |
US10441768B2 (en) | 2015-03-18 | 2019-10-15 | University of Pittsburgh—of the Commonwealth System of Higher Education | Bioactive components conjugated to substrates of microneedle arrays |
US11684763B2 (en) | 2015-10-16 | 2023-06-27 | University of Pittsburgh—of the Commonwealth System of Higher Education | Multi-component bio-active drug delivery and controlled release to the skin by microneedle array devices |
WO2017070112A1 (en) | 2015-10-19 | 2017-04-27 | Zeltiq Aesthetics, Inc. | Vascular treatment systems, cooling devices, and methods for cooling vascular structures |
CA3008016C (en) * | 2015-12-10 | 2020-06-30 | Premier Citrus Apz, Llc | Systems and methods for using light energy to facilitate penetration of substances in plants |
US11744889B2 (en) | 2016-01-05 | 2023-09-05 | University of Pittsburgh—of the Commonwealth System of Higher Education | Skin microenvironment targeted delivery for promoting immune and other responses |
US10524956B2 (en) | 2016-01-07 | 2020-01-07 | Zeltiq Aesthetics, Inc. | Temperature-dependent adhesion between applicator and skin during cooling of tissue |
US10765552B2 (en) | 2016-02-18 | 2020-09-08 | Zeltiq Aesthetics, Inc. | Cooling cup applicators with contoured heads and liner assemblies |
US11191278B2 (en) | 2016-03-25 | 2021-12-07 | Premier Citrus Apz, Llc | Systems and methods for delivering nucleic acids to a plant |
US9554738B1 (en) | 2016-03-30 | 2017-01-31 | Zyomed Corp. | Spectroscopic tomography systems and methods for noninvasive detection and measurement of analytes using collision computing |
US10555831B2 (en) | 2016-05-10 | 2020-02-11 | Zeltiq Aesthetics, Inc. | Hydrogel substances and methods of cryotherapy |
US10682297B2 (en) | 2016-05-10 | 2020-06-16 | Zeltiq Aesthetics, Inc. | Liposomes, emulsions, and methods for cryotherapy |
US11382790B2 (en) | 2016-05-10 | 2022-07-12 | Zeltiq Aesthetics, Inc. | Skin freezing systems for treating acne and skin conditions |
KR101929761B1 (ko) * | 2017-01-03 | 2018-12-17 | (주)엠큐어 | 약물주입홀이 형성된 니들모듈 |
KR101938187B1 (ko) * | 2017-01-03 | 2019-01-14 | (주)엠큐어 | 약물주입홀의 개폐가 가능한 니들모듈 |
CN110582245B (zh) | 2017-03-27 | 2022-09-16 | 诺服塞尔有限公司 | 用于皮内溶液递送的系统、设备和方法 |
US11076879B2 (en) | 2017-04-26 | 2021-08-03 | Zeltiq Aesthetics, Inc. | Shallow surface cryotherapy applicators and related technology |
WO2019165426A1 (en) | 2018-02-26 | 2019-08-29 | Cynosure, Inc. | Q-switched cavity dumped sub-nanosecond laser |
CN110604867A (zh) * | 2018-06-15 | 2019-12-24 | 博健通大健康(深圳)有限公司 | 一种超声中频导药仪 |
AU2019315940A1 (en) | 2018-07-31 | 2021-03-04 | Zeltiq Aesthetics, Inc. | Methods, devices, and systems for improving skin characteristics |
US11622943B2 (en) * | 2019-05-10 | 2023-04-11 | Chamkurkishtiah Panduranga Rao | System and method for allergen-specific epicutaneous immunotherapy |
CN112490602B (zh) * | 2020-10-19 | 2021-09-24 | 电子科技大学 | 一种基于多层结构的THz导波调控装置 |
WO2023161966A1 (en) * | 2022-02-24 | 2023-08-31 | Teoresi S.P.A. | Device for inducing cell permeability in a portion of tissue by opto-poration |
Family Cites Families (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5850905Y2 (ja) * | 1981-05-27 | 1983-11-19 | 桜アルミ株式会社 | 温熱治療器 |
JPS58121943A (ja) * | 1982-01-16 | 1983-07-20 | 小林 敏男 | 高周波脱毛装置用脱毛針 |
JPS6268466A (ja) * | 1985-09-24 | 1987-03-28 | 大盛商事株式会社 | つぼ当て治療器 |
US4775361A (en) * | 1986-04-10 | 1988-10-04 | The General Hospital Corporation | Controlled removal of human stratum corneum by pulsed laser to enhance percutaneous transport |
US5749847A (en) * | 1988-01-21 | 1998-05-12 | Massachusetts Institute Of Technology | Delivery of nucleotides into organisms by electroporation |
EP0398960B1 (en) * | 1988-01-21 | 1995-12-06 | Massachusetts Institute Of Technology | Transport of molecules across tissue using electroporation |
US5115805A (en) * | 1990-02-23 | 1992-05-26 | Cygnus Therapeutic Systems | Ultrasound-enhanced delivery of materials into and through the skin |
JPH04150871A (ja) * | 1990-10-12 | 1992-05-25 | Azusa Eng:Kk | 流動磁場応用健康用具 |
IT1244667B (it) * | 1991-03-28 | 1994-08-08 | Enea | Procedimento di microperforazione laser di cellule. |
CA2066963A1 (en) * | 1991-05-15 | 1992-11-16 | Norio Daikuzono | Laser light irradiation apparatus |
US5225282A (en) * | 1991-12-13 | 1993-07-06 | Molecular Bioquest, Inc. | Biodegradable magnetic microcluster comprising non-magnetic metal or metal oxide particles coated with a functionalized polymer |
JP3368603B2 (ja) * | 1992-02-28 | 2003-01-20 | オリンパス光学工業株式会社 | 遺伝子治療用処置具 |
WO1993021841A1 (en) * | 1992-04-24 | 1993-11-11 | Surgical Laser Technologies, Inc. | Medical device |
US5342355A (en) * | 1992-10-19 | 1994-08-30 | Laser Centers Of America | Energy delivering cap element for end of optic fiber conveying laser energy |
US5643252A (en) * | 1992-10-28 | 1997-07-01 | Venisect, Inc. | Laser perforator |
US5458140A (en) * | 1993-11-15 | 1995-10-17 | Non-Invasive Monitoring Company (Nimco) | Enhancement of transdermal monitoring applications with ultrasound and chemical enhancers |
AU1958295A (en) * | 1994-04-13 | 1995-11-10 | Novartis Ag | Temporally controlled drug delivery systems |
CA2194010A1 (en) * | 1994-06-24 | 1996-01-04 | Ooi Wong | Pulsatile delivery systems of biologically active agents using electro voltage pulsing for controlling membrane permeability |
US5586981A (en) * | 1994-08-25 | 1996-12-24 | Xin-Hua Hu | Treatment of cutaneous vascular and pigmented lesions |
AU5869796A (en) * | 1995-05-22 | 1996-12-11 | Ned A. Godshall | Micromechanical patch for enhancing the delivery of compound s through the skin |
CA2200984A1 (en) * | 1995-07-25 | 1997-02-13 | Samir S. Mitragotri | Enhanced transdermal transfer using ultrasound |
CN1174713C (zh) * | 1995-08-29 | 2004-11-10 | 光谱股份有限公司 | 用于输药及检测的人体皮肤微穿孔设备 |
DK0921840T3 (da) * | 1996-07-03 | 2003-09-22 | Altea Therapeutics Corp | Multipel mekanisk mikroperforering af hud eller slimhinde |
-
1997
- 1997-12-30 AT AT03002035T patent/ATE365026T1/de active
- 1997-12-30 ES ES03002035T patent/ES2289192T3/es not_active Expired - Lifetime
- 1997-12-30 DE DE69737836T patent/DE69737836T2/de not_active Expired - Lifetime
- 1997-12-30 EP EP03002035A patent/EP1314400B1/en not_active Expired - Lifetime
- 1997-12-30 WO PCT/US1997/024127 patent/WO1998029134A2/en not_active Application Discontinuation
- 1997-12-30 EP EP97952676A patent/EP0952850A2/en not_active Ceased
- 1997-12-30 AU AU56232/98A patent/AU5623298A/en not_active Abandoned
- 1997-12-30 CA CA2789115A patent/CA2789115C/en not_active Expired - Lifetime
- 1997-12-30 CA CA2276312A patent/CA2276312C/en not_active Expired - Lifetime
- 1997-12-30 JP JP53029898A patent/JP2001512329A/ja not_active Withdrawn
- 1997-12-30 DK DK03002035T patent/DK1314400T3/da active
-
2008
- 2008-06-16 JP JP2008157298A patent/JP2008307391A/ja not_active Withdrawn
-
2009
- 2009-09-02 JP JP2009203124A patent/JP2010005425A/ja not_active Withdrawn
-
2013
- 2013-01-31 JP JP2013016445A patent/JP5657040B2/ja not_active Expired - Fee Related
- 2013-03-08 JP JP2013046499A patent/JP5680685B2/ja not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
CA2276312A1 (en) | 1998-07-09 |
EP0952850A2 (en) | 1999-11-03 |
ES2289192T3 (es) | 2008-02-01 |
EP1314400A3 (en) | 2003-10-15 |
WO1998029134A3 (en) | 1998-10-15 |
JP2010005425A (ja) | 2010-01-14 |
EP1314400B1 (en) | 2007-06-20 |
CA2789115A1 (en) | 1998-07-09 |
CA2276312C (en) | 2012-11-27 |
JP2013165967A (ja) | 2013-08-29 |
JP2008307391A (ja) | 2008-12-25 |
CA2789115C (en) | 2014-04-29 |
ATE365026T1 (de) | 2007-07-15 |
JP5657040B2 (ja) | 2015-01-21 |
JP2013099586A (ja) | 2013-05-23 |
EP1314400A2 (en) | 2003-05-28 |
DE69737836T2 (de) | 2008-03-06 |
AU5623298A (en) | 1998-07-31 |
WO1998029134A2 (en) | 1998-07-09 |
JP2001512329A (ja) | 2001-08-21 |
DE69737836D1 (de) | 2007-08-02 |
JP5680685B2 (ja) | 2015-03-04 |
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