DK127420B - Analogifremgangsmåde til fremstilling af 6α-fluor-16α,18-dimethyl-1,4-pregnadien-3,20-dionderivater. - Google Patents

Analogifremgangsmåde til fremstilling af 6α-fluor-16α,18-dimethyl-1,4-pregnadien-3,20-dionderivater.

Info

Publication number
DK127420B
DK127420B DK573271AA DK573271A DK127420B DK 127420 B DK127420 B DK 127420B DK 573271A A DK573271A A DK 573271AA DK 573271 A DK573271 A DK 573271A DK 127420 B DK127420 B DK 127420B
Authority
DK
Denmark
Prior art keywords
pregnadiene
fluoro
dimethyl
preparation
dione derivatives
Prior art date
Application number
DK573271AA
Other languages
Danish (da)
English (en)
Inventor
U Kerb
R Wiechert
K Petzoldt
K Kieslich
K Kolb
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of DK127420B publication Critical patent/DK127420B/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J7/00Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J5/00Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J1/00Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J3/00Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J41/00Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0077Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 substituted in position 11-beta by a carbon atom, further substituted by a group comprising at least one further carbon atom
    • C07J41/0083Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 substituted in position 11-beta by a carbon atom, further substituted by a group comprising at least one further carbon atom substituted in position 11-beta by an optionally substituted phenyl group not further condensed with other rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J5/00Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0007Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa
    • C07J5/0023Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa substituted in position 16
    • C07J5/003Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group including 16-alkylidene substitutes
    • C07J5/0038Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group including 16-alkylidene substitutes by an alkyl group
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J5/00Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
DK573271AA 1970-12-30 1971-11-23 Analogifremgangsmåde til fremstilling af 6α-fluor-16α,18-dimethyl-1,4-pregnadien-3,20-dionderivater. DK127420B (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2064859A DE2064859C3 (de) 1970-12-30 1970-12-30 Neue 6 a -Fluor-16 a , 18dimethyl-l,4-pregnadien-3,20-dion Derivate, Verfahren zu ihrer Herstellung sowie diese enthaltende Arzneimittel

Publications (1)

Publication Number Publication Date
DK127420B true DK127420B (da) 1973-11-05

Family

ID=5792810

Family Applications (1)

Application Number Title Priority Date Filing Date
DK573271AA DK127420B (da) 1970-12-30 1971-11-23 Analogifremgangsmåde til fremstilling af 6α-fluor-16α,18-dimethyl-1,4-pregnadien-3,20-dionderivater.

Country Status (20)

Country Link
US (1) US3787454A (xx)
AT (1) AT312823B (xx)
AU (1) AU464245B2 (xx)
BE (1) BE777549A (xx)
CA (1) CA947277A (xx)
CH (1) CH571539A5 (xx)
CS (1) CS166792B2 (xx)
DE (1) DE2064859C3 (xx)
DK (1) DK127420B (xx)
EG (1) EG10342A (xx)
FI (1) FI49160C (xx)
FR (1) FR2120112B1 (xx)
GB (1) GB1378168A (xx)
HU (1) HU163052B (xx)
IE (1) IE35896B1 (xx)
IL (1) IL38473A (xx)
NL (1) NL7118166A (xx)
SE (1) SE377804B (xx)
SU (2) SU468409A3 (xx)
ZA (1) ZA717774B (xx)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1036870B (it) * 1975-02-13 1979-10-30 Acraf Derivati steroidei dell acido bendazolico
CH633562A5 (de) * 1976-12-10 1982-12-15 Schering Ag Verfahren zur herstellung neuer kortikoide.
US4740372A (en) * 1986-09-17 1988-04-26 Ljubomir Boncic Composition for treating psoriasis vulgaris and a method for its preparation

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1643036B2 (de) * 1967-08-16 1976-04-15 Schering Ag, 1000 Berlin Und 4619 Bergkamen Neue 11 beta-halogensteroide, diese enthaltende arzneimittel sowie verfahren zu ihrer herstellung
US3529000A (en) * 1968-01-29 1970-09-15 American Home Prod C-21 hydroxylation products of steroids

Also Published As

Publication number Publication date
BE777549A (fr) 1972-06-30
IE35896L (en) 1972-06-30
SE377804B (xx) 1975-07-28
SU504493A4 (ru) 1976-02-25
FR2120112B1 (xx) 1975-04-18
DE2064859B2 (de) 1979-09-13
HU163052B (xx) 1973-05-28
FI49160C (fi) 1975-04-10
CS166792B2 (xx) 1976-03-29
NL7118166A (xx) 1972-07-04
ZA717774B (en) 1972-08-30
CH571539A5 (xx) 1976-01-15
AT312823B (de) 1974-01-25
GB1378168A (en) 1974-12-27
IL38473A (en) 1975-08-31
DE2064859A1 (de) 1972-07-20
US3787454A (en) 1974-01-22
DE2064859C3 (de) 1980-05-22
FR2120112A1 (xx) 1972-08-11
IL38473A0 (en) 1972-02-29
IE35896B1 (en) 1976-06-23
AU464245B2 (en) 1975-08-04
FI49160B (xx) 1974-12-31
SU468409A3 (ru) 1975-04-25
CA947277A (en) 1974-05-14
AU3608271A (en) 1973-05-31
PL74486B1 (xx) 1974-10-30
EG10342A (en) 1976-05-31

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